sh-i-048a sh-i-048a sh-i-048a (sh-i-048a) is a benzodiazepine derivative related in structure to compounds such as flubromazepam and meclonazepam. sh-i-048a is described as a non subtype selective superagonist at the benzodiazepine site of gabaa receptors, with a binding affinity of 0.77nm at the α1 subtype, 0.17nm at α2, 0.38nm at α3 and 0.11nm at α5. it has been used to study the functional differences between the different subtypes of the gabaa receptor. sh-i-048alegal statuslegal status ca: schedule iv de: npsg (industrial and scientific use only) uk: under psychoactive substances act identifiers iupac name (3s)-7-bromo-5-(2-fluorophenyl)-3-methyl-1h-benzo diazepin-2(3h)-one cas number872874-11-8 ypubchem cid49850464chemspider57381614uniikn27p6csu9chemical and physical dataformulac16h12brfn2omolar mass347.187 g·mol−13d model (jsmol)interactive image smiles fc3ccccc3c2=n(c)c(=o)nc1ccc(br)cc12 inchi inchi=1s/c16h12brfn2o/c1-9-16(21)20-14-7-6-10(17)8-12(14)15(19-9)11-4-2-3-5-13(11)18/h2-9h,1h3,(h,20,21)/t9-/m0/s1key:qefzckuxgldppt-vifpvbqesa-n