{"action":"closed","issue":{"url":"https://api.github.com/repos/denovogear/denovogear/issues/67","repository_url":"https://api.github.com/repos/denovogear/denovogear","labels_url":"https://api.github.com/repos/denovogear/denovogear/issues/67/labels{/name}","comments_url":"https://api.github.com/repos/denovogear/denovogear/issues/67/comments","events_url":"https://api.github.com/repos/denovogear/denovogear/issues/67/events","html_url":"https://github.com/denovogear/denovogear/issues/67","id":113965523,"node_id":"MDU6SXNzdWUxMTM5NjU1MjM=","number":67,"title":"Call somatic mutations when you don't know the tree.","user":{"login":"reedacartwright","id":101918,"node_id":"MDQ6VXNlcjEwMTkxOA==","avatar_url":"https://avatars0.githubusercontent.com/u/101918?v=4","gravatar_id":"","url":"https://api.github.com/users/reedacartwright","html_url":"https://github.com/reedacartwright","followers_url":"https://api.github.com/users/reedacartwright/followers","following_url":"https://api.github.com/users/reedacartwright/following{/other_user}","gists_url":"https://api.github.com/users/reedacartwright/gists{/gist_id}","starred_url":"https://api.github.com/users/reedacartwright/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/reedacartwright/subscriptions","organizations_url":"https://api.github.com/users/reedacartwright/orgs","repos_url":"https://api.github.com/users/reedacartwright/repos","events_url":"https://api.github.com/users/reedacartwright/events{/privacy}","received_events_url":"https://api.github.com/users/reedacartwright/received_events","type":"User","site_admin":false},"labels":[{"id":400202686,"node_id":"MDU6TGFiZWw0MDAyMDI2ODY=","url":"https://api.github.com/repos/denovogear/denovogear/labels/Type-Research","name":"Type-Research","color":"c2e0c6","default":false},{"id":71314576,"node_id":"MDU6TGFiZWw3MTMxNDU3Ng==","url":"https://api.github.com/repos/denovogear/denovogear/labels/enhancement","name":"enhancement","color":"84b6eb","default":true}],"state":"closed","locked":false,"assignee":null,"assignees":[],"milestone":null,"comments":1,"created_at":"2015-10-29T02:29:09Z","updated_at":"2018-05-31T03:37:18Z","closed_at":"2018-05-31T03:37:17Z","author_association":"CONTRIBUTOR","body":"A star tree produces too low of a probability if used in place of a large tissue tree.\n\nPossible Solutions\n- Use something other than DNG to call sample variants.\n- Use a dirichlet-multinomial caller to treat somatic variants as coming from a population.\n"}}
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