diiodohydroxyquinoline diiodohydroxyquinoline the quinoline derivative diiodohydroxyquinoline (inn), or iodoquinol (usan), can be used in the treatment of amoebiasis. diiodohydroxyquinoline names preferred iupac name 5,7-diiodoquinolin-8-ol other names diquinol, iodoxin, diiodoquin, amebaquin identifiers cas number 83-73-8 y 3d model (jsmol) interactive image chebi chebi:5950 chembl chembl86754 n chemspider 3597 n echa infocard 100.001.362 kegg d00581 y mesh iodoquinol pubchem cid 3728 unii 63w7ie88k8 y comptox dashboard (epa) dtxsid6023155 inchi inchi=1s/c9h5i2no/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13h nkey: uxzfqzandvdgmm-uhfffaoysa-n ninchi=1/c9h5i2no/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13hkey: uxzfqzandvdgmm-uhfffaoyaf smiles c1=cc2=c(c(=c(c=c2i)i)o)n=c1 properties chemical formula c9h5i2no molar mass 396.951 pharmacology atc code g01ac01 (who) except where otherwise noted, data are given for materials in their standard state (at 25 °c , 100 kpa). n verify (what is yn ?) infobox references it is poorly absorbed from the gastrointestinal tract and is used as a luminal amebicide. it acts by chelation of ferrous ions essential for metabolism. it was discovered by adco co. and introduced as diiodohydroxyquinoline. susceptibility of dientamoeba fragilis has been measured. iodoquinol is an amebicide used against entamoeba histolytica, and it is active against both cyst and trophozoites that are localized in the lumen of the intestine. it is considered the drug of choice for treating asymptomatic or moderate forms of amebiasis. the full mechanism of action is unknown. iodoquinol is used for diseases caused by moderate intestinal amebiasis. diodoquin enhances zinc absorption in the zinc deficiency disorder acrodermatitis enteropathica, probably because diodoquin act as a zinc ionophore.