pyroglutamyl-peptidase i pyroglutamyl-peptidase i pyroglutamyl-peptidase i (ec 3.4.19.3, also known as pyrrolidonyl peptidase, is an enzyme (a cysteine peptidase) found in bacteria, plants and animals. pyroglutamyl-peptidase iidentifiersec no.3.4.19.3cas no.9075-21-2 databasesintenzintenz viewbrendabrenda entryexpasynicezyme viewkeggkegg entrymetacycmetabolic pathwaypriamprofilepdb structuresrcsb pdb pdbe pdbsumsearchpmcarticlespubmedarticlesncbiproteins it can be used to distinguish certain streptococcal organisms. other names are 5-oxoprolyl-peptidase, pyrase, pyrrolidonyl arylamidase, pyroglutamate aminopeptidase, pyroglutamyl aminopeptidase, l-pyroglutamyl peptide hydrolase, pyrrolidone-carboxyl peptidase, pyrrolidone-carboxylate peptidase, pyrrolidonyl peptidase, l-pyrrolidonecarboxylate peptidase, pyroglutamidase, pyrrolidonecarboxylyl peptidase) is an enzyme. this enzyme catalyses the following chemical reaction release of an n-terminal pyroglutamyl group from a polypeptide, the second amino acid generally not being pro human gene pgpep1