{"action":"created","issue":{"url":"https://api.github.com/repos/nipy/dipy/issues/1027","repository_url":"https://api.github.com/repos/nipy/dipy","labels_url":"https://api.github.com/repos/nipy/dipy/issues/1027/labels{/name}","comments_url":"https://api.github.com/repos/nipy/dipy/issues/1027/comments","events_url":"https://api.github.com/repos/nipy/dipy/issues/1027/events","html_url":"https://github.com/nipy/dipy/pull/1027","id":146018676,"number":1027,"title":"(WIP) NF: DKI microstructural model","user":{"login":"RafaelNH","id":5492638,"avatar_url":"https://avatars.githubusercontent.com/u/5492638?v=3","gravatar_id":"","url":"https://api.github.com/users/RafaelNH","html_url":"https://github.com/RafaelNH","followers_url":"https://api.github.com/users/RafaelNH/followers","following_url":"https://api.github.com/users/RafaelNH/following{/other_user}","gists_url":"https://api.github.com/users/RafaelNH/gists{/gist_id}","starred_url":"https://api.github.com/users/RafaelNH/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/RafaelNH/subscriptions","organizations_url":"https://api.github.com/users/RafaelNH/orgs","repos_url":"https://api.github.com/users/RafaelNH/repos","events_url":"https://api.github.com/users/RafaelNH/events{/privacy}","received_events_url":"https://api.github.com/users/RafaelNH/received_events","type":"User","site_admin":false},"labels":[],"state":"open","locked":false,"assignee":null,"milestone":null,"comments":2,"created_at":"2016-04-05T15:07:40Z","updated_at":"2016-04-05T23:01:26Z","closed_at":null,"pull_request":{"url":"https://api.github.com/repos/nipy/dipy/pulls/1027","html_url":"https://github.com/nipy/dipy/pull/1027","diff_url":"https://github.com/nipy/dipy/pull/1027.diff","patch_url":"https://github.com/nipy/dipy/pull/1027.patch"},"body":"Hello world! In this pull request, I am implementing the DKI based microstructural model which was suggested by ([Fieremans et al., 2011](http://www.ncbi.nlm.nih.gov/pubmed/21699989)).\r\n\r\nI am started this fresh PR from the work done on the last weeks of my participation at last years Google summer of code ([GSoC2015 blog](http://gsoc2015dipydki.blogspot.co.uk/)). At the moment, the axonal water fraction is already implemented. The next step is to estimate the intra and extra-axonal diffusion tensors.\r\n\r\nHope you enjoy!"},"comment":{"url":"https://api.github.com/repos/nipy/dipy/issues/comments/206026077","html_url":"https://github.com/nipy/dipy/pull/1027#issuecomment-206026077","issue_url":"https://api.github.com/repos/nipy/dipy/issues/1027","id":206026077,"user":{"login":"arokem","id":118582,"avatar_url":"https://avatars.githubusercontent.com/u/118582?v=3","gravatar_id":"","url":"https://api.github.com/users/arokem","html_url":"https://github.com/arokem","followers_url":"https://api.github.com/users/arokem/followers","following_url":"https://api.github.com/users/arokem/following{/other_user}","gists_url":"https://api.github.com/users/arokem/gists{/gist_id}","starred_url":"https://api.github.com/users/arokem/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/arokem/subscriptions","organizations_url":"https://api.github.com/users/arokem/orgs","repos_url":"https://api.github.com/users/arokem/repos","events_url":"https://api.github.com/users/arokem/events{/privacy}","received_events_url":"https://api.github.com/users/arokem/received_events","type":"User","site_admin":false},"created_at":"2016-04-05T23:01:26Z","updated_at":"2016-04-05T23:01:26Z","body":"Question: I just noticed that in some places, min_kurtosis is set per-default to 0 (e.g. here: https://github.com/nipy/dipy/blob/master/dipy/reconst/dki.py#L827) and in some places it is set to -1 (e.g. here: https://github.com/nipy/dipy/blob/master/dipy/reconst/dki.py#L363). Would it make sense to have the same default everywhere? What's a more reasonable default for these? Would kurtosis ever go below that of free water (0?)? "}}