Francesca ha fatto notare a Maria che (pro) era molto stanca .
F.FEM.SG . AUX.IND.PRS.3SG . make.PST.PTCP . realize.INF . to M.FEM.SG . that pro be.IND.IPFV.3SG . very tired.FEM.SG . 
Francesca made Maria realize that (she) was very tired.