org-21465 org-21465 org-21465 is a synthetic neuroactive steroid, with sedative effects resulting from its action as a gabaa receptor positive allosteric modulator. it is similar to related drugs such as org-20599, and was similarly developed as an improved alternative to other sedative steroids such as althesin and allopregnanolone, which despite its superior properties in some respects has not proved to offer enough advantages to be accepted into clinical use. org-21465clinical dataother names2β-(2,2-dimethyl-4-morpholinyl)-3α-hydroxy-11,20-dioxo-5α-pregnan-21-yl methanesulfonateidentifiers iupac name phenanthren-17-yl]-2-oxoethyl]methanesulfonate pubchem cid10697702chemspider8873045chemical and physical dataformulac27h43no7smolar mass525.70 g·mol−13d model (jsmol)interactive image smiles o=s(=o)(occ(=o)5cc15(c)cc(=o)31cc4c(o)(n2cc(occ2)(c)c)c34c)c inchi inchi=1s/c28h45no7s/c1-26(2)16-29(10-11-35-26)21-13-27(3)17(12-22(21)30)6-7-18-19-8-9-20(24(32)15-36-37(5,33)34)28(19,4)14-23(31)25(18)27/h17-22,25,30h,6-16h2,1-5h3/t17-,18-,19-,20+,21-,22-,25+,27-,28-/m0/s1key:sucbeqdwliemeh-jdoqemnxsa-n (verify) chemistry