gr-159897 gr-159897 gr-159897 is a potent and selective nk2 receptor antagonist drug. it has anxiolytic effects in animal models, and also inhibits bronchoconstriction of the airways, which may potentially make it useful in the treatment of asthma. gr-159897identifiers iupac name 5-fluoro-3-(2-(4-methoxy-4-(methyl)-1-piperidinyl)ethyl)-1h-indole cas number158848-32-9 ypubchem cid9555764chemspider2807862comptox dashboard (epa)dtxsid20393749 chemical and physical dataformulac23h27fn2o2smolar mass414.54 g·mol−13d model (jsmol)interactive image smiles c4ccccc4s(=o)cc2(oc)ccn(cc2)ccc(c1cc3f)cc1cc3 inchi inchi=1s/c23h27fn2o2s/c1-28-23(17-29(27)20-5-3-2-4-6-20)10-13-26(14-11-23)12-9-18-16-25-22-8-7-19(24)15-21(18)22/h2-8,15-16,25h,9-14,17h2,1h3key:banyjbhwtojqdu-uhfffaoysa-n (verify)