notifiable diseases in the united states notifiable diseases in the united states in the united states, the national notifiable disease surveillance system (nndss) is responsible for sharing information regarding notifiable diseases. as of 2020, the following are the notifiable diseases in the us as mandated by the centers for disease control and prevention: notifiable infectious diseases anthrax arboviral diseases, neuroinvasive and non-neuroinvasive california serogroup virus diseases chikungunya virus disease eastern equine encephalitis virus disease powassan virus disease saint louis encephalitis virus disease west nile virus disease western equine encephalitis virus disease babesiosis botulism botulism, foodborne botulism, infant botulism, wound botulism, other brucellosis campylobacteriosis candida auris carbapenemase producing carbapenem-resistant enterobacteriaceae (cp-cre) cp-cre, enterobacter spp. cp-cre, escherichia coli (e. coli) cp-cre, klebsiella spp. chancroid chlamydia trachomatis infection cholera coccidioidomycosis congenital syphilis syphilitic stillbirth coronavirus disease 2019 (covid-19) cryptosporidiosis cyclosporiasis dengue virus infections dengue dengue-like illness severe dengue diphtheria ehrlichiosis and anaplasmosis anaplasma phagocytophilum infection ehrlichia chaffeensis infection ehrlichia ewingii infection undetermined human ehrlichiosis/anaplasmosis giardiasis gonorrhea haemophilus influenzae, invasive disease hansen's disease hantavirus infection, non-hantavirus pulmonary syndrome hantavirus pulmonary syndrome hemolytic uremic syndrome, post-diarrheal hepatitis a, acute hepatitis b, acute hepatitis b, chronic hepatitis b, perinatal virus infection hepatitis c, acute hepatitis c, chronic hepatitis c, perinatal infection hiv infection influenza-associated pediatric mortality invasive pneumococcal disease legionellosis leptospirosis listeriosis lyme disease malaria measles meningococcal disease mumps novel influenza a virus infections pertussis plague poliomyelitis, paralytic poliovirus infection, nonparalytic psittacosis q fever q fever, acute q fever, chronic rabies, animal rabies, human rubella rubella, congenital syndrome salmonella paratyphi infection (salmonella enterica serotypes paratyphi a, b , and c ) salmonella typhi infection (salmonella enterica serotype typhi) salmonellosis severe acute respiratory syndrome-associated coronavirus disease shiga toxin-producing escherichia coli shigellosis smallpox spotted fever rickettsiosis streptococcal toxic shock syndrome syphilis syphilis, primary syphilis, secondary syphilis, early non-primary non-secondary syphilis, unknown or late tetanus toxic shock syndrome (other than streptococcal) trichinellosis tuberculosis tularemia vancomycin-intermediate staphylococcus aureus and vancomycin-resistant staphylococcus aureus varicella varicella deaths vibriosis viral hemorrhagic fever crimean-congo hemorrhagic fever virus ebola virus lassa virus lujo virus marburg virus new world arenavirus – guanarito virus new world arenavirus – junin virus new world arenavirus – machupo virus new world arenavirus – sabia virus yellow fever zika virus disease and zika virus infection zika virus disease, congenital zika virus disease, non-congenital zika virus infection, congenital zika virus infection, non-congenital notifiable non-infectious diseases cancer carbon monoxide poisoning lead, elevated blood levels lead, elevated blood levels, children (<16 years) lead, elevated blood levels, adult (≥16 years) pesticide-related illness and injury, acute silicosis notifiable outbreaks foodborne disease outbreak waterborne disease outbreak