solpadeine solpadeine solpadeine is the brand name of a range of analgesic medication containing various amounts of paracetamol, ibuprofen, caffeine and codeine, made by omega pharma. the range was previously made by glaxosmithkline, which sold its portfolio of over-the-counter drugs to omega pharma in 2012. 1998 advertisement in the united kingdom there are four different medicines using the solpadeine name, with no common active ingredient between them. the range includes: solpadeine headache, containing paracetamol with caffeine solpadeine plus, a compound analgesic containing paracetamol and codeine (co-codamol), with caffeine solpadeine max, a compound analgesic containing paracetamol and codeine (with a higher codeine content than solpadeine plus) solpadeine migraine, a compound analgesic containing ibuprofen and codeine in 2016 it was one of the biggest selling branded over-the-counter medications sold in great britain, with sales of £43.1 million. in australia it is marketed as panadeine.