mestilbol mestilbol mestilbol (brand name monomestro or monomestrol), also known as diethylstilbestrol monomethyl ether, is a synthetic nonsteroidal estrogen of the stilbestrol group related to diethylstilbestrol. it was developed by wallace & tiernan company, patented in 1940, and introduced for medical use in the 1940s, but is now no longer marketed. mestilbol was available both as oral tablets and in oil for intramuscular injection. the drug is gradually demethylated in the body into diethylstilbestrol and hence is a prodrug of diethylstilbestrol. mestilbol is a highly active estrogen, although somewhat less so than diethylstilbestrol, but is longer-lasting in comparison. mestilbolclinical datatrade namesmonomestro, monomestrolother namesmonomethylstilbestrol; diethylstilbestrol monomethyl etherdrug classnonsteroidal estrogen; estrogen etheridentifiers iupac name 4-phenol cas number18839-90-2pubchem cid3032340chemspider2297337uniin44u12uw5nchebichebi:34702comptox dashboard (epa)dtxsid7022469 chemical and physical dataformulac19h22o2molar mass282.383 g·mol−13d model (jsmol)interactive image smiles ccc(=c(cc)c1=cc=c(c=c1)oc)c2=cc=c(c=c2)o inchi inchi=1s/c19h22o2/c1-4-18(14-6-10-16(20)11-7-14)19(5-2)15-8-12-17(21-3)13-9-15/h6-13,20h,4-5h2,1-3h3/b19-18+key:ckmdpzmwuzdkai-vhebqxmusa-n