tiratricol tiratricol tiratricol (also known as triac or triiodothyroacetic acid) is a thyroid hormone analogue. triiodothyroacetic acid is also a physiologic thyroid hormone that is present in the normal organism in low concentrations. tiratricolclinical dataother names3,3',5-triiodothyroacetic acidtriacahfs/drugs.cominternational drug namesatc codeh03aa04 (who) d11ax08 (who)pharmacokinetic dataprotein bindingpresumed highmetabolismhepatic glucuronidationexcretionbiliaryidentifiers iupac name acetic acid cas number51-24-1 npubchem cid5803iuphar/bps2637drugbankdb03604 ychemspider5598 yunii29oq9eu4r1keggd07214 ychemblchembl41632 ycomptox dashboard (epa)dtxsid2045232 echa infocard100.000.079 chemical and physical dataformulac14h9i3o4molar mass621.935 g·mol−13d model (jsmol)interactive image smiles ic2cc(oc1c(i)cc(cc1i)cc(=o)o)ccc2o inchi inchi=1s/c14h9i3o4/c15-9-6-8(1-2-12(9)18)21-14-10(16)3-7(4-11(14)17)5-13(19)20/h1-4,6,18h,5h2,(h,19,20) ykey:uowzuvnaguaeqc-uhfffaoysa-n y ny (what is this?) (verify) uses it is indicated in the management of thyroid hormone resistance syndrome and is used, in combination with levothyroxine, to suppress thyroid-stimulating hormone production in patients with thyroid cancer. it has been investigated for use in reducing goiter. it has also shown some effectiveness in reducing the atrophy caused when using corticosteroids. tiratricol has also been widely marketed, under various trade names, as a weight loss aid. in 1999 and 2000, the united states food and drug administration and health canada both issued warnings to the public regarding the use of dietary supplements containing tiratricol. legal status tiratricol is not approved for sale in canada or the united states. it was once an approved drug in brazil, but its marketing authorization was suspended in 2003, effectively prohibiting its sale. tiratricol is still available in france for therapy of thyroid hormone resistance and adjuvant therapy of thyroid cancer. it is available as an orphan drug to be prescribed by registered specialists in europe.