galli–galli disease galli–galli disease galli–galli disease is a rare inherited condition that has close resemblance clinically to dowling-degos' disease, but is histologically distinct, characterized by skin lesions that are 1- to 2-mm slightly keratotic red to dark brown papules which are focally confluent in a reticulate pattern.: 856 the disease is also characterized by slowly progressive and disfiguring reticulate hyperpigmentation of the flexures, clinically and histopathologically diagnostic for dowling-degos disease but also associated with suprabasal, nondyskeratotic acantholysis. galli–galli diseasespecialtydermatology