female genital disease female genital disease a female genital disease is a condition that affects the female reproductive system. female genital diseasespecialtygynaecology background pathological mechanisms in the female reproductive system. classification by type of disease malformation malformations can be congenital. they are classified by location of the malformation, such as uterine malformation. inflammation and/or infection an example is oophoritis. classification by location alternatively, female genital diseases can be more strictly classified by location of the disease, which, in turn, can be broadly divided between diseases that affect the female internal genitalia and those that affect the female external genitalia.