zinc17988990 zinc17988990 zinc17988990 is a drug which acts as a potent and selective inhibitor for the trpv5 calcium channel, with an ic50 of 177 nm and high selectivity for trpv5 over trpv6 and the other subtypes of trpv. it is the first selective inhibitor to be developed for trpv5, and may be useful for modulating calcium reabsorption in the kidneys. zinc17988990identifiers iupac name (4-oxo-5-phenyl-3h-thienopyrimidin-2-yl)methyl 3-(3-oxo-1,4-benzoxazin-4-yl)propanoate pubchem cid27791261chemspider22546450chemical and physical dataformulac24h19n3o5smolar mass461.49 g·mol−13d model (jsmol)interactive image smiles c1c(=o)n(c2=cc=cc=c2o1)ccc(=o)occ3=nc4=c(c(=cs4)c5=cc=cc=c5)c(=o)n3 inchi inchi=1s/c24h19n3o5s/c28-20-13-31-18-9-5-4-8-17(18)27(20)11-10-21(29)32-12-19-25-23(30)22-16(14-33-24(22)26-19)15-6-2-1-3-7-15/h1-9,14h,10-13h2,(h,25,26,30)key:yofcrywwkqmpew-uhfffaoysa-n