{"action":"opened","issue":{"url":"https://api.github.com/repos/Illumina/strelka/issues/48","repository_url":"https://api.github.com/repos/Illumina/strelka","labels_url":"https://api.github.com/repos/Illumina/strelka/issues/48/labels{/name}","comments_url":"https://api.github.com/repos/Illumina/strelka/issues/48/comments","events_url":"https://api.github.com/repos/Illumina/strelka/issues/48/events","html_url":"https://github.com/Illumina/strelka/issues/48","id":326578078,"number":48,"title":"Different results after upgrading from Strelka2.7.1 to 2.9.2","user":{"login":"makarov-mskcc","id":13528046,"avatar_url":"https://avatars3.githubusercontent.com/u/13528046?v=4","gravatar_id":"","url":"https://api.github.com/users/makarov-mskcc","html_url":"https://github.com/makarov-mskcc","followers_url":"https://api.github.com/users/makarov-mskcc/followers","following_url":"https://api.github.com/users/makarov-mskcc/following{/other_user}","gists_url":"https://api.github.com/users/makarov-mskcc/gists{/gist_id}","starred_url":"https://api.github.com/users/makarov-mskcc/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/makarov-mskcc/subscriptions","organizations_url":"https://api.github.com/users/makarov-mskcc/orgs","repos_url":"https://api.github.com/users/makarov-mskcc/repos","events_url":"https://api.github.com/users/makarov-mskcc/events{/privacy}","received_events_url":"https://api.github.com/users/makarov-mskcc/received_events","type":"User","site_admin":false},"labels":[],"state":"open","locked":false,"assignee":null,"assignees":[],"milestone":null,"comments":0,"created_at":"2018-05-25T15:52:30Z","updated_at":"2018-05-25T15:52:30Z","closed_at":null,"author_association":"NONE","body":"Dear developers,\r\n\r\nAfter I upgraded from Strelka2.7.1 to 2.9.2 (via conda), I am getting quite different somatic calls for INDELS. Even though total number is close (200 vs 217), only 14 overlap when I compare coordinates. I also checked configureStrelkaSomaticWorkflow files, they are identical, with only difference that 2.9.2 has \"maxIndelSize = 49\" parameter.\r\n\r\nWhat can de the reason of that?\r\n\r\nThank you\r\n\r\nVlad\r\n\r\n\r\n"}}
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