pigmented spindle cell nevus pigmented spindle cell nevus a pigmented spindle cell nevus is a skin condition characterized by a dark brown to black macule or papule, usually less than 6 mm. pigmented spindle cell nevusother namespigmented spindle cell tumor of reed, pigmented variant of spitz nevusmicrograph of a pigmented spindle cell nevus (top of image). h&e stain.specialtydermatology it was characterized in 1975.