estradiol anthranilate estradiol anthranilate estradiol anthranilate, or estradiol 3-anthranilate, is a synthetic estrogen and estrogen ester – specifically, the c3 anthranilic acid ester of estradiol – which was described in the late 1980s and was never marketed. in dogs, the oral bioavailability of estradiol anthranilate was found to be 5-fold higher than that of unmodified estradiol. however, a subsequent study found that the oral bioavailability of estradiol and estradiol anthranilate did not differ considerably in rats (4.3% and 3.2%, respectively), suggestive of a major species difference. estradiol anthranilateclinical dataother namesestradiol 3-anthranilateroutes ofadministrationby mouthdrug classestrogen; estrogen esteridentifiers iupac name phenanthren-3-yl] 2-aminobenzoate cas number111111-97-8 ypubchem cid183167chemspider159275uniio6pnx53tgkcomptox dashboard (epa)dtxsid70912000 chemical and physical dataformulac25h29no3molar mass391.511 g·mol−13d model (jsmol)interactive image smiles c12cc3(1cc2o)ccc4=c3c=cc(=c4)oc(=o)c5=cc=cc=c5n inchi inchi=1s/c25h29no3/c1-25-13-12-18-17-9-7-16(29-24(28)20-4-2-3-5-22(20)26)14-15(17)6-8-19(18)21(25)10-11-23(25)27/h2-5,7,9,14,18-19,21,23,27h,6,8,10-13,26h2,1h3/t18-,19-,21+,23+,25+/m1/s1key:kzdlyrdwdpobmr-cwwqdxlcsa-n