grl-0617 grl-0617 grl-0617 is a drug which is one of the first compounds discovered that acts as a selective small-molecule inhibitor of the protease enzyme papain-like protease (plpro) found in some pathogenic viruses, including the coronavirus sars-cov-2. it has been shown to inhibit viral replication in silico and in vitro. grl-0617identifiers iupac name 5-amino-2-methyl-n-benzamide cas number1093070-16-6 ypubchem cid24941262iuphar/bps11078drugbankdb08656chemspider24617535uniigrl-0617chebichebi:167176chemblchembl549695chemical and physical dataformulac20h20n2omolar mass304.393 g·mol−13d model (jsmol)interactive image smiles cc1=c(c=c(c=c1)n)c(=o)n(c)c2=cc=cc3=cc=cc=c32 inchi inchi=1s/c20h20n2o/c1-13-10-11-16(21)12-19(13)20(23)22-14(2)17-9-5-7-15-6-3-4-8-18(15)17/h3-12,14h,21h2,1-2h3,(h,22,23)/t14-/m1/s1key:uverbunncokgnz-cqszacivsa-n