tezosentan tezosentan tezosentan is a non-selective eta and etb receptor antagonist. it acts as a vasodilator and was designed by actelion as a therapy for patients with acute heart failure. however, studies showed that tezosentan did not improve dyspnea or reduce the risk of fatal or nonfatal cardiovascular events. tezosentanclinical dataatc codenoneidentifiers iupac name n-pyrimidin-4-yl]-5-propan-2-ylpyridine-2-sulfonamide cas number180384-57-0 ypubchem cid151174chemspider133242 yunii64j9j55263chemblchembl61780 ycomptox dashboard (epa)dtxsid20170956 chemical and physical dataformulac27h27n9o6smolar mass605.624 g·mol−13d model (jsmol)interactive image smiles o=s(=o)(c1ncc(cc1)c(c)c)nc3nc(nc(occo)c3oc2ccccc2oc)c5ccnc(c4nnn4)c5 inchi inchi=1s/c27h27n9o6s/c1-16(2)18-8-9-22(29-15-18)43(38,39)34-26-23(42-21-7-5-4-6-20(21)40-3)27(41-13-12-37)31-24(30-26)17-10-11-28-19(14-17)25-32-35-36-33-25/h4-11,14-16,37h,12-13h2,1-3h3,(h,30,31,34)(h,32,33,35,36) ykey:tuywtltwnjozny-uhfffaoysa-n y (verify)