latin, german, and spanish are flutamidum, flutamid, and flutamida, respectively. the medication has also been referred to by the name niftolide. brand names brand names of flutamide include or have included cebatrol, cytomid, drogenil, etaconil, eulexin, flucinom, flumid, flutacan, flutamid, flutamida, flutamin, flutan, flutaplex, flutasin, fugerel, profamid, and sebatrol, among others. availability flutamide is marketed widely throughout the world, including in the united states, canada, europe, australia, new zealand, south africa, central and south america, east and southeast asia, india, and the middle east. research prostate cancer the combination of an estrogen and flutamide as a form of combined androgen blockade for the treatment of prostate cancer has been researched. enlarged prostate flutamide has been studied in the treatment of benign prostatic hyperplasia (bph; enlarged prostate) in men in several clinical studies. it has been found to reduce prostate volume by about 25%, which is comparable to the reduction achieved with the 5α-reductase inhibitor finasteride. unfortunately, it has been associated with side effects in these studies including gynecomastia and breast tenderness (in about 50% of patients), gastrointestinal disturbances such as nausea, diarrhea, and flatulence, and hepatotoxicity, although sexual function including libido and erectile potency were maintained. breast cancer flutamide was studied for the treatment of advanced breast cancer in two phase ii clinical trials but was found to be ineffective. out of a total of 47 patients, only three short-term responses occurred. however, the patients in the studies were selected irrespective of ar, er, pr, or her2 status, which were all unknown. psychiatric disorders flutamide has been studied in the treatment of bulimia nervosa in women. flutamide was found to be effective in the treatment of obsessive–compulsive disorder (ocd) in men with comorbid tourette's syndrome in one small randomized controlled trial. conversely, it was ineffective in patients with ocd in another study. more research is necessary to determine whether flutamide is effective in the treatment of ocd.