am-855 am-855 am-855 (part of the am cannabinoid series) is an analgesic drug which is a cannabinoid agonist. it is a derivative of δ8tetrahydrocannabinol with a conformationally restricted side chain which has been bound into a fourth ring fused to the aromatic a-ring of the cannabinoid skeleton. am-855 is an agonist at both cb1 and cb2 with moderate selectivity for cb1, with a ki of 22.3 nm at cb1 and 58.6 nm at cb2. am-855identifiers iupac name (4ar,12br)-8-hexyl-2,5,5-trimethyl-1,4,4a,8,9,10,11,12b-octahydronaphthoisochromen-12-ol cas number249888-50-4 ypubchem cid10091328chemspider8266865 yuniija784tpz1uchemblchembl303479 ychemical and physical dataformulac26h38o2molar mass382.588 g·mol−13d model (jsmol)interactive image smiles oc1c4c2cc(c)=ccc2c(c)(c)oc4cc3c1cccc3cccccc inchi inchi=1s/c26h38o2/c1-5-6-7-8-10-18-11-9-12-19-20(18)16-23-24(25(19)27)21-15-17(2)13-14-22(21)26(3,4)28-23/h13,16,18,21-22,27h,5-12,14-15h2,1-4h3/t18?,21-,22-/m1/s1 ykey:gaajnvwioiompo-ipkcrjezsa-n y (verify)