para-chloromethamphetamine para-chloromethamphetamine para-chloromethamphetamine (also known as 4-chloromethamphetamine and 4-cma) is a stimulant that is the n-methyl derivative and prodrug of the neurotoxic drug para-chloroamphetamine (4-ca). it has been found to decrease serotonin in rats. further investigation into the long-term effects of chloroamphetamines discovered that administration of 4-cma caused a prolonged reduction in the levels of serotonin and the activity of tryptophan hydroxylase in the brain one month after injection of a single dose of the drug. para-chloromethamphetaminelegal statuslegal status de: npsg (industrial and scientific use only) uk: class b identifiers iupac name 1-(4-chlorophenyl)-n-methylpropan-2-amine cas number30572-91-9 ypubchem cid3128chemspider3016uniiixp5g5wmyacomptox dashboard (epa)dtxsid00897230 chemical and physical dataformulac10h14clnmolar mass183.68 g·mol−13d model (jsmol)interactive image smiles clc1=cc=c(c=c1)cc(c)nc inchi inchi=1s/c10h14cln/c1-8(12-2)7-9-3-5-10(11)6-4-9/h3-6,8,12h,7h2,1-2h3key:xxlwnlkeowwhdc-uhfffaoysa-n another study on rats found that 4-chloromethamphetamine was more potent at inducing conditioned taste aversion than methamphetamine. 4-chloromethamphetamine was further investigated in the 1960s along with 4-ca and it was noted that they differed from their parent amphetamine and methamphetamine substances by exhibiting only a slight central stimulant effect in both animals and humans and that they acted like antidepressants rather than stimulants. tablet containing 4-chloromethamphetamine, found in 2015 in belgium. 4-chloromethamphetamine was identified outside of the laboratory for the first time at the tomorrowland festival edition 2015, where a tablet was found in possession of a drug dealer (see picture).