sincalide sincalide sincalide (inn) is a cholecystokinetic drug administered by injection to aid in diagnosing disorders of the gallbladder and pancreas. it is the 8-amino acid c-terminal fragment of cholecystokinin, and also known as cck-8. sincalideclinical dataother names1-de(5-oxo-l-proline)-2-de-l-glutamine-5-l-methioninecaerulein, 3--3-(4-sulfooxyphenyl)propanoyl]amino]-4-methylsulfanyl-butanoyl]amino]acetyl]amino]-3-(1h-indol-3-yl)propanoyl]amino]-4-methylsulfanyl-butanoyl]amino]-3-propanoic acidahfs/drugs.commicromedex detailed consumer informationroutes ofadministrationintravenousatc codev04cc03 (who) legal statuslegal status uk: available on a named-patient basis us: ℞-only identifiers iupac name α-aspartyl-o-sulfotyrosylmethionylglycyltryptophylmethionyl-α-aspartylphenylalaninamide cas number25126-32-3 ypubchem cid32800iuphar/bps864chemspider8009168 nuniim03giq7z6pkeggd05845 ychemblchembl1121 ncomptox dashboard (epa)dtxsid7048617 echa infocard100.042.384 chemical and physical dataformulac49h62n10o16s3molar mass1143.27 g·mol−13d model (jsmol)interactive image smiles cscc(c(=o)ncc(=o)n(cc1=cnc2=cc=cc=c21)c(=o)n(ccsc)c(=o)n(cc(=o)o)c(=o)n(cc3=cc=cc=c3)c(=o)n)nc(=o)(cc4=cc=c(c=c4)os(=o)(=o)o)nc(=o)(cc(=o)o)n inchi inchi=1s/c49h62n10o16s3/c1-76-18-16-34(55-47(69)37(58-44(66)32(50)23-41(61)62)21-28-12-14-30(15-13-28)75-78(72,73)74)45(67)53-26-40(60)54-38(22-29-25-52-33-11-7-6-10-31(29)33)48(70)56-35(17-19-77-2)46(68)59-39(24-42(63)64)49(71)57-36(43(51)65)20-27-8-4-3-5-9-27/h3-15,25,32,34-39,52h,16-24,26,50h2,1-2h3,(h2,51,65)(h,53,67)(h,54,60)(h,55,69)(h,56,70)(h,57,71)(h,58,66)(h,59,68)(h,61,62)(h,63,64)(h,72,73,74)/t32-,34-,35-,36-,37-,38-,39-/m0/s1 nkey:iztqolkuzkxirv-yrvfcxmdsa-n n ny (what is this?) (verify) common adverse effects following administration include abdominal discomfort and nausea. these effects are more pronounced following rapid infusion. clinical use indications sincalide may be used to stimulate gallbladder contraction, as may be assessed by contrast agent cholecystography or ultrasonography, or to obtain by duodenal aspiration a sample of concentrated bile for analysis of cholesterol, bile salts, phospholipids, and crystals. it can also be used to stimulate pancreatic secretion (especially in conjunction with secretin) prior to obtaining a duodenal aspirate for analysis of enzyme activity, composition, and cytology. in some instances it is used to accelerate the transit of a barium meal through the small bowel, thereby decreasing the time and-extent of radiation associated with fluoroscopy and x-ray examination of the intestinal tract.