surprised by the notion that cannabis can induce symptoms of nausea and vomiting, given the fact that cannabis is used to prevent nausea and vomiting. the portmanteau "scromiting" (scream + vomiting) has been used as a colloquial name for the condition, though it is not clear how widespread the use of the term is. research directions it is unclear why chs is disproportionately uncommon in recognition of how widely used cannabis is throughout the world. there may be genetic differences between cannabis users that affect one's risk for developing chs, e.g., a genetic difference affecting cannabinoid metabolism that increases the level of pro-emetic cannabinoids. the pathophysiology of the syndrome is also unclear, especially with regards to the effect of cannabinoids on the gut. the long-term outcomes of patients that have had chs are unknown.