methylscopolamine bromide methylscopolamine bromide methylscopolamine or methscopolamine, usually provided as the bromide or nitrate salt, is an oral medication used along with other medications to treat peptic ulcers by reducing stomach acid secretion. proton pump inhibitors and antihistamine medications have made this use obsolete. it can also be used for stomach or intestinal spasms, to reduce salivation, and to treat motion sickness. methscopolamine is also commonly used as a drying agent, to dry up post-nasal drip, in cold, irritable bowel syndrome and allergy medications methylscopolamine bromideclinical datatrade namespamine, extendryl, allerx, resconahfs/drugs.commonographmedlineplusa606008atc codea03bb03 (who) s01fa03 (who)pharmacokinetic dataelimination half-life3–4 hrsidentifiers iupac name (1r,2s,4r,5s,7r)--9,9-dimethyl-3-oxa-9-azoniatricyclononane cas number155-41-9pubchem cid441342drugbankdb00462 ychemspider21106347 yuniirtn51lk7wlchemblchembl376897 ycomptox dashboard (epa)dtxsid2040608 echa infocard100.005.314 chemical and physical dataformulac18h24no4molar mass318.388 g/mol (398.297 g/mol with bromide) g·mol−13d model (jsmol)interactive image smiles oc(c1ccccc1)c(=o)o2c3(c)(c)(c2)4o34 inchi inchi=1s/c18h24no4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20h,8-10h2,1-2h3/q+1/t12-,13-,14-,15+,16-,17+/m1/s1 ykey:lzcoqtdxkcnbee-ikifyqgpsa-n y (verify) methscopolamine, a methylated derivative of scopolamine, is a muscarinic antagonist structurally similar to the neurotransmitter acetylcholine. its mechanism of action involves blocking the muscarinic acetylcholine receptors. it was patented in 1902 and approved for medical use in 1947. methscopolamine is an fda-approved analog to hyoscine butylbromide. brand names brand names include extendryl, allerx, rescon, pamine.