ici-204,448 ici-204,448 ici-204,448 is a drug which acts as a potent and peripherally selective κ-opioid agonist, with possible uses in the treatment of heart attack as well as anti-itching effects. it is used in research to distinguish centrally from peripherally mediated kappa opioid receptor effects. ici-204,448identifiers iupac name 2-(3--methylamino)-2-pyrrolidin-1-ylethyl]phenoxy)acetic acid cas number121264-04-8 ypubchem cid3683iuphar/bps1650chemspider3555 nchebichebi:91666 nchemblchembl23472 ncomptox dashboard (epa)dtxsid20923747 chemical and physical dataformulac23h26cl2n2o4molar mass465.37 g·mol−13d model (jsmol)interactive image smiles c2cccn2cc(c(ccc3)cc3occ(o)=o)n(c)c(=o)cc(cc1cl)ccc1cl inchi inchi=1s/c23h26cl2n2o4/c1-26(22(28)12-16-7-8-19(24)20(25)11-16)21(14-27-9-2-3-10-27)17-5-4-6-18(13-17)31-15-23(29)30/h4-8,11,13,21h,2-3,9-10,12,14-15h2,1h3,(h,29,30) nkey:jkyjsfisyhsnoe-uhfffaoysa-n n ny (what is this?) (verify)