{"action":"created","issue":{"url":"https://api.github.com/repos/dnanexus/viral-ngs/issues/49","repository_url":"https://api.github.com/repos/dnanexus/viral-ngs","labels_url":"https://api.github.com/repos/dnanexus/viral-ngs/issues/49/labels{/name}","comments_url":"https://api.github.com/repos/dnanexus/viral-ngs/issues/49/comments","events_url":"https://api.github.com/repos/dnanexus/viral-ngs/issues/49/events","html_url":"https://github.com/dnanexus/viral-ngs/issues/49","id":178663807,"number":49,"title":"demux jobs for hiseq lanes should get bigger instances","user":{"login":"dpark01","id":8513746,"avatar_url":"https://avatars.githubusercontent.com/u/8513746?v=3","gravatar_id":"","url":"https://api.github.com/users/dpark01","html_url":"https://github.com/dpark01","followers_url":"https://api.github.com/users/dpark01/followers","following_url":"https://api.github.com/users/dpark01/following{/other_user}","gists_url":"https://api.github.com/users/dpark01/gists{/gist_id}","starred_url":"https://api.github.com/users/dpark01/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/dpark01/subscriptions","organizations_url":"https://api.github.com/users/dpark01/orgs","repos_url":"https://api.github.com/users/dpark01/repos","events_url":"https://api.github.com/users/dpark01/events{/privacy}","received_events_url":"https://api.github.com/users/dpark01/received_events","type":"User","site_admin":false},"labels":[],"state":"open","locked":false,"assignee":null,"assignees":[],"milestone":null,"comments":4,"created_at":"2016-09-22T16:50:21Z","updated_at":"2016-10-20T13:12:51Z","closed_at":null,"body":"Looking at `job-BzVzv5j0jy12PPyv782QXZV3` it appears that hiseq lanes get dispatched on a mem1_ssd1_x4. In my own experience, I think we'd want a couple hundred GB of local instance storage at a minimum as well as at least 40-50GB RAM. I might suggest a mem3_ssd1_x8 or possibly a mem1_ssd2_x16 (if local storage is the limiting factor). Feel free to play with the associated flowcell of data as a test case."},"comment":{"url":"https://api.github.com/repos/dnanexus/viral-ngs/issues/comments/255101660","html_url":"https://github.com/dnanexus/viral-ngs/issues/49#issuecomment-255101660","issue_url":"https://api.github.com/repos/dnanexus/viral-ngs/issues/49","id":255101660,"user":{"login":"dpark01","id":8513746,"avatar_url":"https://avatars.githubusercontent.com/u/8513746?v=3","gravatar_id":"","url":"https://api.github.com/users/dpark01","html_url":"https://github.com/dpark01","followers_url":"https://api.github.com/users/dpark01/followers","following_url":"https://api.github.com/users/dpark01/following{/other_user}","gists_url":"https://api.github.com/users/dpark01/gists{/gist_id}","starred_url":"https://api.github.com/users/dpark01/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/dpark01/subscriptions","organizations_url":"https://api.github.com/users/dpark01/orgs","repos_url":"https://api.github.com/users/dpark01/repos","events_url":"https://api.github.com/users/dpark01/events{/privacy}","received_events_url":"https://api.github.com/users/dpark01/received_events","type":"User","site_admin":false},"created_at":"2016-10-20T13:12:51Z","updated_at":"2016-10-20T13:12:51Z","body":"Huh, looking at it, it seems you're right that demux memory usage seems actually quite minimal when the thread count is controlled. I wonder if runtime might benefit from more core count. Or LZ4 uploads instead of gzip."}}
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