– manny is driven to madness and totally ransacks the area outside the shop, before using a hot water bottle as a loincloth, grabbing a flaming torch and painting "eat me" on his stomach, whilst jumping on the roof of an abandoned car. bernard dismisses it as "attention-seeking rubbish" throughout the episode. deep space disorder planetes a condition which is known to affect hachirota "hachimaki" hoshino after an accident in lunar orbit, on the dark side of the moon, during a solar storm which left him isolated in complete darkness. he is retrieved with negligible physical effects, but is diagnosed with deep space disorder, a mental disorder that can cripple an eva astronaut with severe hallucinations. dermatemeculitis drake & josh a skin disease that causes the hands and feet of the body to turn a sickly green color. this can usually only be cured by a series of painful injections. a rumored alternate cure is to soak the hands and feet in buckets of a substance called zypholic acid, which can be found in lizard urine. the hands and feet must be soaked for no less than 45 minutes. megan tricks drake into thinking he has this disease because he ate a cookie that was hers, and later states, "you know, there's another cure: next time, don't eat my big cookie." desperation disease eureka 7 a disease that strikes randomly and has no known vector of contagion. individuals gradually become detached from the world until they are completely catatonic. the name of the disease does not come from the victims' state, who seem to be communing with something metaphysical, but rather, from their families who despair of trying to wake them. dark gundam cells mobile fighter g gundam nanomachines from the devil gundam (dark gundam in north american dub) infect living organisms and undergo mitosis, allowing the devil gundam to control the victim. the victim will gain super-strength and self-recovery abilities and if inside a mobile fighter, will spread the cells to the mobile fighter and give it the abilities of the devil gundam, often mutating the mobile fighter into a stronger robot. if the cells have not reached the brain, the victim can be cured. diminished gluteal syndrome (dgs) king of the hill a fictional genetic disorder characterized by a person being born without buttocks, forcing them to sit on their tailbone and cause pain in their back. the disease has no cure or treatment, although fake saline buttocks are able to relieve pain caused by sitting on the spine. double prison plague (shackelitis) hogan's heroes episode: the prisoner's prisoner a fictional disease invented by colonel hogan. in the early stages, the victim's neck will swell but the victim will not feel any different. in the second stage, the victim's body heat will go up dramatically, followed by loss of movement in the legs and furious chills. drafa plague babylon 5 destroys cells that produce neurotransmitters in the synaptic gap, thus inhibiting nerve signals from the brain to the rest of the body. without such signals from the brain, the organs lose their ability to function correctly, much like als in humans. it is only contagious among those alien species which used specialized cells to produce neurotransmitters, and among these species, it is 100% terminal within 24 hours of the onset of symptoms. initial symptoms include dizziness, numbness & tingling in the extremities, sore throat, followed by progressively worsening ascending paralysis, euphoria, memory issues, then death. fortunately for most of the other sentient races in babylon 5, their lack of such specialized neurotransmitter cells render them immune to the disease, save for the pak'ma'ra, whose green cells were similar enough to the markab yellow cells that a pak'ma'ra died of it on the station. the disease caused the markab to go extinct. similar to the black death and hiv/aids among humans, the drafa plague bears a stigma among the markab as a disease that the public felt was only caught by those considered sinful, immoral or unclean by markab standards, and a punishment by their gods for committing such acts. the disease was named after an island on their homeworld where its inhabitants were wiped out by the disease, an island noted in markab history for its decadence and immorality. the story of the island was eventually used to frighten small markab children into behaving. even accusing a markab of being infected with the disease can bring shame, paranoia, fear, and an angry response from the accused, and markab doctors would frequently certify someone's death from the disease as death by natural causes, so the family could avoid a scandal and the implied accusation that they or their family were unclean or immoral. ecola spaceballs: the animated series e. coli and ebola injected into a carbonated drink, creating a "deadly soda that will kill our enemies." drinking the soda causes immediate and profuse vomiting, which then spreads the disease. even plants can contract it. electrogonnorhea futurama an std humans can contract from robots. called the "noisy killer". electric flu pokémon a condition when an electric pokémon builds up too much electricity in its body or makes contact with an electromagnetic field. characterized by sparks coming from the pokémon's cheeks, a red face, and uncontrolled bursts of electricity. curable by having the pokémon expunge the excess electricity. entitilitus mr. show no one knows where entitilitus comes from, or what entitilitus is, but entitilitus kills. epideme red dwarf an intelligent virus, it was originally devised as a cure for nicotine addiction, but in practice it rapidly consumes the host before hijacking the body, and then attempting to transfer itself to another suitable host via bites or saliva transmission. if no hosts are available, epideme can force its host into a state of hibernation, encasing the body in a tomb of ice-like material until it detects life nearby and thaws. epideme steals the knowledge from every host it consumes, which has crafted it into an extremely smart, eccentric and deadly virus. european flu survivors (2008 tv series) a strain of flu based on the real spanish flu, but has killed 99.9% of mankind. fluvus pestilentia grimm (quill) an enterobacteria affecting only wesen, characterised by lack of inhibitions, strong