senicapoc senicapoc senicapoc (ica-17043) is a gardos channel blocker. senicapoc names preferred iupac name 2,2-bis(4-fluorophenyl)-2-phenylacetamide identifiers cas number 289656-45-7 y 3d model (jsmol) interactive image chemspider 187516 n iuphar/bps 2331 kegg d06640 y pubchem cid 216327 unii ts6g201a6q y comptox dashboard (epa) dtxsid60276906 inchi inchi=1s/c20h15f2no/c21-17-10-6-15(7-11-17)20(19(23)24,14-4-2-1-3-5-14)16-8-12-18(22)13-9-16/h1-13h,(h2,23,24) nkey: sctzuztyrmomkt-uhfffaoysa-n ninchi=1/c20h15f2no/c21-17-10-6-15(7-11-17)20(19(23)24,14-4-2-1-3-5-14)16-8-12-18(22)13-9-16/h1-13h,(h2,23,24)key: sctzuztyrmomkt-uhfffaoyar smiles c1=cc=c(c=c1)c(c2=cc=c(c=c2)f)(c3=cc=c(c=c3)f)c(=o)n properties chemical formula c20h15f2no molar mass 323.34 g/mol except where otherwise noted, data are given for materials in their standard state (at 25 °c , 100 kpa). n verify (what is yn ?) infobox references it has been proposed for use in sickle cell anemia. gardos channel blockers may work in the treatment of sickle cell anemia by blocking the efflux of potassium and water from red blood cells, thereby preventing the dehydration of red blood cells and stopping the polymerization of hbs. the gardos channel has been identified as kcnn4. the "ica" is for icagen, which is developing the drug.