You don't seem to understand that nearly all the deaths were caused by disease, not human actions.  Human causes were insignificant in comparison. 

And many of the deaths inflicted by white men were self-defense.  Natives were often  hostile towards white settlers, & were well known for committing savage atrocities & slaughter of white settlers in Oregon.

The Rogue River War reminds me a lot of the current Israeli-Palestinian conflict.  One side would attack, then the other would retaliate back.  There were some early bad men from the Hudson Bay Company who murdered natives, and there was an American named Ewing Young who also murdered.  They sort of got the bad blood started.

But the fact is that the natives then often retaliated against totally innocent settlers that had nothing at all to do with earlier attacks on them.  Sometimes as much as a year after they were attacked.  It became a cycle of revenge,

They looked at all white people the same way that the Charles family does.