norbinaltorphimine norbinaltorphimine norbinaltorphimine (nor-bni or nbni) is an opioid antagonist used in scientific research. it is one of the few opioid antagonists available that is highly selective for the κ-opioid receptor, and blocks this receptor without affecting the μ- or δ-opioid receptors, although it has less selectivity in vivo than when used in isolated tissues. nor-bni blocks the effects of κ-opioid agonists in animal models, and produces antidepressant and antipanic-like effects. norbinaltorphimineclinical dataatc codenoneidentifiers iupac name 17,17'-(dicyclopropylmethyl)-6,6',7,7'-6,6'-imino- 7,7'-bimorphinan-3,4',14,14'-tetrol cas number105618-26-6 ypubchem cid3034416iuphar/bps1642chemspider21248347 nunii36ooq86qm1comptox dashboard (epa)dtxsid90897163 chemical and physical dataformulac40h43n3o6molar mass661.799 g·mol−13d model (jsmol)interactive image smiles c1cc1cn2cc345c6=c(c3(2cc7=c4c(=c(c=c7)o)o5)o)c8=c(n6)912ccn((1(c8)o)cc1=c2c(=c(c=c1)o)o9)cc1cc1 inchi inchi=1s/c40h43n3o6/c44-25-7-5-21-13-27-39(46)15-23-24-16-40(47)28-14-22-6-8-26(45)34-30(22)38(40,10-12-43(28)18-20-3-4-20)36(49-34)32(24)41-31(23)35-37(39,29(21)33(25)48-35)9-11-42(27)17-19-1-2-19/h5-8,19-20,27-28,35-36,41,44-47h,1-4,9-18h2/t27-,28-,35+,36+,37+,38+,39-,40-/m1/s1 nkey:apsuxpsybjvpps-yaukwvcosa-n n ny (what is this?) (verify)