2,α-dimethyltryptamine 2,α-dimethyltryptamine 2,α-dimethyltryptamine (2,α-dmt) is a tryptamine and a lesser-known psychedelic drug. it is the 2,α-dimethyl analog of dmt. its synthesis was first reported in 1965. alexander shulgin lists the dosage as 300-500 mg, and the duration as 7–10 hours in his book tihkal (tryptamines i have known and loved). 2,α-dmt causes mydriasis and paresthesia. it also produces a calm, drunk-like feeling. very little data exists about the pharmacological properties, metabolism, and toxicity of 2,α-dmt. 2,α-dimethyltryptamineidentifiers iupac name 1-(2-methyl-1h-indol-3-yl)propan-2-amine cas number4966-28-3chemspider23511903 ychemical and physical dataformulac12h16n2molar mass188.274 g·mol−13d model (jsmol)interactive image smiles cc1c(c2ccccc21)cc(c)n inchi inchi=1s/c12h16n2/c1-8(13)7-11-9(2)14-12-6-4-3-5-10(11)12/h3-6,8,14h,7,13h2,1-2h3 ykey:axzqfxrpuljfqk-uhfffaoysa-n y (verify)