drofenine drofenine drofenine is an antimuscarinic antispasmodic drug used for relaxing smooth muscle, thereby treating conditions, such as: dysmenorrhea, and pain in the gastrointestinal tract, biliary passages, and urogenital tract. drofenine is assumed to work by increasing the levels of the protein trpv3. drofenineidentifiers iupac name 2-(diethylamino)ethyl 2-cyclohexyl-2-phenylacetate cas number1679-76-1pubchem cid3166chemspider3054unii4qwv355536chebichebi:93825chemblchembl442444comptox dashboard (epa)dtxsid0048472 echa infocard100.114.553 chemical and physical dataformulac20h25no3molar mass327.424 g·mol−13d model (jsmol)interactive image smiles ccn(cc)ccoc(=o)c(c1ccccc1)c2=cc=cc=c2 inchi inchi=1s/c20h31no2/c1-3-21(4-2)15-16-23-20(22)19(17-11-7-5-8-12-17)18-13-9-6-10-14-18/h5,7-8,11-12,18-19h,3-4,6,9-10,13-16h2,1-2h3key:agjblwclqckrjp-uhfffaoysa-n