desmethoxyyangonin desmethoxyyangonin desmethoxyyangonin or 5,6-dehydrokavain is one of the six main kavalactones found in the piper methysticum (kava) plant. desmethoxyyangonin names preferred iupac name 4-methoxy-6--2h-pyran-2-one other names (e)-4-methoxy-6-styryl-2h-pyran-2-one5,6-dehydrokavain4-methoxy-6--2-pyranone identifiers cas number 15345-89-8 y 3d model (jsmol) interactive imageinteractive image chembl chembl254218 y chemspider 4438012 y pubchem cid 5273621 unii f2mbq8qrun y comptox dashboard (epa) dtxsid4033390 inchi inchi=1s/c14h12o3/c1-16-13-9-12(17-14(15)10-13)8-7-11-5-3-2-4-6-11/h2-10h,1h3/b8-7+ ykey: dkkjnzyhgruxbs-bqyqjahwsa-n yinchi=1/c14h12o3/c1-16-13-9-12(17-14(15)10-13)8-7-11-5-3-2-4-6-11/h2-10h,1h3/b8-7+key: dkkjnzyhgruxbs-bqyqjahwbf smiles coc1=cc(=o)oc(=c1)c=cc2=cc=cc=c2o=c/1o\c(=cc(\oc)=c\1)\c=c\c2ccccc2 properties chemical formula c14h12o3 molar mass 228.247 g·mol−1 appearance white to faint yellow powder density 1.18 g/ml melting point 148 °c (298 °f; 421 k) boiling point 440 °c (824 °f; 713 k) except where otherwise noted, data are given for materials in their standard state (at 25 °c , 100 kpa). n verify (what is yn ?) infobox references pharmacology desmethoxyyangonin is a reversible inhibitor of monoamine oxidase b (mao-b). kava is able to increase dopamine levels in the nucleus accumbens and desmethoxyyangonin likely contributes to this effect. this, along with several other catecholamines, may be responsible for the purported attention-promoting effects of kava. unlike the other major kavalactones, desmethoxyyangonin does not appear to act as a gabaa receptor positive allosteric modulator. desmethoxyyangonin has marked activity on the induction of cyp3a23.