cloroqualone cloroqualone cloroqualone is a quinazolinone-class gabaergic and is an analogue of methaqualone developed in the 1980s and marketed mainly in france and some other european countries. it has sedative and antitussive properties resulting from its agonist activity at the β subtype of the gabaa receptor and sigma-1 receptor, and was sold either alone or in combination with other ingredients as a cough medicine. cloroqualone has weaker sedative properties than methaqualone and was sold for its useful cough-suppressing effects, but was withdrawn from the french market in 1994 because of concerns about its potential for abuse and overdose. cloroqualoneclinical datapregnancycategory ? routes ofadministration?atc codenonepharmacokinetic databioavailability?metabolism?elimination half-life?excretion?identifiers iupac name 3-(2,6-dichlorophenyl)-2-ethyl-4-quinazolinone cas number25509-07-3 npubchem cid63338drugbank? nchemspider57005 yunii172d4q6lowchemblchembl2106114 ncomptox dashboard (epa)dtxsid10180201 echa infocard100.042.761 chemical and physical dataformulac16h12cl2n2omolar mass319.185 g·mol−13d model (jsmol)interactive image smiles clc3cccc(cl)c3n/1c(=o)c2c(\n=c\1cc)cccc2 inchi inchi=1s/c16h12cl2n2o/c1-2-14-19-13-9-4-3-6-10(13)16(21)20(14)15-11(17)7-5-8-12(15)18/h3-9h,2h2,1h3 ykey:sonhvlidlxlsol-uhfffaoysa-n y ny (what is this?) (verify)