granuloma multiforme granuloma multiforme granuloma multiforme is a cutaneous condition most commonly seen in central africa, and rarely elsewhere, characterized by skin lesions that are on the upper trunk and arms in sun-exposed areas.: 707 it may be confused with tuberculoid leprosy, with which it has clinical similarities. the condition was first noted by gosset in the 1940s, but it was not until 1964 that leiker coined the term to describe "a disease resembling leprosy" in his study in nigeria. granuloma multiformeother namesmkar disease and granuloma multiforme (leiker)specialtydermatology