jwh-210 jwh-210 jwh-210 is an analgesic chemical from the naphthoylindole family, which acts as a potent cannabinoid agonist at both the cb1 and cb2 receptors, with ki values of 0.46 nm at cb1 and 0.69 nm at cb2. it is one of the most potent 4-substituted naphthoyl derivatives in the naphthoylindole series, having a higher binding affinity (i.e. lower ki) at cb1 than both its 4-methyl and 4-n-propyl homologues jwh-122 (cb1 ki 0.69 nm) and jwh-182 (cb1 ki 0.65 nm) respectively, and than the 4-methoxy compound jwh-081 (cb1 ki 1.2 nm). it was discovered by and named after john w. huffman. jwh-210legal statuslegal status ca: schedule ii de: anlage ii (authorized trade only, not prescriptible) uk: class b illegal in sweden, i-n(poland) identifiers iupac name 4-ethylnaphthalen-1-yl-(1-pentylindol-3-yl)methanone cas number824959-81-1 y (jwh-210) 824960-02-3 (jwh-182)pubchem cid45270396chemspider24617616 nuniir18jyo04pycomptox dashboard (epa)dtxsid301010019 echa infocard100.233.380 chemical and physical dataformulac26h27nomolar mass369.508 g·mol−13d model (jsmol)interactive image smiles c4cccc2c4c(cc)ccc2c(=o)c(c3)c1ccccc1n3ccccc inchi inchi=1s/c26h27no/c1-3-5-10-17-27-18-24(22-13-8-9-14-25(22)27)26(28)23-16-15-19(4-2)20-11-6-7-12-21(20)23/h6-9,11-16,18h,3-5,10,17h2,1-2h3 nkey:laciuqlunacukc-uhfffaoysa-n n ny (what is this?) (verify) jwh-210 may be neurotoxic to animals when administered in high doses. legal status in the united states, all cb1 receptor agonists of the 3-(1-naphthoyl)indole class such as jwh-210 are schedule i controlled substances. jwh-210 and jwh-122 were banned in sweden on 1 october 2010 as hazardous goods harmful to health, after being identified as ingredients in "herbal" synthetic cannabis products. the substances jwh-210, jwh-122 and jwh-203 were classified as illegal drugs by the swedish government as of 1 september 2011. as of october 2015 jwh-210 is a controlled substance in china.