{"action":"created","issue":{"url":"https://api.github.com/repos/geneontology/go-ontology/issues/12264","repository_url":"https://api.github.com/repos/geneontology/go-ontology","labels_url":"https://api.github.com/repos/geneontology/go-ontology/issues/12264/labels{/name}","comments_url":"https://api.github.com/repos/geneontology/go-ontology/issues/12264/comments","events_url":"https://api.github.com/repos/geneontology/go-ontology/issues/12264/events","html_url":"https://github.com/geneontology/go-ontology/issues/12264","id":131620438,"number":12264,"title":"endosome to lysosome transport","user":{"login":"bmeldal","id":10517124,"avatar_url":"https://avatars.githubusercontent.com/u/10517124?v=3","gravatar_id":"","url":"https://api.github.com/users/bmeldal","html_url":"https://github.com/bmeldal","followers_url":"https://api.github.com/users/bmeldal/followers","following_url":"https://api.github.com/users/bmeldal/following{/other_user}","gists_url":"https://api.github.com/users/bmeldal/gists{/gist_id}","starred_url":"https://api.github.com/users/bmeldal/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/bmeldal/subscriptions","organizations_url":"https://api.github.com/users/bmeldal/orgs","repos_url":"https://api.github.com/users/bmeldal/repos","events_url":"https://api.github.com/users/bmeldal/events{/privacy}","received_events_url":"https://api.github.com/users/bmeldal/received_events","type":"User","site_admin":false},"labels":[{"url":"https://api.github.com/repos/geneontology/go-ontology/labels/Other%20term-related%20request","name":"Other term-related request","color":"bfe5bf"}],"state":"open","locked":false,"assignee":{"login":"ukemi","id":11067494,"avatar_url":"https://avatars.githubusercontent.com/u/11067494?v=3","gravatar_id":"","url":"https://api.github.com/users/ukemi","html_url":"https://github.com/ukemi","followers_url":"https://api.github.com/users/ukemi/followers","following_url":"https://api.github.com/users/ukemi/following{/other_user}","gists_url":"https://api.github.com/users/ukemi/gists{/gist_id}","starred_url":"https://api.github.com/users/ukemi/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/ukemi/subscriptions","organizations_url":"https://api.github.com/users/ukemi/orgs","repos_url":"https://api.github.com/users/ukemi/repos","events_url":"https://api.github.com/users/ukemi/events{/privacy}","received_events_url":"https://api.github.com/users/ukemi/received_events","type":"User","site_admin":false},"assignees":[{"login":"ukemi","id":11067494,"avatar_url":"https://avatars.githubusercontent.com/u/11067494?v=3","gravatar_id":"","url":"https://api.github.com/users/ukemi","html_url":"https://github.com/ukemi","followers_url":"https://api.github.com/users/ukemi/followers","following_url":"https://api.github.com/users/ukemi/following{/other_user}","gists_url":"https://api.github.com/users/ukemi/gists{/gist_id}","starred_url":"https://api.github.com/users/ukemi/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/ukemi/subscriptions","organizations_url":"https://api.github.com/users/ukemi/orgs","repos_url":"https://api.github.com/users/ukemi/repos","events_url":"https://api.github.com/users/ukemi/events{/privacy}","received_events_url":"https://api.github.com/users/ukemi/received_events","type":"User","site_admin":false}],"milestone":null,"comments":28,"created_at":"2016-02-05T11:36:23Z","updated_at":"2016-08-01T13:42:54Z","closed_at":null,"body":"Hi,\r\n\r\nI'm trying to figure out which process terms are appropriate for VPS4 complexes which acts on the membrane fission of multivesicular bodies (MVBs), autophasosomes and lysosomes as well as plasma membrane fission at cytokinesis, viral budding and nuclear membrane fission.\r\n\r\n1)\r\nWhy has the endosome not got a link to vacuole? The defs do not indicate a reason. \r\nWe already have:\r\nautolysosome is_a lysosome \r\nlysosome is_a vacuole \r\namphisome is_a autophagosomes \r\nautophagosomes is_a vacuole \r\nAll of these compartments can derive elements from the endosome which is also a membrane-enclosed, liquid-containing compartment.\r\nAlso:\r\nmultivesicular body is_a endosome\r\nIn fact, it's a late endosome, that link is also missing.\r\nAI 1: \r\nreplace multivesicular body is_a endosome\r\nwith\r\nmultivesicular body is_a late endosome\r\n\r\nAI 2:\r\nAdd endosomal transport is_a vacuolar transport?\r\n\r\n2)\r\nI need a new process:\r\nGO:NEW late endosome to lysosome transport via multivesicular body sorting pathway\r\nis_a GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway\r\nis_a GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway\r\nis_a GO:1902774 late endosome to lysosome transport\r\n\r\nI don't know if there is a template as I need the \"via\" bit to distinguish it from GO:1902774 late endosome to lysosome transport\r\n\r\n3)\r\nI also think\r\nGO:0032510 endosome to lysosome transport via multivesicular body sorting pathway\r\nshould be is_a GO:0008333 endosome to lysosome transport\r\n\r\nThanks,\r\nBirgit"},"comment":{"url":"https://api.github.com/repos/geneontology/go-ontology/issues/comments/236583765","html_url":"https://github.com/geneontology/go-ontology/issues/12264#issuecomment-236583765","issue_url":"https://api.github.com/repos/geneontology/go-ontology/issues/12264","id":236583765,"user":{"login":"dosumis","id":112839,"avatar_url":"https://avatars.githubusercontent.com/u/112839?v=3","gravatar_id":"","url":"https://api.github.com/users/dosumis","html_url":"https://github.com/dosumis","followers_url":"https://api.github.com/users/dosumis/followers","following_url":"https://api.github.com/users/dosumis/following{/other_user}","gists_url":"https://api.github.com/users/dosumis/gists{/gist_id}","starred_url":"https://api.github.com/users/dosumis/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/dosumis/subscriptions","organizations_url":"https://api.github.com/users/dosumis/orgs","repos_url":"https://api.github.com/users/dosumis/repos","events_url":"https://api.github.com/users/dosumis/events{/privacy}","received_events_url":"https://api.github.com/users/dosumis/received_events","type":"User","site_admin":false},"created_at":"2016-08-01T13:42:54Z","updated_at":"2016-08-01T13:42:54Z","body":"Should be an membrane bound organelle at least.\n\nOn 1 Aug 2016, at 22:32, David Hill <notifications@github.com> wrote:\n\n> So is the solution to move endosome out from under vacuole and back to membrane bound vesicle?\n> \n> -D\n> \n> —\n> You are receiving this because you were mentioned.\n> Reply to this email directly, view it on GitHub, or mute the thread.\n> \n\n"}}
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