16-methylene-17α-hydroxyprogesterone acetate 16-methylene-17α-hydroxyprogesterone acetate 16-methylene-17α-hydroxyprogesterone acetate is a progestin of the 17α-hydroxyprogesterone group which was never marketed. given orally, it shows about 2.5-fold the progestogenic activity of parenteral progesterone in animal bioassays. it is a parent compound of the following clinically used progestins: chlormethenmadinone acetate (6-chloro-16-methylene-17α-hydroxy-δ6-progesterone acetate) melengestrol acetate (6-methyl-16-methylene-17α-hydroxy-δ6-progesterone acetate) methenmadinone acetate (16-methylene-17α-hydroxy-δ6-progesterone acetate) segesterone acetate (16-methylene-17α-hydroxy-19-norprogesterone acetate) 16-methylene-17α-hydroxyprogesterone acetateclinical dataother names16-methylene-17α-acetoxyprogesterone; 16-methylene-17α-acetoxypregn-4-en-3,20-dionedrug classprogestogen; progestin; progestogen esteridentifiers iupac name phenanthren-17-yl] acetate cas number6815-51-6pubchem cid151431chemspider133463uniixyo20awr0icomptox dashboard (epa)dtxsid20987647 chemical and physical dataformulac24h32o4molar mass384.516 g·mol−13d model (jsmol)interactive image smiles cc(=o)1(c(=c)c21(cc32ccc4=cc(=o)cc34c)c)oc(=o)c inchi inchi=1s/c24h32o4/c1-14-12-21-19-7-6-17-13-18(27)8-10-22(17,4)20(19)9-11-23(21,5)24(14,15(2)25)28-16(3)26/h13,19-21h,1,6-12h2,2-5h3/t19-,20+,21+,22+,23+,24+/m1/s1key:xsnmcqgnvpsiqm-ckozhmepsa-n