nitecapone nitecapone nitecapone (inn; or-462) is a drug which acts as a selective inhibitor of the enzyme catechol o-methyl transferase (comt). it was patented as an antiparkinson medication but was never marketed. nitecaponeclinical dataatc codenoneidentifiers iupac name 3-pentane-2,4-dione cas number116313-94-1pubchem cid5464105chemspider4576539unii98bs722498keggd03241chemblchembl167055comptox dashboard (epa)dtxsid80151347 chemical and physical dataformulac12h11no6molar mass265.221 g·mol−13d model (jsmol)interactive image smiles (=o)c1cc(\c=c(/c(=o)c)c(=o)c)cc(o)c1o inchi inchi=1s/c12h11no6/c1-6(14)9(7(2)15)3-8-4-10(13(18)19)12(17)11(16)5-8/h3-5,16-17h,1-2h3key:upmrzalmhvucin-uhfffaoysa-n