to enhance infectivity, severity and lethality. certain abilities also include drug resistance, to avoid being eliminated by ai-controlled cure research while wiping out humanity. the affliction guild wars also referred to as 'the canthan plague'. a disease that spread in cantha, causing those affected to become hulking, aggressive, pained creatures known as 'the afflicted'. it was seen to affect humans, cattle, and various animals in a menagerie. the affected were initially believed to be contagious, but this was later found out to be false. ancient virus resident evil series a rare viral strain found in queen ant genes. it was discovered by alexia ashford, while she was studying ants. when combined with the progenitor virus, it creates the powerful t-veronica virus. probably the control power of it is due to the ancient virus. angel toxicosis tales of symphonia the name given by raine sage to symptoms of cruxis crystal parasitism. causes victim to eventually lose ability to taste, sleep, cry, feel pain, and talk. also increases the victim's hearing, strength and sight abilities, as well as eliminating the need to eat and sleep. in early beginnings it allows the victim to gain crystal-like wings and fly until the disease is destroyed. the final stage of this diseases causes the victim to give up their heart and memory, and ultimately their life. the disease lasts for an unknown time, those affected are slowly "given" the symptoms via blessings of a person with a mounted cruxis crystal. a major example is collette, one of the eight protagonists of the game. atma virus digital devil saga a mystical, noncommunicable virus which marks its carriers with a tattoo-like mark somewhere on their bodies. carriers who are immune to cuvier syndrome can transform into a demonic reflection of their inner personalities, referred to as atma. however, everyone with the virus feels an insatiable hunger for the flesh of other carriers. if this hunger is resisted for too long, the carrier will eventually enter an irreversible state of mindless bloodlust, losing the ability to return to human form. asmodeus terranigma many ages before ark's adventure to the surface of the world, the previous generations of humanity were decimated by an airborne virus with an estimated mortality rate of 90%. the virus was named by dr. beruga who was able to synthesize a vaccine of 80% effectiveness for it. asmodeus was later utilized as a bio-weapon to completely depopulate a city, save for one child survivor who was seemingly unaffected and hid underground. blacklight virus prototype the blacklight virus "plugs in" and activates the junk dna in a target, causing biological changes that create (and recreate) a sentient mind inside the infected creature. it acts by affecting the protein encoding regions of the promoter introns in each cell. as a retrovirus, it contains both rna and the reverse transcriptase enzyme, allowing it to insert its own genetic codes into living cells. it enters, re-purposes and changes the cell, replicating previously dormant non-coding segments of dna. more often than not, these changes are too drastic and 99.99% of subjects die from massive organ failure and cell saturation. however some variants have yielded other beneficial results; endowing the infected organisms with incredible superhuman genetic prowess, that greatly increase their natural abilities to levels far exceeding human capability. blight dragon age the blight disease is a kind of corruption spread by the evil darkspawn. the disease corrupts all living organisms which either go mad, develop physical afflictions, and/or perish outright.the longer an infected creature 'lives', the more it will manifest hair loss, aggressive or even rabid behavior and numerous deformities, protrusions, boils and sores. cariappa-muren disease neurocracy a transmissible spongiform encephalopathy spread primarily by consuming contaminated farmed atlantic bluefin tuna. the pandemic spread of cmd from 2034 to 2040 led to the widespread adoption of neural colloids, a form of implantable microelectrode array, that detect chemical signatures of cmd to allow for rapid diagnosis and containment. chimeran virus resistance: fall of man a virus introduced to earth by alien invaders known as the chimera. the chimeran virus mutates the dna of infected humans, transforming them into various entities composed of a mixture of human, chimeran, and animal dna, in order to create an army of modified soldiers to fight for their cause. chronic angelus crystallus inofficium tales of symphonia a progressive disease caused by a cruxis crystal mounted upon a key crest. the wearer's body gradually crystallizes, starting with the skin, into the same substance that forms exspheres. when the crystallization reaches the internal organs, the affected individual perishes. chrono-displasia league of legends a mystical disease that grants immortality but detaches the affected's consciousness from the present time, making their mind drift through time, from any point they have already lived to the present, unable to impact the events which unfold. corprus the elder scrolls iii: morrowind corprus causes incredible mutations in humanoids, but it is an almost non-communicable disease. people infected with blight are often sent to a special institution called the corprusarium, which was made for researching corprus. corprus is caused by the volcanic ash that emanates from red mountain, but, as a positive side effect, grants 100% disease immunity. the only known antidote is proven to destroy corprus, but ends up killing the victim as well. however, the player is able to take the antidote without any adverse effects, presumably because they are the reincarnation of nerevar. cordyceps brain infection the last of us a mutated form of the cordyceps fungus known as cordyceps brain infection (abbreviated to cbi) that infects the united states in 2013, causing humans to transform into cannibalistic monsters known as the infected. the virus destroys most of civilization over the course of 20 years, leaving 60% of humanity either infected or dead, with the surviving human population either living in heavily policed quarantine zones, isolated communities or nomadic groups. the infected beings are split between four categories depending on how long they were infected for: runners - fast, irritable and hostile, caused within 1–2 days