apica (drug) apica (drug) 1-amino-5-phosphonoindan-1-carboxylic acid (apica) is a drug that is used in neuroscience research. it is a selective antagonist for the group ii metabotropic glutamate receptors (mglur2/3), and has been useful in the study of this receptor subfamily. this article is about the metabotropic glutamate receptor antagonist. for the cannabinoid drug, see apica (synthetic cannabinoid drug). apicaclinical dataatc codenoneidentifiers iupac name 1-amino-5-phosphonoindan-1-carboxylic acid chemspider3881975 ychemblchembl277961 ychemical and physical dataformulac10h12no5pmolar mass257.182 g·mol−13d model (jsmol)interactive image smiles o=p(o)(o)c(c2)ccc1c2ccc1(n)c(o)=o inchi inchi=1s/c10h12no5p/c11-10(9(12)13)4-3-6-5-7(17(14,15)16)1-2-8(6)10/h1-2,5h,3-4,11h2,(h,12,13)(h2,14,15,16) ykey:znqzxihsjudikl-uhfffaoysa-n y (verify)