nosh-aspirin nosh-aspirin nosh-aspirin is a category of new hybrids of aspirin, bearing both nitric oxide (no)- and hydrogen sulfide (h2s)- releasing areas. preliminary studies have found that four nosh variants, evaluated in eleven different human cancer cell lines, were effective in inhibiting the growth of these cell lines. nosh-1 was also devoid of any cellular toxicity, and was comparable to aspirin in its anti-inflammatory properties. chemical structure of nosh-aspirin, with highlighted aspirin (green), sulfide-releasing (yellow), and nitric oxide-releasing (blue) groups.