chromosome 3 chromosome 3 chromosome 3 is one of the 23 pairs of chromosomes in humans. people normally have two copies of this chromosome. chromosome 3 spans 201 million base pairs (the building material of dna) and represents about 6.5 percent of the total dna in cells. chromosome 3human chromosome 3 pair after g-banding. one is from mother, one is from father.chromosome 3 pair in human male karyogram.featureslength (bp)201,105,948 bp(chm13)no. of genes1,024 (ccds)typeautosomecentromere positionmetacentric(90.9 mbp)complete gene listsccdsgene listhgncgene listuniprotgene listncbigene listexternal map viewersensemblchromosome 3entrezchromosome 3ncbichromosome 3ucscchromosome 3full dna sequencesrefseqnc_000003 (fasta) genbankcm000665 (fasta) genes number of genes the following are some of the gene count estimates of human chromosome 3. because researchers use different approaches to genome annotation their predictions of the number of genes on each chromosome varies (for technical details, see gene prediction). among various projects, the collaborative consensus coding sequence project (ccds) takes an extremely conservative strategy. so ccds's gene number prediction represents a lower bound on the total number of human protein-coding genes. estimated by protein-coding genes non-coding rna genes pseudogenes source release date ccds1,024—— 2016-09-08 hgnc1,036483761 2017-05-12 ensembl1,0731,158761 2017-03-29 uniprot1,081—— 2018-02-28 ncbi1,0851,108902 2017-05-19 list of genes the following is a partial list of genes on human chromosome 3. for complete list, see the link in the infobox on the right. p-arm partial list of the genes located on p-arm (short arm) of human chromosome 3: alas1: aminolevulinate, delta-, synthase 1 apeh: encoding enzyme acylamino-acid-releasing enzyme arpp-21: cyclic amp-regulated phosphoprotein, 21 kda azi2: encoding protein 5-azacytidine-induced protein 2 brk1: scar/wave actin nucleating complex subunit brpf1: bromodomain and phd finger containing 1 btd: biotinidase c3orf14-chromosome 3 open reading frame 14: predicted dna binding protein. cfap20dc: encoding protein chromosome 3 open reading frame 67 c3orf62: chromosome 3 open reading frame 62 cacna2d3: calcium channel, voltage-dependent, alpha 2/delta subunit 3 ccr5: chemokine (c-c motif) receptor 5 cggbp1: cgg triplet repeat binding protein 1 cmtm7: cklf like marvel transmembrane domain containing 7 cntn4: contactin 4 col7a1: collagen, type vii, alpha 1 (epidermolysis bullosa, dystrophic, dominant and recessive) crbn: cereblon protein dclk3: doublecortin like kinase 3 dlec1: encoding protein deleted in lung and esophageal cancer 1 eaf1: ell associated factor 1 entpd3: ectonucleoside triphosphate diphosphohydrolase 3 fam107a: family with sequence similarity 107 member a fam19a1: family with sequence similarity 19 member a1, c-c motif chemokine like fbxl2: f-box and leucine rich repeat protein 2 foxp1: forkhead box protein p1 fra3a encoding protein fragile site, aphidicolin type, common, fra(3)(p24.2) frmd4b encoding protein ferm domain containing 4b ghrlos: non-coding rna ghrelin opposite strand (non-protein coding) gmppb: gdp-mannose pyrophosphorylase b hacl1: encoding protein 2-hydroxyacyl-coa lyase 1 hemk1: encoding protein hemk methyltransferase family member 1 higd1a: hig1 domain family member 1a htd2: encoding protein hydroxyacyl-thioester dehydratase type 2 lars2: leucyl-trna synthetase, mitochondrial limd1: lim domain-containing protein 1 loc105377021: encoding protein loc105377021 linc00312: long