apronal apronal apronal (brand name sedormid), or apronalide, also known as allylisopropylacetylurea or allylisopropylacetylcarbamide, is a hypnotic/sedative drug of the ureide (acylurea) group synthesized in 1926 by hoffmann-la roche that is no longer used except in japan (see japanese article). though it is not a barbiturate, apronalide is similar in structure to the barbiturates (being an open-chain carbamide instead of having a heterocyclic ring). in accordance, it is similar in action to the barbiturates, although considerably milder in comparison (formerly used as a daytime sedative at doses of 1 to 2 grams every 3 to 4 hours). upon the finding that it caused patients to develop thrombocytopenic purpura, apronalide was withdrawn from clinical use. apronalclinical dataroutes ofadministrationoralatc coden05cm12 (who) pharmacokinetic dataexcretionrenalidentifiers iupac name (±)-n-carbamoyl-2-propan-2-ylpent-4-enamide cas number528-92-7 ypubchem cid10715chemspider10264 yuniiv18j24e25ekeggd03975 ychemblchembl509282 ycomptox dashboard (epa)dtxsid00862125 echa infocard100.007.677 chemical and physical dataformulac9h16n2o2molar mass184.239 g·mol−13d model (jsmol)interactive imagechiralityracemic mixture smiles o=c(nc(=o)n)c(c(c)c)c\c=c inchi inchi=1s/c9h16n2o2/c1-4-5-7(6(2)3)8(12)11-9(10)13/h4,6-7h,1,5h2,2-3h3,(h3,10,11,12,13) ykey:ksuumawcgdnlfk-uhfffaoysa-n y (verify)