clocortolone pivalate clocortolone pivalate clocortolone pivalate (brand names cilder, cloderm, purantix), also known as clocortolone trimethylacetate, is a synthetic glucocorticoid corticosteroid and corticosteroid ester which is marketed in the united states and austria. it is the c21 pivalate (trimethylacetate) ester of clocortolone, and acts as a prodrug of clocortolone in the body. clocortolone pivalateclinical datatrade namescilder, cloderm, purantixother namesclocortolone trimethylacetate; cl-68; sh-863; 9α-chloro-6α-fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-pivalatedrug classcorticosteroid; glucocorticoididentifiers iupac name phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanoate cas number34097-16-0pubchem cid5282493chemspider4445634uniiqbl8izh14xkeggd02287chebichebi:59583chemblchembl1200975comptox dashboard (epa)dtxsid0045460 echa infocard100.047.099 chemical and physical dataformulac27h36clfo5molar mass495.03 g·mol−13d model (jsmol)interactive image smiles c1c23c(c4=cc(=o)c=c4(3((c2(1c(=o)coc(=o)c(c)(c)c)c)o)cl)c)f inchi inchi=1s/c27h36clfo5/c1-14-9-16-17-11-19(29)18-10-15(30)7-8-26(18,6)27(17,28)21(32)12-25(16,5)22(14)20(31)13-34-23(33)24(2,3)4/h7-8,10,14,16-17,19,21-22,32h,9,11-13h2,1-6h3/t14-,16+,17+,19+,21+,22-,25+,26+,27+/m1/s1key:sxyzqzlhaihkky-gstupefvsa-n