affection, yellow boils, and, finally, psychosis. fried chicken flu (kfc virus) the fried chicken flu (boondocks) actually salmonella, but initially believed to be something far worse, causing the collapse of several governments before the real cause is revealed. genie flu genie in the house a disease of genies which causes them to change colours, become invisible and have squeaky voices. geodermic granititis look around you a disease that attacks the central nervous system, fooling it into calcifying the bodily tissue, eventually turning the victim into a pile of rocks. more commonly known as cobbles. cyberbrain sclerosis ghost in the shell: stand alone complex a disease characterized by a hardening of the brain tissues precipitated by the cyberization process. it is described as being that century's cancer or tuberculosis. cyberbrain sclerosis is described as being extremely rare, enough so that it doesn't deter most people from being cyberized, but it is incurable once diagnosed. ghost sickness supernatural a sickness which is contracted from prolonged proximity with ghosts, which causes hallucinations, fever, chills and extreme fear. dean winchester contracted this disease from an evil ghost he encountered and became immensely afraid of every single thing he encountered, even being afraid of a cat. the vanquishing of the ghost defeated the disease. groat's disease curb your enthusiasm a neurological disorder presumed to have a high mortality rate through a slow, painful process. rob reiner describes it affecting "kids and adults who have a tough time controlling their hyperactivity. it is as if you were on five cups of coffee at all times." it was named after the doctor who discovered it. larry david, who writes the show, came up with the name of the disease when he thought baseball player dick groat's name sounded like the name of a disease and in the show larry assumes it was named for dick groat, who he assumes must have had the disease because, as larry says, "he didn't field very well because he was excited all the time." hades covert one: the hades factor a blood-borne/airborne virus that causes severe internal hemorrhaging and bleeding from every orifice. it has an incubation period of 12–24 hours. kills within another 24 hours. hate plague transformers bacterial spore of unknown origin transmitted by touch. induces extreme paranoia and aggression in the infected, causing them to strike out against anyone or anything in an increasingly maddening desire to destroy. symptoms include a deep reddish glow emanating from the infected. the only curative is intense logic and wisdom, which presumably counters the extreme irrationality the disease causes in its victims. first appearing during the autobot-decepticon wars (which necessitated the second resurrection of optimus prime), a relatively milder strain is seen again during the events of beast machines; megatron triggers a pre-planted virus in silverbolt, infecting him and the rest of the maximals. the strain is cured, again, by intense logic and wisdom. harvester virus star trek: deep space nine: "armageddon game" described as a "nanobiogenic weapon", the harvesters were developed by the t'lani and kellerun from a small synthetic virus that was, itself, very lethal; the deadly and much feared weapon used during their centuries-long war killed by disrupting the victim's genetic structure, and had completely devastated the entire population of t'lani iii. so feared was this virus, that even after peace was made and the harvesters were disposed of in a ten-year project, the two governments secretly made plans to assassinate the scientists who worked on the project, fearing what might happen if they were ever remade. heart virus dragon ball z is a virus that affects one's heart, goku acquired this virus from an unknown location and had to be bedridden for days. in an alternate timeline goku dies from this virus leaving the rest of earth's special forces to be killed by androids 17 and 18, who were activated six months after goku's death. bulma creates a cure for this virus so that trunks can take it back in time to save goku and stop the androids. head-go-boom-boom-itis spongebob squarepants (squid baby) a mental disorder that causes adults that receive a head injury to develop a brain tumor that causes them to exhibit infantile-behavior, while still possessing the physical traits of an adult. head pigeons invader zim (dark harvest) a disease that involves a pigeon nesting on one's head. ms. bitters also implied the disease was contagious, ordering zim to leave before it spread to the other skoolchildren, although this seems unlikely. the treatment entails visiting a nurse, or other trained medical professional. eventually, the pigeon flies away, and the victim is deemed cured. hepatitis v true blood a virulent strain of hepatitis designed as a biological anti-vampire weapon. instead of killing them, it causes them to enter a zombie-like state: they lose all sense and become feral and aggressive, feeding and killing constantly. hinamizawa syndrome when they cry/when the cicadas cry/higurashi no naku koro ni a mental disease similar to schizophrenia. it is often referred to as "the curse of oyashiro sama" by the townspeople who have no knowledge of the disease and instead relate it to a supposed curse on the town by its guardian god, oyashiro sama.through history the villagers imposed rules to prevent the populous from becoming "demons" or in reality, stopping the symptoms from progressing. it causes paranoia-inducing hallucinations which progressively grow more threatening as the victim becomes more paranoid. in the case of the character keiichi maebara, it caused his friends' humored laughter to seem maniacal, and their tone of voice more threatening and sinister than it was. eventually, he hallucinated a marker held by mion sonozaki to be a syringe, having heard that a murderer in the town was on drugs. this caused him to kill mion, as well as rena ryuuguu, with a baseball bat. in most cases, the result of the disease involves suicide, which keiichi did by clawing his throat out. rena also once attempted suicide from the syndrome by cutting her wrist with a knife. it is revealed later in the series that hanyuu, the incarnation of oyashiro,