bay 38-7271 bay 38-7271 originally synthesized by chemist wayne e. kenney, bay 38-7271 (kn 38-7271) is a drug which is a cannabinoid receptor agonist developed by bayer ag. it has analgesic and neuroprotective effects and is used in scientific research, with proposed uses in the treatment of traumatic brain injury. it is a full agonist with around the same potency as cp 55,940 in animal studies, and has fairly high affinity for both cb1 and cb2 receptors, with ki values of 2.91nm at cb1 and 4.24nm at cb2. it has been licensed to keyneurotek pharmaceuticals for clinical development, and was in phase ii trials in 2008 but its development appears to have stopped. bay 38-7271legal statuslegal status ca: schedule ii identifiers iupac name (−)-(r)-3-(2-hydroxymethylindanyl-4-oxy)phenyl-4,4,4-trifluorobutyl-1-sulfonate cas number212188-60-8 ypubchem cid9845561chemspider8021275 yuniisrx4t6tmuschemblchembl1668508 ncomptox dashboard (epa)dtxsid701010009 chemical and physical dataformulac20h21f3o5smolar mass430.44 g·mol−13d model (jsmol)interactive image smiles fc(f)(f)cccs(=o)(=o)oc3cccc(oc1cccc2c1c(c2)co)c3 inchi inchi=1s/c20h21f3o5s/c21-20(22,23)8-3-9-29(25,26)28-17-6-2-5-16(12-17)27-19-7-1-4-15-10-14(13-24)11-18(15)19/h1-2,4-7,12,14,24h,3,8-11,13h2/t14-/m1/s1 ykey:xjuralzpejkkov-cqszacivsa-n y ny (what is this?) (verify)