nurse scientist nurse scientist a nurse scientist is a nurse with advanced preparation such as a ph.d. in nursing or related field including research principles and methodology, who also has expert content knowledge in a specific clinical area. the primary focus of the role is to provide leadership in the development, coordination and management of clinical research studies; provide mentorship for nurses in research; lead evaluation activities that improve outcomes for patients participating in research studies; contribute to the overall health sciences literature. nurse scientists have been regarded as knowledge brokers. they participate in nursing research.