laudanosine laudanosine laudanosine or n-methyltetrahydropapaverine is a recognized metabolite of atracurium and cisatracurium. laudanosine decreases the seizure threshold, and thus it can induce seizures if present at sufficient threshold concentrations; however such concentrations are unlikely to be produced consequent to chemodegradable metabolism of clinically administered doses of cisatracurium or atracurium. capsule of papaver somniferum showing latex (opium) exuding from incision. laudanosine occurs naturally in small amounts (0.1%) in opium. laudanosine names preferred iupac name (1s)-1--6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline other names n-methyl-1,2,3,4-tetrahydropapaverine identifiers cas number 2688-77-9 y 3d model (jsmol) interactive image chemspider 66114 n echa infocard 100.018.412 ec number 220-253-2 pubchem cid 73397 unii da7r5wvn48 y comptox dashboard (epa) dtxsid30878577 inchi inchi=1s/c21h27no4/c1-22-9-8-15-12-20(25-4)21(26-5)13-16(15)17(22)10-14-6-7-18(23-2)19(11-14)24-3/h6-7,11-13,17h,8-10h2,1-5h3/t17-/m0/s1 nkey: kgpayjzamgediq-krwdzbqosa-n ninchi=1/c21h27no4/c1-22-9-8-15-12-20(25-4)21(26-5)13-16(15)17(22)10-14-6-7-18(23-2)19(11-14)24-3/h6-7,11-13,17h,8-10h2,1-5h3/t17-/m0/s1key: kgpayjzamgediq-krwdzbqobo smiles cn1ccc2cc(c(cc21cc3ccc(c(c3)oc)oc)oc)oc properties chemical formula c21h27no4 molar mass 357.450 g·mol−1 melting point 89 °c (192 °f; 362 k) except where otherwise noted, data are given for materials in their standard state (at 25 °c , 100 kpa). n verify (what is yn ?) infobox references laudanosine also occurs naturally in minute amounts (0.1%) in opium, from which it was first isolated in 1871. partial dehydrogenation of laudanosine will lead to papaverine, the alkaloid found in the opium poppy plant (papaver somniferum). laudanosine is a benzyltetrahydroisoquinoline alkaloid. it has been shown to interact with gaba receptors, glycine receptors, opioid receptors, and nicotinic acetylcholine receptors, but not benzodiazepine or muscarinic receptors, which are also involved in epilepsy and other types of seizures.