pyrrocaine pyrrocaine pyrrocaine is a local anesthetic drug. the cogency of pyrrocaine is equivalent to lidocaine in blocking the motor nerve and sensory. pyrrocaine was proven to be somewhat harmless compared to lidocaine. no signs of methemoglobinemia was found while observing. it was considered unsafe for acute porphyria treatment. no evidence is found that it is profitly used now. pyrrocaine names preferred iupac name n-(2,6-dimethylphenyl)-2-(pyrrolidin-1-yl)acetamide identifiers cas number 2210-77-7 3d model (jsmol) interactive image chembl chembl1895219 chemspider 22776 ec number 218-642-7 kegg d05665 pubchem cid 24361 unii 9d47l94cpw comptox dashboard (epa) dtxsid9046150 inchi inchi=1s/c14h20n2o/c1-11-6-5-7-12(2)14(11)15-13(17)10-16-8-3-4-9-16/h5-7h,3-4,8-10h2,1-2h3,(h,15,17)key: oycgkeckivyhtn-uhfffaoysa-n smiles cc1cccc(c1nc(=o)cn2cccc2)c properties chemical formula c14h20n2o molar mass 232.327 except where otherwise noted, data are given for materials in their standard state (at 25 °c , 100 kpa). infobox references history in the 1960s it was most of the time used as a nerve blocker dental anesthetic and dentists recommended it due to its fast commencement. adverse effects pyrrocane has very similar side effects on blood pressure and heart rate compared to lidocaine. synthesis selfsame as lidocaine, albeit interposing pyrrolidine for diethylamine. synthesis: patents: amide formation between 2,6-dimethylaniline (1) and chloroacetyl chloride (2) gives (3). displacement of the remaining halogen by pyrrolidine (4) completed the synthesis of pyrrocaine (5).