sublingual papilla sublingual papilla the sublingual papilla or sublingual fold is a small fold of soft tissue located on each side of the frenulum linguae binding the lips to the gums within the mouth. the sublingual papilla marks the site of the sublingual gland with its major sublingual duct and its minor sublingual ducts opening upon the papilla. sublingual papillathe sublingual fold, as identified in this 1906 diagramdetailsidentifierslatinplica sublingualista98a05.1.01.113ta22789fma54660anatomical terminology clinical significance mouth ulcer on the sublingual papilla in cases of pathology, papillotomy procedures are undertaken for cases of obstructive salivary gland diseases. the appearance of papillae may be influenced by the underlying pathology. based on the classification proposed by anicin et al., papilla typology affects the duration of sialendoscope introduction and may influence the frequency of intraoperative complications of sialendoscopy.