dianicline dianicline dianicline (ssr-591,813) is a drug developed by sanofi-aventis which acts as a partial agonist at neural nicotinic acetylcholine receptors. it is subtype-selective, binding primarily to the α4β2 subtype. it is being developed as a medication for the treatment of nicotine dependence to assist in smoking cessation. dianicline is very similar to the already marketed drug varenicline and it is unclear what advantages it will have over the older drug, although it may have an improved side effect profile. it has been through human trials up to phase ii, although results have not yet been reported. drug development has been discontinued after reporting of unfavourable results during phase iii trials. dianiclineclinical dataatc codenoneidentifiers iupac name (5as,8s,10ar)-5a,6,9,10-tetrahydro,7h,11h-8,10a-methanopyridopyranoazepine cas number292634-27-6 ypubchem cid9816447chemspider8352269 nuniiy0snm34c6ochemblchembl187927 nchemical and physical dataformulac13h16n2omolar mass216.278 g·mol−13d model (jsmol)interactive image smiles c1cn2cc3(c2)1oc4=c(c3)n=cc=c4 inchi inchi=1s/c13h16n2o/c1-2-11-10(14-5-1)8-13-4-7-15(9-13)6-3-12(13)16-11/h1-2,5,12h,3-4,6-9h2/t12-,13+/m0/s1 nkey:supruphaexpgpf-qwhcgfszsa-n n ny (what is this?) (verify)