caroxazone caroxazone caroxazone (surodil, timostenil) is an antidepressant which was formerly used for the treatment of depression but is now no longer marketed. it acts as a reversible monoamine oxidase inhibitor (rima) of both mao-a and mao-b subtypes, with five-fold preference for the latter. caroxazoneclinical datapregnancycategory ? routes ofadministrationoralatc codenonelegal statuslegal status in general: ℞ (prescription only) identifiers iupac name 2-(2-oxo-4h-1,3-benzoxazin-3-yl)acetamide cas number18464-39-6pubchem cid29083chemspider27057unii807n226mnlchemblchembl2104164comptox dashboard (epa)dtxsid10171598 echa infocard100.038.481 chemical and physical dataformulac10h10n2o3molar mass206.201 g·mol−13d model (jsmol)interactive image smiles o=c(n)cn2c(=o)oc1ccccc1c2 synthesis caroxazone synthesis: synthesis starts by reductive amination of salicylaldehyde and glycinamide to give 3. the synthesis is completed by reaction with phosgene and nahco3.