mri artifact mri artifact an mri artifact is a visual artifact (an anomaly seen during visual representation) in magnetic resonance imaging (mri). it is a feature appearing in an image that is not present in the original object. many different artifacts can occur during mri, some affecting the diagnostic quality, while others may be confused with pathology. artifacts can be classified as patient-related, signal processing-dependent and hardware (machine)-related. patient-related mr artifacts motion artifacts fig. 1. motion artifact (t1 coronal study of cervical vertebrae). a motion artifact is one of the most common artifacts in mr imaging. motion can cause either ghost images or diffuse image noise in the phase-encoding direction. the reason for mainly affecting data sampling in the phase-encoding direction is the significant difference in the time of acquisition in the frequency- and phase-encoding directions. frequency-encoding sampling in all the rows of the matrix (128, 256 or 512) takes place during a single echo (milliseconds). phase-encoded sampling takes several seconds, or even minutes, owing to the collection of all the k-space lines to enable fourier analysis. major physiological movements are of millisecond to seconds duration and thus too slow to affect frequency-encoded sampling, but they have a pronounced effect in the phase-encoding direction. periodic movements such as cardiac movement and blood vessel or csf pulsation cause ghost images, while non-periodic movement causes diffuse image noise (fig. 1). ghost image intensity increases with amplitude of movement and the signal intensity from the moving tissue. several methods can be used to reduce motion artifacts, including patient immobilisation, cardiac and respiratory gating, signal suppression of the tissue causing the artifact, choosing the shorter dimension of the matrix as the phase-encoding direction, view-ordering or phase-reordering methods and swapping phase and frequency-encoding directions to move the artifact out of the field of interest. flow fig. 2. flow-related signal loss in the carotid and basillary arteries (t2 axial study of the brain). flow can manifest as either an altered intravascular signal (flow enhancement or flow-related signal loss), or as flow-related artifacts (ghost images or spatial misregistration). flow enhancement, also known as inflow effect, is caused by fully magnetised protons entering the imaged slice while the stationary protons have not fully regained their magnetization. the fully magnetized protons yield a high signal in comparison with the rest of the surroundings. high velocity flow causes the protons entering the image to be removed from it by the time the 180-degree pulse is administered. the effect is that these protons do not contribute to the echo and are registered as a signal void or flow-related signal loss (fig. 2). spatial misregistration manifests as displacement of an intravascular signal owing to position encoding of a voxel in the phase direction preceding frequency encoding by time te/2.the intensity of the artifact is dependent on the signal intensity from the vessel, and is less apparent with increased te. metal artifacts fig. 3. metal-related artifacts. fig. 4. metal-related artifacts. metal artifacts occur at interfaces of tissues with different magnetic susceptibilities, which cause local magnetic fields to distort the external magnetic field. this distortion changes the precession frequency in the tissue leading to spatial mismapping of information. the degree of distortion depends on the type of metal (stainless steel having a greater distorting effect than titanium alloy), the type of interface (most striking effect at soft tissue-metal interfaces), pulse sequence and imaging parameters. metal artifacts are caused by external ferromagnetics such as cobalt containing make-up, internal ferromagnetics such as surgical clips, spinal hardware and other orthopaedic devices, and in some cases, metallic objects swallowed by people with pica. manifestation of these artifacts is variable, including total signal loss, peripheral high signal and image distortion (figs 3 and 4). reduction of these artifacts can be attempted by orientating the long axis of an implant or device parallel to the long axis of the external magnetic field, possible with mobile extremity imaging and an open magnet. further methods used are choosing the appropriate frequency encoding direction, since metal artifacts are most pronounced in this direction, using smaller voxel sizes, fast imaging sequences, increased readout bandwidth and avoiding gradient-echo imaging when metal is present. a technique called mars (metal artifact reduction sequence) applies an additional gradient, along the slice select gradient at the time the frequency encoding gradient is applied. the ways in which the data are sampled, processed and mapped out on the image matrix manifest these artifacts. chemical shift artifact fig. 5. chemical shift artifact: bright and dark streaks around the kidneys in an axial gradientecho opposed-phase image. chemical shift artifact occurs at the fat/water interface in the frequency encoding direction (fig. 5). these artifacts arise due to the difference in resonance of protons as a result of their micromagnetic environment. the protons of fat resonate at a slightly lower frequency than those of water. high field strength magnets are particularly susceptible to this artifact. determination of the artifact can be made by swapping the phase- and frequency-encoding gradients and examining the resultant shift of fat tissue. partial volume main article: partial volume (imaging) partial volume artifacts arise from the size of the voxel over which the signal is averaged. objects smaller than the voxel dimensions lose their identity, and loss of detail and spatial resolution occurs. reduction of these artifacts is accomplished by using a smaller pixel size and/or a smaller slice thickness. wrap-around fig. 6. wrap-around artifacts. fig. 7. wrap-around artifacts. a wrap-around artifact also known as an aliasing artifact, is a result of mismapping of anatomy that lies outside the field of view but within the slice volume. the selected field of view is smaller than the size of the imaged object. the anatomy is usually displaced to the opposite side of the image (figs 6 and 7). it can be caused by non-linear gradients or by undersampling of the frequencies contained within the return signal. the sampling rate must be twice the maximal frequency that occurs in the object (nyquist sampling limit). if not, the fourier transform will assign