propacetamol propacetamol propacetamol is a prodrug form of paracetamol which is formed from esterification of paracetamol, and the carboxylic acid diethylglycine. this has the advantage of making it more water-soluble. it is used in post-operative care and is delivered by i.v. it is given if the patient is unable to take oral or rectally delivered paracetamol and nonsteroidal anti-inflammatory drugs (nsaids) are contraindicated. the onset of analgesia from propacetamol is more rapid than paracetamol given orally. 2 grams of propacetamol are equivalent to 1g of paracetamol. propacetamolclinical dataahfs/drugs.cominternational drug namesroutes ofadministrationivatc coden02be05 (who) pharmacokinetic dataelimination half-life2.4 hours excretionrenalidentifiers iupac name 4-(acetamido)phenyl n,n-diethylglycinate cas number66532-85-2pubchem cid68865chemspider62097unii5chw4jmr82comptox dashboard (epa)dtxsid3057800 echa infocard100.060.336 chemical and physical dataformulac14h20n2o3molar mass264.325 g·mol−13d model (jsmol)interactive image smiles ccn(cc)cc(=o)oc1=cc=c(c=c1)nc(=o)c inchi inchi=1s/c14h20n2o3/c1-4-16(5-2)10-14(18)19-13-8-6-12(7-9-13)15-11(3)17/h6-9h,4-5,10h2,1-3h3,(h,15,17)key:qtgajcqtlircfl-uhfffaoysa-n (verify)