1,4-dihydropyridine 1,4-dihydropyridine 1,4-dihydropyridine (dhp) is an organic compound with the formula ch2(ch=ch)2nh. the parent compound is uncommon, but derivatives of 1,4-dihydropyridine are important commercially and biologically. the pervasive cofactors nadh and nadph are derivatives of 1,4-dihydropyridine. 1,4-dihydropyridine-based drugs are l-type calcium channel blockers, used in the treatment of hypertension. 1,2-dihydropyridines are also known. 1,4-dihydropyridine names preferred iupac name 1,4-dihydropyridine identifiers cas number 3337-17-5 y 3d model (jsmol) interactive image chemspider 94619 y mesh 1,4-dihydropyridine pubchem cid 104822 unii 7m8k3p6i89 y comptox dashboard (epa) dtxsid20274185 inchi inchi=1s/c5h7n/c1-2-4-6-5-3-1/h2-6h,1h2 ykey: yngdwrxwkfwcjy-uhfffaoysa-n y smiles c1c=cnc=c1 properties chemical formula c5h7n molar mass 81.1158 g mol−1 except where otherwise noted, data are given for materials in their standard state (at 25 °c , 100 kpa). y verify (what is yn ?) infobox references properties and reactions a recurring feature of 1,4-dihydropyridines is the presence of substituents at the 2- and 6-positions. dihydropyridines are enamines, which otherwise tend to tautomerize or hydrolyze. the dominant reaction of dihydropyridines is their ease of oxidation. in the case of dihydropyridines with hydrogen as the substituent on nitrogen, oxidation yields pyridines: ch2(ch=cr)2nh → c5h3r2n + h2 the naturally-occurring dihydropyridines nadh and nadph contain n-alkyl groups. therefore, their oxidation does not yield pyridine, but n-alkylpyridinium cations: ch2(ch=cr)2nr' → c5h3r2nr' + h−