condoliase condoliase condoliase (hernicore) is a biopharmaceutical for the treatment of lumbar disc herniation. it is an enzyme that degrades glycosaminoglycans. condoliaseclinical datatrade nameshernicoreother nameschondroitinase abc; si-6603identifierscas number9024-13-9drugbank12793unii7si2uzg934echa infocard100.029.785 chemical and physical dataformulac5039h7770n1360o1525s22molar mass112508.90 g·mol−1 condoliase is derived from the enzyme mucopolysaccharidase from the bacteria proteus vulgaris. it was approved for use in japan in 2018.