central veins of liver central veins of liver in microanatomy, the central veins of liver (or central venules) are veins found at the center of hepatic lobules (one vein at each lobule center). central veins of livera single lobule of the liver of a pig. x 60. (central vein not labeled, though region is visible. central vein would be a single vein at the center of the lobule.)human central veindetailsdrains fromliver sinusoiddrains tohepatic veinsidentifierslatinvenae centrales hepatista98a05.8.01.059ta23065fma71629anatomical terminology they receive the blood mixed in the liver sinusoids and return it to circulation via the hepatic veins. the circulation of venous blood is: portal vein (which is formed by the joining of the superior mesenteric vein with the splenic vein) drains into the sinusoids of the liver, these all drain into the central veins of liver which drain into the hepatic vein to be returned to ivc.