zavegepant zavegepant zavegepant, sold under the brand name zavzpret, is a medication used for the treatment of migraine. zavegepant is a calcitonin gene-related peptide receptor antagonist. it is sprayed into the nose. it is sold by pfizer. zavegepantclinical datatrade nameszavzpretother namesbhv-3500license data us dailymed: zavegepant routes ofadministrationnasaldrug classcalcitonin gene-related peptide receptor antagonistatc codenonelegal statuslegal status us: ℞-only identifiers iupac name n--1-oxopropan-2-yl]-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide cas number1337918-83-8as hcl: 1414976-20-7pubchem cid53472683as hcl: 134819878drugbankdb15688chemspider30814207uniiodu3zaz94jas hcl: 000qcm6halkeggd11898as hcl: d11899chemblchembl2397415as hcl: chembl4650220chemical and physical dataformulac36h46n8o3molar mass638.817 g·mol−13d model (jsmol)interactive image smiles cc1=cc(=cc2=c1nn=c2)cc(c(=o)n3ccn(cc3)c4ccn(cc4)c)nc(=o)n5ccc(cc5)c6=cc7=cc=cc=c7nc6=o inchi inchi=1s/c36h46n8o3/c1-24-19-25(20-28-23-37-40-33(24)28)21-32(35(46)43-17-15-42(16-18-43)29-9-11-41(2)12-10-29)39-36(47)44-13-7-26(8-14-44)30-22-27-5-3-4-6-31(27)38-34(30)45/h3-6,19-20,22-23,26,29,32h,7-18,21h2,1-2h3,(h,37,40)(h,38,45)(h,39,47)/t32-/m1/s1key:jjvaphyeozskjz-jgcgqsqusa-nkey:vqduwcsspsosna-rywngcacsa-n the most common adverse reactions include taste disorders, nausea, nasal discomfort, and vomiting. zavegepant was approved for medical use in the united states in march 2023. medical uses zavegepant is indicated for the acute treatment of migraine with or without aura in adults.