basopenia basopenia basopenia (or basocytopenia) is a form of agranulocytosis associated with a deficiency of basophils. it has been proposed as an indicator of ovulation. it is difficult to detect without flow cytometry, because normal levels are so low. it can be defined as less than 0.01 x 109 / l. basopeniaspecialtyhematology associated conditions hereditary absence of basophils (very rare) elevated levels of glucocorticoids hyperthyroidism or treatment with thyroid hormones ovulation hypersensitivity reactions urticaria anaphylaxis drug-induced reactions leukocytosis (in association with diverse disorders)