barnidipine barnidipine barnidipine (inn; also known as mepirodipine) is a calcium channel blocker which belongs to the dihydropyridine (dhp) group of calcium channel blockers. it is used in the treatment of hypertension. barnidipineclinical dataahfs/drugs.cominternational drug namesroutes ofadministrationoralatc codec08ca12 (who) identifiers iupac name 3-(3r)-1-benzylpyrrolidin-3-yl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate cas number104713-75-9 npubchem cid443869chemspider391959 nunii2vby96aswjchemblchembl2103761 ncomptox dashboard (epa)dtxsid20909147 chemical and physical dataformulac27h29n3o6molar mass491.544 g·mol−13d model (jsmol)interactive image smiles (=o)c1cccc(c1)4c(/c(=o)oc)=c(\n\c(=c4\c(=o)o3ccn(cc2ccccc2)c3)c)c inchi inchi=1s/c27h29n3o6/c1-17-23(26(31)35-3)25(20-10-7-11-21(14-20)30(33)34)24(18(2)28-17)27(32)36-22-12-13-29(16-22)15-19-8-5-4-6-9-19/h4-11,14,22,25,28h,12-13,15-16h2,1-3h3/t22-,25-/m0/s1 nkey:vxmoonumylcfjd-dhlkqenfsa-n n ny (what is this?) (verify) pharmacodynamics barnidipine is a pure s,s isomer, a lipophilic 1,4-dihydropyridine calcium channel blocker, which, like other compounds in the class, shows a high affinity for calcium channels, particularly the l-type slow channels of smooth muscle cells found in the vessel wall. calcium channel blocking drugs have the characteristic of interfering with the flow of calcium ions into the interior of cells through the slow channels of the plasma membrane.