therapy is very small and any side effects are typically only encountered in the first three months of infection. in the long term, the vast majority of clinically infected individuals are asymptomatic, with no significant nutrient loss. in fact, nutrient uptake can be enhanced in some subjects who are hosting a small number of helminths. if the side effects from helminthic therapy were to become unmanageable, they can be alleviated by the use of anti-helminthic medications. the most common clinical symptoms which may be encountered while undergoing helminthic therapy can include: fatigue gastrointestinal discomfort anemia fever abdominal pain weight loss anorexia diarrhea general malaise