butaperazine butaperazine butaperazine (repoise, tyrylen) is a typical antipsychotic of the phenothiazine class. it was approved in 1967, and possibly discontinued in the 1980s. butaperazineclinical dataatc coden05ab09 (who) identifiers iupac name 1-phenothiazin-2-yl]butan-1-one cas number653-03-2 ypubchem cid12598drugbankdb13213chemspider12078 yuniitxp4t9106skeggd02642chebichebi:135663chemblchembl1697826comptox dashboard (epa)dtxsid1022712 echa infocard100.010.450 chemical and physical dataformulac24h31n3osmolar mass409.59 g·mol−13d model (jsmol)interactive image smiles o=c(c2cc1n(c3c(sc1cc2)cccc3)cccn4ccn(c)cc4)ccc inchi inchi=1s/c24h31n3os/c1-3-7-22(28)19-10-11-24-21(18-19)27(20-8-4-5-9-23(20)29-24)13-6-12-26-16-14-25(2)15-17-26/h4-5,8-11,18h,3,6-7,12-17h2,1-2h3 ykey:dvlbytmysmakhp-uhfffaoysa-n y (verify) synthesis patent: 2-butyrylphenothiazine (1) is the requisite starting material for carrying out the procedure. it is prepared in a manner that is synonymous with the method used in the propiomazine and propiopromazine already discussed. the 1-(γ-chloropropyl)-4-methylpiperazine (2) is prepared in the conventional way from alkylating 1-methylpiperazine and 1-bromo-3-chloropropane. sodamide is used to extract the 10-h thereby facilitating the nucleophilic substitution reaction. and completing the instalment of the sidechain.