keratoderma climactericum keratoderma climactericum keratoderma climactericum is a skin condition characterized by hyperkeratosis of the palms and soles beginning at about the time of menopause.: 213 keratoderma climactericumother namesclimacteric keratoderma, haxthausen's disease, and acquired plantar keratoderma,specialtydermatology causes keratoderma climactericum is either inherited through an abnormal gene, or it is acquired through a change in the health or environment of the individual.