{"action":"created","issue":{"url":"https://api.github.com/repos/pombase/fypo/issues/2562","repository_url":"https://api.github.com/repos/pombase/fypo","labels_url":"https://api.github.com/repos/pombase/fypo/issues/2562/labels{/name}","comments_url":"https://api.github.com/repos/pombase/fypo/issues/2562/comments","events_url":"https://api.github.com/repos/pombase/fypo/issues/2562/events","html_url":"https://github.com/pombase/fypo/issues/2562","id":137411528,"number":2562,"title":"early mitosis ","user":{"login":"Antonialock","id":12727506,"avatar_url":"https://avatars.githubusercontent.com/u/12727506?v=3","gravatar_id":"","url":"https://api.github.com/users/Antonialock","html_url":"https://github.com/Antonialock","followers_url":"https://api.github.com/users/Antonialock/followers","following_url":"https://api.github.com/users/Antonialock/following{/other_user}","gists_url":"https://api.github.com/users/Antonialock/gists{/gist_id}","starred_url":"https://api.github.com/users/Antonialock/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/Antonialock/subscriptions","organizations_url":"https://api.github.com/users/Antonialock/orgs","repos_url":"https://api.github.com/users/Antonialock/repos","events_url":"https://api.github.com/users/Antonialock/events{/privacy}","received_events_url":"https://api.github.com/users/Antonialock/received_events","type":"User","site_admin":false},"labels":[],"state":"open","locked":false,"assignee":null,"milestone":null,"comments":18,"created_at":"2016-02-29T23:24:27Z","updated_at":"2016-03-01T10:20:53Z","closed_at":null,"body":"**Q1: are these the same thing?**\r\n\r\npremature mitotic G2/M transition \r\nA cell cycle phenotype in which the G2/M transition of the mitotic cell cycle begins earlier than normal. The duration of G2 phase is thus shorter than normal.\r\n\r\npremature mitosis \r\nA cellular process phenotype in which cells enter mitosis earlier, relative to cell size or DNA integrity checkpoint status, than normal.\r\n\r\n**Q2. Should one or both lead to**\r\nmitotic catastrophe\r\nAn inviable phenotype in which a cell enters mitosis prematurely, undergoes abnormal mitotic chromosome segregation, and subsequently dies."},"comment":{"url":"https://api.github.com/repos/pombase/fypo/issues/comments/190650880","html_url":"https://github.com/pombase/fypo/issues/2562#issuecomment-190650880","issue_url":"https://api.github.com/repos/pombase/fypo/issues/2562","id":190650880,"user":{"login":"ValWood","id":7359272,"avatar_url":"https://avatars.githubusercontent.com/u/7359272?v=3","gravatar_id":"","url":"https://api.github.com/users/ValWood","html_url":"https://github.com/ValWood","followers_url":"https://api.github.com/users/ValWood/followers","following_url":"https://api.github.com/users/ValWood/following{/other_user}","gists_url":"https://api.github.com/users/ValWood/gists{/gist_id}","starred_url":"https://api.github.com/users/ValWood/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/ValWood/subscriptions","organizations_url":"https://api.github.com/users/ValWood/orgs","repos_url":"https://api.github.com/users/ValWood/repos","events_url":"https://api.github.com/users/ValWood/events{/privacy}","received_events_url":"https://api.github.com/users/ValWood/received_events","type":"User","site_admin":false},"created_at":"2016-03-01T10:20:53Z","updated_at":"2016-03-01T10:20:53Z","body":"- Presumably an event (some stress?) could inhibit atf1, thereby delaying G2/M?\r\n\r\nYes, thats true but it hasn't been demonstrated."}}