dibenzepin dibenzepin dibenzepin, sold under the brand name noveril among others, is a tricyclic antidepressant (tca) used widely throughout europe for the treatment of depression. it has similar efficacy and effects relative to other tcas like imipramine but with fewer side effects. dibenzepinclinical datatrade namesnoveril, anslopax, deprex, ecatril, neodit, victorilahfs/drugs.cominternational drug namesroutes ofadministrationoralatc coden06aa08 (who) legal statuslegal status in general: ℞ (prescription only) pharmacokinetic databioavailability25%protein binding80%metabolismhepaticelimination half-life5 hoursexcretionurine (80%), feces (20%)identifiers iupac name 10-(2-(dimethylamino)ethyl)-5-methyl-5h-dibenzodiazepin-11(10h)-one cas number4498-32-2 ypubchem cid9419chemspider9048 yunii510sjz1y6lkeggd07812 ychemblchembl1442422 ncomptox dashboard (epa)dtxsid7022916 chemical and physical dataformulac18h21n3omolar mass295.386 g·mol−13d model (jsmol)interactive image smiles o=c2c1c(cccc1)n(c3c(n2ccn(c)c)cccc3)c inchi inchi=1s/c18h21n3o/c1-19(2)12-13-21-17-11-7-6-10-16(17)20(3)15-9-5-4-8-14(15)18(21)22/h4-11h,12-13h2,1-3h3 ykey:qpggekprgvjkqb-uhfffaoysa-n y ny (what is this?) (verify) medical uses dibenzepin is used mainly in the treatment of major depressive disorder. like other tcas, dibenzepin may have potential use in the treatment of chronic neuropathic pain. overdose main article: tricyclic antidepressant overdose as tcas have a relatively narrow therapeutic index, the likelihood of overdose (both accidental and intentional) is fairly high and should be considered carefully by the prescribing physician prior to patient use. symptoms of overdose are similar to those of other tcas, with cardiac toxicity (due to inhibition of sodium and calcium channels) generally occurring before the threshold for serotonin syndrome is reached. due to this risk, tcas are rarely selected as the first-line treatment for depression. pharmacology pharmacodynamics