xap044 xap044 xap044 is a drug which acts as a potent and selective antagonist of the metabotropic glutamate receptor 7 (mglur7). it inhibits long-term potentiation in the amygdala and inhibits responses associated with stress and anxiety in animal models, as well as being used to study the role of mglur7 in various other processes. xap044identifiers iupac name 7-hydroxy-3-(4-iodophenoxy)-4h-chromen-4-one cas number196928-50-4 ypubchem cid5428913iuphar/bps8545chemspider4558326chemical and physical dataformulac15h9io4molar mass380.137 g·mol−13d model (jsmol)interactive image smiles c1=cc(=cc=c1oc2=coc3=c(c2=o)c=cc(=c3)o)i inchi inchi=1s/c15h9io4/c16-9-1-4-11(5-2-9)20-14-8-19-13-7-10(17)3-6-12(13)15(14)18/h1-8,17hkey:xxzkjjywinsumj-uhfffaoysa-n