n-nitrosodimethylamine n-nitrosodimethylamine n-nitrosodimethylamine (ndma), also known as dimethylnitrosamine (dmn), is an organic compound with the formula (ch3)2nno. it is one of the simplest members of a large class of n-nitrosamines. it is a volatile yellow oil. ndma has attracted wide attention as being highly hepatotoxic and a known carcinogen in laboratory animals. not to be confused with mdma, nmda, or n-nitrosodiethylamine. n-nitrosodimethylamine names preferred iupac name n,n-dimethylnitrous amide identifiers cas number 62-75-9 y 3d model (jsmol) interactive image chebi chebi:35807 n chembl chembl117311 n chemspider 5894 n echa infocard 100.000.500 ec number 200-549-8 kegg c14704 n mesh dimethylnitrosamine pubchem cid 6124 rtecs number iq0525000 unii m43h21io8r y un number 3382 comptox dashboard (epa) dtxsid7021029 inchi inchi=1s/c2h6n2o/c1-4(2)3-5/h1-2h3 nkey: umfjahhvkncglg-uhfffaoysa-n n smiles cn(c)n=o properties chemical formula c2h6n2o molar mass 74.083 g·mol−1 appearance yellow oil odor faint, characteristic density 1.005 g/ml boiling point 153.1 °c; 307.5 °f; 426.2 k solubility in water 290 mg/ml (at 20 °c) log p −0.496 vapor pressure 700 pa (at 20 °c) refractive index (nd) 1.437 thermochemistry std enthalpy ofcombustion (δch⦵298) 1.65 mj/mol hazards occupational safety and health (ohs/osh): main hazards known carcinogen, extremely toxic ghs labelling: pictograms signal word danger hazard statements h301, h330, h350, h372, h411 precautionary statements p260, p273, p284, p301+p310, p310 nfpa 704 (fire diamond) 4 2 0 flash point 61.0 °c (141.8 °f; 334.1 k) lethal dose or concentration (ld, lc): ld50 (median dose) 37.0 mg/kg (oral, rat) niosh (us health exposure limits): pel (permissible) osha-regulated carcinogen rel (recommended) ca idlh (immediate danger) ca related compounds related compounds dimethylaminen-nitrosodiethylamine except where otherwise noted, data are given for materials in their standard state (at 25 °c , 100 kpa). n verify (what is yn ?) infobox references occurrence drinking water of more general concern, ndma can be produced by water treatment by chlorination or chloramination. the question is the level at which it is produced. in the u.s. state of california, the allowable level is 10 nanograms/liter. the canadian province of ontario set the standard at 9 ng/l. the potential problem is greater for recycled water that can contain dimethylamine. further, ndma can form or be leached during treatment of water by anion exchange resins. contamination of drinking water with ndma is of particular concern due to the minute concentrations at which it is harmful, the difficulty in detecting it at these concentrations, and to the difficulty in removing it from drinking water. it does not readily biodegrade, adsorb, or volatilize. as such, it cannot be removed by activated carbon and travels easily through soils. relatively high levels of uv radiation in the 200 to 260 nm range breaks the n–n bond. thus, it can be used to degrade ndma. additionally, reverse osmosis removes approximately 50% of ndma. cured meat ndma is found at low levels in numerous items of human consumption, including cured meat, fish, beer, as well as during use of tobacco products and the inhalation of tobacco smoke. rocket fuel unsymmetrical dimethylhydrazine, a rocket fuel, is a highly effective precursor to ndma: (ch3)2nnh2 + 2 o → (ch3)2nno + h2o groundwater near rocket launch sites often has high levels of ndma. regulation