cloxestradiol cloxestradiol cloxestradiol (inn), also known as 17-(2,2,2-trichloroethoxy)estradiol, is a synthetic, steroidal estrogen which was never marketed. it is an analogue of estradiol with a 2,2,2-trichloroethoxy substitution. the o,o-diacetate derivative, cloxestradiol acetate (brand name genovul), has been marketed as an estrogen. cloxestradiolclinical dataother names17-(2,2,2-trichloroethoxy)estradiol; 17-(1-hydroxy-2,2,2-trichloroethoxy)estra-1,3,5(10-trien-3-oldrug classestrogen; estrogen etheridentifiers iupac name (8r,9s,13s,14s,17s)-13-methyl-17-(2,2,2-trichloro-1-hydroxyethoxy)-6,7,8,9,11,12,14,15,16,17-decahydrocyclopentaphenanthren-3-ol cas number54063-33-1pubchem cid194705chemspider168924unii42r9mzg1dlchemical and physical dataformulac20h25cl3o3molar mass419.77 g·mol−13d model (jsmol)interactive image smiles c12cc3c4ccc(cc4cc31cc2oc(c(cl)(cl)cl)o)o inchi inchi=1s/c20h25cl3o3/c1-19-9-8-14-13-5-3-12(24)10-11(13)2-4-15(14)16(19)6-7-17(19)26-18(25)20(21,22)23/h3,5,10,14-18,24-25h,2,4,6-9h2,1h3/t14-,15-,16+,17+,18?,19+/m1/s1key:jvlhmvxgplklfv-ajuwmhlfsa-n