devazepide devazepide devazepide (l-364,718, mk-329) is benzodiazepine drug, but with quite different actions from most benzodiazepines, lacking affinity for gabaa receptors and instead acting as an ccka receptor antagonist. it increases appetite and accelerates gastric emptying, and has been suggested as a potential treatment for a variety of gastrointestinal problems including dyspepsia, gastroparesis and gastric reflux. it is also widely used in scientific research into the ccka receptor. devazepideclinical dataatc codenoneidentifiers iupac name n-(1-methyl-2-oxo-5-phenyl-3h-1,4-benzodiazepin-3-yl)-1h-indole-2-carboxamide cas number103420-77-5 ypubchem cid443375iuphar/bps878chemspider391607 nuniije6p7qy7nhkeggd02693 ychemblchembl9506 ncomptox dashboard (epa)dtxsid2046092 echa infocard100.208.547 chemical and physical dataformulac25h20n4o2molar mass408.461 g·mol−13d model (jsmol)interactive image smiles o=c(c2cc1ccccc12)n3/n=c(\c4ccccc4n(c3=o)c)c5ccccc5 inchi inchi=1s/c25h20n4o2/c1-29-21-14-8-6-12-18(21)22(16-9-3-2-4-10-16)27-23(25(29)31)28-24(30)20-15-17-11-5-7-13-19(17)26-20/h2-15,23,26h,1h3,(h,28,30)/t23-/m1/s1 nkey:nfhrqqkpebfujk-hszrjfapsa-n n ny (what is this?) (verify) synthesis devazepide is synthesised in a similar manner to other benzodiazepines.