firm and the other responsible parties. number of chemicals covered in the inventory reach: after enacting reach in the european union, the officials estimated approximately 30,000 cases that have produced or imported at a level of at least 1 metric ton chemicals. tsca: currently more than 82,000 chemicals are in the tsca inventory and 20,000 of them were added after 1979 into the inventory after the epa program started reviewing the existing chemicals. complete risk assessment requirements reach requires chemical companies that produce at level of 1 metric tons per year to conduct risk assessment along with european chemical agency’s review and for the companies that produce more than 10 tons or more per years need to conduct chemical safety assessment for all the chemicals produced. tsca does not require chemical companies to perform risk assessments on new chemicals. however, it allows companies to perform voluntary risk assessments on their new chemicals. for existing chemicals, companies are required to notify the epa immediately of new unpublished information on chemicals that have potential risks but are not required to conduct risk assessments. production quantity disclosure reach requires chemical companies to submit their registration yearly with the information on the overall quantity of production or importing of a chemical in metric tons per year in a technical dossier and immediately report if any significant changes occur in the quantity. tsca: chemical companies must provide the epa a reasonable third year estimate for their new chemicals in total production volume at the time a premanufacture notices is submitted. for every 5 years, the existing chemicals on the tsca inventory and produced at quantities of 25,000 pounds or more must be reported. example of chemical inventories in various countries and regions reach - european union regulation (ec) no 1907/2006 aics - australian inventory of chemical substances dsl - canadian domestic substances list ndsl - canadian non-domestic substances list kecl (korean ecl) - korean existing chemicals list encs (miti) - japanese existing and new chemical substances piccs - philippine inventory of chemicals and chemical substances tsca inventory - us toxic substances control act swiss - giftliste 1 swiss - inventory of notified new substances