list of antiviral drugs list of antiviral drugs antiviral drugs are different from antibiotics. flu antiviral drugs are different than antiviral drugs used to treat other infectious diseases such as covid-19. antiviral drugs prescribed to treat covid-19 are not approved or authorized to treat flu. list of antiviral drugs antiviral use manufacturer component type year approved abacavir hiv nucleoside analogue reverse transcriptase inhibitor (nrti) 1998 acyclovir (aciclovir) herpes simplex, chickenpox, varicella zoster virus guanosine analogue rti 1981 adefovir hepatitis b gilead sciences rti 2002 (fda), 2003 (eu) amantadine influenza influenza a virus m2 proton channel antagonist ampligen avian influenza immunomodulatory double-stranded rna amprenavir (agenerase) hiv protease inhibitor (pi) umifenovir (arbidol) influenza hemagglutinin inhibitor atazanavir hiv pi atripla (efavirenz/emtricitabine/tenofovir) hiv efavirenz: non-nucleoside rti (nnrti) emtricitabine: nrti tenofovir disoproxil: nrti baloxavir marboxil (xofluza) influenza a/b cap snatching endonuclease inhibitor 2018 biktarvy (bictegravir/emtricitabine/tenofovir alafenamide) hiv bictegravir: insti emtricitabine: nrti tenofovir alafenamide: nrti boceprevir hepatitis c genotype 1 schering-plough, then merck group protease inhibitor fda approved 2011 withdrawn 2015 bulevirtide hepatitis d/b sodium/bile acid cotransporter inactivator cidofovir aids viral dna polymerase inhibitor cobicistat (tybost) hiv human cyp3a protein inhibitor combivir (lamivudine/zidovudine) hiv lamivudine: cytidine analogue rti zidovudine: thymidine analogue rti daclatasvir (daklinza) hepatitis c ns5a inhibitor darunavir hiv antiretroviral hiv pi delavirdine hiv antiretroviral nnrti descovy (emtricitabine/tenofovir alafenamide) hepatitis b emtricitabine: nrti tenofovir alafenamide: nrti didanosine hiv adenosine analogue rti docosanol herpes simplex entry inhibitor dolutegravir hiv integrase inhibitor doravirine (pifeltro) hiv nnrti edoxudine herpes simplex thymidine analogue inhibitor efavirenz hiv mylan nnrti 1998 elvitegravir hiv gilead sciences integrase inhibitor 2012 (fixed-dose combo stribild) 2014 (single pill) 2015 (genvoya) emtricitabine hiv gilead sciences nrti 2003 enfuvirtide hiv entry inhibitor 2003 ensitrelvir covid-19 shionogi 3c-like protease inhibitor entecavir hiv nrti 2005 etravirine (intelence) hiv nnrti 2008 famciclovir herpes zoster guanosine analogue 1994 fomivirsen aids anti-sense oligonucleotide anti-sense fda-licensed in 1998 withdrawn in eu (2002), us (2006) fosamprenavir hiv viiv healthcare amprenavir pro-drug 2003 (fda), 2004 (ema) foscarnet herpes pyrophosphate analogue dna polymerase inhibitor 1991 ganciclovir (cytovene) cytomegalovirus (cmv) competitive nucleoside analogue dgtp inhibitor 1988 ibacitabine herpes labialis ibalizumab (trogarzo) hiv entry inhibitor 2018 idoxuridine herpes du analogue inhibitor 1962 imiquimod genital wart, basal cell carcinoma, actinic keratosis opioid growth factor receptor (ogfr) agonist 1997 inosine pranobex herpes simplex thymus hormone immunostimulant indinavir hiv pi 1996 lamivudine hiv cytidine analogue rti letermovir (prevymis) cytomegalovirus (cmv) lopinavir hiv loviride hiv maraviroc hiv entry inhibitor methisazone smallpox moroxydine influenza nelfinavir hiv nirmatrelvir/ritonavir (paxlovid) covid-19 pfizer 3c-like protease inhibitor (nirmatrelvir) / inhibition of metabolism of nirmatrelvir (ritonavir) nevirapine hiv non-nucleoside reverse transcriptase inhibitor nitazoxanide broad-spectrum antiviral thiazolide norvir hiv oseltamivir (tamiflu) influenza neuraminidase inhibitor penciclovir herpes peramivir influenza penciclovir herpes peramivir (rapivab) influenza pleconaril picornavirus schering-plough podophyllotoxin genital wart raltegravir hiv integrase inhibitor remdesivir covid-19 viral rna polymerase inhibitor ribavirin hepatitis c nucleoside analogue reverse transcriptase inhibitor rilpivirine (edurant) hiv rilpivirine hiv rimantadine influenza a m2 proton channel antagonist ritonavir hiv hiv-1 protease inhibitor saquinavir hiv simeprevir (olysio) hepatitis c sofosbuvir hepatitis c nucleoside analogue reverse transcriptase inhibitor stavudine hiv taribavirin (viramidine) hepatitis syndromes in which ribavirin is active telaprevir hepatitis c telbivudine (tyzeka) hepatitis b tenofovir alafenamide hepatitis b tenofovir disoproxil hepatitis b, hiv tipranavir hiv trifluridine eyes related herpes trizivir hiv tromantadine herpes simplex truvada hiv umifenovir influenza valaciclovir (valtrex) herpes simplex/zoster valganciclovir (valcyte) cytomegalovirus (cmv) vicriviroc hiv-1 schering-plough pyrimidine ccr5 entry inhibitor vidarabine herpes simplex, varicella zoster zalcitabine hiv zanamivir (relenza) influenza a, influenza b zidovudine hiv antiretroviral