voxtalisib voxtalisib voxtalisib (xl-765, sar245409) is a drug which acts as a dual inhibitor of the kinase enzymes phosphatidylinositol 3-kinase (pi3k) and mechanistic target of rapamycin (mtor). it is in clinical trials for the treatment of various types of cancer. voxtalisibidentifiers iupac name 2-amino-8-ethyl-4-methyl-6-(1h-pyrazol-5-yl)pyridopyrimidin-7-one cas number934493-76-2pubchem cid16123056drugbankdb12400chemspider17279963uniicvl1685gphchebichebi:124914chemblchembl3545366chemical and physical dataformulac13h14n6omolar mass270.296 g·mol−13d model (jsmol)interactive image smiles ccn1c2=nc(=nc(=c2c=c(c1=o)c3=cc=nn3)c)n inchi inchi=1s/c13h14n6o/c1-3-19-11-8(7(2)16-13(14)17-11)6-9(12(19)20)10-4-5-15-18-10/h4-6h,3h2,1-2h3,(h,15,18)(h2,14,16,17)key:rghydlzmtydbdt-uhfffaoysa-n