sparfloxacin sparfloxacin sparfloxacin is a fluoroquinolone antibiotic used in the treatment of bacterial infections. it has a controversial safety profile. sparfloxacinclinical datapronunciationspar flox a sin trade namesspacin, zagam, othersahfs/drugs.commicromedex detailed consumer informationmedlineplusa600002routes ofadministrationby mouthatc codej01ma09 (who) legal statuslegal status us: ℞-only pharmacokinetic databioavailability92%protein binding45%metabolismhepatic glucuronidation cytochrome p450 system not involvedelimination half-life16 to 30 hoursexcretionfecal (50%) and renal (50%)identifiers iupac name 5-amino-1-cyclopropyl-7--6,8-difluoro-4-oxo-quinoline-3-carboxylic acid cas number110871-86-8 ypubchem cid60464drugbankdb01208 ychemspider54517 yuniiq90aga787lkeggd00590 ychebichebi:9212 ychemblchembl850 ycomptox dashboard (epa)dtxsid9023590 echa infocard100.157.238 chemical and physical dataformulac19h22f2n4o3molar mass392.407 g·mol−13d model (jsmol)interactive imagemelting point266 to 269 °c (511 to 516 °f) (dec.) smiles c1cn(c(n1)c)c2c(c(c3c(c2f)n(cc(c3=o)c(=o)o)c4cc4)n)f inchi inchi=1s/c19h22f2n4o3/c1-8-5-24(6-9(2)23-8)17-13(20)15(22)12-16(14(17)21)25(10-3-4-10)7-11(18(12)26)19(27)28/h7-10,23h,3-6,22h2,1-2h3,(h,27,28)/t8-,9+ ykey:dzzwhbibmuviiw-dtorhvgosa-n y (verify) it was patented in 1985 and approved for medical use in 1993. zagam is no longer available in the united states. medical uses the compound is indicated for treating community-acquired lower respiratory tract infections (acute sinusitis, exacerbations of chronic bronchitis caused by susceptible bacteria, community-acquired pneumonia). adverse reactions