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Preliminary indications\r\nwww.broadinstitute.org/~farjoun/Posters/estimating-independent-replicates.pdf ) show that in several experiments there seems to be a correlation between the alleles even when the\r\nUMI is different. This is highly non-intuitive and indicates that either experiments involving UMI's are harder to execute correclty than one would expect, or that writing code\r\nthat examines said UMI's is harder than expected...Either-way, I would be very happy if folks would collect some metrics on their favorite experiment with UMI and help me make this\r\na better tool that will QC UMI experiments well.\r\n\r\nThis is an alpha-class CLP. As you will see, there are many metrics, and I'm still not sure which of them are useful. 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