heart-hand syndrome, spanish type heart-hand syndrome, spanish type heart-hand syndrome, spanish type, also known as heart-hand syndrome type 3 or iii, is a very rare genetic disorder which is characterized by heart, hand, and sometimes feet abnormalities. it is a type of heart-hand syndrome, a class of genetic disorders characterized by cardiac malformations and hand malformations. only one family with the disorder has been reported in medical literature. heart-hand syndrome, spanish typeother namesheart hand syndrome type 3 (or iii), brachydactyly and intraventricular conduction defect, upper limb malformations and congenital cardiac anomalies.specialtymedical geneticssymptomsheart and hand anomaliesusual onsetconceptiondurationlife-longtypesthis is a type of heart hand syndrome, and doesn't have any subtypes itself.causesautosomal dominant inheritancediagnostic methodphysical examination, radiographypreventionnoneprognosisokfrequencyvery rare, only 1 family has ever been recorded in medical literaturedeaths- description people with this disorder have symptoms that affect the heart, hands and feet. these include: heart sick sinus bundle branch block hands brachydactyly which resembles brachydactyly type c abnormal development of the middle phalanges of the fingers accessory ossicle on the proximal phalange of the index finger. feet subtle feet anomalies such as syndactyly etimology this condition was first discovered by ruiz de la fuente et al., when they described a 3-generation family from spain with the symptoms mentioned above. the cardiac defects varied between family members; 3 members had intraventicular conduction defects and 1 had a sick sinus. in this family, the 2nd and 5th fingers were the most severely affected out of all the fingers. autosomal dominant inheritance was suspected.