uh-301 uh-301 (s)-uh-301 is a drug and research chemical widely used in scientific studies. it acts as a selective 5-ht1a receptor silent antagonist. it is structurally related to 8-oh-dpat. uh-301 was found to produce a head-twitch response in mice which is usually typical of 5-ht2a agonist drugs, and has subsequently been used to investigate how 5-ht1a receptor activity modulates 5-ht2a receptors downstream. uh-301identifiers iupac name (s)-5-fluoro-8-hydroxy-2-(dipropylamino)tetralin cas number127126-22-1 yiuphar/bps61unii1t7773jh5ncomptox dashboard (epa)dtxsid70155410 chemical and physical dataformulac16h24fnomolar mass265.372 g·mol−13d model (jsmol)interactive image smiles c2cc1c(c(o)ccc1f)cc2n(ccc)ccc (verify)