dexketoprofen dexketoprofen dexketoprofen is a nonsteroidal anti-inflammatory drug (nsaid). it is manufactured by menarini, under the tradename keral. it is available in the uk, as dexketoprofen trometamol, as a prescription-only drug and in latin america as enantyum, produced by menarini. also, in italy and spain it is available as an over-the-counter drug (otc) under the trade name enandol or enantyum. in hungary it is available from a pharmacy as “ketodex”. in latvia, lithuania and estonia it is available as an otc under the tradename dolmen in mexico it is available in tablet form as "stadium" made by menarini. it is the dextrorotatory stereoisomer of ketoprofen. dexketoprofenclinical dataahfs/drugs.cominternational drug namesatc codem01ae17 (who) m02aa27 (who)legal statuslegal status uk: pom (prescription only) identifiers iupac name (2s)-2-propanoic acid cas number22161-81-5 npubchem cid667550drugbankdb09214 ychemspider580922 nunii6kd9e78x68keggd07269 ychebichebi:76128 nchemblchembl75435 ncomptox dashboard (epa)dtxsid40905141 echa infocard100.118.639 chemical and physical dataformulac16h14o3molar mass254.285 g·mol−13d model (jsmol)interactive image smiles c(c1cccc(c1)c(=o)c2ccccc2)c(=o)o inchi inchi=1s/c16h14o3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11h,1h3,(h,18,19)/t11-/m0/s1 nkey:dkywvdodhfezim-nshdsacasa-n n ny (what is this?) (verify) chemistry dexketoprofen is the (s)-enantiomer of ketoprofen. technically it is a chiral switch of (±)-ketoprofen. the switch was done for a faster onset of action, a better therapeutic value. medical uses short-term treatment of mild to moderate pain, including dysmenorrhoea. it is also used for migraines and knee pain. side effects it may cause dizziness, and patients should not, therefore, drive or operate heavy machinery or vehicles until they are familiar with how dexketoprofen affects them. concomitant use of alcohol and other sedatives may potentiate this effect. in a small subset of individuals the dizziness may be intolerable and require transition to an alternative treatment. pharmacology dexketoprofen belongs to a class of medicines called nsaids. it works by blocking the action of a substance in the body called cyclo-oxygenase, which is involved in the production of chemicals in the body called prostaglandins. prostaglandins are produced in response to injury or certain diseases and would otherwise go on to cause swelling, inflammation and pain. by blocking cyclo-oxygenase, dexketoprofen prevents the production of prostaglandins and therefore reduces inflammation and pain. along with peripheral analgesic action, it possesses central analgesic action.