toxiferine toxiferine toxiferine (c-toxiferine i) is a curare toxin. it is a bisindole alkaloid derived from strychnos toxifera and a nicotinic acetylcholine receptor antagonist. this alkaloid is the main toxic component of calabash curare, and one of the most toxic plant alkaloids known. the lethal dose (ld50) for mice has been determined as 10 - 60 µg/kg by intravenous administration. it is a muscle relaxant that causes paralysis of skeletal muscle, which takes approximately 2 hours to recovery for a moderate dose, and 8 hours of total paralysis with a 20-fold paralytic dose. the paralysis can be antagonized by neostigmine toxiferineidentifierscas number302-30-7pubchem cid5281411chemspider4444760unii9m7d9k3ojichemblchembl231047comptox dashboard (epa)dtxsid30897243 chemical and physical dataformulac40h46n4o2molar mass614.834 g·mol−13d model (jsmol)interactive image smiles 123(cc2(c)c/c4=c/co)5()n(c6=c3c=cc=c6)/c=c7(8(cc9(c)c/%10)9()c\7()c%10=c/co)()n(c%11=c8c=cc=c%11)/c=c5/4()c1