clopimozide clopimozide clopimozide (r-29,764) is a typical antipsychotic drug of the diphenylbutylpiperidine class. it is very potent and has an extremely long duration of action, lasting at least one week with a single dose. it was developed by janssen pharmaceutica but was never marketed. clopimozideclinical dataatc codenoneidentifiers iupac name 3--4-piperidyl]-6-chloro-1h-benzimidazol-2-one cas number53179-12-7pubchem cid65449chemspider58909unii7c6ta32sd2keggd02649chemblchembl2104161comptox dashboard (epa)dtxsid60201238 chemical and physical dataformulac28h28clf2n3omolar mass496.00 g·mol−13d model (jsmol)interactive image smiles fc1ccc(cc1)c(c2ccc(f)cc2)cccn5ccc(n4c3ccc(cl)cc3nc4=o)cc5 inchi inchi=1s/c28h28clf2n3o/c29-21-7-12-27-26(18-21)32-28(35)34(27)24-13-16-33(17-14-24)15-1-2-25(19-3-8-22(30)9-4-19)20-5-10-23(31)11-6-20/h3-12,18,24-25h,1-2,13-17h2,(h,32,35)key:jczyxtvbwhawll-uhfffaoysa-n synthesis also used for: domperidone, halopemide & axamozide. is also used for: amperozide, fluspirilene, pimozide, penfluridol, lidoflazine & r 1624. patent (ex viii): the alkylation between 5-chloro-1-(4-piperidyl)-2-benzimidazolinone (1) and 1,1'-(4-chlorobutylidene)bis(4-fluorobenzene) (2) gives clopimozide (3).