cadaverine cadaverine cadaverine is an organic compound with the formula (ch2)5(nh2)2. classified as diamine, it is a colorless liquid with an unpleasant odor. it is present in small quantities in living organisms but is often associated with the putrefaction of animal tissue. cadaverine skeletal formula ball-and-stick model names preferred iupac name pentane-1,5-diamine other names 1,5-diaminopentane, pentamethylenediamine identifiers cas number 462-94-2 y 3d model (jsmol) interactive image 3dmet b00334 beilstein reference 1697256 chebi chebi:18127 y chembl chembl119296 y chemspider 13866593 y drugbank db03854 y echa infocard 100.006.664 ec number 207-329-0 gmelin reference 2310 kegg c01672 y mesh cadaverine pubchem cid 273 rtecs number sa0200000 unii l90ben6oll y un number 2735 comptox dashboard (epa) dtxsid5075448 inchi inchi=1s/c5h14n2/c6-4-2-1-3-5-7/h1-7h2 ykey: vhrgrcvqafmjiz-uhfffaoysa-n y smiles ncccccn properties chemical formula c5h14n2 molar mass 102.181 g·mol−1 appearance colourless liquid odor unpleasant density 873,0 g/l melting point 11.83 °c (53.29 °f; 284.98 k) boiling point 179.1 °c; 354.3 °f; 452.2 k solubility in water soluble solubility in other solvents conventional organic solvents log p −0.123 acidity (pka) 10.25, 9.13 refractive index (nd) 1.458 hazards ghs labelling: pictograms signal word danger hazard statements h314 precautionary statements p280, p305+p351+p338, p310 nfpa 704 (fire diamond) 3 2 0 flash point 62 °c (144 °f; 335 k) lethal dose or concentration (ld, lc): ld50 (median dose) 2000 mg/kg (oral, rat) related compounds related alkanamines n-butylamineputrescinepentylaminehexamethylenediamine except where otherwise noted, data are given for materials in their standard state (at 25 °c , 100 kpa). y verify (what is yn ?) infobox references production cadaverine is produced by decarboxylation of lysine. it can be synthesized by many methods including the hydrogenation of glutaronitrile and the reactions of 1,5-dichloropentane. history putrescine and cadaverine were first described in 1885 by the berlin physician ludwig brieger (1849–1919). receptors in zebrafish, the trace amine-associated receptor 13c (or taar13c) has been identified as a high-affinity receptor for cadaverine. in humans, molecular modelling and docking experiments have shown that cadaverine fits into the binding pocket of the human taar6 and taar8. clinical significance elevated levels of cadaverine have been found in the urine of some patients with defects in lysine metabolism. the odor commonly associated with bacterial vaginosis has been linked to cadaverine and putrescine. derivatives pentolinium and pentamethonium. toxicity acute oral toxicity of cadaverine is 2,000 mg/kg body weight; its no-observed-adverse-effect level is 2,000 ppm (180 mg/kg body weight/day).