acyline acyline acyline (developmental code name mer-104) is a gonadotropin-releasing hormone analogue (gnrh analogue) and gonadotropin-releasing hormone antagonist (gnrh antagonist) which was never marketed. it has been shown to suppress gonadotropin and testosterone levels in men. acyline is a peptide and under normal circumstances is not orally active. for this reason, it has instead been administered by subcutaneous injection. acylineclinical dataother namesmer-104routes ofadministrationsubcutaneous injectiondrug classgnrh antagonistidentifiers iupac name (2s)-1-amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-3-hydroxypropanoyl]amino]-3-(4-acetamidophenyl)propanoyl]amino]-3-(4-acetamidophenyl)propanoyl]amino]-4-methylpentanoyl]amino]-6-(propan-2-ylamino)hexanoyl]-n-pyrrolidine-2-carboxamide cas number170157-13-8pubchem cid16137348drugbankdb11906chemspider17293858uniis3439d3b35chemblchembl262747comptox dashboard (epa)dtxsid60168812 chemical and physical dataformulac80h102cln15o14molar mass1533.24 g·mol−13d model (jsmol)interactive image smiles c(c(=o)n)nc(=o)1cccn1c(=o)(ccccnc(c)c)nc(=o)(cc(c)c)nc(=o)(cc2=cc=c(c=c2)nc(=o)c)nc(=o)(cc3=cc=c(c=c3)nc(=o)c)nc(=o)(co)nc(=o)(cc4=cn=cc=c4)nc(=o)(cc5=cc=c(c=c5)cl)nc(=o)(cc6=cc7=cc=cc=c7c=c6)nc(=o)c inchi inchi=1s/c80h102cln15o14/c1-46(2)37-63(72(102)89-62(18-11-12-35-84-47(3)4)80(110)96-36-14-19-70(96)79(109)85-48(5)71(82)101)90-74(104)66(40-53-23-30-60(31-24-53)86-49(6)98)92-76(106)67(41-54-25-32-61(33-26-54)87-50(7)99)94-78(108)69(45-97)95-77(107)68(43-56-15-13-34-83-44-56)93-75(105)65(39-52-21-28-59(81)29-22-52)91-73(103)64(88-51(8)100)42-55-20-27-57-16-9-10-17-58(57)38-55/h9-10,13,15-17,20-34,38,44,46-48,62-70,84,97h,11-12,14,18-19,35-37,39-43,45h2,1-8h3,(h2,82,101)(h,85,109)(h,86,98)(h,87,99)(h,88,100)(h,89,102)(h,90,104)(h,91,103)(h,92,106)(h,93,105)(h,94,108)(h,95,107)/t48-,62+,63+,64-,65-,66-,67+,68-,69+,70+/m1/s1key:zwnuqdjanzgvfo-yhsalvgysa-n