extracranial germ cell tumor extracranial germ cell tumor an extracranial germ cell tumor (egct) occurs in the abnormal growth of germ cells in the gonads (testes or ovaries) and the areas other than the brain via tissue, lymphatic system, or circulatory system. the tumor can be benign or malignant (cancerous) by its growth rate. according to the national cancer institute and st. jude children's research hospital, the chance of children who are under 15 years old having egcts is 3%, in comparison to adolescents, a possibility of 14% with aged 15 to 19 can have egcts. there is no obvious cut point in between children and adolescents. however, common cut points in researches are 11 years old and 15 years old. extracranial germ cell tumora mixed germ cell tumorspecialtyoncologysymptomspainless bump in the center of body, abnormal menstruation, bump in testesrisk factorsspecific genetic syndrome, congenital abnormalitiesdiagnostic methodtumor marker test, immunohistochemistry, mri, chest x-ray, ct scan, ultrasound exam, biopsytreatmentsurgery, chemotherapy, radiotherapymedicationcisplatin based chemotherapy, bep (cisplatin, etoposide, and bleomycin)prognosishigh survival rate after treatmentsfrequency3%(<15) and 14%(≥15) the signs and symptoms are varied according to the location of the egcts. common symptoms are fever, constipation, abdomen mass with or without pain, backache, bumps in testicles for male, abnormal bleeding in vagina or miss menses for female. the cause of egcts has not been found. some potential risk factors include smoking, alcohol consumption, specific genetic syndromes, congenital abnormalities, and more. among these risk factors, specifically, the klinefelter syndrome (ks) and cryptorchidism increase the possibility for males having testicular tumors and the turner syndrome (ts) affects the risk of having ovarian cysts in females. swyer syndrome and other syndromes may increase the risk of having egcts in the gonads. the diagnosis is made by a combination of picture-taking testaments, physical examinations, and the investigation of samples from blood, urine, and tissue by using microscope. by collecting the data from the testaments, clinicians use the classifications of egcts to assist diagnosing the type of tumor. due to the probability of having egcts among pediatric, several treatments had been used to remove the tumor or kill the cancer cells. the treatments include surgery, chemotherapy, radiation therapy, targeted therapy, salvage therapy, and clinical trials. among the treatments, the bep combination (bleomycin, etoposide, cisplatin) is the standard chemotherapy treatment method for egcts by increasing the survival rate. the prognosis of egcts are varied after a series of treatments and follow-up testaments which include factors of age, gender, type of egct, location the cyst, treatment method, response, and symptoms are presented after a period of time. signs and symptoms signs and symptoms of extracranial germ cell tumor can be seen in children, adolescents, or young adults. these symptoms include fever, constipation, abnormal bleeding in vagina and miss menstruation in females, a lump in the testes in males, lumps along the midline of the body, include coccyx, neck, and abdomen. the symptoms of egcts appear differently by the location of it. according to the symptoms and location of the egcts, specialists may diagnose the type of the tumor. risk factors