intergenic non-protein-coding rna 312 lztfl1: leucine zipper transcription factor like 1 mir138-1: encoding protein microrna 138-1 mir885: encoding protein microrna 885 mitf: microphthalmia-associated transcription factor mlh1: mutl homolog 1, colon cancer, nonpolyposis type 2 (e. coli) myrip: myosin viia and rab interacting protein nbeal2: neurobeachin-like 2 ndufaf3: encoding enzyme nadh dehydrogenase 1 alpha subcomplex assembly factor 3 nktr: nk-tumor recognition protein nprl2: nitrogen permease regulator 2-like protein oxtr: oxytocin receptor pcaf: acetyltransferase activity phf7 encoding protein phd finger protein 7 prickle2: encoding protein prickle planar cell polarity protein 2 pthr1: parathyroid hormone receptor 1 qrich1: encoding protein qrich1, also known as glutamine-rich protein 1, rbm6: rna-binding protein 6 rpp14: ribonuclease p protein subunit p14 scn5a: sodium channel, voltage-gated, type v, alpha (long qt syndrome 3) setd5: set domain containing 5 sfmbt1: scm-like with four mbt domains 1 slc25a20: solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 stt3b: catalytic subunit of the oligosaccharyltransferase complex synpr: synaptoporin tafa4: encoding protein family with sequence similarity 19 member a4, c-c motif chemokine like tcaim: encoding protein t-cell activation inhibitor, mitochondrial tdgf1: teratocarcinoma-derived growth factor 1 tmem158: transmembrane protein 158 tmie: transmembrane inner ear trak1: trafficking kinesin-binding protein 1 trank1: encoding protein tetratricopeptide repeat and ankyrin repeat containing 1 ttll3: encoding protein tubulin tyrosine ligase-like family, member 3 tusc2: tumor suppressor candidate 2 ucn2: urocortin-2 ulk4: unc-51 like kinase 4 vgll3: vestigial-like family member 3 vhl: von hippel-lindau tumor suppressor zmynd10: zinc finger mynd-type containing 10 znf197: encoding protein zinc finger protein 197 znf502: encoding protein zinc finger protein 502 znf620: encoding protein zinc finger protein 620 znf621: encoding protein zinc finger protein 621 znf717: encoding protein zinc finger protein 717 q-arm partial list of the genes located on q-arm (long arm) of human chromosome 3: adipoq: adiponectin amotl2: encoding protein angiomotin-like protein 2 arhgap31: rho grpase activating protein 31 timmdc1: timmdc1 c3orf70 chromosome 3 open reading frame 70 campd1: camptodactyly ccdc80: coiled-coil domain containing protein 80 cd200r1: cell surface glycoprotein cd200 receptor 1 chst13: encoding protein carbohydrate (chondroitin 4) sulfotransferase 13 cldnd1: claudin domain containing 1 cpn2: carboxypeptidase n subunit 2 cpox: coproporphyrinogen oxidase (coproporphyria, harderoporphyria) dppa2: developmental pluripotency associated 2 dtx3l: encoding protein deltex e3 ubiquitin ligase 3l dzip3: encoding protein daz interacting zinc finger protein 3 eaf2: ell associated factor 2 efcc1: ef-hand and coiled-coil domain containing 1 etm1: essential tremor 1 etv5: ets variant 5 fam3d: family with sequence similarity 3, member d fam43a: family with sequence similarity 43 member a fam162a: family with sequence similarity 162 member a fbxo40: encoding protein f-box protein 40 filip1l: encoding protein filamin a interacting protein 1 like gyg1: glycogenin-1 hacd2 encoding protein 3-hydroxyacyl-coa dehydratase 2 hgd: homogentisate 1,2-dioxygenase (homogentisate oxidase) ift122: intraflagellar transport gene 122 kiaa1257: kiaa1257 linc01279: encoding protein long intergenic non-protein coding rna 1279 lncr5: encoding protein lung cancer susceptibility 