clofoctol clofoctol clofoctol is a bacteriostatic antibiotic. it is used in the treatment of respiratory tract and ear, nose and throat infections caused by gram-positive bacteria. it has been marketed in france till 2005 under the trade name octofene and in italy as gramplus. clofoctolclinical dataahfs/drugs.cominternational drug namesroutes ofadministrationrectal (suppository)atc codej01xx03 (who) pharmacokinetic databioavailability98%metabolismhepatic glucuronidationexcretionbiliaryidentifiers iupac name 2--4-(2,4,4-trimethylpentan-2-yl)phenol cas number37693-01-9 ypubchem cid2799chemspider2697 yunii704083ni0rkeggd07244 ychemblchembl1476605comptox dashboard (epa)dtxsid5045889 echa infocard100.048.739 chemical and physical dataformulac21h26cl2omolar mass365.34 g·mol−13d model (jsmol)interactive image smiles clc1cc(cl)ccc1cc2cc(ccc2o)c(c)(c)cc(c)(c)c inchi inchi=1s/c21h26cl2o/c1-20(2,3)13-21(4,5)16-7-9-19(24)15(11-16)10-14-6-8-17(22)12-18(14)23/h6-9,11-12,24h,10,13h2,1-5h3 ykey:hqvzoorkdncgck-uhfffaoysa-n y (verify) it is only functional against gram-positive bacteria. it penetrates into human lung tissue. apteeus is developing clofoctol as a potential therapy against sars-cov-2.