evodiamine evodiamine evodiamine is a chemical compound extracted from the plant genus tetradium, which has been shown to reduce fat uptake in mouse studies. it is suspected that its mechanism of action is similar to that of capsaicin. as such, it has been included in some dietary supplements. neither its fat-burning effects in humans nor any potential side effects have been empirically established. evodiamineclinical dataatc codenoneidentifiers iupac name 21-methyl-3,13,21-triazapentacyclohenicosa-2(10),4,6,8,15,17,19-heptaen-14-one cas number518-17-2 ypubchem cid442088chemspider133343 yuniic01825bvnlchemblchembl486598 ncomptox dashboard (epa)dtxsid10966123 echa infocard100.164.846 chemical and physical dataformulac19h17n3omolar mass303.365 g·mol−13d model (jsmol)interactive image smiles o=c4n3ccc2c(c1ccccc12)c3n(c5ccccc45)c inchi inchi=1s/c19h17n3o/c1-21-16-9-5-3-7-14(16)19(23)22-11-10-13-12-6-2-4-8-15(12)20-17(13)18(21)22/h2-9,18,20h,10-11h2,1h3 ykey:txduthbfykgsah-uhfffaoysa-n y ny (what is this?) (verify) evodiamine acts primarily as a thermogenic and stimulant. evodiamine may also act by increasing the number of serotonin transporters available in the brain, enhancing the reuptake of serotonin.