{"action":"created","issue":{"url":"https://api.github.com/repos/brian-team/brian2/issues/491","repository_url":"https://api.github.com/repos/brian-team/brian2","labels_url":"https://api.github.com/repos/brian-team/brian2/issues/491/labels{/name}","comments_url":"https://api.github.com/repos/brian-team/brian2/issues/491/comments","events_url":"https://api.github.com/repos/brian-team/brian2/issues/491/events","html_url":"https://github.com/brian-team/brian2/issues/491","id":91827716,"number":491,"title":"Integration of Markov channel models","user":{"login":"romainbrette","id":2903502,"avatar_url":"https://avatars0.githubusercontent.com/u/2903502?v=4","gravatar_id":"","url":"https://api.github.com/users/romainbrette","html_url":"https://github.com/romainbrette","followers_url":"https://api.github.com/users/romainbrette/followers","following_url":"https://api.github.com/users/romainbrette/following{/other_user}","gists_url":"https://api.github.com/users/romainbrette/gists{/gist_id}","starred_url":"https://api.github.com/users/romainbrette/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/romainbrette/subscriptions","organizations_url":"https://api.github.com/users/romainbrette/orgs","repos_url":"https://api.github.com/users/romainbrette/repos","events_url":"https://api.github.com/users/romainbrette/events{/privacy}","received_events_url":"https://api.github.com/users/romainbrette/received_events","type":"User","site_admin":false},"labels":[{"id":20465126,"url":"https://api.github.com/repos/brian-team/brian2/labels/enhancement","name":"enhancement","color":"207de5","default":true},{"id":42520159,"url":"https://api.github.com/repos/brian-team/brian2/labels/proposal","name":"proposal","color":"fbca04","default":false}],"state":"open","locked":false,"assignee":null,"assignees":[],"milestone":null,"comments":3,"created_at":"2015-06-29T14:54:09Z","updated_at":"2018-03-14T11:28:01Z","closed_at":null,"author_association":"OWNER","body":"To accurately account for channel noise requires considering Markov models of ionic channels (there's a paper showing that Langevin approximations are not good enough). The standard method is described in Chow & White (Biophysical Journal 1996). We might require new syntax (a couple of flags probably).\n"},"comment":{"url":"https://api.github.com/repos/brian-team/brian2/issues/comments/372989336","html_url":"https://github.com/brian-team/brian2/issues/491#issuecomment-372989336","issue_url":"https://api.github.com/repos/brian-team/brian2/issues/491","id":372989336,"user":{"login":"ttxtea","id":7713616,"avatar_url":"https://avatars2.githubusercontent.com/u/7713616?v=4","gravatar_id":"","url":"https://api.github.com/users/ttxtea","html_url":"https://github.com/ttxtea","followers_url":"https://api.github.com/users/ttxtea/followers","following_url":"https://api.github.com/users/ttxtea/following{/other_user}","gists_url":"https://api.github.com/users/ttxtea/gists{/gist_id}","starred_url":"https://api.github.com/users/ttxtea/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/ttxtea/subscriptions","organizations_url":"https://api.github.com/users/ttxtea/orgs","repos_url":"https://api.github.com/users/ttxtea/repos","events_url":"https://api.github.com/users/ttxtea/events{/privacy}","received_events_url":"https://api.github.com/users/ttxtea/received_events","type":"User","site_admin":false},"created_at":"2018-03-14T11:28:01Z","updated_at":"2018-03-14T11:28:01Z","author_association":"NONE","body":"Hi, so we basically have some code for doing the diffustion approximations automatically and then simmulating those in brian. An actually Gillespie implementation for `brian` would probably be more complicated.\r\n\r\nAs for the notation. IMO, it is very usefull to be compatible with either [dot language](the https://en.wikipedia.org/wiki/DOT_%28graph_description_language%29). Or something that the python package [networkx](https://networkx.github.io/) can read (i.e. json)."}}
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