acotiamide acotiamide acotiamide, sold under the brand name acofide, is a medication manufactured and approved in japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. it acts as an acetylcholinesterase inhibitor. acotiamideclinical datatrade namesacofideother namesym-443, z-338routes ofadministrationby mouthatc codea03fa10 (who) legal statuslegal status jp: rx-only pharmacokinetic dataprotein binding84.21–85.95%metabolismugt1a8 and 1a9 (major)elimination half-life10.9–21.7 hoursexcretionfeces (92.7%), urine (5.3%)identifiers iupac name n--2--1,3-thiazole-4-carboxamide cas number185106-16-5 npubchem cid5282338chemspider4445505 yuniid42owk5383keggd08838 nchemblchembl2107723 nchemical and physical dataformulac21h30n4o5smolar mass450.55 g·mol−13d model (jsmol)interactive image smiles o=c(nc1nc(c(=o)nccn(c(c)c)c(c)c)cs1)c2cc(oc)c(oc)cc2o inchi inchi=1s/c21h30n4o5s/c1-12(2)25(13(3)4)8-7-22-20(28)15-11-31-21(23-15)24-19(27)14-9-17(29-5)18(30-6)10-16(14)26/h9-13,26h,7-8h2,1-6h3,(h,22,28)(h,23,24,27) ykey:twhznaubxfzmca-uhfffaoysa-n y ny (what is this?) (verify)