keratitis–ichthyosis–deafness syndrome keratitis–ichthyosis–deafness syndrome keratitis–ichthyosis–deafness syndrome (kid syndrome), also known as ichthyosiform erythroderma, corneal involvement, and deafness, presents at birth/infancy and is characterized by progressive corneal opacification, either mild generalized hyperkeratosis or discrete erythematous plaques, and neurosensory deafness.: 483, 513 : 565 keratitis-ichthyosis-deafness syndromeother names"erythrokeratodermia progressiva burns", "ichthyosiform erythroderma, corneal involvement, and deafness" it is caused by a mutation in connexin 26.