show a gradient of size and complexity that roughly follows the evolutionary sequence. all of these brains contain the same set of basic anatomical components, but many are rudimentary in the hagfish, whereas in mammals the foremost part (the telencephalon) is greatly elaborated and expanded. brains are most commonly compared in terms of their size. the relationship between brain size, body size and other variables has been studied across a wide range of vertebrate species. as a rule, brain size increases with body size, but not in a simple linear proportion. in general, smaller animals tend to have larger brains, measured as a fraction of body size. for mammals, the relationship between brain volume and body mass essentially follows a power law with an exponent of about 0.75. this formula describes the central tendency, but every family of mammals departs from it to some degree, in a way that reflects in part the complexity of their behavior. for example, primates have brains 5 to 10 times larger than the formula predicts. predators tend to have larger brains than their prey, relative to body size. the main subdivisions of the embryonic vertebrate brain (left), which later differentiate into structures of the adult brain (right) all vertebrate brains share a common underlying form, which appears most clearly during early stages of embryonic development. in its earliest form, the brain appears as three swellings at the front end of the neural tube; these swellings eventually become the forebrain, midbrain, and hindbrain (the prosencephalon, mesencephalon, and rhombencephalon, respectively). at the earliest stages of brain development, the three areas are roughly equal in size. in many classes of vertebrates, such as fish and amphibians, the three parts remain similar in size in the adult, but in mammals the forebrain becomes much larger than the other parts, and the midbrain becomes very small. the brains of vertebrates are made of very soft tissue. living brain tissue is pinkish on the outside and mostly white on the inside, with subtle variations in color. vertebrate brains are surrounded by a system of connective tissue membranes called meninges that separate the skull from the brain. blood vessels enter the central nervous system through holes in the meningeal layers. the cells in the blood vessel walls are joined tightly to one another, forming the blood–brain barrier, which blocks the passage of many toxins and pathogens (though at the same time blocking antibodies and some drugs, thereby presenting special challenges in treatment of diseases of the brain). neuroanatomists usually divide the vertebrate brain into six main regions: the telencephalon (cerebral hemispheres), diencephalon (thalamus and hypothalamus), mesencephalon (midbrain), cerebellum, pons, and medulla oblongata. each of these areas has a complex internal structure. some parts, such as the cerebral cortex and the cerebellar cortex, consist of layers that are folded or convoluted to fit within the available space. other parts, such as the thalamus and hypothalamus, consist of clusters of many small nuclei. thousands of distinguishable areas can be identified within the vertebrate brain based on fine distinctions of neural structure, chemistry, and connectivity. the main anatomical regions of the vertebrate brain, shown for shark and human. the same parts are present, but they differ greatly in size and shape. although the same basic components are present in all vertebrate brains, some branches of vertebrate evolution have led to substantial distortions of brain geometry, especially in the forebrain area. the brain of a shark shows the basic components in a straightforward way, but in teleost fishes (the great majority of existing fish species), the forebrain has become "everted", like a sock turned inside out. in birds, there are also major changes in forebrain structure. these distortions can make it difficult to match brain components from one species with those of another species. here is a list of some of the most important vertebrate brain components, along with a brief description of their functions as currently understood: