tropanserin tropanserin tropanserin (inn; mdl-72,422) is a drug which acts as a potent and selective 5-ht3 receptor antagonist. it was investigated in clinical trials for the treatment of migraine in the 1980s but was never marketed. not to be confused with tropisetron. tropanserinclinical dataatc codenoneidentifiers iupac name octan-3-yl] 3,5-dimethylbenzoate cas number85181-40-4 85181-38-0 (hcl)pubchem cid68600chemspider19969918unii04b48i6vhrcomptox dashboard (epa)dtxsid0042618 chemical and physical dataformulac17h23no2molar mass273.376 g·mol−13d model (jsmol)interactive image smiles cn31cc3c(c1)oc(=o)c2cc(c)cc(c)c2 inchi inchi=1s/c17h23no2/c1-11-6-12(2)8-13(7-11)17(19)20-16-9-14-4-5-15(10-16)18(14)3/h6-8,14-16h,4-5,9-10h2,1-3h3/t14-,15+,16+key:hddnyflpwfsbln-zshcynchsa-n synthesis tropanserin can be prepared by the reaction of tropine with 3,5-dimethylbenzoyl chloride. tropanserin synthesis