choices and family planning modifications. negative results which may potentially be inaccurate, theoretically decrease the quality of life and mental health of the individual (such as increased depression and extensive anxiety). direct-to-consumer genetics there are also three potential problems associated with the validity of personal genome kits. the first issue is the test's validity. handling errors of the sample increases the likelihood for errors which could affect the test results and interpretation. the second affects the clinical validity, which could affect the test's ability to detect or predict associated disorders. the third problem is the clinical utility of personal genome kits and associated risks, and the benefits of introducing them into clinical practices. people need to be educated on interpreting their results and what they should be rationally taking from the experience. concerns about customers misinterpreting health information was one of the reasons for the 2013 shutdown by the fda of 23&me's health analysis services. it is not only the average person who needs to be educated in the dimensions of their own genomic sequence but also professionals, including physicians and science journalists, who must be provided with the knowledge required to inform and educate their patients and the public. examples of such efforts include the personal genetics education project (pged), the smithsonian collaboration with nhgri, and the medseq, babyseq and milseq projects of genomes to people, an initiative of harvard medical school and brigham and women's hospital. a major use of personal genomics outside the realm of health is that of ancestry analysis (see genetic genealogy), including evolutionary origin information such as neanderthal content. popular culture the 1997 science fiction film gattaca presents a near-future society where personal genomics is readily available to anyone, and explores its societal impact. perfect dna is a novel that uses dr manuel corpas' own experiences and expertise as genome scientist to begin exploring some of these tremendously challenging issues. other uses in 2018, police arrested joseph james deangelo, the prime suspect for the golden state killer or east area rapist, and william earl talbott ii, the prime suspect in the murders of jay cook and tanya van cuylenborg in 1987. these arrests were based on the personal genomics uploaded to an open-source database, gedmatch, which allowed investigators to compare dna recovered from crime scenes to the dna uploaded to the database by relatives of the suspect. in december 2018, familytreedna changed its terms of service to allow law enforcement to use their service to identify suspects of "a violent crime" or identify the remains of victims. the company confirmed it was working with the fbi on at least a handful of cases. since then, nearly 50 suspects in crimes of assault, rape or murder have been arrested using the same method. personal genomics have also allowed investigators to identify previously unknown bodies using gedmatch (the buckskin girl, lyle stevik and joseph newton chandler iii).