7α-methylestradiol 7α-methylestradiol 7α-methylestradiol (7α-me-e2), also known as 7α-methylestra-1,3,5(10)-triene-3,17β-diol, is a synthetic estrogen and an active metabolite of the androgen/anabolic steroid trestolone. it is considered to be responsible for the estrogenic activity of trestolone. the compound shows about the same affinity for the estrogen receptor as estradiol. relative affinities (%) of 7α-methylestradiol and related steroids compoundprarergrmrshbgcbg estradiol2.67.91000.60.138.7<0.1 7α-methylestradiol1–315–25101<1<1 ? ? trestolone50–75100–125 ?<1 ? ? ? values are percentages (%). reference ligands (100%) were progesterone for the pr, testosterone for the ar, e2 for the er, dexa for the gr, aldosterone for the mr, dht for shbg, and cortisol for cbg. not to be confused with methylestradiol. 7α-methylestradiolclinical dataother names7α-methyl-e2; 7α-me-e2; 7α-methylestra-1,3,5(10)-triene-3,17β-dioldrug classestrogenidentifiers iupac name (7r,8r,9s,13s,14s,17s)-7,13-dimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopentaphenanthrene-3,17-diol cas number10448-97-2 ypubchem cid10424124uniivd3ug279pschemical and physical dataformulac19h26o2molar mass286.415 g·mol−13d model (jsmol)interactive image smiles 12cc(o)1(c)cc1()c3=cc=c(o)c=c3c(c)21 inchi inchi=1/c19h26o2/c1-11-9-12-10-13(20)3-4-14(12)15-7-8-19(2)16(18(11)15)5-6-17(19)21/h3-4,10-11,15-18,20-21h,5-9h2,1-2h3/t11-,15-,16+,17+,18-,19+/s2key:dxwwyjwufulmap-bqxdhoisna-n