picornain 2a picornain 2a picornain 2a (ec 3.4.22.29, picornavirus endopeptidase 2a, poliovirus protease 2a, rhinovirus protease 2a, 2a protease, 2a proteinase, protease 2a, proteinase 2apro, picornaviral 2a proteinase, y-g proteinase 2a, poliovirus proteinase 2a, poliovirus protease 2apro) is a protease enzyme. this enzyme catalyses the following chemical reaction: selective cleavage of tyr-gly bond in picornavirus polyprotein picornain 2aidentifiersec no.3.4.22.29cas no.103406-62-8 databasesintenzintenz viewbrendabrenda entryexpasynicezyme viewkeggkegg entrymetacycmetabolic pathwaypriamprofilepdb structuresrcsb pdb pdbe pdbsumsearchpmcarticlespubmedarticlesncbiproteins this enzyme is coded by entero-, rhino-, aphto- and cardioviruses.