pachydermatous eosinophilic dermatitis pachydermatous eosinophilic dermatitis pachydermatous eosinophilic dermatitis is a skin condition observed in south african black teenage girls and characterized by generalized pruritic papules, hypertrophic genital lesions and peripheral eosinophilia. pachydermatous eosinophilic dermatitisspecialtydermatology