troleandomycin troleandomycin troleandomycin (tao for short) is a macrolide antibiotic. it was sold in italy (branded triocetin) and turkey (branded tekmisin). it is no longer sold in italy as of 2018. troleandomycinclinical dataahfs/drugs.commultum consumer informationmedlineplusa604026atc codej01fa08 (who) identifiers iupac name (3r,5r,6r,7s,8r,11r,12s,13r,14s,15s)-12--14--5,7,8,11,13,15-hexamethyl-4,10-dioxo-1,9-dioxaspirohexadec-6-yl acetate cas number2751-09-9 ypubchem cid5284630drugbankdb01361 ychemspider4447675 yuniic4dz64560dkeggd01322 nchebichebi:45735 nchemblchembl564085 npdb ligandtao (pdbe, rcsb pdb)comptox dashboard (epa)dtxsid2023721 echa infocard100.018.539 chemical and physical dataformulac41h67no15molar mass813.979 g·mol−13d model (jsmol)interactive image smiles o=c(o4(n(c)c)c(o4o3((o1o((oc(=o)c)(oc)c1)c)(c(=o)o(c)(c)(oc(=o)c)(c(=o)2(oc2)c3c)c)c)c)c)c inchi inchi=1s/c41h67no15/c1-19-17-41(18-49-41)38(46)23(5)34(53-27(9)43)21(3)25(7)52-39(47)24(6)35(56-32-16-31(48-14)36(26(8)51-32)54-28(10)44)22(4)33(19)57-40-37(55-29(11)45)30(42(12)13)15-20(2)50-40/h19-26,30-37,40h,15-18h2,1-14h3/t19-,20+,21-,22+,23+,24+,25+,26-,30-,31-,32-,33-,34-,35-,36-,37+,40-,41-/m0/s1 ykey:lqclvbqbtuvceq-mcqaqmiosa-n y ny (what is this?) (verify) the drug's mode of action is to bind to the ribosome, specifically in the tunnel through which the newly formed peptide egresses, thereby halting protein synthesis. troleandomycin is a cyp3a4 inhibitor that may cause drug interactions.