sacubitrilat sacubitrilat sacubitrilat (inn; or lbq657) is the active metabolite of the antihypertensive drug sacubitril, which is used in the treatment of heart failure. sacubitrilatclinical dataother nameslbq657atc codenoneidentifiers iupac name (2r,4s)-5-(4-biphenylyl)-4--2-methylpentanoic acid cas number149709-44-4pubchem cid10430040chemspider8605468uniispi5pbf81schemblchembl417007pdb ligand6ld (pdbe, rcsb pdb)chemical and physical dataformulac22h25no5molar mass383.444 g·mol−13d model (jsmol)interactive image smiles c(c(cc1=cc=c(c=c1)c2=cc=cc=c2)nc(=o)ccc(=o)o)c(=o)o inchi inchi=1s/c22h25no5/c1-15(22(27)28)13-19(23-20(24)11-12-21(25)26)14-16-7-9-18(10-8-16)17-5-3-2-4-6-17/h2-10,15,19h,11-14h2,1h3,(h,23,24)(h,25,26)(h,27,28)/t15-,19+/m1/s1key:dobnvufhfmvmdb-befaxecrsa-n