epiceram epiceram epiceram (epiceram skin barrier emulsion) is a topical non-steroidal skin cream. based on the research of peter m. elias, it is made up of ceramides, free fatty acids, and cholesterol, and is designed to treat atopic dermatitis, a type of eczema. ceragenix obtained marketing clearance from the u.s. food and drug administration in april 2006. this prescription medical device works as a moisturizer and barrier cream. in the us, it requires prescription and was launched in october 2008 by promius pharma. epiceram was acquired by puracap pharmaceutical llc in 2010. epiceram obtained health canada medical device license in september 2009 and was launched by pediapharm in november of the same year. it is sold under prescription.