zygomaticus major muscle zygomaticus major muscle the zygomaticus major muscle is a muscle of the human body. it extends from each zygomatic arch (cheekbone) to the corners of the mouth. it is a muscle of facial expression which draws the angle of the mouth superiorly and posteriorly to allow one to smile. bifid zygomaticus major muscle is a notable variant, and may cause cheek dimples. zygomaticus majormuscles of the head, face, and neck. zygomaticus major shown in red.detailsoriginanterior of zygomaticinsertionmodiolus of the moutharteryfacial arterynervezygomatic and buccal branches of the facial nerveactionsdraws the angle of the mouth upward laterallyidentifierslatinmusculus zygomaticus majorta98a04.1.03.029ta22079fma46810anatomical terms of muscle structure the zygomaticus major muscle originates from the upper margin of the temporal process, part of the lateral surface of the zygomatic bone. it inserts into tissue at the corner of the mouth. nerve supply the zygomaticus major muscle is supplied by a buccal branch and a zygomatic branch of the facial nerve (vii). variation the zygomaticus major muscle may occur in a bifid form, with two fascicles that are partially or completely separate from each other but adjacent. usually a single unit, dimples are caused by variations in form. it is thought that cheek dimples are caused by bifid zygomaticus major muscle. function the zygomaticus major muscle raises the corners of the mouth and draws them posteriorly when a person smiles. the average muscle can contract with a force of 200 g. clinical significance the zygomaticus major muscle may be used in reconstructive surgery to replace lost tissue, such as with injuries to the lips. image position of zygomaticus major muscle. animation. muscles of the head, face, and neck. zygomaticus major shown in red.