of rosalia rosselini by cumberland college professor albert sartre. sartre and his son attempted to use the virus to cure all disease, but instead found that it could not be used for positive means. an outbreak of the virus occurred, resulting in the cumberland college incident, where sartre and rosalia escaped to mexico, and his son lost all memory of the incident, but was arrested and sentenced to 250 years of imprisonment under the id "cr-s01". however, sartre was inflicted with the virus, causing him to fall to insanity, killing rosalia. rosalia's blood splattered onto nearby flowers, which monarch butterflies fed upon, acting as vectors that caused a second outbreak. a variation of the rosalia virus was encountered once, when one of the rosalia patients, naomi kimishima, also had a pre-existing incurable genetic disease (thought to be related to guilt). interactions between the genetic disease and rosalia gave birth to a "twisted rosalia" strain, which only one case was known to be documented. scorched plague fallout 76 a plague caused by scorchbeasts, giant bat-like mutants created by the enclave in 2083. symptoms can include a loss of higher brain function, growths of ultracite protruding from the affected's skin, and a connection to the scorchbeast hive mind. people with the plague go through a skin transformation that goes from a charred, blackened appearance to red lesions and the appearance of being flayed alive. scorched also develop cataracts in the eyes and experience complete hair loss. the plague wipes out most of the residents of west virginia, save for the player characters/vault 76 inhabitants. additionally, all scorched victims have a set lifespan, at the end of which they stay in a single position until their bodies petrify from the inside out. they retain enough mental faculties to operate smaller firearms and various melee weapons, as well as wear armor for protection. the scorched are hostile toward anything that they perceive as a threat. scp-610 scp foundation a highly infectious skin disease which was first reported by the russian government in the 1970s. the disease begins as a normal skin disease which irritates the infected, causing itching and bad skin. but then searing temperatures increase the infection and spread it through the body, causing skin to rot and mutate. eventually the affected is covered from head to toe in infectious sores. the affected individual is then declared clinically dead and reanimates after a while, and will attempt to infect anyone else they encounter. the foundation has been trying to contain this disease, but they may be unsuccessful because of its fast contagion spread. skull shivers borderlands stigma trauma center: new blood a virus accidentally created by markus vaughn and lloyd wilkens. it is later used as a bioterror weapon by the group parnassus. it comes in six strains, named after body parts it resembles or attacks (cheir, soma, ops, onyx, brachion, cardia). unlike other pathogens, which store their genetic information in dna, stigma stores its genetic information in a film-like structure making it unique among pathogens. due to the fact that stigma originated from a lab rat with culurium-based synthetic blood, a newly discovered mineral from the country of culuruma, taking control of the mines that contain the mineral is necessary for the mass production of stigma. syphon filter syphon filter series a bio-weapon that can be genetically programmable to terminate specific genotypes, killing only intended victims while leaving non-targeted parties alive. because it binds with each host's specific dna, it does not possess a universal vaccine, and in order to cure it, one must know the specific genetic lock and key for each strain of the disease. t-abyss virus resident evil series a variant of the t-virus, designed by fbc ceo morgan lansdale to show the world the dangers of bio-weapons and increase his own personal power through use of the 'veltro' terrorist group. the virus crates zombies and bows who are strongly linked with water, and have numerous aquatic features such as tentacles and crab-like shells. it is encountered in the game when 'veltro' threaten to infect the world's oceans, hoping to exact revenge for the loss of much of their forces during the bio-terrorist attack on the floating techno-utopia terragrigia. it is encountered during exploration of three research vessels, where it has transformed the crew and several sea creatures into zombies, mutants and tyrants. t-phobos virus resident evil series a variant of the t-virus originating back in the 1960s as part of the wesker project. as named after the god of terror phobos, the tyrant phobos virus creates zombies and bows which are triggered through their host's reactions in their mind. if the host experienced enough fear, the virus will mutate quickly. t-veronica virus resident evil series a powerful strain of the progenitor virus, created by combining it with a rare retrovirus found in the genetic make-up of ant queens, discovered by unstable scientific genius alexia ashford, the result of an advanced cloning experiment. it is encountered in resident evil – code: veronica, when it is being used by alexia ashford in her attempt to take control of the world. she experiments on her father, then on herself; her father is transformed into a terrifying monster, while she, going into hibernation after giving herself a dose of the virus, manages to gain control over it and retain her personality and intelligence. she eventually becomes a dragonfly-like creature who has to be killed by chris redfield. it appears again in the 'operation javier' section of darkside chronicles, where it is being used by javier hidalgo to cure his daughter manuela of an inherited illness. he also tried to cure his wife, but the virus overwhelmed her and turned her into a mutant. manuela uses her developing powers (similar to alexia ashford's abilities before transforming into her insect form) to defeat the mutated javier, and is then evacuated by leon kennedy and jack krauser. if manuela survives at the end of the game, it is said that she is cared for by the us government, but her ultimate fate is left unknown. t-virus (tyrant virus) resident evil series a highly contagious virus, spread mostly through liquids such as bodily fluids and water, that causes cellular