thiopropazate thiopropazate thiopropazate (artalan, dartal, dartalan, dartan) is a typical antipsychotic of the phenothiazine class. it is a prodrug to perphenazine. thiopropazateclinical datatrade namesartalan, dartal, dartalan, dartanatc coden05ab05 (who) identifiers iupac name 2-piperazin-1-yl]ethyl acetate cas number84-06-0 ypubchem cid6762chemspider6504 yunii0jfy081q2xkeggd09216 ychebichebi:59119 ychemblchembl1697851comptox dashboard (epa)dtxsid6023654 echa infocard100.001.376 chemical and physical dataformulac23h28cln3o2smolar mass446.01 g·mol−13d model (jsmol)interactive image smiles cc(=o)occn1ccn(cc1)cccn2c3=cc=cc=c3sc4=c2c=c(c=c4)cl inchi inchi=1s/c23h28cln3o2s/c1-18(28)29-16-15-26-13-11-25(12-14-26)9-4-10-27-20-5-2-3-6-22(20)30-23-8-7-19(24)17-21(23)27/h2-3,5-8,17h,4,9-16h2,1h3 ykey:aiuhrqhvwsutgj-uhfffaoysa-n y (verify) thiopropazate is manufactured by searle (us, uk) & boehringer mannheim (germany) thiopropazate is sold by chembase, aaa chemistry, zinc, akos consulting & solutions, boc sciences, chemfrog, and chemmol synthesis thieme patent: the alkylation of 2-chloro-10-(3-chloropropyl)phenothiazine (1) with piperazine (2) gives n-desmethylprochlorperazine (3). further alkylation with 2-bromoethyl acetate (4) gives thiopropazate (5).