alimemazine alimemazine alimemazine (inn), also known as trimeprazine, (brand names nedeltran, panectyl, repeltin, therafene, theraligene, theralen, theralene, vallergan, vanectyl, and temaril), commonly provided as a tartrate salt, is a phenothiazine derivative that is used as an antipruritic (it prevents itching from causes such as eczema or poison ivy, by acting as an antihistamine). it also acts as a sedative, hypnotic, and antiemetic for prevention of motion sickness. although it is structurally related to drugs such as chlorpromazine, it is not used as an antipsychotic. in the russian federation, it is marketed under the brand name teraligen for the treatment of anxiety disorders (including gad), organic mood disorders, sleep disturbances, personality disorders accompanied by asthenia and depression, somatoform autonomic dysfunction and various neuroses. alimemazineclinical dataother namestrimeprazine (ban uk), trimeprazine (usan us)ahfs/drugs.cominternational drug namespregnancycategory au: c routes ofadministrationoralatc coder06ad01 (who) legal statuslegal status uk: pom (prescription only) pharmacokinetic datametabolismhepaticelimination half-life4.78 ± 0.59 hoursidentifiers iupac name n,n,2-trimethyl-3-phenothiazin-10-yl-propan-1-amine cas number84-96-8 ypubchem cid5574iuphar/bps7237drugbankdb01246 ychemspider5373 yunii76h78mjj52keggd07125 ychemblchembl829 ycomptox dashboard (epa)dtxsid9023708 echa infocard100.001.434 chemical and physical dataformulac18h22n2smolar mass298.45 g·mol−13d model (jsmol)interactive image smiles s2c1ccccc1n(c3c2cccc3)cc(c)cn(c)c inchi inchi=1s/c18h22n2s/c1-14(12-19(2)3)13-20-15-8-4-6-10-17(15)21-18-11-7-5-9-16(18)20/h4-11,14h,12-13h2,1-3h3 ykey:zzhlyydviopzbe-uhfffaoysa-n y (verify) alimemazine is not approved for use in humans in the united states. the combination of alimemazine and prednisolone (commonly sold under the brand name temaril-p) is licensed as an antipruritic and antitussive in dogs.