ayazi syndrome ayazi syndrome ayazi syndrome (or chromosome 21 xq21 deletion syndrome) is a syndrome characterized by choroideremia, congenital deafness and obesity. ayazi syndromeother nameschoroideremia-deafness-obesity syndromethis condition is inherited in an x-linked recessive manner signs and symptoms the presentation for this condition is as follows: mental retardation deafness at birth obesity choroideremia impaired vision progressive degeneration of the choroid genetics ayazi syndrome's inheritance pattern is described as x-linked recessive. genes known to be deleted are chm and pou3f4, both located on the xq21 locus. diagnosis