No.  Life experiences do not change DNA.  Male/Female is in the DNA/genes and cannot be changed.

Even doctors admit that transgender surgery can only make the person's body appear to be the gender they "identity" with, but it cannot change the gender.  That means a man who "becomes" a women is still a man--he just looks female--and visa-versa.  One might be able to change their sex--if sex is defined as the gender a person identifies.  Gender itself, however cannot be changed.  

Even people that have had transgender surgery have admitted this.  They knew in their heart of hearts even after the surgery that despite the legal documents, etc, despite appearances they were still the gender they were born with.  

The idea that DNA can change through life experiences is hogwash.