rna therapeutics rna therapeutics rna therapeutics are a new class of medications based on ribonucleic acid (rna). research has been working on clinical use since the 1990s, with significant success in cancer therapy in the early 2010s. in 2020 and 2021, mrna vaccines have been developed globally for use in combating the coronavirus disease (covid-19 pandemic). the pfizer–biontech covid-19 vaccine was the first mrna vaccine approved by a medicines regulator, followed by the moderna covid-19 vaccine, and others.