of being infected; stalkers - fast, aggressive and stealthy, caused within 1 week to 1 month of being infected; clickers - despite being blind, they use echolocation to locate enemies and are also strong, caused within 2–4 years of being infected; and bloaters - also blind and use echolocation, they are also armored, powerful and extremely aggressive, caused within 10 years of being infected. corrupted blood world of warcraft initially contracted from fighting hakkar, the god of blood, in the dungeon of zul'gurub. highly infectious, with an incubation period of two seconds and can infect any person in the immediate area. referred to players as "the plague", "hakkar's sars" or "wow aids" for a major outbreak of the virtual plague in the game due to a design oversight. creeping derangea advance wars: days of ruin an artificial virus that is revealed to be a failed bio-weapon created by dr. caulder to test the extent of ids technology. due to its inherent flaw of photophobia, creeping derangea is only able to thrive when the sun was effectively blocked out by the vast amounts of dust that were kicked up into the troposphere and stratosphere by the apocalyptic meteor impact events. the virus is initially only able to infect those under the age of 20 but a new strain is somehow introduced that can infect older hosts over time. symptoms include headaches, paranoia, and a black diamond on the skin called "the mark". it causes flowers to grow inside a person and break out of the skin. a beautiful, albeit excruciatingly painful, way to die. its scientific name is endoflorescens terribilis. it is also known as the creeper and the green thumb. c-virus resident evil series a further evolved version of the t-virus. developed by neo-umbrella, it is responsible for creating the highly evolved, more intelligent j'avo, as well as being used in the worldwide bio-terrorist attacks. jake muller, being descended from albert wesker, is resistant to the disease. because of this, jake is seemingly being hunted by ada wong and her agents. cuvier syndrome digital devil saga 2 caused by exposure to corrupted sunlight, this noncommunicable disease petrifies the bodies of its victims, literally turning them to stone. the rate of petrification seems to be based on the level of sunlight exposure: one victim in full sunlight attempted suicide, but was unable to pull the trigger before being petrified. carriers of the atma virus are immune. desert herpes wasteland a sexually transmitted disease that the player's character contracts if he sleeps with the three-legged prostitute he meets in the game. despair disease danganronpa 2: goodbye despair a pathogen created by monokuma in order to drive the students into paranoia and irritability. its effects depend on the person it infects: nagito komaeda's symptoms caused him to impulsively lie, akane owari became a coward, ibuki mioda became emotionless and gullible, and it caused mikan tsumiki to remember the events prior to having her memory erased. the disease wore off once there was another victim in the killing game. diathronitis larn afflicts daughter of player character; serves as primary motivation for gameplay. dire aids south park: the stick of truth a form of aids that causes minor health drain when the player's turn begins. its contracted by being hit by the physical attacks of wildlife in canada. going to the hospital in canada can "cure" the player, but an unlockable achievement requires the player to defeat the final boss while infected. doll syndrome hack gu.hack//g.u. a mysterious medical condition in which a person falls into a completely unresponsive state. doll syndrome is in fact a physical side effect to an infection by aida. salvador aihara tries to do an undercover investigation regarding doll syndrome in especially young children for his show "online jack". element 115 call of duty: online, call of duty: black ops element 115 was used to create the zombies as one of its side effects was the reanimation of dead cells. the zombies were to be used as super-soldiers by the nazis. after creating them, the nazis realized that they were uncontrollable and would lead to mankind's destruction. can be combined with nova 6 to create dirty bombs. shiva i-vii fallen earth the shiva virus, or at least shiva i, is hinted to be an airborne virus with a quick infection exposure time, and therefore has qualities much like a modern chemical weapon. overall the shiva virus appears as seven distinct forms, with naming conventions of shiva i through shiva vii, with the seventh version being mostly non-lethal. the virus is named after shiva, the hindu god of death due to the dance-like convulsions that it causes its victims the filth the secret world a biological weapon willed into existence by the dreamers in their attempts to free themselves from captivity, it manifests in a variety of forms, including poisonous gas, parasitic fungi, radio waves, and even words. the most common variant takes the form of a viscous black fluid. exposure to the filth results in nightmares, respiratory difficulties, paranoia, delusions, violent behavior, and eventual insanity; mutations gradually set in, resulting in victims manifesting glowing red eyes, tentacles, and exuding filth from their skin. affected individuals ultimately fall under the influence of the dreamers and are devoted either to releasing them from their prisons or continuing the spread of the disease. further mutations may occur following this stage, and more exotic forms of the filth can result in more unusual symptoms, one rare case transforming the victim into a disembodied intelligence migrating between infected individuals. no cure exists. flood parasite halo the flood parasite is depicted in the halo franchise as a parasitoid fungus-like pathogen that mutates infected hosts into creatures similar to zombies. depending on the size or condition of the host's body, the flood will either uses the host as-is to pursue new victims, or break it down to create "pure forms" from its biomass. forced evolutionary virus fallout originally known as the pan-immunity viron project, fev, along with radiation, is responsible for many mutations in the wastelands. the most visible of these are the super mutants, former humans granted incredible strength and endurance as result of being infected. exposure to the virus is also known to be fatal in many cases. fev serves