tetrahydrocannabiphorol tetrahydrocannabiphorol tetrahydrocannabiphorol (thcp) is a potent phytocannabinoid, a cb1 and cb2 agonist which was known as a synthetic homologue of thc, but for the first time in 2019 was isolated as a natural product in trace amounts from cannabis sativa. it is structurally similar to δ9-thc, the main active component of cannabis, but with the pentyl side chain extended to heptyl. since it has a longer side chain, its cannabinoid effects are "far higher than δ9-thc itself." tetrahydrocannabiphorol has a reported binding affinity approximately 33 times that of delta-9-thc.