The biggest concern I have is what is the cardiovascular rate in women in similar age groups who DID NOT undergo fertility treatments. If both  groups ie women giving birth within a year of fertility treatment and women not giving birth after fertility treatment, have statistically/clinically significant increase risk of cardiovascular events ie heart failure etc. then should this "chronic disease inducing" treatment continue? Women should be made aware, that they may have kids in their early 40's but have a higher risk of chronic debilitating illness.