tmc-647055 tmc-647055 tmc-647055 is an experimental antiviral drug which was developed as a treatment for hepatitis c, and is in clinical trials as a combination treatment with ribavirin and simeprevir. it acts as a ns5b polymerase inhibitor. tmc-647055legal statuslegal status us: investigational drug identifiers iupac name 28-cyclohexyl-22-methoxy-10,16-dimethyl-9,9-dioxo-13-oxa-9λ6-thia-1,8,10,16-tetrazapentacyclononacosa-2,4,6(29),18,20(25),21,23,26(28)-octaene-7,17-dione cas number1204416-97-6pubchem cid44556044drugbankdb11822chemspider28522119unii11bd024g7jchemblchembl2043025comptox dashboard (epa)dtxsid90152860 chemical and physical dataformulac32h38n4o6smolar mass606.7 g·mol−13d model (jsmol)interactive image smiles cn1ccoccn(s(=o)(=o)nc(=o)c2=cc3=c(c=c2)c(=c4n3cc(=cc5=c4c=cc(=c5)oc)c1=o)c6ccccc6)c inchi inchi=1s/c32h38n4o6s/c1-34-13-15-42-16-14-35(2)43(39,40)33-31(37)22-9-11-27-28(19-22)36-20-24(32(34)38)17-23-18-25(41-3)10-12-26(23)30(36)29(27)21-7-5-4-6-8-21/h9-12,17-19,21h,4-8,13-16,20h2,1-3h3,(h,33,37)key:uobyjvfbfslctq-uhfffaoysa-n