adb-fubinaca adb-fubinaca adb-fubinaca is a designer drug identified in synthetic cannabis blends in japan in 2013. in 2018, it was the third-most common synthetic cannabinoid identified in drugs seized by the drug enforcement administration. adb-fubinacalegal statuslegal status ca: schedule ii de: anlage ii (authorized trade only, not prescriptible) uk: class b us: schedule i identifiers iupac name n-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1h-indazole-3-carboxamide cas number1185282-00-1 ypubchem cid70969086chemspider29763706unii05235e1s2ocomptox dashboard (epa)dtxsid701009981 chemical and physical dataformulac21h23fn4o2molar mass382.439 g·mol−13d model (jsmol)interactive image smiles o=c(nc(c(n)=o)c(c)(c)c)c1=nn(cc2=cc=c(f)c=c2)c3=c1c=cc=c3 inchi inchi=inchi=1s/c21h23fn4o2/c1-21(2,3)18(19(23)27)24-20(28)17-15-6-4-5-7-16(15)26(25-17)12-13-8-10-14(22)11-9-13/h4-11,18h,12h2,1-3h3,(h2,23,27)(h,24,28)/t18-/m1/s1key:zssgcsinpvblqd-gosisdbhsa-n the (s)-enantiomer of adb-fubinaca is described in a 2009 pfizer patent and has been reported to be a potent agonist of the cb1 receptor and the cb2 receptor with ec50 values of 1.2 nm and 3.5 nm, respectively. adb-fubinaca features a carboxamide group at the 3-indazole position, like sdb-001 and sts-135. adb-fubinaca appears to be the product of rational drug design, since it differs from ab-fubinaca only by the replacement of the isopropyl group with a tert-butyl group. an analogue of adb-fubinaca, adsb-fub-187, containing a more functionalized carboxamide substituent was recently reported. side effects one death through coronary arterial thrombosis has been linked to adb-fubinaca intoxication. at least an additional 8 deaths in hungary in 2015 are linked to the usage of this material, all deaths were youngsters below 21. metabolism twenty-three adb-fubinaca major metabolites were identified in several incubations with cryopreserved human hepatocytes. major metabolic pathways were alkyl and indazole hydroxylation, terminal amide hydrolysis, subsequent glucuronide conjugations, and dehydrogenation. legality in the united states, adb-fubinaca is a schedule i controlled substance.