{"action":"created","issue":{"url":"https://api.github.com/repos/geneontology/go-ontology/issues/15494","repository_url":"https://api.github.com/repos/geneontology/go-ontology","labels_url":"https://api.github.com/repos/geneontology/go-ontology/issues/15494/labels{/name}","comments_url":"https://api.github.com/repos/geneontology/go-ontology/issues/15494/comments","events_url":"https://api.github.com/repos/geneontology/go-ontology/issues/15494/events","html_url":"https://github.com/geneontology/go-ontology/issues/15494","id":309462452,"number":15494,"title":"amyloid precursor protein metabolic 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an odd term (isn't it just protein maturation?)\r\n\r\nif it is required, shouldn't it be a child of this?\r\nhttps://www.ebi.ac.uk/QuickGO/term/GO:0051604\r\n@RLovering "},"comment":{"url":"https://api.github.com/repos/geneontology/go-ontology/issues/comments/380517488","html_url":"https://github.com/geneontology/go-ontology/issues/15494#issuecomment-380517488","issue_url":"https://api.github.com/repos/geneontology/go-ontology/issues/15494","id":380517488,"user":{"login":"BarbaraCzub","id":16541096,"avatar_url":"https://avatars2.githubusercontent.com/u/16541096?v=4","gravatar_id":"","url":"https://api.github.com/users/BarbaraCzub","html_url":"https://github.com/BarbaraCzub","followers_url":"https://api.github.com/users/BarbaraCzub/followers","following_url":"https://api.github.com/users/BarbaraCzub/following{/other_user}","gists_url":"https://api.github.com/users/BarbaraCzub/gists{/gist_id}","starred_url":"https://api.github.com/users/BarbaraCzub/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/BarbaraCzub/subscriptions","organizations_url":"https://api.github.com/users/BarbaraCzub/orgs","repos_url":"https://api.github.com/users/BarbaraCzub/repos","events_url":"https://api.github.com/users/BarbaraCzub/events{/privacy}","received_events_url":"https://api.github.com/users/BarbaraCzub/received_events","type":"User","site_admin":false},"created_at":"2018-04-11T16:38:44Z","updated_at":"2018-04-11T16:38:44Z","author_association":"CONTRIBUTOR","body":"I agree that the definition suggests that the term 'amyloid precursor protein biosynthetic process' actually refers to maturation of APP, as it mentions APP is a glycoprotein.\r\nThere are only 8 manual experimental annotations to '_positive/negative regulation of_ amyloid precursor protein biosynthetic process' (I found no direct annotations to 'amyloid precursor protein biosynthetic process').\r\n\r\n<img width=\"1136\" alt=\"screen shot 2018-04-11 at 14 21 07\" src=\"https://user-images.githubusercontent.com/16541096/38619240-a17d2006-3d93-11e8-9b3d-5df01c5894a6.png\">\r\n\r\nI'll revise these annotations and make sure that they'll still be correct, if 'amyloid precursor protein biosynthetic process' is renamed as 'amyloid precursor protein maturation' (and the regulation child terms are renamed accordingly). \r\n\r\nIf the existing 8 annotations appear to be based on regulation of APP maturation (rather than biosynthesis of the APP peptide chain), then I'll rename 'amyloid precursor protein biosynthetic process' as 'amyloid precursor protein maturation', and I'll make it a child of 'protein maturation'. \r\n\r\n@ukemi do you agree this is the right approach?\r\n\r\ncc @RLovering "}}
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