list of cutaneous conditions caused by problems with junctional proteins list of cutaneous conditions caused by problems with junctional proteins mutations of proteins that hold the cells of the skin together can cause disease. autoantibodies against proteins that hold the cells of the skin together can also cause disease. conditions caused by mutations in or antibodies against junctional proteins found within the epidermis of the human integumentary system. junctional proteincondition(s) desmocollin 1subcorneal pustular dermatosis type of iga pemphigus desmocollin 2arrhythmogenic right ventricular dysplasia (arvd) desmoglein 1striate palmoplantar keratodermapemphigus foliaceousbullous impetigostaphylococcal scalded skin syndromefogo selvagempemphigus erythematosusmucocutaneous pemphigus vulgaris desmoglein 2arvd desmoglein 3mucosal pemphigus vulgarispemphigus vegetans mucocutaneous pemphigus vulgaris desmoglein 4localized autosomal recessive hypotrichosisautosomal recessive monilethrix desmoplakinstriate palmoplantar keratodermacarvajal syndromeskin fragility–wooly hair syndromelethal acantholytic epidermolysis bullosaarvdparaneoplastic pemphigusstevens–johnson syndrome plakoglobinnaxos diseasestriate palmoplantar keratodermaarvd plakophilin 1ectodermal dysplasia–skin fragility syndrome plakophilin 2arvd corneodesmosinhypertrichosis simplex of the scalp