sebacic acid sebacic acid sebacic acid is a naturally occurring dicarboxylic acid with the chemical formula (ch2)8(co2h)2. it is a white flake or powdered solid. sebaceus is latin for tallow candle, sebum is latin for tallow, and refers to its use in the manufacture of candles. sebacic acid is a derivative of castor oil. sebacic acid names preferred iupac name decanedioic acid other names 1,8-octanedicarboxylic aciddecane-1,10-dioic acid identifiers cas number 111-20-6 y 3d model (jsmol) interactive image chebi chebi:41865 y chemspider 5004 y echa infocard 100.003.496 ec number 203-845-5 mesh c011107 pubchem cid 5192 unii 97an39ictc y comptox dashboard (epa) dtxsid7026867 inchi inchi=1s/c10h18o4/c11-9(12)7-5-3-1-2-4-6-8-10(13)14/h1-8h2,(h,11,12)(h,13,14) nkey: cxmxrphrnrromy-uhfffaoysa-n ninchi=1/c10h18o4/c11-9(12)7-5-3-1-2-4-6-8-10(13)14/h1-8h2,(h,11,12)(h,13,14)key: cxmxrphrnrromy-uhfffaoyae smiles oc(=o)ccccccccc(=o)o properties chemical formula c10h18o4 molar mass 202.250 g·mol−1 density 1.209 g/cm3 melting point 131 to 134.5 °c (267.8 to 274.1 °f; 404.1 to 407.6 k) boiling point 294.4 °c (561.9 °f; 567.5 k) at 100 mmhg solubility in water 0.25 g/l acidity (pka) 4.720, 5.450 except where otherwise noted, data are given for materials in their standard state (at 25 °c , 100 kpa). n verify (what is yn ?) infobox references in the industrial setting, sebacic acid and its homologues such as azelaic acid can be used as a monomer for nylon 610, plasticizers, lubricants, hydraulic fluids, cosmetics, candles, etc. production sebacic acid is produced from castor oil by cleavage of ricinoleic acid, which is obtained from castor oil. octanol & glycerin is a byproduct. it can also be obtained from decalin via the tertiary hydroperoxide, which gives cyclodecenone, a precursor to sebacic acid. potential medical significance sebum is a secretion by skin sebaceous glands. it is a waxy set of lipids composed of triglycerides (≈41%), wax esters (≈26%), squalene (≈12%), and free fatty acids (≈16%). included in the free fatty acid secretions in sebum are polyunsaturated fatty acids of which sebacic acid is a major component. sebacic acid is also found in other lipids that coat the skin surface. human neutrophils can convert sebacic acid to its 5-oxo analog, i.e., 5-oxo-6e,8z-octadecenoic acid, a structural analog of 5-oxo-eicosatetraenoic acid and like this oxo-eicosatetraenoic acid is an exceptionally potent activator of eosinophils, monocytes, and other pro-inflammatory cells from humans and other species. this action is mediated by the oxer1 receptor on these cells. it is suggested that sebacic acid is converted to its 5-oxo analog during, and thereby stimulates pro-inflammatory cells to contribute to the worsening of, various inflammatory skin conditions.