(r)-p-isothiocyanatobenzoylecgonine methyl ester (r)-p-isothiocyanatobenzoylecgonine methyl ester (r)-p-isothiocyanatobenzoylecgonine methyl ester (p-isococ) is a cocaine analogue and irreversible (covalent) binding inhibitor of the cocaine receptor, as well as irreversible blocker of dopamine uptake by dat (the latter being unlike its c3 homologue m-isococ). p-isococ also blocks the high-affinity cocaine site in preference to the low-affinity site. (r)-p-isothiocyanato­benzoylecgonine methyl ester names preferred iupac name methyl (1r,2r,3s,5s)-3--8-methyl-8-azabicyclooctane-2-carboxylate other names p-isococ, p-isococ identifiers 3d model (jsmol) interactive image chemspider 26286894 y pubchem cid 71308129 inchi inchi=1s/c18h20n2o4s/c1-20-13-7-8-14(20)16(18(22)23-2)15(9-13)24-17(21)11-3-5-12(6-4-11)19-10-25/h3-6,13-16h,7-9h2,1-2h3/t13-,14+,15-,16+/m0/s1 ykey: jzgfomfcwsmvhi-xuwvnrhrsa-n yinchi=1/c18h20n2o4s/c1-20-13-7-8-14(20)16(18(22)23-2)15(9-13)24-17(21)11-3-5-12(6-4-11)19-10-25/h3-6,13-16h,7-9h2,1-2h3/t13-,14+,15-,16+/m0/s1key: jzgfomfcwsmvhi-xuwvnrhrbq smiles cn12cc1((c2)oc(=o)c3ccc(cc3)n=c=s)c(=o)oc properties chemical formula c18h20n2o4s molar mass 360.427 except where otherwise noted, data are given for materials in their standard state (at 25 °c , 100 kpa). y verify (what is yn ?) infobox references