halometasone halometasone halometasone is a potent (group iii) synthetic tri-halogenated corticosteroid for topical application possessing pronounced anti-inflammatory, antiexudative, antiepidermoplastic, antiallergic, and antipruritic properties. it has been approved in many european countries including spain, germany, switzerland, austria, netherlands, belgium, and portugal and other regions such as china, hong kong, turkey, israel, south africa and india. halometasoneclinical datatrade namessicortenother names(6s,8s,9r,10s,11s,13s,16r,17r)-2-chloro-6,9-difluoro-11,17-dihydroxy-17-(2-hydroxy-acetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopentaphenanthren-3-oneahfs/drugs.cominternational drug namesroutes ofadministrationtopicalatc coded07ac12 (who) identifiers iupac name (6α,11β,16α)-2-chloro-6,9-difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione cas number50629-82-8 ypubchem cid9846332chemspider8022046 nuniij69z9uu41zchemblchembl1587228 ncomptox dashboard (epa)dtxsid1048382 echa infocard100.051.496 chemical and physical dataformulac22h27clf2o5molar mass444.90 g·mol−13d model (jsmol)interactive image smiles o=c(co)3(o)2(c(o)4(f)/1(\c(=c/c(=o)c(\cl)=c\1)(f)c42c3c)c)c inchi inchi=1s/c22h27clf2o5/c1-10-4-11-12-5-15(24)13-6-16(27)14(23)7-19(13,2)21(12,25)17(28)8-20(11,3)22(10,30)18(29)9-26/h6-7,10-12,15,17,26,28,30h,4-5,8-9h2,1-3h3/t10-,11+,12+,15+,17+,19+,20+,21+,22+/m1/s1 nkey:ggxmrpukbwxvhe-mihlvhiwsa-n n ny (what is this?) (verify) it has been used to treat chronic psoriasis vulgaris and non-infected acute eczematous dermatoses (eczema). one study demonstrated that 0.05% halometasone cream was more effective than 0.05% betamethasone cream in treating dermatitis, though both were well tolerated, with no systemic adverse effects reported.