ozarelix ozarelix ozarelix (developmental code names d-63153, spi-153) is a peptide gonadotropin-releasing hormone antagonist (gnrh antagonist) which is or was under development by aeterna zentaris inc. and spectrum pharmaceuticals as a long-acting injection formulation for the treatment of prostate cancer. it has also been investigated for the treatment of endometriosis, but no development has been reported. the drug was previously under investigation for the treatment of benign prostatic hyperplasia and alzheimer's disease as well, but development for these indications was discontinued. as of june 2015, it was in phase ii clinical trials for prostate cancer. it seems to no longer be under development. ozarelixclinical dataother namesd-63153; spi-153routes ofadministrationinjectiondrug classgnrh modulator; gnrh antagonist; antigonadotropinidentifiers iupac name (2s)-1-amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-3-hydroxypropanoyl]-methylamino]-3-(4-hydroxyphenyl)propanoyl]amino]-6-(carbamoylamino)hexanoyl]amino]hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-n-pyrrolidine-2-carboxamide cas number295350-45-7 896710-46-6 (acetate)pubchem cid25080293drugbankdb12581chemspider17291594uniiq1if8m2yl3comptox dashboard (epa)dtxsid60183722 echa infocard100.232.650 chemical and physical dataformulac72h96cln17o14molar mass1459.12 g·mol−13d model (jsmol)interactive image smiles cccc(c(=o)n(cccn=c(n)n)c(=o)n1ccc1c(=o)n(c)c(=o)n)nc(=o)(ccccnc(=o)n)nc(=o)(cc2=cc=c(c=c2)o)n(c)c(=o)(co)nc(=o)(cc3=cn=cc=c3)nc(=o)(cc4=cc=c(c=c4)cl)nc(=o)(cc5=cc6=cc=cc=c6c=c5)nc(=o)c inchi inchi=1s/c72h96cln17o14/c1-5-6-17-52(63(96)85-54(19-12-33-79-71(75)76)70(103)90-34-13-20-59(90)67(100)81-42(2)61(74)94)83-62(95)53(18-9-10-32-80-72(77)104)84-68(101)60(39-45-24-29-51(93)30-25-45)89(4)69(102)58(41-91)88-66(99)57(38-47-14-11-31-78-40-47)87-65(98)56(36-44-22-27-50(73)28-23-44)86-64(97)55(82-43(3)92)37-46-21-26-48-15-7-8-16-49(48)35-46/h7-8,11,14-16,21-31,35,40,42,52-60,91,93h,5-6,9-10,12-13,17-20,32-34,36-39,41h2,1-4h3,(h2,74,94)(h,81,100)(h,82,92)(h,83,95)(h,84,101)(h,85,96)(h,86,97)(h,87,98)(h,88,99)(h4,75,76,79)(h3,77,80,104)/t42-,52+,53-,54+,55-,56-,57-,58+,59+,60+/m1/s1key:katzuzntrinhdt-halmfytrsa-n