climbazole climbazole climbazole is a topical antifungal agent commonly used in the treatment of human fungal skin infections such as dandruff, seborrhoeic dermatitis and eczema. climbazole has shown a high in vitro and in vivo efficacy against malassezia spp. that appear to play an important role in the pathogenesis of dandruff. its chemical structure and properties are similar to other fungicides such as ketoconazole and miconazole. climbazoleclinical dataroutes ofadministrationtopicalatc codenoneidentifiers iupac name (rs)-1-(4-chlorophenoxy)-1-imidazol-1-yl-3,3-dimethylbutan-2-one cas number38083-17-9 ypubchem cid37907chemspider34752 nunii9n42cw7i54chebichebi:83499 nchemblchembl1437764 ncomptox dashboard (epa)dtxsid6046555 echa infocard100.048.870 chemical and physical dataformulac15h17cln2o2molar mass292.76 g·mol−13d model (jsmol)interactive imagechiralityracemic mixture smiles cc(c)(c)c(=o)c(n1ccnc1)oc2ccc(cc2)cl inchi inchi=1s/c15h17cln2o2/c1-15(2,3)13(19)14(18-9-8-17-10-18)20-12-6-4-11(16)5-7-12/h4-10,14h,1-3h3 nkey:owegwhbocfmblp-uhfffaoysa-n n ny (what is this?) (verify) indications and formulations it is most commonly found as an active ingredient in otc anti-dandruff and anti-fungal products, including shampoos, lotions and conditioners. it may be accompanied by other active ingredients such as zinc pyrithione or triclosan. side effects may cause localized irritation of the skin with symptoms including redness, rashes and itching.