5f-cumyl-pinaca 5f-cumyl-pinaca 5f-cumyl-pinaca (also known as sgt-25 and sometimes sold in e-cigarette form as c-liquid) is an indazole-3-carboxamide based synthetic cannabinoid. 5f-cumyl-pinaca acts as a potent agonist for the cannabinoid receptors, with the original patent claiming approximately 4x selectivity for cb1, having an ec50 of <0.1 nm for human cb1 receptors and 0.37 nm for human cb2 receptors. in more recent assays using different techniques, 5f-cumyl-pinaca was variously found to have an ec50 of 0.43 nm at cb1 and 11.3 nm at cb2, suggesting a somewhat higher cb1 selectivity of 26 times, or alternatively 15.1 nm at cb1 and 34.8 nm at cb2 with only 2.3 times selectivity, however these figures cannot be directly compared due to the different assay techniques used in each case. 5f-cumyl-pinacalegal statuslegal status ca: schedule ii de: npsg (industrial and scientific use only) uk: under psychoactive substances act us: schedule i illegal in sweden identifiers iupac name 1-(5-fluoropentyl)-n-(2-phenylpropan-2-yl)-1h-indazole-3-carboxamide cas number1400742-16-6 ypubchem cid86274158chemspider35228406uniie827uuv3s9chemical and physical dataformulac22h26fn3omolar mass367.468 g·mol−13d model (jsmol)interactive image smiles o=c(nc(c)(c)c1=cc=cc=c1)c2=nn(cccccf)c3=c2c=cc=c3 inchi inchi=1s/c22h26fn3o/c1-22(2,17-11-5-3-6-12-17)24-21(27)20-18-13-7-8-14-19(18)26(25-20)16-10-4-9-15-23/h3,5-8,11-14h,4,9-10,15-16h2,1-2h3,(h,24,27)key:xshgviphmotdcs-uhfffaoysa-n legal status in the united states, 5f-cumyl-pinaca was temporarily emergency scheduled by the dea in 2019. and made a permanent schedule i controlled substance on april 7, 2022. sweden's public health agency suggested classifying 5f-cumyl-pinaca as a hazardous substance on november 10, 2014.