very low values to the frequency signals greater than the nyquist limit. these frequencies will then ‘wrap around’ to the opposite side of the image, masquerading as low-frequency signals. in the frequency encode direction a filter can be applied to the acquired signal to eliminate frequencies greater than the nyquist frequency. in the phase encode direction, artifacts can be reduced by an increasing number of phase encode steps (increased image time). for correction, a larger field of view may be chosen. gibbs artifacts fig. 8. gibbs artifact (t1 sagittal study of the brain). gibbs artifacts or gibbs ringing artifacts, also known as truncation artifacts are caused by the under-sampling of high spatial frequencies at sharp boundaries in the image. lack of appropriate high-frequency components leads to an oscillation at a sharp transition known as a ringing artifact. it appears as multiple, regularly spaced parallel bands of alternating bright and dark signal that slowly fade with distance (fig. 8). ringing artifacts are more prominent in smaller digital matrix sizes. methods employed to correct gibbs artifact include filtering the k-space data prior to fourier transform, increasing the matrix size for a given field of view, the gegenbauer reconstruction and bayesian approach. this is a wide and still expanding subject. only a few common artifacts are recognised. radiofrequency (rf) quadrature rf detection circuit failure arises from improper detector channel operation. fourier-transformed data display a bright spot in the centre of the image. if one channel of the detector has a higher gain than the other it will result in object ghosting in the image. this is the result of a hardware failure and must be addressed by a service representative. external magnetic field (b0) inhomogeneity fig. 9. b0 inhomogeneity: intensity distortion across a t1 axial study of the lumbar vertebrae. b0 inhomogeneity leads to mismapping of tissues. inhomogeneous external magnetic field causes either spatial, intensity, or both distortions. intensity distortion occurs when the field in a location is greater or less than in the rest of the imaged object (fig. 9). spatial distortion results from long-range field gradients, which remain constant in the inhomogeneous field. gradient field artifacts magnetic field gradients are used to spatially encode the location of signals from excited protons within the volume being imaged. the slice select gradient defines the volume (slice). phase- and frequency-encoding gradients provide the information in the other two dimensions. any deviation in the gradient would be represented as a distortion. as the distance increases from the centre of the applied gradient, loss of field strength occurs at the periphery. anatomical compression occurs and is especially pronounced on coronal and sagittal imaging. when the phase-encoding gradient is different, the width or height of the voxel is different, resulting in distortion. anatomical proportions are compressed along one or the other axis. square pixels (and voxels) should be obtained. ideally the phase gradient should be assigned to the smaller dimension of the object and the frequency gradient to the larger dimension. in practice this is not always possible because of the necessity of displacing motion artifacts. this may be corrected by reducing the field of view, by lowering the gradient field strength or by decreasing the frequency bandwidth of radio signal. if correction is not achieved, the cause might be either a damaged gradient coil or an abnormal current passing through the gradient coil. rf (b1) inhomogeneity variation in intensity across the image may be due to the failure of the rf coil, non-uniform b1 field, non-uniform sensitivity of the receive only coil (spaces between wire in the coil, uneven distribution of wire), or presence of non-ferromagnetic material in the imaged object. when using a flash sequence, tip angle variations due to b1 inhomogeneity can affect the contrast of the image. similarly, for inversion recovery pulses, and other t1-dependent methods, will suffer from signal intensity errors and generally lower t1 weighting. this is due to imperfect flip angles throughout the slice, but particularly around the edges of the body, resulting in imperfect magnetization recovery. rf tip angle theory vs reality human body is full of protons and during imaging, the b0 field aligns these individual protons to a net magnetization in the direction of the magnetic field. an rf pulse that is applied perpendicular to the main magnetic field flips the spins to a desired angle. this flip angle scales with the b1 field amplitude. accurate flip angle is crucial because the measured mr signals depend on the flip angle of the protons. however, this theory assumes that the b1 field is homogenous and, therefore, all spins in a slice are flipped an equal amount. in reality, different areas of a slice see different radio frequency fields, leading to different flip angles. one reason this occurs is because the rf wavelength is inversely proportional to b0. so rf wavelength decreases when b0 increases. at b0 fields of 1.5t, rf wavelengths are long compared to the size of the body. but as the main magnetic field is increased, these wavelengths become the same or smaller than the regions of the body being imaged, resulting in flip angle inhomogeneity. in the images of a healthy patient's brain, it can be visually seen how inhomogeneous the fields are at 3t and 7t. on a side note, this isn’t the only cause of b1 inhomogeneity. it could also be due to the rf pulse design, b0 field inhomogeneity, or even patient movement. asymmetrical brightness there is a uniform decrease in signal intensity along the frequency encoding axis. signal drop-off is due to filters that are too tight about the signal band. some of the signal generated by the imaged section is, thereby, inappropriately rejected. a similar artifact may be caused by non-uniformity in slice thickness. rf noise rf pulses and precessional frequencies of mri instruments occupy the same frequency bandwidth as common sources such as tv, radio, fluorescent lights and computers. stray rf signals can cause various artifacts. narrow-band noise is projected perpendicular to the frequency- encoding direction. broadband noise disrupts the image over a much larger area. appropriate site planning, proper installation and rf shielding (faraday cage) eliminate stray rf interference. zero line and star artifacts a bright linear signal in a dashed pattern that decreases in intensity across the screen and can occur as a line or star