fosaprepitant fosaprepitant fosaprepitant (emend for injection (us), ivemend (eu)) is an antiemetic medication, administered intravenously. it is a prodrug of aprepitant. fosaprepitantclinical datatrade namesemend, ivemendahfs/drugs.comprofessional drug factsmedlineplusa604003license data eu ema: by inn us dailymed: fosaprepitant us fda: fosaprepitant pregnancycategory au: b2 routes ofadministrationintravenousatc codea04ad12 (who) legal statuslegal status au: s4 (prescription only) uk: pom (prescription only) us: ℞-only eu: rx-only pharmacokinetic databioavailabilityn/aprotein binding>95% (aprepitant)metabolismto aprepitantelimination half-life9 to 13 hours (aprepitant)identifiers iupac name ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl}-5-oxo- 2h-1,2,4-triazol-1-yl]phosphonic acid cas number172673-20-0 y 265121-04-8 (dimeglumine)pubchem cid219090iuphar/bps7623drugbankdb06717 nchemspider189912 nunii6l8of9xrdckeggd06597 nchebichebi:64321 nchemblchembl1199324 nchemical and physical dataformulac23h22f7n4o6pmolar mass614.414 g·mol−13d model (jsmol)interactive image smiles c(c1cc(cc(c1)c(f)(f)f)c(f)(f)f)o2(n(cco2)cc3c(=o)n(n3)p(=o)(o)o)c4ccc(cc4)f inchi inchi=1s/c23h22f7n4o6p/c1-12(14-8-15(22(25,26)27)10-16(9-14)23(28,29)30)40-20-19(13-2-4-17(24)5-3-13)33(6-7-39-20)11-18-31-21(35)34(32-18)41(36,37)38/h2-5,8-10,12,19-20h,6-7,11h2,1h3,(h,31,32,35)(h2,36,37,38)/t12-,19+,20-/m1/s1 nkey:bardrophszebkc-oitmnorjsa-n n ny (what is this?) (verify) fosaprepitant was developed by merck & co. and was approved for medical use in the united states, and in the european union in january 2008.