altinicline altinicline altinicline (sib-1508y, sib-1765f) is a drug which acts as an agonist at neural nicotinic acetylcholine receptors with high selectivity for the α4β2 subtype. it stimulates release of dopamine and acetylcholine in the brain in both rodent and primate models, and progressed as far as phase ii clinical trials for parkinson's disease, where "no antiparkinsonian or cognitive-enhancing effects were demonstrated", although its current status is unclear. altiniclineclinical dataatc codenoneidentifiers iupac name (2s)-3-ethynyl-5-(1-methylpyrrolidin-2-yl)pyridine cas number179120-92-4 ypubchem cid3036156chemspider2300234 yuniirj9v9v09vmchemblchembl111659 ychemical and physical dataformulac12h14n2molar mass186.252 g·mol−13d model (jsmol)interactive image smiles c2ncc(c#c)cc2c1cccn1c inchi inchi=1s/c12h14n2/c1-3-10-7-11(9-13-8-10)12-5-4-6-14(12)2/h1,7-9,12h,4-6h2,2h3/t12-/m0/s1 ykey:nupudykeejnzrg-lbprgkrzsa-n y (verify)