abadie's sign of exophthalmic goiter abadie's sign of exophthalmic goiter abadie's sign of exophthalmic goiter is a medical sign characterized by spasm of the levator palpebrae superioris muscle with retraction of the upper lid (so that sclera is visible above cornea) seen in graves-basedow disease which, together with exophthalmos causes the bulging eyes appearance. abadie's sign of exophthalmic goiterphoto showing abadie's sign of exopthalmic goiter in a man with graves' diseasedifferential diagnosisgraves-basedow disease it is named for jean marie charles abadie.