a type that has been observed in multiple siblings in the same generation in several families, termed familial inflammatory sibm, but it is not passed on from generation to generation. there are also several very rare forms of hereditary inclusion body myopathy (hibm) that are linked to specific genetic defects and that are passed on from generation to generation, each inherited in different ways. management there is no standard course of treatment to slow or stop the progression of the disease as of 2019. sibm patients do not reliably respond to anti-inflammatory, immunosuppressant, or immunomodulatory medications. most of disease management is supportive care. prevention of falls is an important consideration. there is no consensus on exercise guidelines; however, physical therapy is recommended to teach the patient a home exercise program, to teach how to compensate during mobility-gait training with an assistive device, transfers and bed mobility. an exercise regimen preferentially minimizes a patient's risk of injury and corresponds to the patient's goals. other related disorders when sibm was originally described, the major feature noted was muscle inflammation. two other disorders were also known to display muscle inflammation, and sibm was classified along with them. they are dermatomyositis (dm) and polymyositis (pm) and all three illnesses were called idiopathic (of unknown origin) myositis or inflammatory myopathies. it appears that sibm and polymyositis share some features, especially the initial sequence of immune system activation, however, polymyositis comes on over weeks or months, does not display the subsequent muscle degeneration and protein abnormalities as seen in ibm, and as well, polymyositis tends to respond well to treatments, ibm does not. ibm is often confused with (misdiagnosed as) polymyositis. polymyositis that does not respond to treatment is likely ibm. dermatomyositis shares a number of similar physical symptoms and histopathological traits as polymyositis, but exhibits a skin rash not seen in polymyositis or sibm. it may have different root causes unrelated to either polymyositis or sibm. mutations in valosin-containing protein (vcp) cause multisystem proteinopathy (msp), which can present (among others) as a rare form of inclusion body myopathy. epidemiology prevalence of disease in a rigorous meta-analysis in 2017 was 46 patients per million. the earliest published prevalence was in 2000 and put at 5 per million. a 2017 study in ireland reported 112 per million. it is not believed that the disease prevalence is increasing with time, but rather diagnostics and reporting are improving. estimates of the mean age of onset range from 61 to 68 years old. society and culture in the biographical drama film father stu, the protagonist, a boxer-turned-catholic priest, has sibm.