cefacetrile cefacetrile cefacetrile (inn, also spelled cephacetrile) is a broad-spectrum first generation cephalosporin antibiotic effective in gram-positive and gram-negative bacterial infections. it is a bacteriostatic antibiotic. cefacetrile is marketed under the trade names celospor, celtol, and cristacef, and as vetimast for the treatment of mammary infections in lactating cows. cefacetrileclinical datatrade namescelospor, celtol, cristacefahfs/drugs.cominternational drug namesroutes ofadministrationintravenous, intramuscular, intramammaryatc codej01db10 (who) qj51db10 (who)legal statuslegal status in general: ℞ (prescription only) pharmacokinetic dataprotein binding23 to 38%elimination half-life1.2 hoursexcretionrenal (72%)identifiers iupac name (6r,7r)-3-(acetyloxymethyl)-7--8-oxo-5-thia-1-azabicyclooct-2-ene-2-carboxylic acid cas number10206-21-0 ypubchem cid91562drugbankdb01414 ychemspider82675 yuniifdm21qq344keggd07629 ychemblchembl2104099comptox dashboard (epa)dtxsid0022779 echa infocard100.030.449 chemical and physical dataformulac13h13n3o6smolar mass339.32 g·mol−13d model (jsmol)interactive image smiles o=c2n1/c(=c(\cs12nc(=o)cc#n)coc(=o)c)c(=o)o inchi inchi=1s/c13h13n3o6s/c1-6(17)22-4-7-5-23-12-9(15-8(18)2-3-14)11(19)16(12)10(7)13(20)21/h9,12h,2,4-5h2,1h3,(h,15,18)(h,20,21)/t9-,12-/m1/s1 ykey:rrymaquwdliupv-bxkdbhetsa-n y (verify) synthesis cefacetrile synthesis: nl 6600586 (1966 to ciba-geigy). it was made by reacting 7-aca (7-aminocephalosporanic acid) with cyanoacetyl chloride in the presence of tributylamine.