pivagabine pivagabine pivagabine (inn; brand name tonerg), also known as n-pivaloyl-γ-aminobutyric acid or n-pivaloyl-gaba, is an antidepressant and anxiolytic drug which was introduced in italy in 1997 for the treatment of depressive and maladaptive syndromes. but it was discontinued in italy (according to martindale). originally believed to function as a prodrug to gaba, pivagabine is now believed to act somehow via modulation of corticotropin-releasing factor (crf). pivagabine names preferred iupac name 4-(2,2-dimethylpropanamido)butanoic acid identifiers cas number 69542-93-4 y 3d model (jsmol) interactive image chemspider 62118 y echa infocard 100.067.287 ec number 274-038-3 kegg d07342 y mesh n-trimethylacetyl-4-aminobutyric+acid pubchem cid 68888 unii c53sv0wo4v y comptox dashboard (epa) dtxsid3046162 inchi inchi=1s/c9h17no3/c1-9(2,3)8(13)10-6-4-5-7(11)12/h4-6h2,1-3h3,(h,10,13)(h,11,12) ykey: srpnqdxrvrctnk-uhfffaoysa-n y smiles cc(c)(c)c(=o)ncccc(o)=o properties chemical formula c9h17no3 molar mass 187.239 g·mol−1 pharmacology atc code n06ax15 (who) routes ofadministration oral pharmacokinetics: biological half-life 6.4 hours legal status in general: ℞ (prescription only) related compounds related alkanoic acids aceglutamiden-acetylglutamic acidcitrulline except where otherwise noted, data are given for materials in their standard state (at 25 °c , 100 kpa). infobox references