5 lmln: encoding protein leishmanolysin-like (metallopeptidase m8 family) lrrc15: leucine rich repeat containing 15 lsg1: large subunit gtpase 1 homolog mb21d2: encoding protein mab-21 domain containing 2 mccc1: methylcrotonoyl-coenzyme a carboxylase 1 (alpha) morc1: encoding protein morc family cw-type zinc finger 1 mylk: telokin nepro: encoding protein nucleolus and neural progenitor protein nfkbiz: nf-kappa-b inhibitor zeta otol1: encoding glycoprotein otolin parp14 encoding protein poly(adp-ribose) polymerase family member 14 pccb: propionyl coenzyme a carboxylase, beta polypeptide pdcd10: programmed cell death 10 pik3ca: phosphoinositide-3-kinase, catalytic, alpha polypeptide pisrt1: long non-coding rna proser1: proline and serine rich protein 1 rab7: rab7, member ras oncogene family rasa2: encoding protein ras p21 protein activator 2 retnlb: resistin-like beta rho: rhodopsin visual pigment riox2: ribosomal oxygenase 2 selt: selenoprotein t senp7: sentrin-specific protease 7 serp1: stress-associated endoplasmic reticulum protein 1 sox2: transcription factor sox2ot: sox2 overlapping transcript spg14 encoding protein spastic paraplegia 14 (autosomal recessive) srprb: signal recognition particle receptor subunit beta tex55: encoding protein testis expressed 55 tmem44: encoding protein transmembrane protein 44 tm4sf1: transmembrane 4 l6 family member 1 tmprss7: encoding protein transmembrane serine protease 7 tp63: tumor protein p63 trat1: t-cell receptor-associated transmembrane adapter 1 ush3a: usher syndrome 3a zbed2: encoding protein zinc finger bed-type containing 2 znf9: zinc finger protein 9 (a cellular retroviral nucleic acid binding protein) diseases and disorders the following diseases and disorders are some of those related to genes on chromosome 3: 3-methylcrotonyl-coa carboxylase deficiency 3q29 microdeletion syndrome acute myeloid leukemia (aml) alkaptonuria arrhythmogenic right ventricular dysplasia atransferrinemia autism autosomal dominant optic atrophy adoa plus syndrome biotinidase deficiency blepharophimosis, epicanthus inversus and ptosis type 1 breast/colon/lung/pancreatic cancer brugada syndrome castillo fever carnitine-acylcarnitine translocase deficiency cataracts cerebral cavernous malformation charcot–marie–tooth disease, type 2 charcot–marie–tooth disease chromosome 3q duplication syndrome coproporphyria a location on human chromosome 3 is associated with respiratory failure and possibly with increased severity in covid-19 dandy–walker syndrome deafness diabetes dystrophic epidermolysis bullosa endplate acetylcholinesterase deficiency essential tremors ectrodactyly, case 4 glaucoma, primary open angle glycogen storage disease hailey–hailey disease harderoporphyrinuria heart block, progressive/nonprogressive hereditary coproporphyria hereditary nonpolyposis colorectal cancer hiv infection, susceptibility/resistance to hypobetalipoproteinemia, familial hypothermia leukoencephalopathy with vanishing white matter long qt syndrome lymphomas malignant hyperthermia susceptibility metaphyseal chondrodysplasia, murk jansen type microcoria möbius syndrome moyamoya disease mucopolysaccharidosis muir–torre family cancer syndrome myotonic dystrophy neuropathy, hereditary motor and sensory, okinawa type night blindness nonsyndromic deafness ovarian cancer porphyria propionic acidemia protein s deficiency pseudo-zellweger syndrome retinitis pigmentosa romano–ward syndrome seckel syndrome sensenbrenner syndrome septo-optic dysplasia short stature spinocerebellar