surgical sealant film surgical sealant film a surgical sealant film is an implantable medical device used during surgery. it is a preformed flexible patch that is applied to supplement sutures and surgical staples to seal tissues and prevent leaks of fluid (including blood and cerebrospinal fluid) and air. use of a surgical sealant film to reinforce and seal gaps in the dura mater. the sealant film is synthetic and incorporates absorbable polymers, including poly(lactide-co-glycolide). the polymeric components impart structural and adhesive properties with the sealing effect achieved by incorporation of a bioadhesive polymer. this forms a covalent bond to primary amines present on the tissue surfaces. in turn this results in the film rapidly becoming effective in providing a form of secondary wound closure. the film can be used for sealing the dura mater, preventing blood loss in general surgery and eliminating air leaks following lung resection.