megazol megazol megazol (cl 64855) is a nitroimidazole based drug that cures some protozoan infections. megazolclinical dataatc codenoneidentifiers iupac name 5-(1-methyl-5-nitro-1h-imidazol-2-yl)-1,3,4-thiadiazol-2-amine cas number19622-55-0 ychemspider27598uniivq8uh664zjcomptox dashboard (epa)dtxsid50173298 chemical and physical dataformulac6h6n6o2smolar mass226.21 g·mol−13d model (jsmol)interactive image smiles cn1c(cnc1c2nnc(s2)n)(=o) a study of nitroimidazoles found the drug extremely effective against t. cruzi and t. brucei which cause chagas disease and african sleeping sickness, respectively. the drug is considerably more effective than standard benznidazole therapy (for chagas) which is considered the gold standard. this is despite that other nitroimidazoles proved ineffective against these pathogens.