{"action":"created","issue":{"url":"https://api.github.com/repos/geneontology/go-ontology/issues/12636","repository_url":"https://api.github.com/repos/geneontology/go-ontology","labels_url":"https://api.github.com/repos/geneontology/go-ontology/issues/12636/labels{/name}","comments_url":"https://api.github.com/repos/geneontology/go-ontology/issues/12636/comments","events_url":"https://api.github.com/repos/geneontology/go-ontology/issues/12636/events","html_url":"https://github.com/geneontology/go-ontology/issues/12636","id":175086613,"number":12636,"title":"CVT pathway taxon restriction","user":{"login":"ValWood","id":7359272,"avatar_url":"https://avatars.githubusercontent.com/u/7359272?v=3","gravatar_id":"","url":"https://api.github.com/users/ValWood","html_url":"https://github.com/ValWood","followers_url":"https://api.github.com/users/ValWood/followers","following_url":"https://api.github.com/users/ValWood/following{/other_user}","gists_url":"https://api.github.com/users/ValWood/gists{/gist_id}","starred_url":"https://api.github.com/users/ValWood/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/ValWood/subscriptions","organizations_url":"https://api.github.com/users/ValWood/orgs","repos_url":"https://api.github.com/users/ValWood/repos","events_url":"https://api.github.com/users/ValWood/events{/privacy}","received_events_url":"https://api.github.com/users/ValWood/received_events","type":"User","site_admin":false},"labels":[{"url":"https://api.github.com/repos/geneontology/go-ontology/labels/PomBase","name":"PomBase","color":"bfd4f2"}],"state":"open","locked":false,"assignee":null,"assignees":[],"milestone":null,"comments":1,"created_at":"2016-09-05T14:49:27Z","updated_at":"2016-09-06T13:16:04Z","closed_at":null,"body":"CVT pathway is\r\n\r\nA constitutive biosynthetic process that occurs under nutrient-rich conditions, in which two resident vacuolar hydrolases, aminopeptidase I and alpha-mannosidase, are sequestered into vesicles; these vesicles are transported to, and then fuse with, the vacuole. This pathway is mostly observed in yeast. \r\n\r\nThis is a specific pathway obeserved in S. cerevisiae. I don't know how broad it is, but it isn't present in fission yeast where  cytoplasmic to vacuole targeting does not occur in nutrient rich conditions.\r\n\r\n\r\n(most cytoplasm to vacuole transport in via secretory pathway)\r\n\r\n\r\n\r\n"},"comment":{"url":"https://api.github.com/repos/geneontology/go-ontology/issues/comments/244946243","html_url":"https://github.com/geneontology/go-ontology/issues/12636#issuecomment-244946243","issue_url":"https://api.github.com/repos/geneontology/go-ontology/issues/12636","id":244946243,"user":{"login":"ukemi","id":11067494,"avatar_url":"https://avatars.githubusercontent.com/u/11067494?v=3","gravatar_id":"","url":"https://api.github.com/users/ukemi","html_url":"https://github.com/ukemi","followers_url":"https://api.github.com/users/ukemi/followers","following_url":"https://api.github.com/users/ukemi/following{/other_user}","gists_url":"https://api.github.com/users/ukemi/gists{/gist_id}","starred_url":"https://api.github.com/users/ukemi/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/ukemi/subscriptions","organizations_url":"https://api.github.com/users/ukemi/orgs","repos_url":"https://api.github.com/users/ukemi/repos","events_url":"https://api.github.com/users/ukemi/events{/privacy}","received_events_url":"https://api.github.com/users/ukemi/received_events","type":"User","site_admin":false},"created_at":"2016-09-06T13:16:04Z","updated_at":"2016-09-06T13:16:04Z","body":"So never in Pombe?"}}
{"actor":{"display_login":"ukemi"}}