androgen suppression androgen suppression androgen suppression, also known as testosterone suppression, is a medical treatment to suppress or block the production or action of male sex hormones, typically in order to attempt to treat certain types of cancer that rely upon male hormones for its growth. androgen suppressionother namestestosterone suppression; androgen ablation; androgen deprivation this is done by having the testicles removed, by taking female sex hormones, or by taking drugs called antiandrogens. androgen suppression is employed in androgen deprivation therapy for prostate cancer and in feminizing hormone therapy in transgender women, among other androgen-dependent indications.