20α-dihydrotrengestone 20α-dihydrotrengestone 20α-dihydrotrengestone (20α-dhtg), also known as 20α-hydroxytrengestone, as well as 6-chloro-20(s)-hydroxy-9β,10α-pregna-1,4,6-trien-3-one, is a progestin and the major active metabolite of trengestone. it appears that trengestone is a prodrug of 20α-dhtg, as it is largely transformed into this metabolite when given orally in humans. 20α-dhtg has potent progestogenic activity similarly to trengestone. 20α-dihydrotrengestoneclinical dataother names20α-dhtg; 20α-hydroxytrengestone; 6-chloro-20(s)-hydroxy-9β,10α-pregna-1,4,6-trien-3-onedrug classprogestin; progestogenpharmacokinetic dataelimination half-life8–14 hourschemical and physical dataformulac21h26clo2molar mass345.89 g·mol−13d model (jsmol)interactive image smiles o()(c)()1cc()2()3c=c(cl)c4=cc(c=c4(c)3()cc21c)=o inchi inchi=1s/c21h26clo2/c1-12(23)15-4-5-16-14-11-19(22)18-10-13(24)6-8-21(18,3)17(14)7-9-20(15,16)2/h6,8,10-11,14-17,23h,4-5,7,9h2,1-3h3/t14-,15+,16-,17+,20+,21-/m0/s1key:yokuotgyggeomr-oayggaorsa-n