minimally invasive adenocarcinoma of the lung minimally invasive adenocarcinoma of the lung minimally invasive adenocarcinoma of the lung (mia) is defined as a small (≤3 cm), solitary tumour with predominant alveolar epithelial appearance (lepidic growth), as in situ adenocarcinoma of the lung, with a zone of focal invasion of the stroma with a size inferior to 5 mm. for mia—as with adenocarcinoma in situ—, the prognosis is near 100% survival. minimally invasive adenocarcinoma of the lungspecialtyoncology