albinism–deafness syndrome albinism–deafness syndrome albinism–deafness syndrome is a condition characterized by congenital neural deafness and a severe or extreme piebald-like phenotype with extensive areas of hypopigmentation. albinism–deafness syndromeother nameswoolf syndrome and ziprkowski–margolis syndromealbinism–deafness syndrome is inherited in an x-linked recessive manner a locus at xq26.3-q27.i has been suggested. it has been suggested that it is a form of waardenburg syndrome type ii.