oxogestone phenpropionate oxogestone phenpropionate oxogestone phenpropionate (opp; usan) (former developmental code name or tentative brand name oxageston), also known as xinogestone, as well as 20β-hydroxy-19-norprogesterone 20β-(3-phenylpropionate), is a progestin related to the 19-norprogesterone derivatives which was developed as an injectable hormonal contraceptive, specifically a progestogen-only injectable contraceptive, in the 1960s and early 1970s but was never marketed. it was studied at a dose of 50 to 75 mg once a month by intramuscular injection but was associated with a high failure rate with this regimen and was not further developed. opp is the 20β-(3-phenylpropionate) ester of oxogestone, which, similarly, was never marketed. parenteral potencies and durations of progestogens compound form dose for specific uses (mg) doa tfd poicd cicd algestone acetophenideoil soln.-–75–15014–32 d gestonorone caproateoil soln.25–50––8–13 d hydroxyprogest. acetateaq. susp.350––9–16 d hydroxyprogest. caproateoil soln.250–500–250–5005–21 d medroxyprog. acetateaq. susp.50–1001502514–50+ d megestrol acetateaq. susp.-–25>14 d norethisterone enanthateoil soln.100–2002005011–52 d progesteroneoil soln.200––2–6 d aq. soln. ?––1–2 d aq. susp.50–200––7–14 d notes and sources: sources: all given by intramuscular or subcutaneous injection. progesterone production during the luteal phase is ~25 (15–50) mg/day. the oid of ohpc is 250 to 500 mg/month. duration of action in days. usually given for 14 days. usually dosed every two to three months. usually dosed once monthly. never marketed or approved by this route. in divided doses (2 × 125 or 250 mg for ohpc, 10 × 20 mg for p4). oxogestone phenpropionateclinical dataother namesoxogesterone phenpropionate; xinogestone; oxageston; 20β-hydroxy-19-norprogesterone phenylpropionate; 20β-dihydro-19-norprogesterone 20β-(3-phenylpropionate); 20β-hydroxy-19-norpregn-4-en-3-one 20β-(3-phenylpropionate); (20r)-3-oxo-19-norpregn-4-en-20-yl 3-phenylpropanoateroutes ofadministrationintramuscular injectiondrug classprogestogen; progestogen esteridentifiers iupac name phenanthren-17-yl]ethyl] 3-phenylpropanoate cas number16915-80-3pubchem cid20055360chemspider16736681unii7ia4j676hmkeggd05308chemblchembl2107303comptox dashboard (epa)dtxsid20937602 chemical and physical dataformulac29h38o3molar mass434.620 g·mol−13d model (jsmol)interactive image smiles cc(c1ccc2c1(ccc3c2ccc4=cc(=o)ccc34)c)oc(=o)ccc5=cc=cc=c5 inchi inchi=1s/c29h38o3/c1-19(32-28(31)15-8-20-6-4-3-5-7-20)26-13-14-27-25-11-9-21-18-22(30)10-12-23(21)24(25)16-17-29(26,27)2/h3-7,18-19,23-27h,8-17h2,1-2h3/t19-,23+,24-,25-,26-,27+,29-/m1/s1key:lhpbufxeiolurh-gqzonrfdsa-n