wy-46824 wy-46824 wy-46824 is a norepinephrine-dopamine reuptake inhibitor related to venlafaxine that was disclosed by paige mahaney, et al. of wyeth in 2008. the compound actually appears in an article a year earlier in 2007 but is not the main focus of the work. it has net binding of 46 nm, dat = 58 nm and sert = 18795 nm. the racemic compound was resolved into its constituent enantiomers, and the (s) enantiomer is the more active one. the n-desmethyl derivative shows similar activity. wy-46824identifiers iupac name 1-cyclohexan-1-ol cas number122718-49-4 ypubchem cid10314993chemspider8490458unii99t4hmn9hvchemblchembl511347comptox dashboard (epa)dtxsid50438031 chemical and physical dataformulac19h29cln2omolar mass336.90 g·mol−13d model (jsmol)interactive image smiles cn1ccn(cc1)cc(c2=cc(=cc=c2)cl)c3(ccccc3)o inchi inchi=1s/c19h29cln2o/c1-21-10-12-22(13-11-21)15-18(16-6-5-7-17(20)14-16)19(23)8-3-2-4-9-19/h5-7,14,18,23h,2-4,8-13,15h2,1h3key:gruiiaqnnwqjpw-uhfffaoysa-n