isothipendyl isothipendyl isothipendyl is a 1st generation h1 antagonist (antihistamine) and anticholinergic used as an antipruritic. it is nowadays scarcely used in the 1st line relief of allergies due to the anticholinergic side effect of somnolence but does have some limited use through topical application in the relief of insect bites and related itching (pruritus). isothipendylclinical dataahfs/drugs.cominternational drug namesatc coded04aa22 (who) r06ad09 (who)identifiers iupac name n,n-dimethyl-1-(10h-pyridobenzothiazin-10-yl)propan-2-amine cas number482-15-5 1225-65-6pubchem cid3781drugbankdb08802 ychemspider3649 yuniiwvz7k9p0jykeggd08091 ycomptox dashboard (epa)dtxsid5048267 echa infocard100.006.890 chemical and physical dataformulac16h19n3smolar mass285.41 g·mol−13d model (jsmol)interactive image smiles n2c1n(c3c(sc1ccc2)cccc3)cc(n(c)c)c inchi inchi=1s/c16h19n3s/c1-12(18(2)3)11-19-13-7-4-5-8-14(13)20-15-9-6-10-17-16(15)19/h4-10,12h,11h2,1-3h3 ykey:oqjbsdffqwmkbq-uhfffaoysa-n y (verify)