2β-propanoyl-3β-(4-tolyl)-tropane 2β-propanoyl-3β-(4-tolyl)-tropane 2β-propanoyl-3β-(4-tolyl)tropane also known as wf-11 or 2-ptt is a cocaine analogue 20 times more potent than cocaine at binding to the dopamine transporter with increased selectivity for the norepinephrine transporters. it also shows marked increase in metabolic stability. in contrast to the findings of cocaine effects, wf-11 has been shown to produce a uniform downregulation of tyrosine hydroxylase protein and activity gene expression with a regimen of use. 2β-propanoyl-3β-(4-tolyl)-tropaneidentifiers iupac name 1-octan-2-yl]propan-1-one cas number152783-29-4pubchem cid127862chemspider113404comptox dashboard (epa)dtxsid60934599 chemical and physical dataformulac18h25nomolar mass271.404 g·mol−13d model (jsmol)interactive image smiles ccc(=o)12cc(n2c)c1c3=cc=c(c=c3)c inchi inchi=1s/c18h25no/c1-4-17(20)18-15(13-7-5-12(2)6-8-13)11-14-9-10-16(18)19(14)3/h5-8,14-16,18h,4,9-11h2,1-3h3/t14-,15+,16+,18-/m0/s1key:pzeajtavrylbtk-lhhmisfzsa-n