oxycholesterol oxycholesterol oxycholesterol or 5,6-epoxycholesterol is a form of oxidized cholesterol implicated in atherosclerosis. it is commonly formed from the reaction of fats and oxygen during high temperature cooking such as frying. oxycholesterol names iupac name 5,6β-epoxy-5β-cholestan-3β-ol systematic iupac name (3s,4as,5ar,6as,6bs,9r,9ar,11as,11br)-9a,11b-dimethyl-9-hexadecahydrocyclopentaphenanthrooxiren-3-ol identifiers cas number 4025-59-6 y 3d model (jsmol) interactive image chemspider 97204 pubchem cid 108109 unii pfd65a4x36 y inchi inchi=1s/c27h46o2/c1-17(2)7-6-8-18(3)21-9-10-22-20-15-24-27(29-24)16-19(28)11-14-26(27,5)23(20)12-13-25(21,22)4/h17-24,28h,6-16h2,1-5h3/t18-,19+,20+,21-,22+,23+,24-,25-,26-,27-/m1/s1key: pryijagaejzdbo-dtlxenbrsa-ninchi=1/c27h46o2/c1-17(2)7-6-8-18(3)21-9-10-22-20-15-24-27(29-24)16-19(28)11-14-26(27,5)23(20)12-13-25(21,22)4/h17-24,28h,6-16h2,1-5h3/t18-,19+,20+,21-,22+,23+,24-,25-,26-,27-/m1/s1key: pryijagaejzdbo-dtlxenbrbq smiles c(cccc(c)c)1cc21(cc32c45(3(cc(c5)o)c)o4)c properties chemical formula c27h46o2 molar mass 402.663 g·mol−1 except where otherwise noted, data are given for materials in their standard state (at 25 °c , 100 kpa). infobox references in a study about the effects of oxycholesterol in rabbits with induced hypercholesterolemia, it was shown that compared feeding rabbits cholesterol and unoxidized cholesterol, feeding rabbits oxycholesterol resulted in their developing much higher levels of total cholesterol and low density lipoprotein cholesterol. it is also shown to increase the amount of homocysteine and asymmetric dimethylarginine levels in the rabbits. an abundance of homocysteine leads to an organism with greater chances of endothelial cell injury which can then lead to coronary artery disease. asymmetric dimethylarginine is shown to cause adverse effects on humans in the form of cardiovascular and metabolic diseases. therefore it was concluded that adding oxycholesterol into diets of animals with hypercholesterolemia increases endothelial dysfunction and inflammatory response.