8,9-dehydroestrone 8,9-dehydroestrone 8,9-dehydroestrone, or δ8-estrone, also known as estra-1,3,5(10),8-tetraen-3-ol-17-one, is a naturally occurring estrogen found in horses which is closely related to equilin, equilenin, and estrone, and, as the 3-sulfate ester sodium salt, is a minor constituent (3.5%) of conjugated estrogens (premarin). it produces 8,9-dehydro-17β-estradiol as an important active metabolite, analogously to conversion of estrone or estrone sulfate into estradiol. the compound was first described in 1997. in addition to 8,9-dehydroestrone and 8,9-dehydro-17β-estradiol, 8,9-dehydro-17α-estradiol is likely also to be present in conjugated estrogens, but has not been identified at this time. 8,9-dehydroestroneclinical dataother namesδ8-estrone; estra-1,3,5(10),8-tetraen-3-ol-17-oneroutes ofadministrationby mouthdrug classestrogenidentifiers iupac name (13s,14s)-3-hydroxy-13-methyl-7,11,12,14,15,16-hexahydro-6h-cyclopentaphenanthren-17-one cas number474-87-3pubchem cid6451472chemspider4953937unii7c1n8rkg9fcomptox dashboard (epa)dtxsid40197125 chemical and physical dataformulac18h20o2molar mass268.356 g·mol−13d model (jsmol)interactive image smiles c12ccc3=c(1ccc2=o)ccc4=c3c=cc(=c4)o inchi inchi=1s/c18h20o2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,16,19h,2,4,6-9h2,1h3/t16-,18-/m0/s1key:ougsrcwshmwpqe-wmzopiptsa-n