clomegestone acetate clomegestone acetate clomegestone acetate (usan) (developmental code name sh-741), or clomagestone acetate, also known as 6-chloro-17α-acetoxy-16α-methylpregna-4,6-diene-3,20-dione, is a steroidal progestin of the 17α-hydroxyprogesterone group which was developed as an oral contraceptive but was never marketed. it is the acetate ester of clomegestone, which, similarly to clomegestone acetate, was never marketed. clomegestone acetate is also the 17-desoxy cogener of clometherone, and is somewhat more potent in comparison. similarly to cyproterone acetate, clomegestone acetate has been found to alter insulin receptor concentrations in adipose tissue, and this may indicate the presence of glucocorticoid activity. clomegestone acetateclinical dataother namesclomagestone acetate; sh-741; 6-chloro-17α-acetoxy-16α-methylpregna-4,6-diene-3,20-dionedrug classprogestogen; progestogen esteridentifiers iupac name (1s,2r,10r,11s,13r,14r,15s)-14-acetyl-8-chloro-2,13,15-trimethyl-5-oxotetracycloheptadeca-6,8-dien-14-yl acetate cas number424-89-5pubchem cid20055456chemspider16736896unii8oij6341w7keggd03550chemblchembl2104126comptox dashboard (epa)dtxsid40962456 chemical and physical dataformulac24h31clo4molar mass418.96 g·mol−13d model (jsmol)interactive image smiles cc1cc2c3c=c(c4=cc(=o)ccc4(c3ccc2(c1(c(=o)c)oc(=o)c)c)c)cl inchi inchi=1s/c24h31clo4/c1-13-10-19-17-12-21(25)20-11-16(28)6-8-22(20,4)18(17)7-9-23(19,5)24(13,14(2)26)29-15(3)27/h11-13,17-19h,6-10h2,1-5h3/t13-,17-,18+,19+,22-,23+,24+/m1/s1key:wwskhpdyswdmnc-yrnsvobjsa-n