brodmann area 28 brodmann area 28 brodmann area 28 is a subdivision of the cerebral cortex defined on the basis of cytoarchitecture. it is located on the medial aspect of the temporal lobe and is part of the entorhinal cortex (brodmann-1909). brodmann area 28medial surface of the brain with brodmann's areas numbered.detailsidentifierslatinarea entorhinalis ventralisneuronames1030neurolex idbirnlex_2709fma68625anatomical terms of neuroanatomy human in humans, brodmann area 28, and brodmann area 34 together constitute approximately the entorhinal cortex (brodmann-1909). guenon brodmann regarded the location of area 28 adjacent to the hippocampus as imprecisely represented in the illustration of the cortex of the guenon brain in brodmann-1909. it is located on the medial aspect of the temporal lobe. distinctive features (brodmann-1905) the molecular layer (i) is unusually wide; the external granular layer (ii) contains nests of, for the most part, multipolar cells: the external pyramidal layer (iii) contains medium-sized pyramidal cells which merge with cells of the internal pyramidal layer (v); a clear cell free zone represents sublayer 5b of layer v; the multiform layer is wide and has a less clear two sublayer structure; the internal granular layer (iv) is totally absent.