ichthyosis acquisita ichthyosis acquisita ichthyosis acquisita is a disorder clinically and histologically similar to ichthyosis vulgaris.: 565 ichthyosis acquisitaother namesacquired ichthyosisspecialtydermatology presentation associated conditions the development of ichthyosis in adulthood can be a manifestation of systemic disease, and it has been described in association with malignancies, drugs, endocrine and metabolic disease, hiv, infection, and autoimmune conditions.: 494 it usually is associated with people who have hodgkin's disease but it is also occurs in people with mycosis fungoides, other malignant sarcomas, kaposi's sarcoma and visceral carcinomas. it can occur in people with leprosy, aids, tuberculosis, and typhoid fever.