am-11245 am-11245 am-11245 is a drug which is a cannabinoid agonist from the classical cannabinoid family. it has high affinity and efficacy at both the cb1 and cb2 cannabinoid receptors, with a ki of 0.4nm at both cb1 and cb2, and an ec50 of ~0.06nm at cb1 and 0.2nm at cb2, making it one of the most potent cannabinoid agonists identified to date. am-11245identifiers iupac name 8-chromen-3-yl]-8-methylnonanenitrile chemical and physical dataformulac26h39no3molar mass413.602 g·mol−13d model (jsmol)interactive image smiles cc1(c)oc2=c(31cc(co)c3)c(o)=cc(c(c)(c)ccccccc#n)=c2 inchi inchi=1s/c26h39no3/c1-25(2,12-8-6-5-7-9-13-27)19-15-22(29)24-20-14-18(17-28)10-11-21(20)26(3,4)30-23(24)16-19/h15-16,18,20-21,28-29h,5-12,14,17h2,1-4h3/t18-,20-,21-/m1/s1key:igsaqgjqmkotag-hmxcviknsa-n