etidocaine etidocaine etidocaine, marketed under the trade name duranest, is an amide-type local anesthetic given by injection during surgical procedures and labor and delivery. etidocaine has a long duration of activity, and the main disadvantage of using during dentistry is increased bleeding during surgery. etidocaineclinical datatrade namesduranestahfs/drugs.commicromedex detailed consumer informationmedlineplusa603026pregnancycategory au: b1 routes ofadministrationparenteralatc coden01bb07 (who) legal statuslegal status us: ℞-only pharmacokinetic databioavailabilityn/ametabolismhepaticelimination half-life2.5 hoursexcretionrenalidentifiers iupac name n-(2,6-dimethylphenyl)-2-(ethyl(propyl)amino)butanamide cas number36637-18-0 npubchem cid37497iuphar/bps2621drugbankdb08987 nchemspider34400 yuniii6cqm0f31vkeggd04095 ychebichebi:4904 ychemblchembl492 ycomptox dashboard (epa)dtxsid1023027 echa infocard100.048.296 chemical and physical dataformulac17h28n2omolar mass276.424 g·mol−13d model (jsmol)interactive image smiles o=c(nc1c(c)cccc1c)c(cc)n(cc)ccc inchi inchi=1s/c17h28n2o/c1-6-12-19(8-3)15(7-2)17(20)18-16-13(4)10-9-11-14(16)5/h9-11,15h,6-8,12h2,1-5h3,(h,18,20) ykey:vtusivbdocdnhs-uhfffaoysa-n y ny (what is this?) (verify) synthesis patent: 2-bromobutyryl chloride synthesis: the amide reaction between 2,6-xylidine (1) and 2-bromobutyryl chloride (2) gives 2-bromo-n-(2,6-dimethylphenyl)butanamide (3). alkylation with n-ethylpropylamine (4) gives etidocaine (5).