Four of the five prayers are tied to sunrise and sunset. So depending of which shift you are on and time of year one to four could occur during a work shift. There are apps that tell the best minute to start praying. However in a large organization you could probably round it to the best quarter hour (strict people might demur). In Muslim cities, the whole city takes a coordinated break.
I wonder what they do in some Detroit area schools where as many as half of the students may be Muslim.