clofedanol clofedanol clofedanol (inn) or chlophedianol (ban), sold under the brand name ninjacof among others, is a centrally acting cough suppressant used in the treatment of dry cough. clofedanol has local anesthetic, antispasmodic, and antihistamine properties, and may have anticholinergic effects at high doses. clofedanolclinical datatrade namescoldrin, gentos, pectolitan, ulo, uloneahfs/drugs.commicromedex detailed consumer informationroutes ofadministrationoralatc coder05db10 (who) identifiers iupac name 1-(2-chlorophenyl)-3-dimethylamino-1-phenyl-propan-1-ol cas number791-35-5 ypubchem cid2795iuphar/bps7324drugbankdb04837 ychemspider2693 yunii42c50p12apkeggd07721 ychemblchembl1201313 ncomptox dashboard (epa)dtxsid4022789 echa infocard100.011.219 chemical and physical dataformulac17h20clnomolar mass289.80 g·mol−13d model (jsmol)interactive image smiles clc1ccccc1c(o)(c2ccccc2)ccn(c)c inchi inchi=1s/c17h20clno/c1-19(2)13-12-17(20,14-8-4-3-5-9-14)15-10-6-7-11-16(15)18/h3-11,20h,12-13h2,1-2h3 ykey:wrchfmbcvffyeq-uhfffaoysa-n y ny (what is this?) (verify) side effects adverse effects may include irritability, drowsiness, nightmares, vertigo, nausea or vomiting, visual disturbances or hallucinations, and urticaria. there are potential interactions with other anticholinergics, cns depressants, and alcohol. pharmacology unlike many other antitussive drugs such as dextromethorphan, it binds poorly to the sigma-1 receptor. society and culture chlophedianol was approved for otc status in 1987 by the fda otc monograph process and its safety and efficacy data are limited. it was formerly sold over-the-counter in the united states under the trade name ulo, as a syrup with a dosage of 25 mg/5 ml; however, it has been withdrawn from the market. it is marketed in canada under the trade name ulone. gm pharmaceuticals owns the patents to 113 combinations with chlophedianol and was the first company to launch the cough suppressant in the united states. it is sold in japan as an over-the-counter drug under the name coldrin. it has been marketed in germany as pectolitan and in spain as gentos.