{"action":"opened","issue":{"url":"https://api.github.com/repos/stschiff/msmc2/issues/5","repository_url":"https://api.github.com/repos/stschiff/msmc2","labels_url":"https://api.github.com/repos/stschiff/msmc2/issues/5/labels{/name}","comments_url":"https://api.github.com/repos/stschiff/msmc2/issues/5/comments","events_url":"https://api.github.com/repos/stschiff/msmc2/issues/5/events","html_url":"https://github.com/stschiff/msmc2/issues/5","id":176681208,"number":5,"title":"Multiple Chromosome Problems","user":{"login":"econdesousa","id":16939981,"avatar_url":"https://avatars.githubusercontent.com/u/16939981?v=3","gravatar_id":"","url":"https://api.github.com/users/econdesousa","html_url":"https://github.com/econdesousa","followers_url":"https://api.github.com/users/econdesousa/followers","following_url":"https://api.github.com/users/econdesousa/following{/other_user}","gists_url":"https://api.github.com/users/econdesousa/gists{/gist_id}","starred_url":"https://api.github.com/users/econdesousa/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/econdesousa/subscriptions","organizations_url":"https://api.github.com/users/econdesousa/orgs","repos_url":"https://api.github.com/users/econdesousa/repos","events_url":"https://api.github.com/users/econdesousa/events{/privacy}","received_events_url":"https://api.github.com/users/econdesousa/received_events","type":"User","site_admin":false},"labels":[],"state":"open","locked":false,"assignee":null,"assignees":[],"milestone":null,"comments":0,"created_at":"2016-09-13T15:59:47Z","updated_at":"2016-09-13T15:59:47Z","closed_at":null,"body":"Dear Doctor Schiffels \r\nFirst of all congratulations for the great work.\r\n\r\nI'm trying to apply your code for four individuals (2 of Population 1 and 2 of Population 2).\r\n\r\nIt all goes well when my data consists only in one chromosome, but when I try to use more (even for 2 chromosomes)  the code \"msmc2 -s -o outDIR/POP1.msmc2 -I 0,1,2,3 outDIR/Pop1Pop2.multihetsep.txt\" never passes the first \"Expectation step\". I believe, it is a memory problem.\r\n\r\nIs there any way to compute the msmc2 output for each chromosome separately and combine the results (only) at the end?\r\n\r\nThanks\r\n\r\nPS: the file outDIR/Pop1Pop2.multihetsep.txt was generated in two runs of generate_multihetsep.py (one for each chrom) and then concatenated.\r\n"}}
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