5-meo-2-tmt 5-meo-2-tmt 5-methoxy-2,n,n-trimethyltryptamine (5-meo-2,n,n-tmt, 5-meo-tmt) is a psychoactive drug of the tryptamine chemical class which acts as a psychedelic. it was first synthesized by alexander shulgin and reported in his book tihkal ("tryptamines i have known and loved"). 5-meo-tmt is claimed to show psychoactive effects at a dosage of 75–150 mg orally, but these are relatively mild compared to those of other similar compounds. this suggests that while the methyl group on the 2-position of the molecule has impaired the binding of metabolic enzymes like monoamine oxidase (mao), it is also interfering with binding to and/or activation of the serotonin 5-ht2a receptor, the target responsible for mediating the hallucinogenic effects of such compounds. 5-meo-2-tmtlegal statuslegal status de: npsg (industrial and scientific use only) uk: class a identifiers iupac name 2-(5-methoxy-2-methyl-h-indol-3-yl)-n,n-dimethylethanamine cas number67292-68-6pubchem cid49756chemspider45143 yuniixz2ccp18i2chemblchembl7143 ycomptox dashboard (epa)dtxsid10217627 chemical and physical dataformulac14h20n2omolar mass232.327 g·mol−13d model (jsmol)interactive image smiles cc1=c(c2=c(n1)c=cc(=c2)oc)ccn(c)c inchi inchi=1s/c14h20n2o/c1-10-12(7-8-16(2)3)13-9-11(17-4)5-6-14(13)15-10/h5-6,9,15h,7-8h2,1-4h3 ykey:acehbqppddgcgz-uhfffaoysa-n y (verify)