pyrazolopyridines pyrazolopyridines the pyrazolopyridines are a group of drugs investigated as anxiolytics which act as positive allosteric modulators of the gabaa receptor via the barbiturate binding site. they include the following compounds: cartazolate (sq-65,396) etazolate (sq-20,009) ici-190,622 tracazolate (ici-136,753) pyrazolopyridine, the base chemical structure of this class.