urb597 urb597 urb597 (kds-4103) is a relatively selective and irreversible inhibitor of the enzyme fatty acid amide hydrolase (faah). faah is the primary degradatory enzyme for the endocannabinoid anandamide and, as such, inhibition of faah leads to an accumulation of anandamide in the cns and periphery where it activates cannabinoid receptors. urb597 has been found to elevate anandamide levels and have activity against neuropathic pain in a mouse model. urb597 names preferred iupac name 3′-carbamoyl-3-yl cyclohexylcarbamate identifiers cas number 546141-08-6 y 3d model (jsmol) interactive image chembl chembl184238 y chemspider 1156960 y echa infocard 100.164.994 iuphar/bps 4339 mesh urb597 pubchem cid 1383884 unii px47lb88fo y comptox dashboard (epa) dtxsid70203046 inchi inchi=1s/c20h22n2o3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17h,1-3,9-10h2,(h2,21,23)(h,22,24) ykey: rofvxgguiseham-uhfffaoysa-n yinchi=1/c20h22n2o3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17h,1-3,9-10h2,(h2,21,23)(h,22,24)key: rofvxgguiseham-uhfffaoyao smiles o=c(nc1ccccc1)oc2=cc=cc(c3=cc=cc(c(n)=o)=c3)=c2 properties chemical formula c20h22n2o3 molar mass 338.407 g·mol−1 except where otherwise noted, data are given for materials in their standard state (at 25 °c , 100 kpa). n verify (what is yn ?) infobox references preclinical studies have shown faah inhibitors to increase bdnf levels in the hippocampus and prefrontal cortex, highlighting their potential in addiction treatment as "enviromimetics". indeed, chauvet et al. found that chronic urb597 administration in rats "significantly reduces cocaine-seeking behaviour and cue- and stress-induced relapse". urb597 was at one point being developed by kadmus pharmaceuticals, inc. for clinical trials in humans.