vofopitant vofopitant vofopitant (gr205171) is a drug which acts as an nk1 receptor antagonist. it has antiemetic effects as with other nk1 antagonists, and also shows anxiolytic actions in animals. it was studied for applications such as the treatment of social phobia and post-traumatic stress disorder, but did not prove sufficiently effective to be marketed. vofopitantclinical dataother namesgr205171; gr-205171routes ofadministrationoralatc codenoneidentifiers iupac name (2s,3s)-n-phenyl)methyl]-2-phenylpiperidin-3-amine cas number168266-90-8pubchem cid6918331iuphar/bps5752chemspider5293535uniik08bk043yschemical and physical dataformulac21h23f3n6omolar mass432.451 g·mol−13d model (jsmol)interactive image smiles coc1=c(c=c(c=c1)n2c(=nn=n2)c(f)(f)f)cn3cccn3c4=cc=cc=c4 inchi inchi=1s/c21h23f3n6o/c1-31-18-10-9-16(30-20(21(22,23)24)27-28-29-30)12-15(18)13-26-17-8-5-11-25-19(17)14-6-3-2-4-7-14/h2-4,6-7,9-10,12,17,19,25-26h,5,8,11,13h2,1h3/t17-,19-/m0/s1key:xilnrortjvdyrh-hkuynngssa-n