alisporivir alisporivir alisporivir (inn), or debio 025, deb025, (or unil-025) is a cyclophilin inhibitor. its structure is reminiscent of, and synthesized from ciclosporin. alisporivirclinical dataatc codenoneidentifierscas number254435-95-5 ypubchem cid11513676chemspider9688467 yuniivbp9099aa6keggd10087 nchemblchembl1651956 nniaid chemdb268533echa infocard100.234.903 chemical and physical dataformulac63h113n11o12molar mass1216.662 g·mol−13d model (jsmol)interactive image smiles o=c1n(c(=o)n(c)(c(=o)n(c(=o)n(c(=o)n(c)(c(=o)n(c)(c(=o)n(c)(c(=o)n((c(=o)n(c(=o)n(c)(c(=o)n(cc)1c(c)c)c)cc)(o)(c)c/c=c/c)c)c(c)c)cc(c)c)cc(c)c)c)c)cc(c)c)c(c)c inchi inchi=1s/c63h113n11o12/c1-26-29-30-40(16)52(75)51-56(79)66-44(27-2)59(82)68(20)43(19)58(81)74(28-3)49(38(12)13)55(78)67-48(37(10)11)62(85)69(21)45(31-34(4)5)54(77)64-41(17)53(76)65-42(18)57(80)70(22)46(32-35(6)7)60(83)71(23)47(33-36(8)9)61(84)72(24)50(39(14)15)63(86)73(51)25/h26,29,34-52,75h,27-28,30-33h2,1-25h3,(h,64,77)(h,65,76)(h,66,79)(h,67,78)/b29-26+/t40-,41+,42-,43-,44+,45+,46+,47+,48+,49+,50+,51+,52-/m1/s1 ykey:olrowhgdtnfzbh-xemwpyqtsa-n y ny (what is this?) (verify) it inhibits cyclophilin a. alisporivir is not immunosuppressive. it is being researched for potential use in the treatment of hepatitis c. it has also been investigated for duchenne muscular dystrophy and may have therapeutic potential in alzheimer's disease. alisporivir is under development by debiopharm for japan and by novartis for the rest of the world (licence granted by debiopharm) since february 2010.