is another drug that may cause hypersomnolence and microsleeps. most microsleeps are not clinically significant, however. individuals who feel sleepy and wish to maintain alertness often consume over-the-counter stimulants such as caffeine in coffee. more specifically, it has been shown that high-frequency low-dose caffeine intake is effective at countering poor work performance effects due to extended wakefulness, confirming the hypothesis that adenosine is a mediator of performance decrements associated with extended wakefulness. other stimulants that could decrease microsleep frequency include adderall, amphetamine, cocaine, and tobacco.