trimebutine trimebutine trimebutine is a drug with antimuscarinic and weak mu opioid agonist effects. it is used for the treatment of irritable bowel syndrome and other gastrointestinal disorders. trimebutineclinical datatrade namesdebridat, recutin, polybutin, othersahfs/drugs.cominternational drug namesatc codea03aa05 (who) identifiers iupac name 2-(dimethylamino)-2-phenylbutyl 3,4,5-trimethoxybenzoate cas number39133-31-8 ypubchem cid5573chemspider5372 nuniiqz1oj92e5rchemblchembl190044 ncomptox dashboard (epa)dtxsid4023707 echa infocard100.049.354 chemical and physical dataformulac22h29no5molar mass387.476 g·mol−13d model (jsmol)interactive image smiles ccc(coc(=o)c1=cc(=c(c(=c1)oc)oc)oc)(c2=cc=cc=c2)n(c)c inchi inchi=1s/c22h29no5/c1-7-22(23(2)3,17-11-9-8-10-12-17)15-28-21(24)16-13-18(25-4)20(27-6)19(14-16)26-5/h8-14h,7,15h2,1-6h3 nkey:lordfxwuhhsaqu-uhfffaoysa-n n ny (what is this?) (verify) the major product from drug metabolism of trimebutine in human beings is nortrimebutine, which comes from removal of one of the methyl groups attached to the nitrogen atom. trimebutine exerts its effects in part due to causing a premature activation of phase iii of the migrating motor complex in the digestive tract. both trimebutine and its metabolite are commercially available. brand names the maleic acid salt of trimebutine is marketed under the trademarks of antinime, cineprac, colospasmyl, colypan, crolipsa, debricol, debridat, digedrat, espabion, gast reg, irritratil, krisxon, muttifen, neotina, polybutin, sangalina, trebutel, tribudat, tributina, trim, trimeb, trimedat, and trimedine.