taltirelin taltirelin taltirelin (marketed under the tradename ceredist) is a thyrotropin-releasing hormone (trh) analog, which mimics the physiological actions of trh, but with a much longer half-life and duration of effects, and little development of tolerance following prolonged dosing. it has nootropic, neuroprotective and analgesic effects. taltirelinclinical dataother names(4s)-n--3-(3h-imidazol-4-yl)-1-oxopropan-2-yl]-1-methyl-2,6-dioxo-1,3-diazinane-4-carboxamideahfs/drugs.cominternational drug namesroutes ofadministrationoralatc codenoneidentifiers iupac name n--l-histidyl-l-prolinamide cas number103300-74-9 y 201677-75-0pubchem cid656609iuphar/bps2143chemspider102734 nuniidoz62mv6a5chebichebi:135653comptox dashboard (epa)dtxsid0043763 chemical and physical dataformulac17h31n7o9molar mass477.475 g·mol−13d model (jsmol)interactive image smiles cn1c(=o)c(nc1=o)c(=o)n(cc2=cn=cn2)c(=o)n3ccc3c(=o)n inchi inchi=1s/c17h23n7o5/c1-23-13(25)6-10(22-17(23)29)15(27)21-11(5-9-7-19-8-20-9)16(28)24-4-2-3-12(24)14(18)26/h7-8,10-12h,2-6h2,1h3,(h2,18,26)(h,19,20)(h,21,27)(h,22,29)/t10-,11-,12-/m0/s1 nkey:lqzaiazudwivpm-srvkxctjsa-n n ny (what is this?) (verify) taltirelin is primarily being researched for the treatment of spinocerebellar ataxia; limited research has also been carried out with regard to other neurodegenerative disorders, e.g., spinal muscular atrophy.