{"action":"closed","issue":{"url":"https://api.github.com/repos/DiseaseOntology/HumanDiseaseOntology/issues/182","repository_url":"https://api.github.com/repos/DiseaseOntology/HumanDiseaseOntology","labels_url":"https://api.github.com/repos/DiseaseOntology/HumanDiseaseOntology/issues/182/labels{/name}","comments_url":"https://api.github.com/repos/DiseaseOntology/HumanDiseaseOntology/issues/182/comments","events_url":"https://api.github.com/repos/DiseaseOntology/HumanDiseaseOntology/issues/182/events","html_url":"https://github.com/DiseaseOntology/HumanDiseaseOntology/issues/182","id":177031124,"number":182,"title":"Costello syndrome definition","user":{"login":"cerivs","id":2602957,"avatar_url":"https://avatars.githubusercontent.com/u/2602957?v=3","gravatar_id":"","url":"https://api.github.com/users/cerivs","html_url":"https://github.com/cerivs","followers_url":"https://api.github.com/users/cerivs/followers","following_url":"https://api.github.com/users/cerivs/following{/other_user}","gists_url":"https://api.github.com/users/cerivs/gists{/gist_id}","starred_url":"https://api.github.com/users/cerivs/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/cerivs/subscriptions","organizations_url":"https://api.github.com/users/cerivs/orgs","repos_url":"https://api.github.com/users/cerivs/repos","events_url":"https://api.github.com/users/cerivs/events{/privacy}","received_events_url":"https://api.github.com/users/cerivs/received_events","type":"User","site_admin":false},"labels":[],"state":"closed","locked":false,"assignee":null,"assignees":[],"milestone":null,"comments":0,"created_at":"2016-09-14T21:50:50Z","updated_at":"2016-09-16T19:19:02Z","closed_at":"2016-09-16T19:19:02Z","body":"A syndrome characterized by craniofacial dysmorphology, cardiac defects, mild mental retardation, and high birth weight followed by a failure to thrive and developmental delays. These patients also have a tendency to develop multiple papillomas and various types of cancer, mainly rhabdomyosarcomas, neuroblastomas. \r\n\r\nReferences:  PMID:907573,  PMID:17250658\r\nCostello, 1977 & Review Rauen, 2007"}}
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