mexazolam mexazolam mexazolam (marketed under the trade names melex and sedoxil) is a drug which is a benzodiazepine derivative. mexazolam has been trialed for anxiety and was found to be effective in alleviating anxiety at one week follow-up. mexazolam is metabolised via the cyp3a4 pathway. hmg-coa reductase inhibitors including simvastatin, simvastatin acid, lovastatin, fluvastatin, atorvastatin and cerivastatin inhibit the metabolism of mexazolam, but not the hmg-coa reductase inhibitor pravastatin. its principal active metabolites are chlordesmethyldiazepam (also known as chloronordiazepam or delorazepam, trade name dadumir) and chloroxazepam (also known as lorazepam, trade name ativan). mexazolamclinical datatrade namesmelex, sedoxilother names13-chloro- 2-(2-chlorophenyl)- 5-methyl- 3-oxa- 6,9-diazatricyclo tetradeca- 1(10),11,13-trien- 8-oneahfs/drugs.cominternational drug namesroutes ofadministrationoralatc coden05ba25 (who) legal statuslegal status ca: schedule iv pharmacokinetic datametabolismliver (cyp3a4)excretionkidneyidentifiers iupac name 10-chloro-11b-(2-chlorophenyl)-3-methyl-2,3,5,7-tetrahydro-oxazolobenzodiazepin-6-one cas number31868-18-5pubchem cid4177chemspider4033 yuniis5969b6237keggd01316 ycomptox dashboard (epa)dtxsid9057715 chemical and physical dataformulac18h16cl2n2o2molar mass363.24 g·mol−13d model (jsmol)interactive image smiles clc1ccccc1c42occ(n2cc(=o)nc3c4cc(cl)cc3)c inchi inchi=1s/c18h16cl2n2o2/c1-11-10-24-18(13-4-2-3-5-15(13)20)14-8-12(19)6-7-16(14)21-17(23)9-22(11)18/h2-8,11h,9-10h2,1h3,(h,21,23) ykey:anucdxcticzjrh-uhfffaoysa-n y (verify)