hemoglobin j hemoglobin j hemoglobin j is an abnormal hemoglobin, an alpha globin gene variant and present in various geographic locations. it was first reported in a black american family in 1956, and later reported from indonesia, india, and other parts of the world. hemoglobin j reported from meerut india shows the mutation of 120th alanine to glutamic acid on alpha chain. hemoglobin j was also reported from chhattisgarh, central india as revealed by lingojwar and coworkers in 2016.