tc-1827 tc-1827 tc-1827 is an orally active, selective agonist of the α4β2 nicotinic receptors. administration of tc-1827 improved memory and learning in a variety of rodents and increased long-term potentiation in hippocampal slices. in addition, the compound was without significant cardiovascular side effects, except for a small, transient rise in arterial blood pressure. the pro-cognitive effects of tc-1827 last much longer than the short half life (0.2 - 1.0 hours) would suggest. tc-1827 names preferred iupac name (2s,4e)-n-methyl-5-(pyrimidin-5-yl)pent-4-en-2-amine identifiers cas number 547741-76-4 y 3d model (jsmol) interactive image chemspider 8329797 pubchem cid 10154289 inchi inchi=1s/c10h15n3/c1-9(11-2)4-3-5-10-6-12-8-13-7-10/h3,5-9,11h,4h2,1-2h3/b5-3+/t9-/m0/s1key: vzntwliijwucep-sgrboosssa-n smiles c(nc)c/c=c/c1=cn=cn=c1 properties chemical formula c10h15n3 molar mass 177.251 g·mol−1 except where otherwise noted, data are given for materials in their standard state (at 25 °c , 100 kpa). infobox references