bd1063 bd1063 bd1063 or 1--4-methylpiperazine is a selective sigma receptor antagonist, with a reported binding affinity of ki = 9 ± 1 nm for the sigma-1 receptor and more than 49 times selectivity over the sigma-2 receptor. bd1063identifiers iupac name 1--4-methylpiperazine cas number150208-28-9chemspider499765comptox dashboard (epa)dtxsid70341674 echa infocard100.229.843 chemical and physical dataformulac13h18cl2n2molar mass273.20 g·mol−13d model (jsmol)interactive image smiles cn1ccn(cc1)ccc2ccc(c(c2)cl)cl inchi inchi=1s/c13h18cl2n2/c1-16-6-8-17(9-7-16)5-4-11-2-3-12(14)13(15)10-11/h2-3,10h,4-9h2,1h3key:suizrdjcbvpasy-uhfffaoysa-n consistent with other reported sigma receptor antagonists, pretreating swiss webster mice with bd1063 significantly decreases the convulsivity and lethality of cocaine. in other animal studies, bd1063 blocks the effects of mdma, and reduces alcohol intake in rodent models of alcoholism.