uh-232 uh-232 uh-232 ((+)-uh232) is a drug which acts as a subtype selective mixed agonist-antagonist for dopamine receptors, acting as a weak partial agonist at the d3 subtype, and an antagonist at d2sh autoreceptors on dopaminergic nerve terminals. this causes dopamine release in the brain and has a stimulant effect, as well as blocking the behavioural effects of cocaine. it may also serve as a 5-ht2a receptor agonist, based on animal studies. it was investigated in clinical trials for the treatment of schizophrenia, but unexpectedly caused symptoms to become worse. uh-232clinical dataatc codenoneidentifiers iupac name (1s,2r)-5-methoxy-1-methyl-2-(n,n-propylamino)tetralin cas number95999-12-5 ypubchem cid123696uniiqqyor9s587comptox dashboard (epa)dtxsid70875101 chemical and physical dataformulac18h29nomolar mass275.436 g·mol−13d model (jsmol)interactive image smiles cc2c(n(ccc)ccc)ccc1c2cccc1oc (verify) (+)-aj76 the n-monopropyl derivative (+)-aj76 is an active metabolite of uh-232 and has practically identical effects. (+)-aj76, cas# 85378-82-1, 13755572