ditolylguanidine ditolylguanidine ditolylguanidine is a sigma receptor agonist. it is somewhat selective for sigma receptors, but non-selective between the two sigma receptor subtypes, binding to both σ1 and σ2 with equal affinity. it has neuroprotective and antidepressant effects, and potentiates the effects of nmda antagonists. ditolylguanidineclinical dataatc codenoneidentifiers iupac name 1,2-bis(2-methylphenyl)guanidine cas number97-39-2 ypubchem cid7333iuphar/bps6684chemspider7056 yuniill2p01i17ochemblchembl282433 ycomptox dashboard (epa)dtxsid2026606 echa infocard100.002.344 chemical and physical dataformulac15h17n3molar mass239.322 g·mol−13d model (jsmol)interactive image smiles n(=c(/nc1ccccc1c)n)\c2ccccc2c inchi inchi=1s/c15h17n3/c1-11-7-3-5-9-13(11)17-15(16)18-14-10-6-4-8-12(14)2/h3-10h,1-2h3,(h3,16,17,18) ykey:opnurokcubtklf-uhfffaoysa-n y (verify)