doxycycline. only in combination with artesunate 50 mg. for use only for the treatment of plasmodium vivax infection. for use only in combination with chloroquine. for the treatment of 1st and 2nd stage of human african trypanosomiasis due to trypanosoma brucei gambiense infection. to be used for the treatment of trypanosoma brucei gambiense infection. to be used for the treatment of the initial phase of trypanosoma brucei rhodesiense infection. to be used for the treatment of trypanosoma brucei gambiense infection only to be used in combination with eflornithine, for the treatment of trypanosoma brucei gambiense infection. etanercept and infliximab are alternatives, including quality-assured biosimilars including quality-assured biosimilars including quality-assured biosimilars alternatives limited to prednisone alternatives limited to epoetin alfa, beta and theta, darbepoetin alfa, and their quality-assured biosimilars. alternatives are limited to nadroparin, dalteparin, and their quality-assured biosimilars. alternatives are limited to the oral form of deferasirox. polygeline, injectable solution, 3.5% is considered as equivalent. alternatives limited to 4th level atc chemical subgroup (c09aa ace inhibitors, plain) alternatives limited to 4th level atc chemical subgroup (d01ac imidazole and triazole derivatives) excluding combinations alternatives limited to 4th level atc chemical subgroup (d07ac corticosteroids, potent (group iii)) alternatives limited to calcitriol and tacalcitol alternatives limited to podophyllotoxin alternatives limited to precipitated sulfur topical ointment alternatives limited to atropine and cyclopentolate alternatives limited to propanol alternatives limited to iodine alternatives limited to 4th level atc chemical subgroup (d08ae phenol and derivatives) alternatives limited to chlorothiazide and chlorthalidone alternatives limited to 4th level atc chemical subgroup (a02bc proton pump inhibitors) excluding combinations alternatives limited to 4th level atc chemical subgroup (a02ba h2-receptor antagonists) excluding combinations in acute diarrhoea zinc sulfate should be used as an adjunct to oral rehydration salts alternatives limited to insulin detemir, insulin degludec, and insulin glargine, including quality-assured biosimilars carbimazole is an alternative depending on local availability. for use when alternative first-line treatment is not appropriate or available exact type to be defined locally. recommended for certain regions recommended for some high-risk populations recommended for immunisation programmes with certain characteristics infections due to chlamydia trachomatis or neisseria gonorrhoeae. alternatives limited to amikacin, kanamycin, netilmicin, and tobramycin alternatives limited to 4th level atc chemical subgroup (s01ae fluoroquinolones) alternatives limited to chlortetracycline and oxytetracycline alternatives limited to 4th level atc chemical subgroup (s01ha local anaesthetics) excluding cocaine and combinations alternatives limited to homatropine hydrobromide or cyclopentolate hydrochloride. alternatives limited to indometacin alternatives limited to prostaglandin e2 alternatives limited to beclometasone, ciclesonide, flunisolide, fluticasone, and mometasone alternatives limited to terbutaline ergocalciferol can be used as an alternative. alternatives limited to ofloxacin for use for rheumatic fever, juvenile arthritis, kawasaki disease