adhyperforin adhyperforin adhyperforin is a phytochemical found in the members of the plant genus hypericum including st. john's wort. it has a very similar pharmacological profile to hyperforin and acts as a trpc6 ion channel activator, thereby inhibiting the reuptake of various neurotransmitters including serotonin, norepinephrine, dopamine, gaba, and glutamate. adhyperforin is found in st. john's wort in levels approximately 1/10 those of hyperforin. adhyperforinclinical dataroutes ofadministrationoralatc codenonelegal statuslegal status in general: over-the-counter (otc) identifiers iupac name (1r,5s,6r,7s)-4-hydroxy-6-methyl-5-(2-methylbutanoyl)-1,3,7-tris(3-methyl-2-buten-1-yl)-6-(4-methyl-3-penten-1-yl)bicyclonon-3-ene-2,9-dione cas number143183-63-5 npubchem cid9963735chemspider25066875 nuniiec9k3c78v8chemblchembl388948 ychemical and physical dataformulac36h54o4molar mass550.824 g·mol−13d model (jsmol)interactive image smiles ccc(c)c(=o)c12c(=c(c(=o)c(c1=o)(cc(c2(c)ccc=c(c)c)cc=c(c)c)cc=c(c)c)cc=c(c)c)o inchi inchi=1s/c36h54o4/c1-12-27(10)30(37)36-32(39)29(18-16-25(6)7)31(38)35(33(36)40,21-19-26(8)9)22-28(17-15-24(4)5)34(36,11)20-13-14-23(2)3/h14-16,19,27-28,39h,12-13,17-18,20-22h2,1-11h3/t27?,28-,34+,35+,36-/m0/s1 nkey:dhpdsocoujhghe-acjqspjvsa-n n ny (what is this?) (verify)