ibogamine ibogamine ibogamine is an anti-convulsant, anti-addictive, cns stimulant alkaloid found in tabernanthe iboga and crepe jasmine (tabernaemontana divaricata). basic research related to how addiction affects the brain has used this chemical. ibogamineclinical dataatc codenoneidentifiers iupac name -7-ethyl-6,6a,7,8,9,10,12,13-octahydro-6,9-methano-5h-pyridoazepinoindole cas number481-87-8 npubchem cid100217chemspider90568 ychebichebi:5853 ycomptox dashboard (epa)dtxsid30963997 chemical and physical dataformulac19h24n2molar mass280.415 g·mol−13d model (jsmol)interactive image smiles cc1c2c31n(c2)ccc4=c3nc5=cc=cc=c45 inchi inchi=1s/c19h24n2/c1-2-13-9-12-10-16-18-15(7-8-21(11-12)19(13)16)14-5-3-4-6-17(14)20-18/h3-6,12-13,16,19-20h,2,7-11h2,1h3/t12-,13+,16+,19+/m1/s1 ykey:lrlcvrykafdxku-ygosvgotsa-n y ny (what is this?) (verify) ibogamine persistently reduced the self-administration of cocaine and morphine in rats. the same study found that ibogamine (40 mg/kg) and coronaridine (40 mg/kg) did not produce "any tremor effects in rats that differ significantly from saline control". while the related alkaloids ibogaine (20–40 mg/kg), harmaline (10–40 mg/kg) and desethylcoronaridine (10–40 mg/kg) were "obviously tremorgenic". chemistry synthesis ibogamine can be prepared from one-step demethoxycarbonylation process through coronaridine. pharmacology like ibogaine, it has seems to have similar pharmacology. it has effects on kor, nmdar, nachr and serotonin sites. it also inhibits acetylcholinesterase and butyrylcholinesterase.