very cost-efficient relative to alternate therapies. total charges to maintain pn at home can reach upwards of $150,000 a year, even though the actual cost of nutrition is typically only $18 to $22 a day. this excludes the cost for additional home support, equipment, and the care of pn-related complications. the cost involved in undergoing intestinal transplantation, including the initial hospitalization for the transplant, can range from $150,000 to $400,000, and reoccurring hospitalizations are common up through the second year. two to three years post-transplant, the financial cost of transplantation reaches parity with pn and is more cost-effective thereafter.