amelanotic melanoma amelanotic melanoma amelanotic melanoma is a type of skin cancer in which the cells do not make any melanin.: 696 they can be pink, red, purple or of normal skin color, and are therefore difficult to diagnose correctly. they can occur anywhere on the body, just as a typical melanoma can. amelanotic melanomaamelanotic melanoma on dog's toespecialtyoncology, dermatology often, amelanotic melanomas are mistaken for benign lesions, including dermatitis, benign neoplastic processes, or a different malignancy such as basal-cell carcinoma or squamous-cell carcinoma. a poor prognosis is associated with amelanotic lesions, partially due to the difficulty in achieving a diagnosis; however, metastatic amelanotic melanoma has a worse prognosis than other subtypes. survival after diagnosis of amelanotic melanoma was found in a 2014 seven-year study of 3,000 patients to be poorer than for pigmented melanoma, which was attributed to the more advanced stage at diagnosis due probably to difficulty of diagnosis. the study also suggested that amelanotic melanomas might grow faster than pigmented melanomas.