fluperlapine fluperlapine fluperlapine (nb 106-689), also known as fluoroperlapine, is a morphanthridine (11h-dibenzoazepine) atypical antipsychotic with additional antidepressant and sedative effects. it was first synthesized in 1979, and then subsequently studied in animals and humans in 1984 and beyond, but despite demonstrating efficacy in the treatment of a variety of medical conditions including schizophrenia, psychosis associated with parkinson's disease, depressive symptoms, and dystonia, it was never marketed. this was perhaps due to its capacity for producing potentially life-threatening agranulocytosis, similarly to clozapine, which it closely resembles both structurally and pharmacologically. fluperlapineclinical dataatc codenoneidentifiers iupac name 3-fluoro-6-(4-methylpiperazin-1-yl)-11h-dibenzoazepine cas number67121-76-0 npubchem cid49381chemspider44882 yuniiewg253m961chemblchembl63756 ycomptox dashboard (epa)dtxsid2046123 chemical and physical dataformulac19h20fn3molar mass309.388 g·mol−13d model (jsmol)interactive image smiles fc4ccc3c(/n=c(/n1ccn(c)cc1)c2ccccc2c3)c4 inchi inchi=1s/c19h20fn3/c1-22-8-10-23(11-9-22)19-17-5-3-2-4-14(17)12-15-6-7-16(20)13-18(15)21-19/h2-7,13h,8-12h2,1h3 ykey:obwgmkkhclhvie-uhfffaoysa-n y ny (what is this?) (verify) pharmacology binding profile receptorki (nm) 5-ht2a7.9 5-ht2c18.2 5-ht629 5-ht74.6 m18.8 m271 m341 m414 m517 d185 d2316.2 d3254.7 d421 synthesis patents: 3-fluoro-5,11-dihydro-6h-dibenzazepin-6-one (3)