fumarranol fumarranol fumarranol is a drug which acts as an inhibitor of the type 2 methionine aminopeptidase enzyme metap2. it was derived by structural modification of the natural product fumagillin. it was originally developed as an anti-angiogenesis drug for the treatment of cancer, but it was subsequently found to bind with high affinity to the metap2 enzyme in malaria parasites and has been investigated as a potential treatment for malaria. fumarranolidentifiers iupac name (1s,5s)-5-(hydroxymethyl)-1-methoxy-6-bicyclohexan-2-one cas number912569-37-0pubchem cid44416119chemical and physical dataformulac16h24o4molar mass280.364 g·mol−13d model (jsmol)interactive image smiles cc(=cc1(o1)(c)c23(2(c(=o)cc3)oc)co)c inchi inchi=1s/c16h24o4/c1-10(2)5-6-12-14(3,20-12)13-15(9-17)8-7-11(18)16(13,15)19-4/h5,12-13,17h,6-9h2,1-4h3/t12-,13?,14+,15-,16+/m1/s1key:canzhcrplgnwcr-lminuhaasa-n