subserosa subserosa the subserosa or tela subserosa, is a thin layer of tissue in the walls of various organs. it is a layer of connective tissue (usually of the areolar type) between the muscular layer (muscularis externa) and the serosa (serous membrane). subserosalayers of stomach wall: serosamuscularisoblique fibers of muscle wallcircular muscle layerlongitudinal muscle layersubmucosalamina muscularis mucosaemucosalamina propriaepitheliumgastric glandsgastric pitsvillous foldsgastric areas (gastric surface)identifiersta98a12.1.08.009 a05.4.01.008 a05.5.01.020 a05.6.01.003 a05.7.01.003 a05.8.01.053 a05.8.02.007 a07.1.02.004 a07.1.02.011 a08.3.01.009 a09.1.02.011 a09.1.03.024 a09.3.01.015 a10.1.02.004ta22900, 2908, 2935, 2965, 3057, 3324, 3344, 3408, 3496, 3519, 3586, 3731, 3949fma45636anatomical terminology the subserosa has clinical importance particularly in cancer staging (for example, in staging stomach cancer or uterine cancer). the subserosa (sub- + serosa) is to a serous membrane what the submucosa (sub- + mucosa) is to a mucous membrane.