{"action":"created","issue":{"url":"https://api.github.com/repos/The-Sequence-Ontology/SO-Ontologies/issues/368","repository_url":"https://api.github.com/repos/The-Sequence-Ontology/SO-Ontologies","labels_url":"https://api.github.com/repos/The-Sequence-Ontology/SO-Ontologies/issues/368/labels{/name}","comments_url":"https://api.github.com/repos/The-Sequence-Ontology/SO-Ontologies/issues/368/comments","events_url":"https://api.github.com/repos/The-Sequence-Ontology/SO-Ontologies/issues/368/events","html_url":"https://github.com/The-Sequence-Ontology/SO-Ontologies/issues/368","id":170223887,"number":368,"title":"Add 'regulatory uORF' synonym to SO:0002027","user":{"login":"catherinefarrell","id":20645718,"avatar_url":"https://avatars.githubusercontent.com/u/20645718?v=3","gravatar_id":"","url":"https://api.github.com/users/catherinefarrell","html_url":"https://github.com/catherinefarrell","followers_url":"https://api.github.com/users/catherinefarrell/followers","following_url":"https://api.github.com/users/catherinefarrell/following{/other_user}","gists_url":"https://api.github.com/users/catherinefarrell/gists{/gist_id}","starred_url":"https://api.github.com/users/catherinefarrell/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/catherinefarrell/subscriptions","organizations_url":"https://api.github.com/users/catherinefarrell/orgs","repos_url":"https://api.github.com/users/catherinefarrell/repos","events_url":"https://api.github.com/users/catherinefarrell/events{/privacy}","received_events_url":"https://api.github.com/users/catherinefarrell/received_events","type":"User","site_admin":false},"labels":[],"state":"open","locked":false,"assignee":null,"assignees":[],"milestone":null,"comments":3,"created_at":"2016-08-09T17:26:20Z","updated_at":"2016-08-13T01:44:55Z","closed_at":null,"body":"RefSeq is annotating regulatory uORFs on mRNAs when there is experimental evidence in the literature for a particular uORF being regulatory to pORF translation, e.g., NM_000671.4 misc_features at 24..86 and 54..86. We want to better format the /note qualifier on these features with a controlled vocabulary string that matches an SO string or an associated synonym. SO:0002027 ('uORF' primary string and 'upstream ORF' synonym) is the appropriate entry and the definition fits our use, but we want to include the word \"regulatory\" in our feature to help distinguish these uORFs from the many other uORFs present in mRNAs that don't have a known regulatory function.\r\n\r\nSince we prefer to have our controlled vocabularies matching either an SO primary term or synonym, can you add 'regulatory uORF' as a synonym to SO:0002027?\r\n\r\nThanks for your help!\r\n\r\nCatherine Farrell, Ph.D\r\nStaff Scientist - RefSeq Project\r\nNCBI/NLM/NIH"},"comment":{"url":"https://api.github.com/repos/The-Sequence-Ontology/SO-Ontologies/issues/comments/239594851","html_url":"https://github.com/The-Sequence-Ontology/SO-Ontologies/issues/368#issuecomment-239594851","issue_url":"https://api.github.com/repos/The-Sequence-Ontology/SO-Ontologies/issues/368","id":239594851,"user":{"login":"theintuitivesoul","id":20880750,"avatar_url":"https://avatars.githubusercontent.com/u/20880750?v=3","gravatar_id":"","url":"https://api.github.com/users/theintuitivesoul","html_url":"https://github.com/theintuitivesoul","followers_url":"https://api.github.com/users/theintuitivesoul/followers","following_url":"https://api.github.com/users/theintuitivesoul/following{/other_user}","gists_url":"https://api.github.com/users/theintuitivesoul/gists{/gist_id}","starred_url":"https://api.github.com/users/theintuitivesoul/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/theintuitivesoul/subscriptions","organizations_url":"https://api.github.com/users/theintuitivesoul/orgs","repos_url":"https://api.github.com/users/theintuitivesoul/repos","events_url":"https://api.github.com/users/theintuitivesoul/events{/privacy}","received_events_url":"https://api.github.com/users/theintuitivesoul/received_events","type":"User","site_admin":false},"created_at":"2016-08-13T01:44:55Z","updated_at":"2016-08-13T01:44:55Z","body":"I was not sure but I got in touch with 23&Me. I didn't know if it was something I did or if I did."}}
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