list of adverse effects of lurasidone list of adverse effects of lurasidone this is a list of adverse effects of the antipsychotic drug lurasidone, sorted by frequency of occurrence. very common very common (>10% incidence) adverse effects include: somnolence (dose-dependent; produces an intermediate degree of sedation compared to other atypical antipsychotics) akathisia (dose-dependent) fasting glucose increased nausea parkinsonism common common (1–10% incidence) adverse effects include: vomiting dyspepsia agitation anxiety dystonia dizziness fatigue back pain restlessness hypersalivation weight gain uncommon uncommon (0.1–1% incidence) adverse effects include: orthostatic hypotension syncope stroke seizure suicidal ideation elevated serum creatinine rare rare (0.01–0.1% incidence) adverse effects include: agranulocytosis leukopaenia neutropaenia tardive dyskinesia neuroleptic malignant syndrome unknown frequency unknown frequency adverse effects include: transient ischaemic attack hyperprolactinaemia (seems to be a rather prominent adverse effect according to a meta-analysis) hypothermia