tomatoes that have undergone agrobacterium mediated nuclear transformation. additionally, rabbits were orally immunized with an edible vaccine for bovine pneumonic pasteurellosis, and there was a positive response. while those were two specific studies, generally speaking, research using mice models are being conducted to treat cholera and type 1 diabetes. availability while the public awareness regarding edible vaccines is increasing, they are still not available for consumer use. currently, they have only developed and started testing edible vaccines for some diseases. during three of the recent disease outbreaks around the world, edible vaccines have been developed for testing on animals but have not reached human trials. also, it has been found that a biotechnological company has started to develop a patent and are working on beginning clinical trials for a transmissible gastroenteritis virus.