necrosis in humans and other animals, turning them into zombie-like creatures who are difficult to kill. it can easily mutate into other strains, some of which have mutagenic effects on the host. in insects or amphibians, the resulting mutation often involves increased aggressiveness, increased size, and (almost always) the development of poisonous traits. in mammals, the results include aggressiveness, physiological changes of varying degrees, and an extremely increased evolutionary rate. however, it is shown that some humans can bond with the t-virus and its variants and gain heightened speed, strength and strange powers while retaining their personalities, as in the case of albert wesker and alexia ashford. variants include the ne-t virus, along with many others. technocyte virus (the infestation) warframe the technocyte virus mutates both flesh and metal alike. it disfigures and dismembers anybody it infects, turning them into a raging and mindless creature. these infected entities and the virus itself make up a faction known as the "infestation." notable infested entities include lephantis, jordas golem, and phorid. the virus itself can take over something as insignificant as a simple drone to an entire corpus obelisk. tiberium poisoning command & conquer tiberium crystals start to grow on a person's skin. these skin crystals eventually force their way through the persons vital organs, killing them. if the infestation is in a certain proportion, the affected mutates into a living bag of rotten skin and organs, called a visceroid. turbo cancer borderlands unicornitis octodad: dadliest catch a disease made up during a story told by tommy and stacy in the bonus episode "medical mess". symptoms include a bright pink unicorn horn magically sprouting from the forehead, and the ability to fly. the only known cure is to purchase and use a set of jet-skis. notable affected individuals include patient 203 and octodad. uroboros resident evil series an advanced strain of the progenitor virus, the uroboros virus was created by albert wesker, with inadvertent help from jill valentine. exposure to uroboros can lead to one of two things—forced evolution via dna integration, leading to extremely heightened abilities, or rejection via the virus, leading to the parasitic nature taking over and forming a mass of black, leech-like pustules, which can grow in size if exposed to more organic matters. the only individual known to survive the process was albert wesker, which was more than likely due to the fact of his previous exposure to the t-virus. other beings that took positive mutations from the uroboros virus include the reapers; cockroaches exposed accidentally to the virus, who then in turn grew largely in size, gained armour-like carapaces and scythe-like appendages, explaining the name. wailing death neverwinter nights a bubonic-like plague that infects almost the entire city of neverwinter. thought to be just a natural plague, it is later discovered that it was magically created and unleashed upon the city. x-2 virus battletanx, battletanx: global assault an extremely deadly virus released in 2001 and further researched in 2006 that killed 99.9% of the world's human female population that did not possess a special psychic ability known as 'the edge'. those that were spared were treated with the utmost respect, authority, and loyalty, thereby earning their title of 'queenlord'. yellow death 1213 a deadly virus which contaminated the entire planet earth and certain parts of the tessa life orbital. humans are killed in short time upon infection, but cloned humans are transformed into killer zombies. when 0916 got a large dosage of the virus he mutated into a yellow, four-armed monster with two retractable spines and tentacles. 1213 however was unaffected by the virus due to a successful immunization to the virus. twin fever metroid prime a virus native to twin tabula causing double vision. when the twin sight fades, the affected is near death. kuru dead island, dead island riptide, dead island 2 is a sub-type version of kuru which later actually revealing is neuro-genetically engineered version of kuru that infected islands to the papua new guinea region. it is widely passed among the local tribes and is believed to be the cause of the zombie outbreak. doctor west needs a non-mutated strain of this disease to work on a cure. doctor west also believes that people with o negative blood are unsusceptible to the infection tuurngait virus penumbra: black plague the tuurngait virus is a disease that can affect humans and animals, it was later discovered by the archaic led by philip's father howard lafresque and his crew members in greenland. it was later tested and found out that one of its effects is mutation. in role playing games name source symptoms amalgamation undertale applicable to monsters who have "fallen down," the specific wording for those who have recently died. monsters turn to dust shortly after death, unless if injected with determination prior to this. in that case, the moster will awaken within a short period before becoming a gloopy, melted form of what they once were. these forms are titled amalgamates. their abilities (such as attacks, speech patterns, behavior) become corrupt and sluggish. if multiple amalgamates are in the vicinity of one another, they will merge and become an unusual new being with combined traits of the originals. amalgamates are often hostile and will try to harm the player, but contrastingly cannot be killed, harmed, or reverted back into their original forms. though not technically a disease, it is an uncureable eternal zombification. goblin fever dungeon adventures #46, "goblin fever" this disease is a relatively harmless ailment to goblins, orcs, and similar creatures, but it is rare. to humans, it is much deadlier. having a long incubation period and being highly contagious, an outbreak can start before the first case is even detected. the disease causes deterioration of the central nervous system, causing forgetfulness and rapid mood swings, the affected often becoming violent, depressed, or even suicidal, eventually lapsing into a coma before dying. free league plague planescape a plague created by the lady of pain to keep the swelling numbers of the free league in check, which grew to an overwhelming size after a conflict called the