difludiazepam difludiazepam difludiazepam (ro07-4065) is a benzodiazepine derivative which is the 2',6'-difluoro derivative of fludiazepam. it was invented in the 1970s but was never marketed, and has been used as a research tool to help determine the shape and function of the gabaa receptors, at which it has an ic50 of 4.1nm. difludiazepam has subsequently been sold as a designer drug, and was first notified to the emcdda by swedish authorities in 2017. difludiazepamlegal statuslegal status ca: schedule iv de: npsg (industrial and scientific use only) uk: under psychoactive substances act identifiers iupac name 7-chloro-5-(2,6-difluorophenyl)-1-methyl-1h-benzo diazepin-2(3h)-one cas number39080-67-6 ypubchem cid44366236chemspider23222150unii7n3b9xec7bchemblchembl346673chemical and physical dataformulac16h11clf2n2omolar mass320.72 g·mol−13d model (jsmol)interactive image smiles fc3cccc(f)c3c2=ncc(=o)n(c)c1ccc(cl)cc12 inchi inchi=1s/c16h11clf2n2o/c1-21-13-6-5-9(17)7-10(13)16(20-8-14(21)22)15-11(18)3-2-4-12(15)19/h2-7h,8h2,1h3key:dunfpasorltegn-uhfffaoysa-n