ant venom ant venom ant venom is any of, or a mixture of, irritants and toxins inflicted by ants. most ants spray or inject a venom, the main constituent of which is formic acid only in the case of subfamily formicinae. ant venomsterile pustules 3 days after fire ant stings.specialtyemergency medicine ant stings of all extant ant species, about 71% are considered to be stinging species, as some subfamilies have evolutionarily lost the ability to sting. notable examples include a few species of medical importance, such as solenopsis (fire ants), pachycondyla, myrmecia (bulldog ants), and paraponera (bullet ants). in the case of fire ants, the venom consists mainly of alkaloid (>95%) and protein (<1%) components. stinging ants cause a cutaneous condition that is different from that caused by biting venomous ants. particularly painful are stings from fire ants, although the bullet ant's sting is considered by some to be the most painful insect sting.: 450 first aid for fire ant bites includes external treatments and oral medicines. external treatments: a topical steroid cream (hydrocortisone), or one containing aloe vera oral medicines: antihistamines applying zinc oxide or calamine lotion. severe allergic reactions can be caused by ant stings in particular and venomous stings in general, including severe chest pain, nausea, severe sweating, loss of breath, serious swelling, fever, dizziness, and slurred speech; they can be fatal if not treated.