congenital hemolytic anemia congenital hemolytic anemia congenital hemolytic anemia refers to hemolytic anemia which is primarily due to congenital disorders. congenital hemolytic anemiaother nameshereditary hemolytic anemiaspecialtyhematology types basically classified by causative mechanism, types of congenital hemolytic anemia include: genetic conditions of rbc membrane hereditary spherocytosis hereditary elliptocytosis genetic conditions of rbc metabolism (enzyme defects). this group is sometimes called congenital nonspherocytic (hemolytic) anemia, which is a term for a congenital hemolytic anemia without spherocytosis, and usually excluding hemoglobin abnormalities as well, but rather encompassing defects of glycolysis in the erythrocyte. glucose-6-phosphate dehydrogenase deficiency (g6pd or favism) pyruvate kinase deficiency aldolase a deficiency hemoglobinopathies/genetic conditions of hemoglobin sickle cell anemia congenital dyserythropoietic anemia thalassemia