uterine hypoplasia uterine hypoplasia uterine hypoplasia, also known as naive uterus or infantile uterus, is a reproductive disorder characterized by hypoplasia of the uterus. it is usually due to pubertal failure/hypogonadism and may be treated with puberty induction using estrogens and/or progestogens. uterine hypoplasiaother namesnaive uterus or infantile uterusspecialtyreproductive endocrinologist