to whether the glands were indeed suprarenal or part of the kidney. one of the most recognized works on the adrenal glands came in 1855 with the publication of on the constitutional and local effects of disease of the suprarenal capsule, by the english physician thomas addison. in his monography, addison described what the french physician george trousseau would later name addison's disease, an eponym still used today for a condition of adrenal insufficiency and its related clinical manifestations. in 1894, english physiologists george oliver and edward schafer studied the action of adrenal extracts and observed their pressor effects. in the following decades several physicians experimented with extracts from the adrenal cortex to treat addison's disease. edward calvin kendall, philip hench and tadeusz reichstein were then awarded the 1950 nobel prize in physiology or medicine for their discoveries on the structure and effects of the adrenal hormones.