molidustat molidustat molidustat is a drug which acts as an hif prolyl-hydroxylase inhibitor and thereby increases endogenous production of erythropoietin, which stimulates production of hemoglobin and red blood cells. it is in phase iii clinical trials for the treatment of anemia caused by chronic kidney disease. due to its potential applications in athletic doping, it has also been incorporated into screens for performance-enhancing drugs. molidustatclinical datatrade namesvarenzin-ca1other namesbay 85-3934routes ofadministrationby mouthatc codenonelegal statuslegal status us: ℞-only identifiers iupac name 2-(6-morpholin-4-ylpyrimidin-4-yl)-4-(triazol-1-yl)-1h-pyrazol-3-one cas number1154028-82-61375799-59-9pubchem cid59603622drugbankdb15642dbsalt002944chemspider3092247632699298unii9jh486cz13ci0ne7c96tkeggd12122chemblchembl3646118pdb liganda1h (pdbe, rcsb pdb)comptox dashboard (epa)dtxsid80151089 echa infocard100.248.923 chemical and physical dataformulac13h14n8o2molar mass314.309 g·mol−13d model (jsmol)interactive image smiles c1coccn1c2=nc=nc(=c2)n3c(=o)c(=cn3)n4c=cn=n4 inchi inchi=1s/c13h14n8o2/c22-13-10(20-2-1-16-18-20)8-17-21(13)12-7-11(14-9-15-12)19-3-5-23-6-4-19/h1-2,7-9,17h,3-6h2key:ijmbokotalxlks-uhfffaoysa-n veterinary use molidustat is indicated for the control of nonregenerative anemia associated with chronic kidney disease in cats. the us food and drug administration (fda) conditionally approved it in may 2023. the reasonable expectation of effectiveness of molidustat was evaluated in a study conducted in two phases. the first phase involved a multi-center, double-masked, randomized, placebo-controlled field effectiveness and safety study. the second phase was an unmasked, optional continuation of the field study. the study enrolled 23 cats from 4 to 17 years of age from various breeds or breed mixes diagnosed with nonregenerative anemia associated with ckd. the fda granted conditional approval of varenzin-ca1 to elanco us inc.