rostafuroxin rostafuroxin rostafuroxin is a digitoxigenin analog that has been shown to lower blood pressure in an animal model of hypertension. it modulates the effects of the enzyme na+/k+-atpase, which maintains sodium and potassium ion gradients across plasma membranes. rostafuroxin is being studied in clinical trials for the treatment of essential hypertension. rostafuroxin names iupac name 21,23-epoxy-24-nor-5β-chola-20,22-diene-3β,14β,17-triol systematic iupac name (1s,3as,3br,5ar,7s,9as,9bs,11as)-1-(furan-3-yl)-9a,11a-dimethylhexadecahydro-3ah-cyclopentaphenanthrene-1,3a,7-triol identifiers cas number 156722-18-8 3d model (jsmol) interactive image pubchem cid 153976 unii p848lcx62b smiles c12cc(c1cc32cc4(3(cc4(c5=coc=c5)o)o)c)o properties chemical formula c23h34o4 molar mass 374.521 g·mol−1 except where otherwise noted, data are given for materials in their standard state (at 25 °c , 100 kpa). infobox references