am-906 am-906 am-906 (part of the am cannabinoid series) is an analgesic drug which is a cannabinoid agonist. it is conformationally restricted by virtue of the double bond on its side chain, leading an increased affinity for and selectivity between cb1 and cb2 receptors. it is a potent and selective agonist for the cb1 cannabinoid receptor, with a ki of 0.8 nm at cb1 and 9.5 nm at cb2, a selectivity of almost 12x. am-906identifiers iupac name (6ar,9r,10ar)-3--9-(hydroxymethyl)-6,6-dimethyl-6a,7,8,9,10,10a-hexahydrobenzochromen-1-ol cas number180989-26-8 ypubchem cid10089808chemspider8174103 yuniiew1uq3b1y8chemblchembl127848 ychemical and physical dataformulac23h34o3molar mass358.522 g·mol−13d model (jsmol)interactive image smiles ccccc/c=c\c1=cc2=c(c3cc(ccc3c(o2)(c)c)co)c(=c1)o inchi inchi=1s/c23h34o3/c1-4-5-6-7-8-9-16-13-20(25)22-18-12-17(15-24)10-11-19(18)23(2,3)26-21(22)14-16/h8-9,13-14,17-19,24-25h,4-7,10-12,15h2,1-3h3/b9-8-/t17-,18-,19-/m1/s1 ykey:njikrwbguiykjm-forfbylssa-n y (verify) the corresponding e or trans isomer is am-905.