urine organic acids urine organic acids urine organic acids is a medical diagnostic test that measures organic acid metabolites in the urine. the metabolites can come from host cells or from flora. the test can be used to exclude the possibility that a person has an inborn error of metabolism, usually one of the organic acidemias. it is also used to look for problems with nutrition or evidence of certain infections or bacterial overgrowth. the usual method of analysis is tandem mass spectrometry. urine organic acidspurposemeasures organic acid metabolites in urine gc-ms total ion chromatogram of a urine sample in a patient with diabetic ketoacidosis