whey products, and other foods and supplements that contain high levels of choline. choline is an essential nutrient so complete elimination of choline is unadvised. as above, white meat (chicken, turkey) and plant based products may be fine to consume if red meat is predominantly avoided. note, while raw ingredients like soybeans have a relatively high choline content, some processed products like soy sauce, soy milk and tofu have low choline content, due to dilution of ingredients, small serving size, or removal as a byproduct during the manufacturing process. it's best to check the choline content of food and the portion size for a better understanding of how much choline is being consumed. vitamin b2 at 50 mg per day in combination with diet resolved smell issues for 2 children with tmau. b2 was found to increase residual fmo3 performance. taking low doses of antibiotics such as neomycin and metronidazole in order to reduce the amount of bacteria in the gut, although this is not recommended as a long term solution due to antibiotic resistance and other side effects. using slightly acidic detergent and body washes with a ph between 5.5 and 6.5 additionally, at least one study has suggested that daily intake of the supplements activated charcoal and copper chlorophyllin may temporarily improve the quality of life of individuals afflicted with tmau by helping their bodies to oxidize and convert tma to the odorless n-oxide (tmao) metabolite. study participants experienced subjective reduction in odor as well as objective reduction in tma and increase in tmao concentration measured in their urine. the study found that: 85% of test participants experienced complete loss of detectable "fishy" odor 10% experienced some reduction in detectable odor 5% did not experience any detectable odor reduction history the first clinical case of tmau was described in 1970. her mother related that her child, a 6 year old girl, had intermittently had a peculiar "fishy" odour. analysis of her urine showed an elevated level of trimethylamine, and that a chemially pure free base sample of trimethylamine smelled similar to the patient's fishy odor. they tested her condition by giving her more trimethylamine, which substantially increased her odour (which it did not in control subjects). notable media in 2014, singer/songwriter cassie graves was first featured in the daily mail, the daily mirror, and the metro uk newspapers in both print and online, giving an interview about her experiences with trimethylaminuria. the article was later repurposed in media across the globe, most notably by huffpost. in 2016, graves was then featured in princess productions' medical mysteries on uk's channel 5, which went on a journey to find an official diagnosis for the condition, and again sparked a global media interest in the condition. the 2010 novel boxer, beetle by ned beauman features a character with trimethylaminuria.