No, just natural realities.

We get sick, we have headaches and sores, we get terminal illness.

The question is:  Have you learned how to sanctify all the realities that God allows in your life?

Here's one:  People make silly or cutting or sarcastic remarks for various reasons and deficiencies.   

Well formed Catholics say: It's our own defects that make us unhappy. I refuse to let this person's small or cutting or cynical or snide remarks dampen my cheer at all.  I am an adopted and loved child of God. Nothing can shake my joy.  God is my Father after all.

And so rather than getting sad or upset when someone makes a small or sarcastic or cutting remark, the well formed Catholic simply integrates this experience with the suffering that Jesus happily took on for us.  

We unite our suffering with us, and we are joyful because of this intimacy we share with Joy Himself.