ataxia sucrose intolerance t-cell leukemia translocation altered gene usher syndrome von hippel–lindau syndrome waardenburg syndrome xeroderma pigmentosum, complementation group c cytogenetic band g-banding ideograms of human chromosome 3g-banding ideogram of human chromosome 3 in resolution 850 bphs. band length in this diagram is proportional to base-pair length. this type of ideogram is generally used in genome browsers (e.g. ensembl, ucsc genome browser).g-banding patterns of human chromosome 3 in three different resolutions (400, 550 and 850). band length in this diagram is based on the ideograms from iscn (2013). this type of ideogram represents actual relative band length observed under a microscope at the different moments during the mitotic process. g-bands of human chromosome 3 in resolution 850 bphs chr. arm band iscnstart iscnstop basepairstart basepairstop stain density 3p 26.3017512,800,000 gpos50 3p 26.21752632,800,0014,000,000 gneg 3p 26.12634084,000,0018,100,000 gpos50 3p 25.34086428,100,00111,600,000 gneg 3p 25.264275911,600,00113,200,000 gpos25 3p 25.175996313,200,00116,300,000 gneg 3p 24.3963126916,300,00123,800,000 gpos100 3p 24.21269135723,800,00126,300,000 gneg 3p 24.11357156126,300,00130,800,000 gpos75 3p 231561175130,800,00132,000,000 gneg 3p 22.31751192632,000,00136,400,000 gpos50 3p 22.21926201336,400,00139,300,000 gneg 3p 22.12013218839,300,00143,600,000 gpos75 3p 21.332188245143,600,00144,100,000 gneg 3p 21.322451262644,100,00144,200,000 gpos50 3p 21.312626323944,200,00150,600,000 gneg 3p 21.23239338550,600,00152,300,000 gpos25 3p 21.13385367652,300,00154,400,000 gneg 3p 14.33676391054,400,00158,600,000 gpos50 3p 14.23910414358,600,00163,800,000 gneg 3p 14.14143436263,800,00169,700,000 gpos50 3p 134362456669,700,00174,100,000 gneg 3p 12.34566481474,100,00179,800,000 gpos75 3p 12.24814494679,800,00183,500,000 gneg 3p 12.14946507783,500,00187,100,000 gpos75 3p 11.25077513587,100,00187,800,000 gneg 3p 11.15135526687,800,00190,900,000 acen 3q 11.15266542790,900,00194,000,000 acen 3q 11.25427560294,000,00198,600,000 gvar 3q 12.15602576298,600,001100,300,000 gneg 3q 12.257625850100,300,001101,200,000 gpos25 3q 12.358505996101,200,001103,100,000 gneg 3q 13.1159966229103,100,001106,500,000 gpos75 3q 13.1262296361106,500,001108,200,000 gneg 3q 13.1363616594108,200,001111,600,000 gpos50 3q 13.265946682111,600,001113,700,000 gneg 3q 13.3166826871113,700,001117,600,000 gpos75 3q 13.3268716973117,600,001119,300,000 gneg 3q 13.3369737148119,300,001122,200,000 gpos75 3q 21.171487294122,200,001124,100,000 gneg 3q 21.272947440124,100,001126,100,000 gpos25 3q 21.374407674126,100,001129,500,000 gneg 3q 22.176747936129,500,001134,000,000 gpos25 3q 22.279368053134,000,001136,000,000 gneg 3q 22.380538228136,000,001139,000,000 gpos25 3q 2382288461139,000,001143,100,000 gneg 3q 2484618811143,100,001149,200,000 gpos100 3q 25.188119001149,200,001152,300,000 gneg 3q 25.290019162152,300,001155,300,000 gpos50 3q 25.3191629264155,300,001157,300,000 gneg 3q 25.3292649366157,300,001159,300,000 gpos50 3q 25.3393669453159,300,001161,000,000 gneg 3q 26.194539803161,000,001167,900,000 gpos100 3q 26.298039949167,900,001171,200,000 gneg 3q 26.31994910183171,200,001176,000,000 gpos75 3q 26.321018310329176,000,001179,300,000 gneg 3q 26.331032910489179,300,001183,000,000 gpos75 3q 27.11048910620183,000,001184,800,000 gneg 3q 27.21062010737184,800,001186,300,000 gpos25 3q 27.31073710883186,300,001188,200,000 gneg 3q 281088311175188,200,001192,600,000 gpos75 3q 291117511700192,600,001198,295,559 gneg