katz syndrome katz syndrome katz syndrome is a rare congenital disorder, presenting as a polymalformative syndrome characterized by enlarged viscera, hepatomegaly, diabetes, and skeletal anomalies that result in a short stature, cranial hyperostosis, and typical facial features. it is probably a variant of the autosomal recessive type of craniometaphyseal dysplasia. katz syndromeother nameshyperostosis frontalis internahyperostosis frontalis interna in a 74-year-old womanspecialtymedical genetics symptoms and signs manifestations include enlarged viscera, hepatomegaly, diabetes, short stature and cranial hyperostosis. diagnosis