schiller–duval body schiller–duval body schiller–duval body is a cellular structure seen by microscope in endodermal sinus tumors (yolk sac tumors) which are the most common testicular cancer in children. schiller-duval bodies are present in approximately 50% of these tumors, and if found are pathognomonic. they are named for mathias-marie duval and walter schiller who described them in the late nineteenth century. biopsy specimen of yolk sac tumor with schiller-duval body, h&e stain schiller–duval bodies are said to resemble a glomerulus. they have a mesodermal core with a central capillary, all lined by flattened layers of both visceral and parietal cells. immunofluorescent stain may show eosinophilic hyalin-like globules both inside and outside the cytoplasm that contain afp and alpha 1-antitrypsin.