comparison of psychoactive alcohols in alcoholic drinks comparison of psychoactive alcohols in alcoholic drinks general iupac name common name classification cas ethanol alcohol, drinking alcohol, ethyl alcohol, etoh primary 64-17-5 propan-1-ol 1-propanol, 1-propyl alcohol, proh primary 71-23-8 2-(1h-indol-3-yl)ethanol tryptophol primary 526-55-6 2-methylbutan-1-ol 2-methyl-1-butanol (2m1b) secondary 137-32-6 2-methylpropan-1-ol 2-methyl-1-propanol (2m1p), isobutanol primary 78-83-1 2-methylbutan-2-ol 2-methyl-2-butanol (2m2b), tert-amyl alcohol (taa, tert-amylol) tertiary 75-85-4 2-methylpropan-2-ol 2-methyl-2-propanol (2m2p), tert-butyl alcohol ((tba), tert-butanol), t-buoh tertiary 75-65-0 2-phenylethan-1-ol phenethyl alcohol, 2-phenylethanol primary 60-12-8 3-methylbutan-1-ol 3-methyl-1-butanol (3m1b), isoamyl alcohol, isopentyl alcohol (isopentanol) primary 123-51-3 pharmacology iupac name toxic metabolite(s) alcohol by volume (abv) ld50 in rat, oral ethanol acetaldehyde → acetic acid up to 95.6% in rectified spirit 7060 mg/kg propan-1-ol propionaldehyde → propionic acid 2.8% (mean) in jamaican rum: 2384–3130 mg/100 ml. up to 3500 mg/l (0.35%) in spirits. 1870 mg/kg 2-(1h-indol-3-yl)ethanol ? ? ? 2-methylbutan-1-ol ? 1.2% (mean) in bourbon: 910–1390 mg/100 ml 4170 mg/kg 2-methylpropan-1-ol ? 0.9% (mean) in rye mash cistern room: 534–1197 mg/100 ml 2460 mg/kg 2-methylbutan-2-ol none (tertiary alcohol) 0.07% in beer: 70 mg/100 ml (see tert-pentyl alcohol in ref) found in cassava fermented drinks 1000 mg/kg 2-methylpropan-2-ol none (tertiary alcohol) identified, not quantified, in beer 2743 mg/kg 2-phenylethan-1-ol ? 0.1% in non-yeasted cider (kieser 1964): 100 mg/100 ml 1790 mg/kg 3-methylbutan-1-ol ? 1.5% (mean) in french brandy: 859–2108 mg/100 ml 1300 mg/kg difference to ethanol iupac name % intoxication by alcoholic drink (abv x potency compared to etoh / total abv) therapeutic index (potency compared to etoh/etoh ld50:ld50 ratio) potency compared to etoh etoh ld50:ld50 ratio ethanol - - - - propan-1-ol 21%: 2,8×3÷40 0.8 (mean): 0.5-1.1 3 (mean): 2-4 3.8 2-(1h-indol-3-yl)ethanol ? ? ? ? 2-methylbutan-1-ol ? ? ? 1.7 2-methylpropan-1-ol ? ? ? ? 2-methylbutan-2-ol 28%: 0.07×20÷5 2.8 20 7.1 2-methylpropan-2-ol ? ? ? 2.6 2-phenylethan-1-ol ? ? ? ? 3-methylbutan-1-ol ? ? ? 5.4 characteristic iupac name color/form odor taste ethanol clear, colorless, very mobile liquid mild, rather pleasant; like wine or whiskey. weak, ethereal, vinous odor. burning, slightly sweet propan-1-ol colorless liquid similar to ethanol characteristic ripe, fruity flavor. burning taste 2-(1h-indol-3-yl)ethanol ? ? ? 2-methylbutan-1-ol oily, clear liquid. colorless liquid characteristic, disagreeable odor. pungent, repulsive taste 2-methylpropane-1-ol colorless, oily liquid. clear, colorless, refractive, mobile liquid. suffocating odor of fusel oil. slightly suffocating; nonresidual alcoholic. sweet, musty odor sweet whiskey taste 2-methylbutan-2-ol colorless liquid characteristic odor. camphor odor burning taste 2-methylpropan-2-ol colorless liquid or solid (crystals) (above 78 degrees f) camphor-like odor ? 2-phenylethan-1-ol ? intense odour of roses burning 3-methylbutan-1-ol oily, clear liquid. colorless liquid. characteristic, disagreeable odor. pungent, repulsive taste