bibp-3226 bibp-3226 bibp-3226 is a drug used in scientific research which acts as a potent and selective antagonist for both the neuropeptide y receptor y1 and also the neuropeptide ff receptor. it was the first non-peptide antagonist developed for the y1 receptor and has been widely used to help determine its functions in the body. activation of y1 is thought to be involved in functions such as regulation of appetite and anxiety, and bibp-3226 has anxiogenic and anorectic effects, as well as blocking the y1-mediated corticotropin releasing hormone release. it has also been used as a lead compound to develop a number of newer more potent y1 antagonists. bibp-3226clinical dataother namesbibp-3226identifiers iupac name (2r)-5-(diaminomethylideneamino)-2-(amino)-n-pentanamide cas number159013-54-4 npubchem cid5311023iuphar/bps1485chemspider4470561 ychemblchembl332347 ycomptox dashboard (epa)dtxsid30415502 chemical and physical dataformulac27h31n5o3molar mass473.577 g·mol−13d model (jsmol)interactive image smiles c1=cc=c(c=c1)c(c2=cc=cc=c2)c(=o)n(cccn=c(n)n)c(=o)ncc3=cc=c(c=c3)o inchi inchi=1s/c27h31n5o3/c28-27(29)30-17-7-12-23(25(34)31-18-19-13-15-22(33)16-14-19)32-26(35)24(20-8-3-1-4-9-20)21-10-5-2-6-11-21/h1-6,8-11,13-16,23-24,33h,7,12,17-18h2,(h,31,34)(h,32,35)(h4,28,29,30)/t23-/m1/s1 ykey:kuwbxrgrmqzcss-hszrjfapsa-n y ny (what is this?) (verify)