1-ethynylcyclohexanol 1-ethynylcyclohexanol 1-ethynylcyclohexanol (ecx) is an alkynyl alcohol derivative which is both a synthetic precursor to, and an active metabolite of the tranquilizer ethinamate, and has similar sedative, anticonvulsant and muscle relaxant effects. it has been sold as a designer drug, first being identified in the uk in march 2012. 1-ethynylcyclohexanolidentifiers iupac name 1-ethynylcyclohexan-1-ol cas number78-27-3 ypubchem cid6525chemspider6277unii6rv04025ehchemblchembl394631comptox dashboard (epa)dtxsid0021757 echa infocard100.001.001 chemical and physical dataformulac8h12omolar mass124.183 g·mol−13d model (jsmol)interactive imagemelting point30–33 °c (86–91 °f) smiles c#cc1(ccccc1)o inchi inchi=1s/c8h12o/c1-2-8(9)6-4-3-5-7-8/h1,9h,3-7h2key:qylfhlnfihbcpr-uhfffaoysa-n preparation synthesis of 1-ethynylcyclohexanol from cyclohexanone. 1-ethynylcyclohexanol can be prepared from cyclohexanone by the reacting it with sodium acetylide in liquid ammonia, followed by an acidic work-up.