ophelia syndrome ophelia syndrome ophelia is a character in shakespeare's play hamlet. ophelia syndrome, named after her, may refer to: ophelia syndrome, a medical condition characterized by hodgkin lymphoma with autoimmune limbic encephalitis, caused by anti-metabotropic glutamate receptor 5 antibodies (mglur5) ophelia complex, a psychological term this article is issued from wikipedia. the text is licensed under creative commons - attribution - sharealike. additional terms may apply for the media files.