parahexyl parahexyl parahexyl (synhexyl, n-hexyl-δ3-thc, (c6)-δ6a(10a)-thc) is a synthetic homologue of thc which was invented in 1941 during attempts to elucidate the structure of δ9-thc, one of the active components of cannabis. parahexylclinical dataatc codenonelegal statuslegal status ca: schedule ii de: anlage i (authorized scientific use only) uk: class b us: schedule i un: psychotropic schedule i identifiers iupac name 3-n-hexyl- 7,8,9,10-tetrahydro- 6,6,9-trimethyl- 6h-dibenzo(b,d)pyran- 1-ol cas number117-51-1 ypubchem cid8334chemspider8031 yunii450n174f9wchemical and physical dataformulac22h32o2molar mass328.496 g·mol−13d model (jsmol)interactive image smiles oc2cc(cc1oc(c\3=c(/c12)cc(cc/3)c)(c)c)cccccc inchi inchi=1s/c22h32o2/c1-5-6-7-8-9-16-13-19(23)21-17-12-15(2)10-11-18(17)22(3,4)24-20(21)14-16/h13-15,23h,5-12h2,1-4h3 ykey:oorfxdswecaqli-uhfffaoysa-n y (verify) parahexyl is similar in both structure and activity to thc, differing only in the position of one double bond and the lengthening of the 3-pentyl chain by one ch2 group to n-hexyl. parahexyl produces effects typical of other cannabinoid receptor agonists in animals. it has a somewhat higher oral bioavailability than thc itself but is otherwise very similar. presumably, it acts as a cb1 agonist in the same way as thc, but as there has been no research published using parahexyl since the discovery of the cb1 receptor, this has not been definitively confirmed. parahexyl was occasionally used as an anxiolytic in the mid-20th century, the dosage ranging from 5 mg to 90 mg. parahexyl was made illegal under un convention in 1982 on the basis of its structural similarity and similar effects profile to thc. parahexyl was placed into the most restrictive schedule 1 as a compound with no medical use, despite the now-known medical uses for cannabinoids. isomerism at least three isomers of parahexyl have been studied and are known to be active as cannabinoids. parahexyl itself (i.e. the δ6a(10a) isomer) has not had any significant use in scientific research since it was banned internationally in the early 1980s; however, the δ8 and δ9 isomers are both known to be cannabinoid receptor agonists, and δ8-parahexyl has the code number jwh-124, while δ9-parahexyl has been isolated from cannabis plant material and assigned the name tetrahydrocannabihexol. dibenzopyran and monoterpenoid numbering of tetrahydrocannabinol derivatives 7 double bond isomers of parahexyl and their 30 stereoisomers dibenzopyran numberingmonoterpenoid numberingnumber of stereoisomersnatural occurrenceconvention on psychotropic substances schedule short namechiral centersfull nameshort namechiral centers δ6a(7)-parahexyl9 and 10a3-hexyl-8,9,10,10a-tetrahydro-6,6,9-trimethyl-6h-dibenzopyran-1-olδ4-parahexyl1 and 34nounscheduled δ7-parahexyl6a, 9 and 10a3-hexyl-6a,9,10,10a-tetrahydro-6,6,9-trimethyl-6h-dibenzopyran-1-olδ5-parahexyl1, 3 and 48nounscheduled δ8-parahexyl6a and 10a3-hexyl-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6h-dibenzopyran-1-olδ6-parahexyl3 and 44nounscheduled δ9,11-parahexyl6a and 10a3-hexyl-6a,7,8,9,10,10a-hexahydro-6,6-dimethyl-9-methylene-6h-dibenzopyran-1-olδ1(7)-parahexyl3 and 44nounscheduled δ9-parahexyl6a and 10a3-hexyl-6a,7,8,10a-tetrahydro-6,6,9-trimethyl-6h-dibenzopyran-1-olδ1-parahexyl3 and 44nounscheduled δ10-parahexyl6a and 93-hexyl-6a,7,8,9-tetrahydro-6,6,9-trimethyl-6h-dibenzopyran-1-olδ2-parahexyl1 and 44nounscheduled δ6a(10a)-parahexyl93-hexyl-7,8,9,10-tetrahydro-6,6,9-trimethyl-6h-dibenzopyran-1-olδ3-parahexyl12noschedule i note that 6h-dibenzopyran-1-ol is the same as 6h-benzochromen-1-ol.