anileridine anileridine anileridine (trade name: leritine) is a synthetic analgesic drug and is a member of the piperidine class of analgesic agents developed by merck & co. in the 1950s. it differs from pethidine (meperidine) in that the n-methyl group of meperidine is replaced by an n-aminophenethyl group, which increases its analgesic activity. anileridineclinical datatrade namesleritineahfs/drugs.commonographroutes ofadministrationtablets, injectionatc coden01ah05 (who) legal statuslegal status au: s8 (controlled drug) ca: schedule i de: anlage i (authorized scientific use only) us: schedule ii pharmacokinetic dataprotein binding> 95%metabolismhepaticidentifiers iupac name ethyl 1--4-phenylpiperidine-4-carboxylate cas number144-14-9 ypubchem cid8944iuphar/bps7115drugbankdb00913 ychemspider8600 yunii71q1a3o279keggd02941 ychebichebi:61203 ychemblchembl1201347 ncomptox dashboard (epa)dtxsid8022610 chemical and physical dataformulac22h28n2o2molar mass352.478 g·mol−13d model (jsmol)interactive imagemelting point83 °c (181 °f) smiles o=c(occ)c3(c1ccccc1)ccn(ccc2ccc(n)cc2)cc3 inchi inchi=1s/c22h28n2o2/c1-2-26-21(25)22(19-6-4-3-5-7-19)13-16-24(17-14-22)15-12-18-8-10-20(23)11-9-18/h3-11h,2,12-17,23h2,1h3 ykey:lkyqlawmnbfnjt-uhfffaoysa-n y ny (what is this?) (verify) anileridine is no longer manufactured in the us or canada. anileridine is in schedule ii of the controlled substances act 1970 of the united states as acscn 9020 with a zero aggregate manufacturing quota as of 2014. the free base conversion ratio for salts includes 0.83 for the dihydrochloride and 0.73 for the phosphate. it is also under international control per un treaties. administration as tablets or injection. pharmacokinetics anileridine usually takes effect within 15 minutes of either oral or intravenous administration, and lasts 2–3 hours. it is mostly metabolized by the liver.