list of investigational sexual dysfunction drugs list of investigational sexual dysfunction drugs this is a list of investigational sexual dysfunction drugs, or drugs that are currently under development for clinical treatment of sexual dysfunction but are not yet approved. chemical/generic names are listed first, with developmental code names, synonyms, and brand names in parentheses. atrophic vaginitis estetrol (e4; donesta) – estrogen receptor agonist estetrol - mithra pharmaceuticals - adisinsight lasofoxifene (cp-336156, cp-336156-cb, fablyn, oporia) – selective estrogen receptor modulatorlasofoxifene - sermonix pharmaceuticals - adisinsight erectile dysfunction hcp-1302 – undefined mechanism of actionhcp 1302 - adisinsight nitroglycerin gel (eroxon, futura, med-2001–med-2005) – nitric oxide donornitroglycerin gel - futura medical - adisinsight tadalafil/tamsulosin (hcp-1303, ckd-397, ybh-1603)tadalafil/tamsulosin - hanmi pharmaceutical - adisinsighttadalafil/tamsulosin - ildong pharmaceutical - adisinsighttadalafil/tamsulosin - chong kun dang - adisinsighttadalafil/tamsulosin - yungjin pharmaceutical - adisinsight tt-701 (ly-2452473) – selective androgen receptor modulatoropk 88004 - adisinsight female anorgasmia testosterone low-dose intranasal (mpp-14, tbs-2, noseafix, tefina) – androgen receptor agonist testosterone intranasal (low-dose) - acerus pharmaceuticals - adisinsight female sexual dysfunction bp-101 – undefined mechanism of action bp 101 - ovoca bio - adisinsight bupropion/trazodone (s1p-104, s1p-205, lorexys, orexa) – norepinephrine reuptake inhibitor, nicotinic acetylcholine receptor antagonist, 5-ht2a receptor antagonist, α1-adrenergic receptor antagonist, weak serotonin reuptake inhibitorbupropion/trazodone - adisinsight buspirone/testosterone (lybridos) – 5-ht1a receptor partial agonist and androgen receptor agonist buspirone/testosterone - emotional brain - adisinsight lasofoxifene (cp-336156, cp-336156-cb, fablyn, oporia) – selective estrogen receptor modulator lasofoxifene - sermonix pharmaceuticals - adisinsight pl-6983 – selective mc4 receptor agonist research programme: sexual dysfunction therapy - palatin technologies - adisinsight sildenafil/testosterone (lybrido) – pde5 inhibitor and androgen receptor agonist sildenafil/testosterone - emotional brain - adisinsight tgfk09sd – 5-ht1a receptor agonist tgfk 09sd - adisinsight premature ejaculation clomipramine/sildenafil (cdfr-0812) – serotonin reuptake inhibitor and pde5 inhibitor clomipramine/sildenafil - ctc bio - adisinsight da-8031 – serotonin reuptake inhibitor da 8031 - adisinsight ix-01 – oxytocin receptor antagonist cligosiban - ixchelsis - adisinsight onabotulinumtoxina (botulinum toxin a, botox) – acetylcholine release inhibitoronabotulinum toxin a - abbvie - adisinsight unspecified vilazodone (viibryd, emd-68843, sb-659746a) – 5-ht1a receptor partial agonist and serotonin reuptake inhibitor vilazodone - abbvie - adisinsight