syrosingopine syrosingopine syrosingopine is a drug, derived from reserpine. it is used (since about 1960) to treat hypertension. syrosingopineclinical datatrade namessingoserpatc codec02la09 (who) (combination with diuretics)identifiers iupac name methyl (3β,16β,17α,18β,20α)-18-(oxy)-11,17-dimethoxyyohimban-16-carboxylate cas number84-36-6pubchem cid6769chemspider6511uniippg46jf0egkeggd01659comptox dashboard (epa)dtxsid9023629 echa infocard100.001.388 chemical and physical dataformulac35h42n2o11molar mass666.724 g·mol−13d model (jsmol)interactive image smiles ccoc(=o)oc1c(cc(cc1oc)c(=o)o2c3cn4ccc5c6ccc(cc6c54c3(2oc)c(=o)oc)oc)oc inchi inchi=1s/c35h42n2o11/c1-7-46-35(40)48-31-26(42-3)12-18(13-27(31)43-4)33(38)47-28-14-19-17-37-11-10-22-21-9-8-20(41-2)15-24(21)36-30(22)25(37)16-23(19)29(32(28)44-5)34(39)45-6/h8-9,12-13,15,19,23,25,28-29,32,36h,7,10-11,14,16-17h2,1-6h3/t19-,23+,25-,28-,29+,32+/m1/s1key:zcdnrppfbqdqhr-ssyatkpksa-n research a combination of the diabetes drug metformin and syrosingopine killed tumor cells in blood samples from leukemia patients, while it did not damage blood cells in samples from healthy patients. the combination of metformin and syrosingopine also reduced or eliminated tumors in mice with malignant liver cancer. the drugs interfere with the cancer cells' glucose (i.e. energy) supply and utilization. cancer cells have much higher energy requirements than normal cells, making them vulnerable when there is a reduction in the available energy supply. syrosingopine inhibits the degradation of sugars within the cells.