hepatoerythropoietic porphyria hepatoerythropoietic porphyria hepatoerythropoietic porphyria is a very rare form of hepatic porphyria caused by a disorder in both genes which code uroporphyrinogen iii decarboxylase (urod).: 525 hepatoerythropoietic porphyriaother nameshepurod drawn from pdb: 1uro​.specialtydermatology, gastroenterology, medical genetics, endocrinology it has a similar presentation to porphyria cutanea tarda (pct), but with earlier onset. in classifications which define pct type 1 as "sporadic" and pct type 2 as "familial", hepatoerythropoietic porphyria is more similar to type 2.