palmoplantar hyperhidrosis palmoplantar hyperhidrosis a palmoplantar hyperhidrosis is excessive sweating localized to the palms of the hands and soles of the feet. it is a form of focal hyperhidrosis in that the excessive sweating is limited to a specific region of the body. as with other types of focal hyperhidrosis (e.g. axillary and craniofacial) the sweating tends to worsen during warm weather.