anterior hypothalamic nucleus anterior hypothalamic nucleus the anterior hypothalamic nucleus is a nucleus of the hypothalamus. anterior hypothalamic nucleusanterior hypothalamic nucleus is 'ah', at center left, in blue.detailsidentifierslatinnucleus anterior hypothalamimeshd007025neuronames386neurolex idbirnlex_1226ta98a14.1.08.903ta25719fma62319anatomical terms of neuroanatomy its function is thermoregulation (cooling) of the body. damage or destruction of this nucleus causes hyperthermia. the anterior hypothalamus plays a role in regulating sleep. the anterior hypothalamic region is sometimes grouped with the preoptic area.