{"action":"created","issue":{"url":"https://api.github.com/repos/geneontology/go-ontology/issues/12359","repository_url":"https://api.github.com/repos/geneontology/go-ontology","labels_url":"https://api.github.com/repos/geneontology/go-ontology/issues/12359/labels{/name}","comments_url":"https://api.github.com/repos/geneontology/go-ontology/issues/12359/comments","events_url":"https://api.github.com/repos/geneontology/go-ontology/issues/12359/events","html_url":"https://github.com/geneontology/go-ontology/issues/12359","id":142953143,"number":12359,"title":"Definition qualification for EMT","user":{"login":"RLovering","id":12080010,"avatar_url":"https://avatars.githubusercontent.com/u/12080010?v=3","gravatar_id":"","url":"https://api.github.com/users/RLovering","html_url":"https://github.com/RLovering","followers_url":"https://api.github.com/users/RLovering/followers","following_url":"https://api.github.com/users/RLovering/following{/other_user}","gists_url":"https://api.github.com/users/RLovering/gists{/gist_id}","starred_url":"https://api.github.com/users/RLovering/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/RLovering/subscriptions","organizations_url":"https://api.github.com/users/RLovering/orgs","repos_url":"https://api.github.com/users/RLovering/repos","events_url":"https://api.github.com/users/RLovering/events{/privacy}","received_events_url":"https://api.github.com/users/RLovering/received_events","type":"User","site_admin":false},"labels":[{"url":"https://api.github.com/repos/geneontology/go-ontology/labels/BHF-UCL","name":"BHF-UCL","color":"bfd4f2"},{"url":"https://api.github.com/repos/geneontology/go-ontology/labels/Other%20term-related%20request","name":"Other term-related request","color":"bfe5bf"},{"url":"https://api.github.com/repos/geneontology/go-ontology/labels/quick%20fix","name":"quick fix","color":"d4c5f9"},{"url":"https://api.github.com/repos/geneontology/go-ontology/labels/signaling","name":"signaling","color":"ededed"}],"state":"open","locked":false,"assignee":{"login":"ukemi","id":11067494,"avatar_url":"https://avatars.githubusercontent.com/u/11067494?v=3","gravatar_id":"","url":"https://api.github.com/users/ukemi","html_url":"https://github.com/ukemi","followers_url":"https://api.github.com/users/ukemi/followers","following_url":"https://api.github.com/users/ukemi/following{/other_user}","gists_url":"https://api.github.com/users/ukemi/gists{/gist_id}","starred_url":"https://api.github.com/users/ukemi/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/ukemi/subscriptions","organizations_url":"https://api.github.com/users/ukemi/orgs","repos_url":"https://api.github.com/users/ukemi/repos","events_url":"https://api.github.com/users/ukemi/events{/privacy}","received_events_url":"https://api.github.com/users/ukemi/received_events","type":"User","site_admin":false},"milestone":null,"comments":4,"created_at":"2016-03-23T13:00:05Z","updated_at":"2016-03-23T19:32:07Z","closed_at":null,"body":"Hi\r\n\r\nPlease could you clarify what exactly should be annotated with the GO term \r\nGO:0001837 epithelial to mesenchymal transition\r\nDefinition: A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.\r\nShould the proteins involved in the signalling pathways that lead to EMT be included or would these be regulating EMT (i.e. casually upstream of EMT). To date it has been associated with the signalling pathway proteins.\r\n\r\nIf this is the case please could you add something in the definition to clarify this\r\n\r\nThanks\r\n\r\nRuth"},"comment":{"url":"https://api.github.com/repos/geneontology/go-ontology/issues/comments/200508830","html_url":"https://github.com/geneontology/go-ontology/issues/12359#issuecomment-200508830","issue_url":"https://api.github.com/repos/geneontology/go-ontology/issues/12359","id":200508830,"user":{"login":"RLovering","id":12080010,"avatar_url":"https://avatars.githubusercontent.com/u/12080010?v=3","gravatar_id":"","url":"https://api.github.com/users/RLovering","html_url":"https://github.com/RLovering","followers_url":"https://api.github.com/users/RLovering/followers","following_url":"https://api.github.com/users/RLovering/following{/other_user}","gists_url":"https://api.github.com/users/RLovering/gists{/gist_id}","starred_url":"https://api.github.com/users/RLovering/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/RLovering/subscriptions","organizations_url":"https://api.github.com/users/RLovering/orgs","repos_url":"https://api.github.com/users/RLovering/repos","events_url":"https://api.github.com/users/RLovering/events{/privacy}","received_events_url":"https://api.github.com/users/RLovering/received_events","type":"User","site_admin":false},"created_at":"2016-03-23T19:32:07Z","updated_at":"2016-03-23T19:32:07Z","body":"I think a comment would be helpful. I always assume that signaling pathways are included in 'xx_development' terms because the 'process' is complex. So it would be good to clarify that this describes the event following signalling.\r\n\r\nRuth"}}