flavonoid alkaloid flavonoid alkaloid a flavonoid alkaloid also known as a flavoalkaloid is a type of natural product produced by plants that contains both a flavonoid core structure and a nitrogen containing substituent so that the substance is also classified as an alkaloid. the most common flavonoid alkaloids contain a nitrogen heterocycle such as a pyridine or piperidine which is covalently bonded to the a-ring of a chromone. one flavonoid alkaloid, lilaline, was isolated from lilium candidum in 1987. the synthesis of flavonoid alkaloids has been achieved pharmacology a number of flavonoid alkaloids have been discovered that possess diverse pharmacological activity that may have application in the treatment of a range of diseases. one example is alvocidib, a potent cdk9 kinase inhibitor that is being developed for the treatment of chronic lymphocytic leukemia (cll) and acute myeloid leukemia (aml). flavonoid alkaloids were also found to present alpha-glucosidase inhibitory activity through artificial organic synthesis.