a deviate bite. the development of dental caries due to the abnormal morphology of the overgrown tooth can be more of a short-term impact that can result in long lasting effects of overall tooth health. this is because unless the patient gets treated, these caries will continue to develop and eventually result in continued degradation of the tooth and cause infections to surrounding teeth and gums. epidemiology macrodontia is a very uncommon dental abnormality which has been reported alongside other dental anomalies. it is reported that macrodontia affects 0.03% of the population. males seem to have a higher predisposition to the disease, with a prevalence of 1.2%. on the other hand, females have a prevalence of around 0.9%. disruptions of regular growth of the teeth and enlargement usually become evident before or between the ages of 11 and 12, when the eruption of the mandibular second premolars usually occur. research direction while there is research regarding the symptoms and effects of macrodontia on patients, there is still a fundamental misunderstanding regarding the specific pathophysiological mechanisms that are exhibited which result in this abnormality. current research has been able to clearly identify methods of observing and diagnosing a patient by using various imaging techniques. there is also an abundance of information regarding treatment options that are mostly concentrated within the cosmetic branch of dentistry to fix the appearance of the teeth as well as simply removing it to halt continuous pain. there is a number of genetic mutations that have been correlated with the prevalence of macrodontia in patients exhibiting this syndrome, such as kbg syndrome or those who overexpress gh, but how this relates to the hard tissue of the teeth and the mechanism by which it affects the enamel and other related factors have yet to be considered. there is no current clinical trials for treatment of this disease as there are a number of procedures which already exist to make the affected teeth smaller; and if all else fails, dentists can simply remove the tooth and replace it with a veneer or bridge in its place.