d-deprenyl d-deprenyl d-deprenyl, also known as or dextro-n-propargyl-n-methylamphetamine, is an mao-b inhibitor that metabolizes into d-amphetamine and d-methamphetamine and is therefore also a norepinephrine–dopamine releasing agent. it is the opposite enantiomer of l-deprenyl (selegiline). d-deprenylidentifiers iupac name (2s)-n-methyl-1-phenyl-n-prop-2-ynyl-propan-2-amine cas number4528-51-2 ypubchem cid199605chemspider172774 nuniiyk7hy2ry1wchemical and physical dataformulac13h17nmolar mass187.286 g·mol−13d model (jsmol)interactive image smiles c#ccn((cc1ccccc1)c)c inchi inchi=1s/c13h17n/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13/h1,5-9,12h,10-11h2,2-3h3/t12-/m0/s1 nkey:mezlkoacvspner-lbprgkrzsa-n n ny (what is this?) (verify) l-deprenyl, also an mao-b inhibitor, metabolizes to l-amphetamine and l-methamphetamine, which are both norepinephrine releasing agents. in contrast, d-deprenyl additionally has dopaminergic effects and has been found to be reinforcing in scientific research, whereas l-deprenyl is not known to have any appreciable psychological reinforcement. in addition to its actions as an mao-b inhibitor and ndra, d-deprenyl has been found to bind with high affinity to the σ1 receptor (ki = 79 nm) similarly to various other amphetamine derivatives. its l-isomer, selegiline, binds with 3.5-fold lower affinity in comparison.