(mean 12.7). a similar n=5 study by davies et al. (1977) found a narrower range of half-lives, between 6.7 - 13 hours (average 8.6 hours), while an n=8 study by keraäen et al. that included younger patients found a somewhat shorter average half-life of 7.5 hours. history clonidine was introduced in 1966. it was first used as a hypertension treatment under the trade name of catapres. society and culture brand names as of june 2017, clonidine was marketed under many brand names worldwide: arkamin, aruclonin, atensina, catapin, catapres, catapresan, catapressan, chianda, chlofazoline, chlophazolin, clonid-ophtal, clonidin, clonidina, clonidinã, clonidine, clonidine hydrochloride, clonidinhydrochlorid, clonidini, clonidinum, clonigen, clonistada, clonnirit, clophelinum, dixarit, duraclon, edolglau, haemiton, hypodine, hypolax, iporel, isoglaucon, jenloga, kapvay, klofelino, kochaniin, lonid, melzin, menograine, normopresan, paracefan, pinsanidine, run rui, and winpress. it was marketed as a combination drug with chlortalidone as arkamin-h, bemplas, catapres-diu, and clorpres, and in combination with bendroflumethiazide as pertenso.