5-meo-dalt 5-meo-dalt 5-meo-dalt or n,n-di allyl-5-methoxy tryptamine is a psychedelic tryptamine first synthesized by alexander shulgin. 5-meo-daltlegal statuslegal status de: npsg (industrial and scientific use only) uk: class a illegal in china, japan, singapore, sweden, florida and louisiana identifiers iupac name n--n-(prop-2-en-1-yl)prop-2-en-1-amine cas number928822-98-4 ypubchem cid50878551chemspider21106245 yuniiv25vk0qtaachemblchembl2391541comptox dashboard (epa)dtxsid30239169 chemical and physical dataformulac17h22n2omolar mass270.376 g·mol−13d model (jsmol)interactive image smiles c=ccn(ccc1=cnc2=c1c=c(oc)c=c2)cc=c inchi inchi=1s/c17h22n2o/c1-4-9-19(10-5-2)11-8-14-13-18-17-7-6-15(20-3)12-16(14)17/h4-7,12-13,18h,1-2,8-11h2,3h3 ykey:hgrhweauhxynnp-uhfffaoysa-n y ny (what is this?) (verify) chemistry the full name of the chemical is n-allyl-n- prop-2-en-1- amine. it is related to the compounds 5-meo-dpt and dalt. in april 2020, chadeayne et al. solved the crystal structure of the freebase form of 5-meo-dalt. pharmacology 5-meo-dalt binds to 5-ht1a, 5-ht1d, 5-ht1e, 5-ht2a, 5-ht2b, 5-ht2c, 5-ht6, α2a, α2b, α2c, h1, κ-opioid, σ1 and σ2 receptors with ki values lower than 10μm and also acts as a dat and sert monoamine reuptake inhibitor. binding site pki ± sem at binding site 5-ht1a7.70 ± 0.10 5-ht1b6.13 ± 0.04 5-ht1d7.00 ± 0.10 5-ht1e6.30 ± 0.05 5-ht2a6.66 ± 0.08 5-ht2b7.23 ± 0.05 5-ht2c6.34 ± 0.08 5-ht5a5.48 ± 0.04 5-ht66.81 ± 0.03 5-ht77.05 ± 0.07 α2a6.67 ± 0.07 α2b6.14 ± 0.04 α2c5.83 ± 0.06 h16.30 ± 0.06 h35.77 ± 0.04 κor5.95 ± 0.07 μor< 5.00 σ16.52 ± 0.06 σ26.60 ± 0.05 dat5.50 ± 0.20 net< 5.00 sert6.30 ± 0.05 the metabolism and cytochrome p450 inhibition of 5-meo-dalt has been described in scientific literature. history the first material regarding the synthesis and effects of 5-meo-dalt was sent from alexander shulgin to a research associate named murple in may 2004, after which it was circulated online. in june 2004 5-meo-dalt became available from internet research chemical vendors after being synthesized by commercial laboratories in china. in august 2004 the synthesis and effects of 5-meo-dalt were published by erowid. dosage doses ranging from 12–20 mg were tested by alexander shulgin's research group. therapeutic use numerous anecdotal reports and a small-scale trial indicate the potential of 5-meo-dalt for the treatment of cluster headache, one of the most excruciating conditions known to medicine. these observations are consistent with evidence of efficacy of other chemically-related indoleamines in the treatment of cluster headache. side effects there is no published literature on the toxicity of 5-meo-dalt. legal status china as of october 2015 5-meo-dalt is a controlled substance in china. japan 5-meo-dalt became a controlled substance in japan from april 2007, by amendment to the pharmaceutical affairs law. united kingdom 5-meo-dalt became a class a drug in the uk on january 7, 2015 after an update to the tryptamine blanket ban. singapore 5-meo-dalt is listed in the fifth schedule of the misuse of drugs act (mda) and therefore illegal in singapore as of may 2015. sweden sveriges riksdag added 5-meo-dalt to schedule i ("substances, plant materials and fungi which normally do not have medical use") as narcotics in sweden as of may 1, 2012, published by medical products agency in their regulation lvfs 2012:6 listed as 5-meo-dalt n-allyl-n--prop-2-en-1-amin. united states 5-meo-dalt is not scheduled at the federal level in the united states, but it is likely that it could be considered an analog of 5-meo-dipt, which is a controlled substance in usa, or an analog of another tryptamine, in which case purchase, sale, or possession could be prosecuted under the federal analog act. florida 5-meo-dalt is a schedule i controlled substance in the state of florida making it illegal to buy, sell, or possess in florida. louisiana 5-meo-dalt is a schedule i controlled substance in the state of louisiana making it illegal to buy, sell, or possess in louisiana. notes chadeayne ar, pham dn, golen ja, manke dr (april 2020). "5-meo-dalt: the freebase of n,n-diallyl-5-meth-oxy-tryptamine". iucrdata. international union of crystallography (iucr). 5 (pt 4): x200498. doi:10.1107/s2414314620004988. pmc 9462216. pmid 36338299. cozzi nv, daley pf (february 2016). "receptor binding profiles and quantitative structure-affinity relationships of some 5-substituted-n,n-diallyltryptamines". bioorganic & medicinal chemistry letters. elsevier bv. 26 (3): 959–964. doi:10.1016/j.bmcl.2015.12.053. pmid 26739781. michely ja, helfer ag, brandt sd, meyer mr, maurer hh (october 2015). "metabolism of the new psychoactive substances n,n-diallyltryptamine (dalt) and 5-methoxy-dalt and their detectability in urine by gc-ms, lc-msn, and lc-hr-ms-ms" (pdf). analytical and bioanalytical chemistry. springer science and business media llc. 407 (25): 7831–7842. doi:10.1007/s00216-015-8955-0. pmid 26297461. s2cid 26086597. dinger j, woods c, brandt sd, meyer mr, maurer hh (january 2016). 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