{"action":"created","issue":{"url":"https://api.github.com/repos/pombase/fypo/issues/2818","repository_url":"https://api.github.com/repos/pombase/fypo","labels_url":"https://api.github.com/repos/pombase/fypo/issues/2818/labels{/name}","comments_url":"https://api.github.com/repos/pombase/fypo/issues/2818/comments","events_url":"https://api.github.com/repos/pombase/fypo/issues/2818/events","html_url":"https://github.com/pombase/fypo/issues/2818","id":178075369,"number":2818,"title":"ntr: small vegetative cell with advanced mitosis and M phase arrest","user":{"login":"ValWood","id":7359272,"avatar_url":"https://avatars.githubusercontent.com/u/7359272?v=3","gravatar_id":"","url":"https://api.github.com/users/ValWood","html_url":"https://github.com/ValWood","followers_url":"https://api.github.com/users/ValWood/followers","following_url":"https://api.github.com/users/ValWood/following{/other_user}","gists_url":"https://api.github.com/users/ValWood/gists{/gist_id}","starred_url":"https://api.github.com/users/ValWood/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/ValWood/subscriptions","organizations_url":"https://api.github.com/users/ValWood/orgs","repos_url":"https://api.github.com/users/ValWood/repos","events_url":"https://api.github.com/users/ValWood/events{/privacy}","received_events_url":"https://api.github.com/users/ValWood/received_events","type":"User","site_admin":false},"labels":[],"state":"open","locked":false,"assignee":null,"assignees":[],"milestone":null,"comments":1,"created_at":"2016-09-20T14:25:37Z","updated_at":"2016-09-20T16:51:21Z","closed_at":null,"body":"\r\nThis term is analogous to\r\nthe inviable elongated cell with mitotic transition delay and cell cycle arrest in M-phase\r\n\r\n it will be  a child of both\r\nFYPO:0001046\tpremature mitosis\r\nand\r\nFYPO:0000648\tviable small vegetative cell\r\nwhich are often concurrently annotated (see comment)\r\n\r\nThis more precise phenotype will be useful. IIRC we could not put  FYPO:0000648\tviable small vegetative cell as an output or  FYPO:0001046\tpremature mitosis because cells can be small also if entering G0 or grown on non-rich media?\r\n\r\n"},"comment":{"url":"https://api.github.com/repos/pombase/fypo/issues/comments/248361738","html_url":"https://github.com/pombase/fypo/issues/2818#issuecomment-248361738","issue_url":"https://api.github.com/repos/pombase/fypo/issues/2818","id":248361738,"user":{"login":"mah11","id":5196259,"avatar_url":"https://avatars.githubusercontent.com/u/5196259?v=3","gravatar_id":"","url":"https://api.github.com/users/mah11","html_url":"https://github.com/mah11","followers_url":"https://api.github.com/users/mah11/followers","following_url":"https://api.github.com/users/mah11/following{/other_user}","gists_url":"https://api.github.com/users/mah11/gists{/gist_id}","starred_url":"https://api.github.com/users/mah11/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/mah11/subscriptions","organizations_url":"https://api.github.com/users/mah11/orgs","repos_url":"https://api.github.com/users/mah11/repos","events_url":"https://api.github.com/users/mah11/events{/privacy}","received_events_url":"https://api.github.com/users/mah11/received_events","type":"User","site_admin":false},"created_at":"2016-09-20T16:51:21Z","updated_at":"2016-09-20T16:51:21Z","body":"> IIRC we could not put FYPO:0000648 viable small vegetative cell as an output [of] FYPO:0001046 premature mitosis because cells can be small also if entering G0 or grown on non-rich media?\r\n\r\nNo, smallness, like everything else, is defined relative to wild type under the same conditions.\r\n\r\nAs noted in #2544, we haven't linked FYPO:0000648 to FYPO:0001046 because we're waiting for you and Jacky to figure out whether there's any way to define premature mitosis using criteria other than cell size, or any way to get a small cell other than by premature mitosis.\r\n\r\nWe'll need to know that for this ticket, too, to tell whether the new term will simply be \"small vegetative cell with cell cycle arrest in M phase\" or if the \"premature mitosis\" part actually adds any further distinction.\r\n\r\nThere's more background in an older ticket in SourceForge (one of the few that missed out on the move to GitHub) - https://sourceforge.net/p/pombase/fission-yeast-phenotype/1770/"}}
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