The mechanics if I understand the Constitution on this make it unlikely to happen unless he has a sudden public mental psychotic breakdown (yes...I know what some will say....). While I could imagine Pence and the adult Cabinet members like Mattis, Tillerson, Kelly, etc...being strong enough to revolt for the good of the country, I cannot fathom people like DeVos, Mnuchin, Pruit and others of that ilk ever being strong enough to turn against their man.