{"action":"created","issue":{"url":"https://api.github.com/repos/geneontology/go-ontology/issues/9993","repository_url":"https://api.github.com/repos/geneontology/go-ontology","labels_url":"https://api.github.com/repos/geneontology/go-ontology/issues/9993/labels{/name}","comments_url":"https://api.github.com/repos/geneontology/go-ontology/issues/9993/comments","events_url":"https://api.github.com/repos/geneontology/go-ontology/issues/9993/events","html_url":"https://github.com/geneontology/go-ontology/issues/9993","id":97260659,"number":9993,"title":"what does \"signal transducer activity\" mean?","user":{"login":"gocentral","id":12972975,"avatar_url":"https://avatars.githubusercontent.com/u/12972975?v=3","gravatar_id":"","url":"https://api.github.com/users/gocentral","html_url":"https://github.com/gocentral","followers_url":"https://api.github.com/users/gocentral/followers","following_url":"https://api.github.com/users/gocentral/following{/other_user}","gists_url":"https://api.github.com/users/gocentral/gists{/gist_id}","starred_url":"https://api.github.com/users/gocentral/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/gocentral/subscriptions","organizations_url":"https://api.github.com/users/gocentral/orgs","repos_url":"https://api.github.com/users/gocentral/repos","events_url":"https://api.github.com/users/gocentral/events{/privacy}","received_events_url":"https://api.github.com/users/gocentral/received_events","type":"User","site_admin":false},"labels":[{"url":"https://api.github.com/repos/geneontology/go-ontology/labels/auto-migrated","name":"auto-migrated","color":"ededed"},{"url":"https://api.github.com/repos/geneontology/go-ontology/labels/jamboree","name":"jamboree","color":"ededed"},{"url":"https://api.github.com/repos/geneontology/go-ontology/labels/PomBase","name":"PomBase","color":"bfd4f2"},{"url":"https://api.github.com/repos/geneontology/go-ontology/labels/signaling","name":"signaling","color":"ededed"}],"state":"closed","locked":false,"assignee":{"login":"dosumis","id":112839,"avatar_url":"https://avatars.githubusercontent.com/u/112839?v=3","gravatar_id":"","url":"https://api.github.com/users/dosumis","html_url":"https://github.com/dosumis","followers_url":"https://api.github.com/users/dosumis/followers","following_url":"https://api.github.com/users/dosumis/following{/other_user}","gists_url":"https://api.github.com/users/dosumis/gists{/gist_id}","starred_url":"https://api.github.com/users/dosumis/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/dosumis/subscriptions","organizations_url":"https://api.github.com/users/dosumis/orgs","repos_url":"https://api.github.com/users/dosumis/repos","events_url":"https://api.github.com/users/dosumis/events{/privacy}","received_events_url":"https://api.github.com/users/dosumis/received_events","type":"User","site_admin":false},"milestone":null,"comments":11,"created_at":"2012-10-19T20:00:45Z","updated_at":"2016-02-18T09:39:31Z","closed_at":"2016-02-18T09:39:31Z","body":"I noticed that \r\nphopholipase C is mapped to \"signal transducer activity\" IEA using SPKW\r\n\r\nI reilised I'm not eexactly sure what the is term means:\r\n\r\nit is defined\r\nMolecular Function\r\nDefinition \tConveys a signal across a cell to trigger a change in cell function or state. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.\r\n\r\nDoes this mean \"across a cell\" or \"across  a membrane\" ?\r\n\r\nThe children all look like receptors so it seems to be across a cell membrane.\r\nHowever, GO:0004709\tMAP kinase kinase kinase activity has a parentage to \"signal transducer activity\"\r\n\r\nbut not MAP kinase, or MAP kinase kinase?\r\n\r\n\r\n\n\nReported by: ValWood\n\nOriginal Ticket: [geneontology/ontology-requests/9789](https://sourceforge.net/p/geneontology/ontology-requests/9789)"},"comment":{"url":"https://api.github.com/repos/geneontology/go-ontology/issues/comments/185628758","html_url":"https://github.com/geneontology/go-ontology/issues/9993#issuecomment-185628758","issue_url":"https://api.github.com/repos/geneontology/go-ontology/issues/9993","id":185628758,"user":{"login":"dosumis","id":112839,"avatar_url":"https://avatars.githubusercontent.com/u/112839?v=3","gravatar_id":"","url":"https://api.github.com/users/dosumis","html_url":"https://github.com/dosumis","followers_url":"https://api.github.com/users/dosumis/followers","following_url":"https://api.github.com/users/dosumis/following{/other_user}","gists_url":"https://api.github.com/users/dosumis/gists{/gist_id}","starred_url":"https://api.github.com/users/dosumis/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/dosumis/subscriptions","organizations_url":"https://api.github.com/users/dosumis/orgs","repos_url":"https://api.github.com/users/dosumis/repos","events_url":"https://api.github.com/users/dosumis/events{/privacy}","received_events_url":"https://api.github.com/users/dosumis/received_events","type":"User","site_admin":false},"created_at":"2016-02-18T09:39:31Z","updated_at":"2016-02-18T09:39:31Z","body":"Made equivalentTo: molecular_function that 'part of' some 'signal transduction'\r\n\r\nNow has MAPK activity etc.\r\n\r\nParent class 'molecular transducer activity' looks vague and hard to maintain, should probably obsolete.  Will add ticket on this to MF refactoring tracker."}}