bifemelane bifemelane bifemelane (inn) (alnert, celeport), or bifemelane hydrochloride (jan), also known as 4-(o-benzylphenoxy)-n-methylbutylamine, is an antidepressant and cerebral activator that is widely used in the treatment of cerebral infarction patients with depressive symptoms in japan, and in the treatment of senile dementia as well. it also appears to be useful in the treatment of glaucoma. bifemelane acts as a monoamine oxidase inhibitor (maoi) of both isoenzymes, with competitive (reversible) inhibition of mao-a (ki = 4.20 μm) (making it a reversible inhibitor of monoamine oxidase a (rima)) and non-competitive (irreversible) inhibition of mao-b (ki = 46.0 μm), and also acts (weakly) as a norepinephrine reuptake inhibitor. the drug has nootropic, neuroprotective, and antidepressant-like effects in animal models, and appears to enhance the cholinergic system in the brain. bifemelaneclinical datatrade namesalnert, celeportother namesmcl-2016ahfs/drugs.cominternational drug namesatc coden06ax08 (who) identifiers iupac name n-methyl-4-butan-1-amine cas number90293-01-9 ypubchem cid2377chemspider2286 yuniiz4501gn13gchemblchembl1192517 ncomptox dashboard (epa)dtxsid1045663 echa infocard100.220.566 chemical and physical dataformulac18h23nomolar mass269.388 g·mol−13d model (jsmol)interactive image smiles o(c1ccccc1cc2ccccc2)ccccnc inchi inchi=1s/c18h23no/c1-19-13-7-8-14-20-18-12-6-5-11-17(18)15-16-9-3-2-4-10-16/h2-6,9-12,19h,7-8,13-15h2,1h3 ykey:qsqqpmhpcbllgx-uhfffaoysa-n y ny (what is this?) (verify)