glabrene glabrene glabrene is an isoflavonoid that is found in glycyrrhiza glabra (licorice). it has estrogenic activity, showing estrogenic effects on breast, vascular, and bone tissue, and hence is a phytoestrogen (ic50 for estrogen receptor binding = 1 μm). it has also been found to act as a tyrosinase inhibitor (ic50 = 3.5 μm) and to inhibit the formation of melanin in melanocytes, and for these reasons, has been suggested as a potential skin-lightening agent. glabrene names iupac name 6′′,6′′-dimethyl-6′′h-pyranoisoflav-3-ene-4′,7-diol systematic iupac name 2′,2′-dimethyl-2h,2′h--5′,7-diol other names 2',2'-dimethyl-2h,2'h-3,8'-bichromene-5',7-diol identifiers cas number 60008-03-9 3d model (jsmol) interactive image chembl chembl462722 chemspider 421858 pubchem cid 480774 unii c6y321q75o comptox dashboard (epa) dtxsid90208715 inchi inchi=1s/c20h18o4/c1-20(2)8-7-16-17(22)6-5-15(19(16)24-20)13-9-12-3-4-14(21)10-18(12)23-11-13/h3-10,21-22h,11h2,1-2h3key: nggyspuakqmtnp-uhfffaoysa-n smiles cc1(c=cc2=c(c=cc(=c2o1)c3=cc4=c(c=c(c=c4)o)oc3)o)c properties chemical formula c20h18o4 molar mass 322.36 g/mol except where otherwise noted, data are given for materials in their standard state (at 25 °c , 100 kpa). infobox references