sappinia diploidea sappinia diploidea sappinia diploidea is a free-living amoeba species. sappinia diploidea scientific classification domain: eukaryota phylum: amoebozoa class: discosea subclass: flabellinia family: thecamoebidae genus: sappinia species: s. diploidea binomial name sappinia diploidea background sappinia can be found worldwide. it usually occurs in elk and buffalo feces, places where farm animals are known to eat, soil containing rotting plants, and fresh water sources. clinical significance it is capable of causing infectious disease in humans. symptoms of sappinia infection symptoms of a sappinia infection include headache, photophobia, nausea or upset stomach, vomiting, blurred vision, and loss of consciousness. a scan of the one, infected patient’s brain also revealed a 2-centimeter tumor-like mass on the back left section of his brain. treatment treatment for the one identified case of sappinia infection included the removal of a tumor in the brain and a series of drugs given to the patient after surgery. this treatment led to the patient’s full recovery.