list of chemotherapeutic agents list of chemotherapeutic agents this is a list of chemotherapeutic agents, also known as cytotoxic agents or cytostatic drugs, that are known to be of use in chemotherapy for cancer. this list is organized by type of agent, although the subsections are not necessarily definitive and are subject to revision. each drug is listed once (at present), though it might fall in more than one subsection. a full alphabetical listing is included after the categorical listing. the agents in this list are often combined into chemotherapy agent for polychemotherapy (combination chemotherapy). for example, the chop regimen consists of cyclophosphamide, doxorubicin, vincristine and prednisone. besides chemotherapy, medical oncology (pharmacotherapy for cancer) includes several noncytotoxic classes of therapy, such as hormonal therapy and targeted therapy (biologic therapy). those agents are described in the relevant articles. alkylating agents altretamine bendamustine busulfan carboquone carmustine chlorambucil chlormethine chlorozotocin cyclophosphamide dacarbazine fotemustine ifosfamide lomustine melphalan melphalan flufenamide mitobronitol nimustine nitrosoureas pipobroman ranimustine semustine streptozotocin temozolomide thiotepa treosulfan triaziquone triethylenemelamine trofosfamide uramustine anthracyclines main article: anthracycline aclarubicin daunorubicin doxorubicin epirubicin idarubicin mitoxantrone pirarubicin valrubicin zorubicin cytoskeletal disruptors (taxanes) main article: taxane abraxane cabazitaxel docetaxel larotaxel paclitaxel taxotere tesetaxel epothilones ixabepilone histone deacetylase inhibitors vorinostat romidepsin inhibitors of topoisomerase i main article: topoisomerase inhibitor belotecan camptothecin exatecan gimatecan irinotecan topotecan inhibitors of topoisomerase ii etoposide teniposide tafluposide kinase inhibitors main article: kinase inhibitor bortezomib erlotinib gefitinib imatinib vemurafenib vismodegib nucleotide analogs and precursor analogs azacitidine azathioprine capecitabine cytarabine doxifluridine fluorouracil gemcitabine hydroxyurea mercaptopurine methotrexate tioguanine (formerly thioguanine) peptide antibiotics main article: antimicrobial peptides actinomycin bleomycin platinum-based agents main article: platinum-based antineoplastic carboplatin cisplatin dicycloplatin oxaliplatin nedaplatin satraplatin retinoids alitretinoin bexarotene tretinoin vinca alkaloids and derivatives vinblastine vincristine vindesine vinorelbine full alphabetical listing abraxane actinomycin alitretinoin all-trans retinoic acid altretamine azacitidine azathioprine belotecan bendamustine bexarotene bleomycin bortezomib busulfan cabazitaxel camptothecin carboplatin carboquone carmustine capecitabine cisplatin chlorambucil chlormethine chlorozotocin cyclophosphamide cytarabine dacarbazine daunorubicin docetaxel doxifluridine doxorubicin epirubicin epothilone erlotinib etoposide exatecan fluorouracil fotemustine gefitinib gemcitabine gimatecan hydroxyurea idarubicin ifosfamide imatinib irinotecan ixabepilone larotaxel lomustine melphalan melphalan flufenamide mercaptopurine methotrexate mitobronitol mitomycin c mitoxantrone nimustine nitrosoureas oxaliplatin paclitaxel pemetrexed pipobroman ranimustine romidepsin semustine streptozotocin tafluposide taxotere temozolomide tesetaxel teniposide thiotepa tioguanine topotecan treosulfan tretinoin triaziquone triethylenemelamine valrubicin vemurafenib vinblastine vincristine vindesine vinorelbine vismodegib vorinostat comprehensive table intracellular chemotherapeutic agents / antineoplastic agents (l01)sps/mis(m phase)block microtubule assembly vinca alkaloids (vinblastine# vincristine# vindesine