emdt emdt 2-ethyl-5-methoxy-n,n-dimethyltryptamine (emdt) is a tryptamine derivative which is used in scientific research. it acts as a selective 5-ht6 receptor agonist, with a ki of 16 nm, and was one of the first selective agonists developed for this receptor. emdt inhibits both short- and long-term memory formation in animal studies, and this effect can be reversed by the selective 5-ht6 antagonist sb-399,885. additionally, it is active in the tail suspension test, suggesting that it could be an effective antidepressant. emdtclinical dataatc codenoneidentifiers iupac name 2-(2-ethyl-5-methoxy-1h-indol-3-yl)-n,n-dimethylethanamine cas number263744-72-5 ypubchem cid6918513iuphar/bps12chemspider5293710 nchemblchembl267615chemical and physical dataformulac15h22n2omolar mass246.354 g·mol−13d model (jsmol)interactive image smiles ccc2c1ccc(oc)cc1c2ccn(c)c inchi inchi=1s/c15h22n2o/c1-5-14-12(8-9-17(2)3)13-10-11(18-4)6-7-15(13)16-14/h6-7,10,16h,5,8-9h2,1-4h3 nkey:zeyrdxuwjdgtld-uhfffaoysa-n n ny (what is this?) (verify)