{"action":"created","issue":{"url":"https://api.github.com/repos/Illumina/strelka/issues/32","repository_url":"https://api.github.com/repos/Illumina/strelka","labels_url":"https://api.github.com/repos/Illumina/strelka/issues/32/labels{/name}","comments_url":"https://api.github.com/repos/Illumina/strelka/issues/32/comments","events_url":"https://api.github.com/repos/Illumina/strelka/issues/32/events","html_url":"https://github.com/Illumina/strelka/issues/32","id":297554543,"number":32,"title":"Strelka2 crashes on targeted sequencing experiment","user":{"login":"PedroBarbosa","id":4269608,"avatar_url":"https://avatars2.githubusercontent.com/u/4269608?v=4","gravatar_id":"","url":"https://api.github.com/users/PedroBarbosa","html_url":"https://github.com/PedroBarbosa","followers_url":"https://api.github.com/users/PedroBarbosa/followers","following_url":"https://api.github.com/users/PedroBarbosa/following{/other_user}","gists_url":"https://api.github.com/users/PedroBarbosa/gists{/gist_id}","starred_url":"https://api.github.com/users/PedroBarbosa/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/PedroBarbosa/subscriptions","organizations_url":"https://api.github.com/users/PedroBarbosa/orgs","repos_url":"https://api.github.com/users/PedroBarbosa/repos","events_url":"https://api.github.com/users/PedroBarbosa/events{/privacy}","received_events_url":"https://api.github.com/users/PedroBarbosa/received_events","type":"User","site_admin":false},"labels":[],"state":"open","locked":false,"assignee":null,"assignees":[],"milestone":null,"comments":4,"created_at":"2018-02-15T18:44:55Z","updated_at":"2018-02-19T10:33:48Z","closed_at":null,"author_association":"NONE","body":"Hello,\r\n\r\nI've read your guide, and I knew beforehand that strelka2 is not intended to run germline analysis in a larger scale. Anyway, I decided to give it a try (I have a set of around 800 case samples for a small panel of 40 genes), and I would like to know if the error I'm facing has to do with this known limitation, or may it be something else I'm missing.\r\n\r\nPlease find attached the last 50 lines of log of the run. (Full log is 35Mb big)\r\n[strelka2.log](https://github.com/Illumina/strelka/files/1728943/strelka2.log)\r\n\r\nThanks in advance,\r\nBest,\r\nPedro\r\n"},"comment":{"url":"https://api.github.com/repos/Illumina/strelka/issues/comments/366649438","html_url":"https://github.com/Illumina/strelka/issues/32#issuecomment-366649438","issue_url":"https://api.github.com/repos/Illumina/strelka/issues/32","id":366649438,"user":{"login":"PedroBarbosa","id":4269608,"avatar_url":"https://avatars2.githubusercontent.com/u/4269608?v=4","gravatar_id":"","url":"https://api.github.com/users/PedroBarbosa","html_url":"https://github.com/PedroBarbosa","followers_url":"https://api.github.com/users/PedroBarbosa/followers","following_url":"https://api.github.com/users/PedroBarbosa/following{/other_user}","gists_url":"https://api.github.com/users/PedroBarbosa/gists{/gist_id}","starred_url":"https://api.github.com/users/PedroBarbosa/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/PedroBarbosa/subscriptions","organizations_url":"https://api.github.com/users/PedroBarbosa/orgs","repos_url":"https://api.github.com/users/PedroBarbosa/repos","events_url":"https://api.github.com/users/PedroBarbosa/events{/privacy}","received_events_url":"https://api.github.com/users/PedroBarbosa/received_events","type":"User","site_admin":false},"created_at":"2018-02-19T10:33:48Z","updated_at":"2018-02-19T10:33:48Z","author_association":"NONE","body":"@ctsa , 2 out of 12 jobs failed.  Maybe 75 samples is still too much ? \r\n[workflow.error.log.txt](https://github.com/Illumina/strelka/files/1736335/workflow.error.log.txt)\r\n\r\nI want to try it @jaredo, will get in touch when all the variants are called."}}
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