tiflorex tiflorex tiflorex, formerly known as flutiorex, is a stimulant amphetamine. its most pronounced effect is in suppression of appetite; it has little effect on pulse rate, sleep, or mood. it was found to be twice as potent an anorectic as fenfluramine. tiflorexclinical dataatc codenoneidentifiers iupac name (rs)-n-ethyl-1-propan-2-amine cas number53993-67-2 ypubchem cid173669chemspider151574 nuniieg3b69dfq5chemical and physical dataformulac12h16f3nsmolar mass263.32 g·mol−13d model (jsmol)interactive imagechiralityracemic mixture smiles ccnc(c)cc1cccc(c1)sc(f)(f)f inchi inchi=1s/c12h16f3ns/c1-3-16-9(2)7-10-5-4-6-11(8-10)17-12(13,14)15/h4-6,8-9,16h,3,7h2,1-2h3 nkey:hnonsdncrnutct-uhfffaoysa-n n ny (what is this?) (verify) sl 72.340-d was cited to be 4x the anorectant potency of fenfluramine (ed50=1.4 mg/kg vs 5.6 mg/kg). synthesis patent: the rosenmund reduction of 3-(trifluoromethylthio)benzoyl chloride (1) gave 3-((trifluoromethyl)thio)benzaldehyde (2). henry reaction with nitroethane led to 1-(2-nitroprop-1-en-1-yl)-3-benzene (3). with the aid of iron catalyst in concentrated hcl acid there occurred fgi into 1-(3'-trifluoromethylthiophenyl)-2-propanone, cid:21325269 (4'). reductive amination with ethylamine and formic acid as the reductant completed the synthesis of tiflorex (5).