4-acetoxy-det 4-acetoxy-det 4-acetoxy-det (4-acetoxy-n,n-diethyltryptamine), also known as ethacetin, ethylacybin or 4-aco-det, is a psychedelic tryptamine. it was first synthesized in 1958 by albert hofmann in the sandoz lab. 4-acetoxy-detlegal statuslegal status de: npsg (industrial and scientific use only) uk: class a identifiers iupac name 3-(2-diethylaminoethyl)-1h-indol-4-yl acetate cas number1135424-15-5 npubchem cid24801867chemspider21106239 yunii43u8799479comptox dashboard (epa)dtxsid60647359 chemical and physical dataformulac16h22n2o2molar mass274.364 g·mol−13d model (jsmol)interactive image smiles cc(oc1=cc=cc2=c1c(ccn(cc)cc)=cn2)=o inchi inchi=1s/c16h22n2o2/c1-4-18(5-2)10-9-13-11-17-14-7-6-8-15(16(13)14)20-12(3)19/h6-8,11,17h,4-5,9-10h2,1-3h3 ykey:odvlayuxiambfn-uhfffaoysa-n n ny (what is this?) (verify) it is expected that the compound is quickly hydrolyzed into the free phenolic 4-ho-det by serum esterases, but human studies concerning the metabolic fate of this drug are lacking. dosage 4-acetoxy-det is orally active, and dosages of 10–25 mg are common. effects last 4–6 hours. the free base is also active when smoked in a dose range of 5–20 mg. smoking 4-acetoxy-det greatly speeds up the onset; peak effects are experienced within 10 minutes, and are usually over within 1 hour. drug prohibition laws sweden sveriges riksdags health ministry statens folkhälsoinstitut classified 4-aco-det as "health hazard" under the act lagen om förbud mot vissa hälsofarliga varor (translated act on the prohibition of certain goods dangerous to health) as of nov 1, 2005, in their regulation sfs 2005:733 listed as 4-acetoxi-n,n-dietyltryptamin (4-aco-det), making it illegal to sell or possess.