chondrodysplasia blomstrand chondrodysplasia blomstrand chondrodysplasia blomstrand is a rare disorder caused by mutation of the parathyroid hormone receptor resulting in the absence of a functioning pthr1. it results in ossification of the endocrine system and intermembraneous tissues and advanced skeletal maturation. chondrodysplasia blomstrandother namesblomstrand's lethal chondrodysplasiathis condition is inherited in an autosomal recessive manner.