beta1-adrenergic agonist beta1-adrenergic agonist beta1-adrenergic agonists, also known as beta1-adrenergic receptor agonists, are a class of drugs that bind selectively to the beta-1 adrenergic receptor. as a result, they act more selectively upon the heart. beta-adrenoceptors typically bind to norepinephrine release by sympathetic adrenergic nerves and to circulating epinephrine. the effect of b-adrenoceptors is cardiac stimulation, such as increased heart rate, heart contractility, heart conduction velocity and heart relaxation. examples examples include: denopamine β1 agonist dobutamine β1>β2 agonist xamoterol β1 partial agonist epinephrine epinephrine is a non-selective beta agonist, this means it also stimulates the beta 2 adrenergic receptor. therefore, epinephrine is a beta2-adrenergic agonist. isoprenaline