abexinostat abexinostat abexinostat (inn, formerly pci-24781) is an experimental drug candidate for cancer treatment. it was developed by pharmacyclics and licensed to xynomic. and is in phase ii clinical trials for b-cell lymphoma. pre-clinical study suggests the potential for treatment of different types of cancer as well. abexinostat names iupac name 3--n--1-benzofuran-2-carboxamide other names pci-24781; cra-024781 identifiers cas number 783355-60-2 y783356-67-2 (hcl) y 3d model (jsmol) interactive image chembl chembl2103863 n chemspider 9924562 y echa infocard 100.241.399 kegg d10060 n pubchem cid 11749858 unii iyo470654u yt1e6tm0svg (hcl) y comptox dashboard (epa) dtxsid30229005 inchi inchi=1s/c21h23n3o5/c1-24(2)13-17-16-5-3-4-6-18(16)29-19(17)21(26)22-11-12-28-15-9-7-14(8-10-15)20(25)23-27/h3-10,27h,11-13h2,1-2h3,(h,22,26)(h,23,25) ykey: mauconchvwbmhk-uhfffaoysa-n yinchi=1/c21h23n3o5/c1-24(2)13-17-16-5-3-4-6-18(16)29-19(17)21(26)22-11-12-28-15-9-7-14(8-10-15)20(25)23-27/h3-10,27h,11-13h2,1-2h3,(h,22,26)(h,23,25)key: mauconchvwbmhk-uhfffaoyam smiles o=c(no)c3ccc(occnc(=o)c2oc1ccccc1c2cn(c)c)cc3 properties chemical formula c21h23n3o5 molar mass 397.431 g·mol−1 except where otherwise noted, data are given for materials in their standard state (at 25 °c , 100 kpa). n verify (what is yn ?) infobox references abexinostat exerts its effect as a pan-histone deacetylase inhibitor and inhibits rad51, which is involved in repairing dna double strand breaks.