postarthroscopic glenohumeral chondrolysis postarthroscopic glenohumeral chondrolysis postarthroscopic glenohumeral chondrolysis (pagcl) is a rare complication of arthroscopic surgery and involves chondrolysis wherein the articular cartilage of the shoulder undergoes rapid, degenerative changes shortly after arthroscopic surgery. postarthroscopic glenohumeral chondrolysishuman shoulder(joint)specialtyorthopedicrisk factorscomplication of arthroscopic surgery causes bupivacaine, lidocaine, ropivacaine and levobupivacaine are all toxic to cartilage and their intra-articular infusions can lead to this toxic effect. intra-articular pain pumps with local anesthetics have been implicated as a potential cause. diagnosis treatment total joint arthroplasty or reverse total joint arthroplasty (shoulder replacement surgery)