mycoplasmataceae mycoplasmataceae mycoplasmataceae is a family of bacteria in the order mycoplasmatales. this family consists of the genera mycoplasma and ureaplasma. mycoplasmataceae scientific classification domain: bacteria phylum: mycoplasmatota class: mollicutes order: mycoplasmatalesfreundt, 1955 family: mycoplasmataceaefreundt, 1955 genera "ca. hepatoplasma" mycoplasma ureaplasma "ca. vermiplasma" williamsoniiplasma synonyms "borrelomycetaceae" turner 1935 "haemobartonellaceae" yanokov 1973 "parasitaceae" sabin 1941 "pleuropneumoniaceae" tulasne & brisou 1955 in 1967, the order mycoplasmatales was incorporated into the class mollicutes. many species are sexually transmitted and cause pelvic inflammatory disease. taxonomy mycoplasma main article: mycoplasma mycoplasma refers to a genus of bacteria that lack a cell wall and possess a three-layered cellular membrane. they can be parasitic or saprotrophic. several species are sexually transmitted and pathogenic in humans. others are found on cats, dogs, and barnyard fowl. ureaplasma ureaplasma is the second of two genera of bacteria belonging to the family mycoplasmataceae. as the name implies, ureaplasma is urease positive. this genera is distinct from other genera in mollicutes in that it hydrolyses urea for generation of atp. ureaplasma spp. as human pathogens both ureaplasma urealyticum and ureaplasma parvum have been identified as important human pathogens, causing infection in the urogenital tract and, rarely, at distal sites. their role in neonatal disease and adverse pregnancy outcomes has been well established, and semantic classifications are changing to reflect the nature of the detrimental outcomes these infections are associated with. in the 2010s, mycoplasma genitalium has been re-classified as an sti, and it is likely that with more research, ureaplasma spp. will follow this trend. similar to other pathogens such as chlamydia trachomatis, infection with ureaplasma spp. is associated with adverse fertility outcomes in both men and women. both cause non-gonococcal urethritis. ureaplasma spp. were implicated in conditions such as prostatitis and chronic pelvic pain syndrome as early as the 1980s. research in women has lagged several decades behind, but it is now becoming more clear how ureaplasma spp. contribute to etiologies such as interstitial cystitis/painful bladder syndrome. ureaplasma spp. are associated with alterations in host environment that increase susceptibility to other infections such as bacterial vaginosis and vaginal candidiasis. ureaplasma spp. can cause reactive arthritis as well as directly infect the synovium. some case studies have suggested a causative role in complex regional pain syndrome/reflex sympathetic dystrophy syndrome. phylogeny the currently accepted taxonomy is based on the list of prokaryotic names with standing in nomenclature (lpsn) and national center for biotechnology information (ncbi) 16s rrna based ltp_12_2021 gtdb 07-rs207 by genome taxonomy database mollicutes metamycoplasmataceae mycoplasmoidales spiroplasma species-group 3 mycoplasmoidaceae mycoplasmatales spiroplasma spiroplasma species-group 2 "edwardiiplasma" entomoplasmataceae entomoplasma mesoplasma corruscae mesoplasma mycoplasmataceae "tullyiplasma" williamsoniiplasma mycoplasma part mycoplasmatales "ca. spiroplasma holothuricola" mycoplasmoidaceae "ca. hepatoplasma" metamycoplasmataceae vbwq01 spiroplasma species-group 3 mycoplasmataceae spiroplasma spiroplasma species-group 2 "edwardiiplasma" williamsoniiplasma "tullyiplasma" entomoplasma mesoplasma mycoplasma