isoxicam isoxicam isoxicam is a nonsteroidal anti-inflammatory drug (nsaid) that was taken or applied to reduce inflammation and as an analgesic reducing pain in certain conditions. the drug was introduced in 1983 by the warner-lambert company. isoxicam is a chemical analog of piroxicam (feldene) which has a pyridine ring in lieu of an isoxazole ring. in 1985 isoxicam was withdrawn from the french market, due to adverse effects, namely toxic epidermal necrolysis (lyell syndrome) resulting in death. although these serious side effects were observed only in france, the drug was withdrawn worldwide. isoxicamclinical datatrade namesmaxicamatc codem01ac03 (who) (withdrawn)identifierscas number34552-84-6pubchem cid54677972drugbankdb08942 ychemspider10442695 nunii8xu734c4ngkeggd04639 ychebichebi:chebi:76163 ncomptox dashboard (epa)dtxsid0045462 echa infocard100.047.334 chemical and physical dataformulac14h13n3o5smolar mass335.33 g·mol−13d model (jsmol)interactive image smiles cc1=cc(=no1)nc(=o)c2=c(c3=cc=cc=c3s(=o)(=o)n2c)o