sb-612,111 sb-612,111 sb-612,111 is an opioid receptor ligand which is a potent and selective antagonist for the nociceptin receptor (orl-1), several times more potent than the older drug j-113,397. it does not have analgesic effects in its own right, but prevents the development of hyperalgesia, and also shows antidepressant effects in animal studies. sb-612,111clinical dataother namessb-612,111identifiers iupac name (5s,7s)-7--1-methyl-6,7,8,9-tetrahydro-5h-benzoannulen-5-ol cas number371980-98-2 npubchem cid10047612iuphar/bps1693chemspider8223175 nchemblchembl559569 ncomptox dashboard (epa)dtxsid40610405 chemical and physical dataformulac24h29cl2nomolar mass418.40 g·mol−13d model (jsmol)interactive imageinteractive image smiles cc1=cc=cc2=c1cc(c2o)cn3ccc(cc3)c4=c(c=cc=c4cl)clcc1=c2cc(c(c2=cc=c1)o)cn3ccc(cc3)c4=c(c=cc=c4cl)cl inchi inchi=1s/c24h29cl2no/c1-16-4-2-5-20-19(16)9-8-17(14-23(20)28)15-27-12-10-18(11-13-27)24-21(25)6-3-7-22(24)26/h2-7,17-18,23,28h,8-15h2,1h3/t17-,23-/m0/s1 nkey:ohrdcqfcawldbp-sburezexsa-n n ny (what is this?) (verify)