gr-89696 gr-89696 gr-89696 is a drug which acts as a highly selective κ-opioid agonist. it shows selective effects in different animal models and it is thought it may be a subtype-selective agonist for the κ2 subtype. recent studies have suggested that gr-89696 and related κ2-selective agonists may be useful for preventing the itching which is a common side effect of conventional opioid analgesic drugs, without the additional side effects of non-selective kappa agonists. gr-89696identifiers iupac name methyl 4--3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate cas number126766-32-3 ypubchem cid3505iuphar/bps1649chemspider3385uniiydf52k5sdrchemblchembl277863 ncomptox dashboard (epa)dtxsid50875164 chemical and physical dataformulac19h25cl2n3o3molar mass414.33 g·mol−13d model (jsmol)interactive image smiles clc1ccc(cc1cl)cc(=o)n2ccn(c(=o)oc)cc2cn3cccc3 inchi inchi=1s/c19h25cl2n3o3/c1-27-19(26)23-8-9-24(15(13-23)12-22-6-2-3-7-22)18(25)11-14-4-5-16(20)17(21)10-14/h4-5,10,15h,2-3,6-9,11-13h2,1h3key:hjuakzykcanooz-uhfffaoysa-n ny (what is this?) (verify)