pwz-029 pwz-029 pwz-029 is a benzodiazepine derivative drug with nootropic effects developed by wisys, it acts as a subtype-selective, mixed agonist-inverse agonist at the benzodiazepine binding site on the gabaa receptor, acting as a partial inverse agonist at the α5 subtype and a weak partial agonist at the α3 subtype. this gives it a mixed pharmacological profile, producing at low doses memory-enhancing effects but with no convulsant or anxiogenic effects or muscle weakness, although at higher doses it produces some sedative effects. pwz-029identifiers iupac name 8-chloro-3-(methoxymethyl)-5-methyl-4h-imidazobenzodiazepin-6-one pubchem cid9971547chemspider8147139 nchemblchembl45346 nchemical and physical dataformulac14h14cln3o2molar mass291.74 g·mol−13d model (jsmol)interactive image smiles clc1=cc=c2c(c(n(cc3=c(coc)n=cn32)c)=o)=c1 inchi inchi=1s/c14h14cln3o2/c1-17-6-13-11(7-20-2)16-8-18(13)12-4-3-9(15)5-10(12)14(17)19/h3-5,8h,6-7h2,1-2h3 nkey:fxidxtimkaebgy-uhfffaoysa-n n ny (what is this?) (verify)