stibophen stibophen stibophen is an anthelmintic originally developed by bayer that is used as a treatment for schistosomiasis by intramuscular injection. it is classified as a trivalent antimony compound. brand names include fouadin/fuadin (named in honor of fuad i of egypt, who had enthusiastically supported its research and development). stibophenclinical dataatc codep02bx03 (who) identifiers iupac name pentasodium 2-(2-oxido-3,5-disulfonatophenoxy)-1,3,2-benzodioxastibole-5,7-disulfonate cas number23940-36-5 ypubchem cid16683091chemspider17615576uniief31ljy4kncomptox dashboard (epa)dtxsid10946763 echa infocard100.007.630 chemical and physical dataformulac12h4na5o16s4sbmolar mass769.10 g·mol−13d model (jsmol)interactive image smiles c1=c(c=c2c(=c1s(=o)(=o))o(o2)oc3=cc(=cc(=c3)s(=o)(=o))s(=o)(=o))s(=o)(=o)..... inchi inchi=1s/2c6h6o8s2.5na.7h2o.sb/c2*7-4-1-3(15(9,10)11)2-5(6(4)8)16(12,13)14;;;;;;;;;;;;;/h2*1-2,7-8h,(h,9,10,11)(h,12,13,14);;;;;;7*1h2;/q;;5*+1;;;;;;;;+3/p-8key:zdduxabbratyfs-uhfffaoysa-f (verify) mechanism of action stibophen inhibits the enzyme phosphofructokinase, which the worms need for glycolysis, at least partly by binding to the sulfhydryl (–sh) group of the enzyme. inhibiting glycolysis paralyzes the worms, which lose their hold on the wall of mesenteric veins and undergo hepatic shift, die, and are phagocytosed by liver cells.