vgx-1027 vgx-1027 vgx-1027 (git-27) is a drug which acts as an immunomodulator. it acts by blocking downstream signalling of the toll-like receptors tlr2, tlr4 and tlr6, and thereby reducing production of various cytokines, including interleukins and tnf-α. in animal studies it has antiinflammatory effects and has been investigated for conditions such as arthritis and lung inflammation. vgx-1027identifiers iupac name 2-(3-phenyl-4,5-dihydro-1,2-oxazol-5-yl)acetic acid cas number6501-72-0 ypubchem cid10798271chemspider8973577uniiakt814n13rchemblchembl1320667comptox dashboard (epa)dtxsid50445023 chemical and physical dataformulac11h11no3molar mass205.213 g·mol−13d model (jsmol)interactive image smiles c1c(on=c1c2=cc=cc=c2)cc(=o)o inchi inchi=1s/c11h11no3/c13-11(14)7-9-6-10(12-15-9)8-4-2-1-3-5-8/h1-5,9h,6-7h2,(h,13,14)key:mufjhyrcihhatf-uhfffaoysa-n