bw373u86 bw373u86 (+)-bw373u86 is an opioid analgesic drug used in scientific research. bw373u86clinical dataother names(+)-bw373u86identifiers iupac name 4--(3-hydroxyphenyl)methyl]-n,n-diethylbenzamide cas number150428-54-9 ypubchem cid119029chemspider106357 nuniirr2qfn29k7chemblchembl25230 ncomptox dashboard (epa)dtxsid00933945 chemical and physical dataformulac27h37n3o2molar mass435.612 g·mol−13d model (jsmol)interactive image smiles ccn(cc)c(=o)c1=cc=c(c=c1)c(c2=cc(=cc=c2)o)n3cc(n(cc3c)cc=c)c inchi inchi=1s/c27h37n3o2/c1-6-16-29-18-21(5)30(19-20(29)4)26(24-10-9-11-25(31)17-24)22-12-14-23(15-13-22)27(32)28(7-2)8-3/h6,9-15,17,20-21,26,31h,1,7-8,16,18-19h2,2-5h3/t20-,21+,26-/m1/s1 nkey:lbldmhbsvivjpm-yzihrlcosa-n n ny (what is this?) (verify) bw373u86 is a selective agonist for the δ-opioid receptor, with approximately 15x stronger affinity for the δ-opioid than the μ-opioid receptor. it has potent analgesic and antidepressant effects in animal studies. in studies on rats, bw373u86 appears to protect heart muscle cells from apoptosis in conditions of ischemia (oxygen deprivation, such as in heart attack). the mechanism for this is complex and may be separate from its delta agonist effects.