vinflunine§ vinorelbine#) block microtubule disassembly taxanes (cabazitaxel docetaxel# larotaxel ortataxel† paclitaxel# tesetaxel) epothilones (ixabepilone) dna replicationinhibitordna precursors/antimetabolites(s phase)folic acid dihydrofolate reductase inhibitor (aminopterin methotrexate# pemetrexed pralatrexate) thymidylate synthase inhibitor (pemetrexed raltitrexed) purine adenosine deaminase inhibitor (pentostatin) halogenated/ribonucleotide reductase inhibitors (cladribine clofarabine fludarabine) nelarabine thiopurine (mercaptopurine# tioguanine#) pyrimidine thymidylate synthase inhibitor (capecitabine# carmofur doxifluridine floxuridine fluorouracil# tegafur (+gimeracil/oteracil)) dna polymerase inhibitor (cytarabine# +daunorubicin) ribonucleotide reductase inhibitor (gemcitabine#) hypomethylating agent (azacitidine decitabine) deoxyribonucleotide ribonucleotide reductase inhibitor (hydroxycarbamide#) topoisomerase inhibitors(s phase)i camptotheca (belotecan camptothecin cositecan† etirinotecan pegol† exatecan gimatecan irinotecan# lurtotecan‡ rubitecan‡ silatecan§ topotecan) ii podophyllum (etoposide# teniposide) ii+intercalation anthracyclines (aclarubicin amrubicin† daunorubicin# (+cytarabine) doxorubicin# epirubicin idarubicin pirarubicin valrubicin zorubicin) anthracenediones (mitoxantrone losoxantrone pixantrone) amsacrine bisantrene crisnatol menogaril§ crosslinking of dna(ccns)alkylating nitrogen mustards: bendamustine# chlormethine cyclophosphamide# (ifosfamide# trofosfamide) chlorambucil# melphalan (melphalan flufenamide) prednimustine uramustine nitrosoureas: carmustine fotemustine lomustine (semustine) nimustine ranimustine streptozocin alkyl sulfonates: busulfan (mannosulfan treosulfan) aziridines: carboquone thiotepa triaziquone triethylenemelamine platinum-based carboplatin# cisplatin# dicycloplatin nedaplatin oxaliplatin# satraplatin nonclassical altretamine hydrazines (procarbazine#) etoglucid mitobronitol pipobroman triazenes (dacarbazine# mitozolomide§ temozolomide) intercalation streptomyces (dactinomycin# bleomycin# mitomycins plicamycin) photosensitizers/pdt aminolevulinic acid efaproxiral methyl aminolevulinate padeliporfin porphyrin derivatives (porfimer sodium talaporfin temoporfin verteporfin) otherenzyme inhibitors fi (tipifarnib§) cdk inhibitors (abemaciclib alvocidib† palbociclib ribociclib seliciclib†) pri bortezomib carfilzomib oprozomib ixazomib phi (anagrelide) impdi (tiazofurin§) li (masoprocol) parp inhibitor (niraparib +abiraterone acetate olaparib rucaparib) hdac (belinostat entinostat panobinostat romidepsin vorinostat) piki (pi3k) (alpelisib copanlisib duvelisib idelalisib umbralisib‡) receptor antagonists era (atrasentan) retinoid x receptor (bexarotene) sex steroid (testolactone) other/ungrouped adagrasib aflibercept arsenic trioxide asparagine depleters (asparaginase#/pegaspargase) axicabtagene ciloleucel belzutifan bexarotene brexucabtagene autoleucel celecoxib ciltacabtagene autoleucel demecolcine denileukin diftitox elesclomol§ elsamitrucin enasidenib epacadostat eribulin estramustine phosphate glasdegib idecabtagene vicleucel ivosidenib lonidamine lucanthone lurbinectedin mitoguazone mitotane oblimersen† omacetaxine mepesuccinate plitidepsin retinoids (alitretinoin selinexor sitimagene ceradenovec sotorasib tagraxofusp talimogene laherparepvec tazemetostat tiazofurine tigilanol tiglate tisagenlecleucel trabectedin tretinoin#) veliparib venetoclax verdinexor vosaroxin #who-em ‡withdrawn from market clinical trials: †phase iii §never to phase iii this article is issued from wikipedia. the text is licensed under creative commons - attribution - sharealike. additional terms may apply for the media files.