ly-379,268 ly-379,268 ly-379,268 is a drug that is used in neuroscience research, which acts as a potent and selective agonist for the group ii metabotropic glutamate receptors (mglur2/3). ly-379,268identifiers iupac name (1s,2r,5r,6r)-2-amino-4-oxabicyclohexane-2,6-dicarboxylic acid cas number191471-52-0 ypubchem cid10197984chemspider8373484 nuniis96jf4j697chebichebi:192545comptox dashboard (epa)dtxsid90436637 chemical and physical dataformulac7h9no5molar mass187.151 g·mol−13d model (jsmol)interactive image smiles c1(2(2o1)c(=o)o)(c(=o)o)n inchi inchi=1s/c7h9no5/c8-7(6(11)12)1-13-4-2(3(4)7)5(9)10/h2-4h,1,8h2,(h,9,10)(h,11,12)/t2-,3-,4+,7+/m1/s1 nkey:yasvrzwvugjelu-mdasverjsa-n n ny (what is this?) (verify) it is derived from the older mglur group ii agonist eglumegad, and led on to the development of the more potent compound ly-404,039, but is still widely used in research itself. ly-379,268 has sedative, neuroprotective, anti-addictive and anticonvulsant effects in animals, and blocks the effects of pcp and doi, which has led to research into ly-379,268 and similar compounds as antipsychotic drugs for the treatment of schizophrenia in animals. there are inconsistent findings about an additional activity as a dopamine d2 receptor partial agonist.