adafenoxate adafenoxate adafenoxate is a compound related to centrophenoxine, that has been found to act as a nootropic in rats. adafenoxate names preferred iupac name 2-ethyl (4-chlorophenoxy)acetate identifiers cas number 82168-26-1 n 3d model (jsmol) interactive image chembl chembl2104053 n chemspider 58080 y pubchem cid 64517 unii b8vqu4c05j y comptox dashboard (epa) dtxsid4046280 inchi inchi=1s/c20h26clno3/c21-17-1-3-18(4-2-17)25-13-19(23)24-6-5-22-20-10-14-7-15(11-20)9-16(8-14)12-20/h1-4,14-16,22h,5-13h2 ykey: plsmxiqmwyshiv-uhfffaoysa-n yinchi=1/c20h26clno3/c21-17-1-3-18(4-2-17)25-13-19(23)24-6-5-22-20-10-14-7-15(11-20)9-16(8-14)12-20/h1-4,14-16,22h,5-13h2key: plsmxiqmwyshiv-uhfffaoyak smiles clc4ccc(cc4)occ(=o)occnc12cc3cc(c1)cc(c2)c3 properties chemical formula c20h26clno3 molar mass 363.87834 g/mol except where otherwise noted, data are given for materials in their standard state (at 25 °c , 100 kpa). n verify (what is yn ?) infobox references synthesis patent: ex 1: 4-chlorophenoxyacetic acid (pcpa) is converted to its acid chloride to give 4-chlorophenoxyacetyl chloride (1). esterification with 2-(1-adamantylamino)ethanol (2) gives adafenoxate (3) in a single step. ex 2: same as above but fischer–speier esterification done via a ds-trap. this gives an 88% yield.