dha-paclitaxel dha-paclitaxel dha-paclitaxel (or taxoprexin) is an investigational drug (from protarga inc) made by linking paclitaxel to docosahexaenoic acid (dha), a fatty acid that is easily taken up by tumor cells; the dha-paclitaxel “appears not to be cytotoxic until the bond with dha is cleaved within the cell.” the advantage of dha-paclitaxel over paclitaxel is dha-paclitaxel's ability to carry much higher concentrations of paclitaxel to the cells, which are maintained for longer periods in the tumor cells, thus increasing their action. with increased activity, dha-paclitaxel, also known as taxoprexin, may have a more successful response in cancer patients than taxol, and it may be able to treat more types of cancer than taxol has been able to treat. dha-paclitaxel names iupac name 1,7β-dihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4α,10β,13α-tetrayl 4,10-diacetate 13-oxy}-3-phenylpropanoate] 2-benzoate systematic iupac name (2ar,4s,4as,6r,9s,11s,12s,12ar,12bs)-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1h-7,11-methanobenzoxetoannulene-6,9,12,12b-tetrayl 6,12b-diacetate 9-oxy}-3-phenylpropanoate] 12-benzoate other names docosahexaenoyl-paclitaxel; taxoprexin identifiers cas number 199796-52-6 y 3d model (jsmol) interactive image chemspider 5293670 n pubchem cid 6918473 unii oje5810c4f y comptox dashboard (epa) dtxsid00873216 inchi inchi=1s/c69h81no15/c1-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-35-42-55(74)83-59(57(49-36-29-26-30-37-49)70-63(76)50-38-31-27-32-39-50)65(78)82-52-44-69(79)62(84-64(77)51-40-33-28-34-41-51)60-67(7,53(73)43-54-68(60,45-80-54)85-48(4)72)61(75)58(81-47(3)71)56(46(52)2)66(69,5)6/h9-10,12-13,15-16,18-19,21-22,24-34,36-41,52-54,57-60,62,73,79h,8,11,14,17,20,23,35,42-45h2,1-7h3,(h,70,76)/b10-9-,13-12-,16-15-,19-18-,22-21-,25-24-/t52-,53-,54+,57-,58+,59+,60-,62-,67+,68-,69+/m0/s1 nkey: lrczqsdqzjbhaf-pubgewhcsa-n ninchi=1/c69h81no15/c1-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-35-42-55(74)83-59(57(49-36-29-26-30-37-49)70-63(76)50-38-31-27-32-39-50)65(78)82-52-44-69(79)62(84-64(77)51-40-33-28-34-41-51)60-67(7,53(73)43-54-68(60,45-80-54)85-48(4)72)61(75)58(81-47(3)71)56(46(52)2)66(69,5)6/h9-10,12-13,15-16,18-19,21-22,24-34,36-41,52-54,57-60,62,73,79h,8,11,14,17,20,23,35,42-45h2,1-7h3,(h,70,76)/b10-9-,13-12-,16-15-,19-18-,22-21-,25-24-/t52-,53-,54+,57-,58+,59+,60-,62-,67+,68-,69+/m0/s1key: lrczqsdqzjbhaf-pubgewhcbo smiles o=c(c1ccccc1)n(c2ccccc2)(oc(=o)cc\c=c/c\c=c/c\c=c/c\c=c/c\c=c/c\c=c/cc)c(=o)o5c(=c4/(oc(=o)c)c(=o)7(((oc(=o)c3ccccc3)(o)(c4(c)c)c5)6(oc(=o)c)(oc6)c7o)c)/c properties chemical formula c69h81no15 molar mass 1164.399 g·mol−1 except where otherwise noted, data are given for materials in their standard state (at 25 °c , 100 kpa). n verify (what is yn ?) infobox references clinical trials in 2007, a phase ii clinical trial reported "modest activity in patients with oesophago-gastric cancer".