streptomyces venezuelae streptomyces venezuelae streptomyces venezuelae is a species of soil-dwelling gram-positive bacterium of the genus streptomyces. s. venezuelae is filamentous. in its spore-bearing stage, hyphae perfuse both above ground as aerial hyphae and in the soil substrate. chloramphenicol, the first antibiotic to be manufactured synthetically on a large scale, was originally derived from s. venezuelae. other secondary metabolites produced by s. venezuelae include jadomycin and pikromycin. streptomyces venezuelae scientific classification domain: bacteria phylum: actinomycetota class: actinomycetia order: streptomycetales family: streptomycetaceae genus: streptomyces species: s. venezuelae binomial name streptomyces venezuelaeehrlich 1948