zomebazam zomebazam zomebazam produced by hoechst is a pyrazolodiazepinone derivative drug with anxiolytic properties. it is structurally related to razobazam and zometapine. zomebazamidentifiers iupac name 1,3,8-trimethyl-4-phenylpyrazolodiazepine-5,7-dione cas number78466-70-3 ypubchem cid132677chemspider117132 nuniig563y6g60kchemical and physical dataformulac15h16n4o2molar mass284.319 g·mol−13d model (jsmol)interactive image smiles o=c1n(c2c(n(c(=o)c1)c)n(nc2c)c)c3ccccc3 inchi inchi=1s/c15h16n4o2/c1-10-14-15(18(3)16-10)17(2)12(20)9-13(21)19(14)11-7-5-4-6-8-11/h4-8h,9h2,1-3h3 nkey:bfwacmhtivuwjs-uhfffaoysa-n n ny (what is this?) (verify) synthesis synthesis: patent: the catalytic hydrogenation of n,2,5-trimethyl-4-phenyldiazenylpyrazol-3-amine cid:136203602 (1) over raney nickel gives 4-amino-1,3-dimethyl-5-methylaminopyrazole, cid:10219477 (2). treatment with methyl malonyl chloride (3) gives 4-a-ethoxycarbonylacetylamino-1,3-dimethyl-5-methylaminopyrazole, cid:20561101 (4). base catalyzed lactamization gives (5). the goldberg reaction completes the synthesis zomebazam (6).