6α-methylprogesterone 6α-methylprogesterone 6α-methylprogesterone (6α-mp) is a progestin which was never marketed. it has 150% of the progestogenic potency of progesterone. in addition, and in contrast to progesterone, 6α-mp has weak androgenic, antiandrogenic, and synandrogenic actions. 6α-mp is structurally related to medroxyprogesterone acetate (mpa; 6α-methyl-17α-acetoxyprogesterone) and megestrol acetate (mga; 6-dehydro-6-methyl-17α-acetoxyprogesterone), which possess androgenic and/or antiandrogenic activity to varying degrees similarly. mpa is more androgenic than 6α-mp and mga. 6α-methylprogesteroneclinical dataother names6α-methylpregn-4-ene-3,20-dione; 6α-mp; 6-mp; 6mp; nsc-75530drug classprogestogen; progestinidentifiers iupac name (6s,8s,9s,10r,13s,14s,17s)-17-acetyl-6,10,13-trimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopentaphenanthren-3-one cas number903-71-9pubchem cid92847chemspider83815uniiykt998y6uzkeggc14586chebichebi:34476chemblchembl433198chemical and physical dataformulac22h32o2molar mass328.496 g·mol−13d model (jsmol)interactive image smiles c1c23cc(3(cc24(c1=cc(=o)cc4)c)c)c(=o)c inchi inchi=1s/c22h32o2/c1-13-11-16-18-6-5-17(14(2)23)21(18,3)10-8-19(16)22(4)9-7-15(24)12-20(13)22/h12-13,16-19h,5-11h2,1-4h3/t13-,16-,17+,18-,19-,21+,22+/m0/s1key:gnfabwapjfozsf-ktorgglssa-n