fub-apinaca fub-apinaca fub-apinaca (also known as a-fubinaca according to the emccda framework for naming synthetic cannabinoids and fub-akb48) is an indazole-based synthetic cannabinoid that is presumed to be a potent agonist of the cb1 receptor and has been sold online as a designer drug. it is an analog of apinaca and 5f-apinaca where the pentyl chain has been replaced with fluorobenzyl. fub-apinacalegal statuslegal status ca: schedule ii de: npsg (industrial and scientific use only) uk: class b us: schedule i identifiers iupac name n-(adamantan-1-yl)-1--1h-indazole-3-carboxamide cas number2180933-90-6 ypubchem cid118796517chemspider30922497uniiof9q7ph4udchemical and physical dataformulac25h26fn3omolar mass403.501 g·mol−13d model (jsmol)interactive image smiles o=c(nc1(c2c3)c3c(c2)c1)c4=nn(cc5=cc=c(f)c=c5)c6=c4c=cc=c6 inchi inchi=1s/c25h26fn3o/c26-20-7-5-16(6-8-20)15-29-22-4-2-1-3-21(22)23(28-29)24(30)27-25-12-17-9-18(13-25)11-19(10-17)14-25/h1-8,17-19h,9-15h2,(h,27,30)/t17-,18+,19-,25?key:mwbhsnbpuskvdd-lpsayfbnsa-n pharmacology fub-apinaca acts as a full agonist with a binding affinity of 1.06 nm at cb1 and 0.174 nm at cb2 cannabinoid receptors. legal status in the united states, fub-apinaca was temporarily emergency scheduled by the dea in 2019. and made a permanent schedule i controlled substance nationwide on april 7, 2022. previously, it was illegal only in alabama (listed as fub-akb48). sweden's public health agency suggested classifying fub-apinaca as a hazardous substance on november 10, 2014.