non-communicable disease non-communicable disease a non-communicable disease (ncd) is a disease that is not transmissible directly from one person to another. ncds include parkinson's disease, autoimmune diseases, strokes, most heart diseases, most cancers, diabetes, chronic kidney disease, osteoarthritis, osteoporosis, alzheimer's disease, cataracts, and others. ncds may be chronic or acute. most are non-infectious, although there are some non-communicable infectious diseases, such as parasitic diseases in which the parasite's life cycle does not include direct host-to-host transmission. non-communicable diseasea nurse with a non-communicable diseases kit, fiji, 2012. ncds are the leading cause of death globally. in 2012, they caused 68% of all deaths (38 million) up from 60% in 2000. about half were under age 70 and half were women. risk factors such as a person's background, lifestyle and environment increase the likelihood of certain ncds. every year, at least 5 million people die because of tobacco use and about 2.8 million die from being overweight. high cholesterol accounts for roughly 2.6 million deaths and 7.5 million die because of high blood pressure. risk factors risk factors such as a person's background; lifestyle and environment are known to increase the likelihood of certain non-communicable diseases. they include age, gender, genetics, exposure to air pollution, and behaviors such as smoking, unhealthy diet and physical inactivity which can lead to hypertension and obesity, in turn leading to increased risk of many ncds. most ncds are considered preventable because they are caused by modifiable risk factors. the who's world health report 2002 identified five important risk factors for non-communicable disease in the top ten leading risks to health. these are raised blood pressure, raised cholesterol, tobacco use, alcohol consumption, and being overweight. the other factors associated with higher risk of ncds include a person's economic and social conditions, also known as the social determinants of health. it has been estimated that if the primary risk factors were eliminated, 80% of the cases of heart disease, stroke and type 2 diabetes and 40% of cancers could be prevented. interventions targeting the main risk factors could have a significant impact on reducing the burden of disease worldwide. efforts focused on better diet and increased physical activity have been shown to control the prevalence of ncds . environmental diseases ncds include many environmental diseases covering a broad category of avoidable and unavoidable human health conditions caused by external factors, such as sunlight, nutrition, pollution, and lifestyle choices. the diseases of affluence are non-infectious diseases with environmental causes. examples include: many types of cardiovascular disease (cvd) chronic obstructive pulmonary disease (copd) caused by smoking tobacco diabetes mellitus type 2 noise-induced hearing loss lower back pain caused by too little exercise malnutrition caused by too little food, or eating the wrong kinds of food (e.g. scurvy from lack of vitamin c) skin cancer caused by radiation from the sun obesity inherited diseases