4-ho-dipt 4-ho-dipt 4-hydroxy-n,n-diisopropyltryptamine (4-ho-dipt or iprocin) is a synthetic psychedelic drug. it is a higher homologue of psilocin, 4-ho-det, and is a positional isomer of 4-ho-dpt and has a tryptamine molecular sub-structure. 4-ho-diptclinical dataroutes ofadministrationorallegal statuslegal status de: npsg (industrial and scientific use only) uk: class a us: unscheduled pharmacokinetic dataelimination half-life1-2 hrsidentifiers iupac name 3--1h-indol-4-ol cas number132328-45-1 yhcl: 63065-90-7 ychemspider10579819 yuniiyg9ous518bhcl: ke76pmq2p3 ycomptox dashboard (epa)dtxsid50618836 echa infocard100.214.853 chemical and physical dataformulac16h24n2omolar mass260.381 g·mol−13d model (jsmol)interactive image smiles cc(c)n(ccc1cc2cccc(o)c12)c(c)c inchi inchi=1s/c16h24n2o/c1-11(2)18(12(3)4)9-8-13-10-17-14-6-5-7-15(19)16(13)14/h5-7,10-12,17,19h,8-9h2,1-4h3 ykey:kbrykxcbgisxqv-uhfffaoysa-n y ny (what is this?) (verify) 4-ho-dipt powder dosage 4-ho-dipt is orally active at around 3 mg and above, and its effects last for 2–3 hours. higher doses such as those above 30 mgs can increase the duration of the effects significantly. effects the effects of 4-ho-dipt are broadly comparable to those of other serotonergic psychedelics such as lsd and psilocin, but they are distinguished by their relative brevity. shulgin "doubt that there is another psychedelic drug, anywhere, that can match this one for speed, for intensity, for brevity, and sensitivity to dose, at least one that is active orally." an idiosyncratic effect of the drug, also noted by shulgin, is its tendency to induce tremors. some users have reported a minor audio distortion with lower dosages. higher dosages increase the polarity of the distortion. it is defined as being slightly lower in pitch and creating several different effects, such as pitch bend, volume distortion, and rate distortion. as with most dipt psychedelics, music can become more dissonant and less harmonious. users have also reported a visual distortion widely comparable to the hallucinogen lsd. pharmacology pharmacokinetics binding sites binding affinity ki (μm) action 5-ht1a 5.7 ??? 5-ht2a 0.728 partial agonist 5-ht2c 2.8 ??? d1 >25 ??? d2 >25 ??? d3 >25 ??? α1a >12 ??? α2a 15 ??? taar1 >15 ??? h1 9.8 ??? sert 1.8 inhibitor dat >26 ??? net 11 inhibitor clinical trials ft-104, a prodrug to 4-ho-dipt, has entered double blind, randomized, placebo controlled, phase 1 clinical trials in healthy volunteers at the royal adelaide hospital in australia for the treatment of postpartum depression and treatment-resistant depression. it is propably a less neurotoxic alternative to alpha-methyltryptamine (αmt, amt, indopan) and alpha-ethyltryptamine (αet, aet, monase). ft-104 legal status finland scheduled in government decree on psychoactive substances banned from the consumer market. germany scheduled in new psychoactive substances act (npsg). use of covered substances is permitted only for industrial and scientific purposes. sweden sveriges riksdags health ministry statens folkhälsoinstitut classified 4-ho-dipt as "health hazard" under the act lagen om förbud mot vissa hälsofarliga varor (translated act on the prohibition of certain goods dangerous to health) as of mar 1, 2005, in their regulation sfs 2005:26 listed as 4-hydroxi-n,n-diisopropyltryptamin (4-ho-dipt), making it illegal to sell or possess. united states 4-ho-dipt is not scheduled at the federal level in the united states, but it is possible that it could be considered an analog of 5-meo-dipt, in which case purchase, sale, or possession could be prosecuted under the federal analog act. florida "4-hydroxy-n,n-diisopropyltryptamine" is a schedule i controlled substance in the state of florida making it illegal to buy, sell, or possess in florida.