dienestrol dienestrol dienestrol (inn, usan) (brand names ortho dienestrol, dienoestrol, dienoestrol ortho, sexadien, denestrolin, dienol, dinovex, follormon, oestrodiene, synestrol, numerous others), also known as dienoestrol (ban), is a synthetic nonsteroidal estrogen of the stilbestrol group which is or was used to treat menopausal symptoms in the united states and europe. it has been studied for use by rectal administration in the treatment of prostate cancer in men as well. the medication was introduced in the u.s. in 1947 by schering as synestrol and in france in 1948 as cycladiene. dienestrol is a close analogue of diethylstilbestrol. it has approximately 223% and 404% of the affinity of estradiol at the erα and erβ, respectively. dienestrolclinical datatrade namesortho dienestrol, dienoestrol, dienoestrol ortho, sexadien, cycladiene, denestrolin, dienol, dinovex, follormon, oestrodiene, synestrolother namesdienoestrol; p-phenol; 3,4-di(para-hydroxyphenyl)-2,4-hexadieneahfs/drugs.commicromedex detailed consumer informationdrug classnonsteroidal estrogenatc codeg03cb01 (who) g03cc02 (who)identifiers iupac name 4-phenol cas number13029-44-2 npubchem cid667476iuphar/bps7160drugbankdb00890 ychemspider580857 yuniirrw32x4u1fkeggd00898 ychebichebi:4518 nchemblchembl1018 yecha infocard100.001.381 chemical and physical dataformulac18h18o2molar mass266.340 g·mol−13d model (jsmol)interactive image smiles oc2ccc(c(/c(c1ccc(o)cc1)=c/c)=c\c)cc2 inchi inchi=1s/c18h18o2/c1-3-17(13-5-9-15(19)10-6-13)18(4-2)14-7-11-16(20)12-8-14/h3-12,19-20h,1-2h3/b17-3+,18-4+ ykey:nfdfqcuyfhcnbw-scgpfsfssa-n y ny (what is this?) (verify) dienestrol diacetate (brand names faragynol, gynocyrol, others) also exists and has been used medically. isomers dienestrol (unspecified) - cas 84-17-3 e,e-dienestrol - cas 13029-44-2 z,z-dienestrol - cas 35495-11-5