glycoproteinosis glycoproteinosis glycoproteinosis are lysosomal storage diseases affecting glycoproteins, resulting from defects in lysosomal function. the term is sometimes reserved for conditions involving degradation of glycoproteins. glycoproteinosisspecialtyendocrinology types (e77.0) defects in post-translational modification of lysosomal enzymes mucolipidosis ii (i-cell disease) mucolipidosis iii (pseudo-hurler polydystrophy) (e77.1) defects in glycoprotein degradation aspartylglucosaminuria fucosidosis mannosidosis sialidosis (mucolipidosis i) another type, recently characterized, is galactosialidosis.