stigmine stigmine stigmine refers to a class of acetylcholinesterase inhibitors. pyridostigmine, a stigmine derivative. examples include: distigmine neostigmine physostigmine pyridostigmine rivastigmine psychoanaleptics: anti-dementia agents (atc code n06d and others)ache inhibitor medications donepezil galantamine ipidacrine rivastigmine tacrine other medications bifemelane ginkgo folium meclofenoxate (centrophenoxine) memantine nicergoline experimental bace inhibitors lanabecestat verubecestat drugs used for glaucoma preparations and miosis (s01e)sympathomimetics apraclonidine brimonidine (+timolol) clonidine dipivefrine epinephrine parasympathomimeticsmuscarinic aceclidine pilocarpine muscarinic/nicotinic acetylcholine carbachol acetylcholinesterase inhibitors demecarium ecothiopate stigmine (fluostigmine neostigmine physostigmine) paraoxon carbonic anhydrase inhibitors/(sulfonamides) acetazolamide brinzolamide (+timolol, +brimonidine) diclofenamide dorzolamide (+timolol) methazolamide beta blocking agents befunolol betaxolol carteolol levobunolol metipranolol timolol mepindolol prostaglandin analogues (f2α) bimatoprost (+timolol) latanoprost (+netarsudil, +timolol) latanoprostene bunod tafluprost travoprost (+timolol) unoprostone other agents dapiprazole guanethidine netarsudil (+latanoprost) omidenepag ripasudil acetylcholine metabolism and transport modulatorsenzyme(modulators)chat inhibitors: 1-(-benzoylethyl)pyridinium 2-(α-naphthoyl)ethyltrimethylammonium 3-chloro-4-stillbazole 4-(1-naphthylvinyl)pyridine acetylseco hemicholinium-3 acryloylcholine af64a b115 beta cm-54,903 n,n-dimethylaminoethylacrylate n,n-dimethylaminoethylchloroacetate ache inhibitors: reversible: carbamates: aldicarb aminocarb bendiocarb bufencarb carbaryl carbendazim carbetamide carbofuran carbosulfan chlorbufam chloropropham dimetilan ethienocarb ethiofencarb fenobucarb formetanate formparanate methiocarb methomyl metolcarb miotine oxamyl phenmedipham pinmicarb pirimicarb promecarb propamocarb propham propoxur thiodicarb thiofanox; stigmines: distigmine eptastigmine ganstigmine neostigmine +glycopyrronium bromide phenserine physostigmine pyridostigmine quilostigmine rivastigmine terestigmine; others: acotiamide ambenonium caffeine donepezil ea-3990 ea-4056 edrophonium galantamine huperzine a huprine w huprine x huprine y ipidacrine itopride ladostigil minaprine octamethylene-bis(5-dimethylcarbamoxyisoquinolinium bromide) t-1123 t-1152 t-1194 tl-599 tl-1238 tacrine zanapezil irreversible: organophosphates: 2-ethoxycarbonyl-1-methylvinyl cyclohexyl methylphosphonate acephate armine azinphos-ethyl azinphos-methyl bay-29952 bensulide cadusafos carbophenothion chlorethoxyfos chlorfenvinphos chlorpyrifos chlorpyrifos-methyl coumaphos crotylsarin cyanophos cyclosarin (gf) demephion demeton demeton-s-methyl dialifor diazinon dichlorvos dicrotophos dicyclohexyl phosphorofluoridate diisopropylphosphate diisopropyl fluorophosphate dimefox dimethoate dimethyl 4-(methylthio)phenyl phosphate dioxathion disulfoton ea-2012 ea-2054 ea-2098 ea-2192 ea-2613 ea-3148 ea-4352 echothiophate ethylsarin (ge) endothion epn ethion ethoprop fenamiphos fenitrothion fenthion fluorotabun fonofos formothion fosthiazate gd-42 gh gt-45 gv guanitoxin hexaethyl tetraphosphate (hetp) isofluorophate isoxathion leptophos malaoxon malathion mazidox methamidophos methidathion methyl phenkapton methylfluorophosphonylcholine (mfpch) metrifonate mevinphos mipafox monocrotophos mspi naled novichok agent omethoate oxydemeton-methyl paraoxon parathion parathion-methyl phorate phosalone phosfolan phosmet phosphamidon phoxim pirimiphos-methyl profenofos prothoate r-16661 ro 3-0340 ro 3-0346 ro 3-0347 ro 3-0351 ro 3-0352 ro 3-0397 ro 3-0411 ro 3-0412 ro 3-0417 ro 3-0419 ro 3-0422 ro 3-0433 ronnel sarin (gb) schradan soman (gd) sulfotep (tedp) tabun (ga) tebupirimfos temefos terbufos tetrachlorvinphos tetraethyl pyrophosphate (tepp) triazofos tribufos trichlorfon trichloronate tricresyl phosphate ve vg vm vp vs vr vx; others: demecarium fasciculins (green mamba toxins) (1, 2, 3, 4) onchidal (onchidella binneyi) methanesulfonyl fluoride unsorted: α-pinene α-viniferin affinine affinisine arisugacin a bulbocapnine conodurine coronaridine corydaline corynoline crimidine cyclanoline cymserine harmaline kobophenol a lactucopicrin lycorine phosacetim rosmarinic acid stercuronium iodide taspine tetrahydrocannabinol ungeremine ungiminorine dimethylcarbamoyl fluoride bw284c51 tmtfa 3152 ct reactivators: asoxime chloride methoxime obidoxime pralidoxime trimedoxime bromide bche inhibitors: affinine affinisine conodurine cymserine ladostigil profenamine (ethopropazine) rivastigmine tacrine zinc-12613047 many of the other ache inhibitors listed above transporter(modulators)cht inhibitors: hemicholinium-3 (hemicholine) triethylcholine enhancers: coluracetam vacht inhibitors: vesamicol release(modulators)inhibitors snap-25 inactivators: botulinum toxin (a, c, e) vamp inactivators: botulinum toxin (b, d, f, g) others: bungarotoxins (β-bungarotoxin, γ-bungarotoxin) enhancers lphn agonists: α-latrotoxin others: atracotoxins (e.g., robustoxin, versutoxin) crotoxin