eutropoflavin eutropoflavin eutropoflavin (4'-dimethylamino-7,8-dihydroxyflavone) is a synthetic flavone and selective small-molecule agonist of trkb, the main receptor of brain-derived neurotrophic factor (bdnf), which was derived from structural modification of tropoflavin (7,8-dhf). relative to tropoflavin, eutropoflavin possesses higher agonistic activity at trkb, is significantly more potent than tropoflavin both in vitro and in vivo, and has a longer duration of action (peaking at 4 hours and "partially decaying" at 8~16 hours in rodents). the compound has been found to produce neuroprotective and neurogenic effects in the brain and spinal cord as well as antidepressant-like effects in animals. eutropoflavinclinical dataatc codenoneidentifiers iupac name 2--7,8-dihydroxy-4h-chromen-4-one cas number1205548-04-4pubchem cid44610701chemspider26630138uniib2m862mr4wchemblchembl1800922chemical and physical dataformulac17h15no4molar mass297.310 g·mol−13d model (jsmol)interactive image smiles cn(c)c1ccc(cc1)c2cc(=o)c3ccc(c(c3o2)o)o inchi inchi=inchi=1s/c17h15no4/c1-18(2)11-5-3-10(4-6-11)15-9-14(20)12-7-8-13(19)16(21)17(12)22-15/h3-9,19,21h,1-2h3key:ypayczohgrsgjs-uhfffaoysa-n