In the near future, alcohol is going to be demonized by the reality that it destroys your health through destroying your gut and intestinal bacteria. Recent studies have shown that 5 shots of alcohol in healthy males negatively affected their health. This is determined by blood samples taken every 30 minutes for four hours after and again 24 hours later. The study shows that the alcohol binge resulted in increased gut permeability (leaky gut) and elevations of endotoxin levels. That was one event of drinking. If you are a heavy drinker and have an autoimmune disease you may be causing yourself harm through the inflammation caused by drinking. 
Thank goodness for cannabis, because using it in the form of edibles is safe with no known or associative problems provided you have set your limitations to reasonable expectations.