gemazocine gemazocine gemazocine (r-15,497), also known as cyclogemine, is a non-selective opioid antagonist of the benzomorphan class. it may have partial agonist properties at some of the opioid receptors, such as at the kappa receptor (as it induces dysphoric effects in humans), but seems to be generally antagonistic in its actions. gemazocineclinical dataatc codenoneidentifiers iupac name 10-(cyclopropylmethyl)-1-ethyl-13,13-dimethyl-10-azatricyclotrideca-2,4,6-trien-4-ol cas number54063-47-7pubchem cid219096chemspider189916uniiv1a2s0lb62chemblchembl2105066chemical and physical dataformulac20h29nomolar mass299.458 g·mol−13d model (jsmol)interactive image smiles oc1ccc4c(c1)c2(c(c(n(cc2)cc3cc3)c4)(c)c)cc inchi inchi=1s/c20h29no/c1-4-20-9-10-21(13-14-5-6-14)18(19(20,2)3)11-15-7-8-16(22)12-17(15)20/h7-8,12,14,18,22h,4-6,9-11,13h2,1-3h3key:afzocgntfcgoee-uhfffaoysa-n