difluoropine difluoropine difluoropine (o-620) is a stimulant drug synthesised from tropinone, which acts as a potent and selective dopamine reuptake inhibitor. difluoropine is unique among the tropane-derived dopamine reuptake inhibitors in that the active stereoisomer is the (s) enantiomer rather than the (r) enantiomer, the opposite way round compared to natural cocaine. it is structurally related to benztropine and has similar anticholinergic and antihistamine effects in addition to its dopamine reuptake inhibitory action. difluoropineclinical dataother names(s)-(+)-2β-carbomethoxy-3α-(bis(4-fluorophenyl)methoxy)tropaneatc codenoneidentifiers iupac name methyl (1s,2s,3s,5r)-3--8-methyl-8-azabicyclooctane-2-carboxylate cas number156774-35-5pubchem cid190851chemspider165751chemblchembl1945126comptox dashboard (epa)dtxsid20935527 chemical and physical dataformulac23h25f2no3molar mass401.448 g·mol−13d model (jsmol)interactive image smiles cn12cc1((c2)oc(c3=cc=c(c=c3)f)c4=cc=c(c=c4)f)c(=o)oc inchi inchi=1s/c23h25f2no3/c1-26-18-11-12-19(26)21(23(27)28-2)20(13-18)29-22(14-3-7-16(24)8-4-14)15-5-9-17(25)10-6-15/h3-10,18-22h,11-13h2,1-2h3/t18-,19+,20+,21+/m1/s1key:xsygbvsqkpletj-anultfpqsa-n (verify) difluoropine has some stimulant effects in animals, although it is significantly less powerful than many of the potent phenyltropane derived stimulant drugs such as win 35,428 and rti-55. it showed promising effects in alleviating the symptoms of parkinson's disease in an animal model of the disorder. it is not explicitly illegal anywhere in the world as of 2008, but might be considered to be a controlled substance analogue of cocaine on the grounds of its related chemical structure, in some jurisdictions such as the united states, canada, australia and new zealand.