blepharochalasis blepharochalasis blepharochalasis is an inflammation of the eyelid that is characterized by exacerbations and remissions of eyelid edema, which results in a stretching and subsequent atrophy of the eyelid tissue, leading to the formation of redundant folds over the lid margins. it typically affects only the upper eyelids, and may be unilateral as well as bilateral. blepharochalasisspecialtydermatology signs and symptoms complications complications of blepharochalasis may include conjunctival hyperemia (excessive blood flow through the moist tissues of the orbit), chemosis, entropion, ectropion, and ptosis. causes blepharochalasis is idiopathic in most cases, i.e., the cause is unknown. systemic conditions linked to blepharochalasis are renal agenesis, vertebral abnormalities, and congenital heart disease. pathophysiology blepharochalasis results from recurrent bouts of painless eyelid swelling, each lasting for several days. this is thought to be a form of localized angioedema, or rapid accumulation of fluid in the tissues. recurrent episodes lead to thin and atrophic skin. damage to the levator palpebrae superioris muscle causes ptosis, or drooping of the eyelid, when the muscle can no longer hold the eyelid up. diagnosis differential diagnosis dermatochalasis is sometimes confused with blepharochalasis, but these are two different conditions. treatment the following procedures have been described for blepharochalasis: external levator aponeurosis tuck blepharoplasty lateral canthoplasty dermis fat grafts these are used to correct atrophic blepharochalasis after the syndrome has run its course. epidemiology it is encountered more commonly in younger rather than older individuals