paraneoplastic acrokeratosis paraneoplastic acrokeratosis paraneoplastic acrokeratosis, or bazex syndrome is a cutaneous condition characterized by psoriasiform changes of hands, feet, ears, and nose, with involvement of the nails and periungual tissues being characteristic and indistinguishable from psoriatic nails. the condition is associated with carcinomas of the upper aerodigestive tract.: 665 this article is about the cutaneous condition bazex syndrome. for the inherited condition bazex syndrome, see bazex–dupré–christol syndrome. paraneoplastic acrokeratosisother namesacrokeratosis paraneoplastica of bazex and acrokeratosis neoplastica)specialtydermatology history this was first reported by the french dermatologist, andre bazex (1911–1988), in 1945. contrary to some publications, he did not die in 1944, as a victim of the battle for france, but instead, was alive and well and continued his research on skin diseases up until his retirement in 1980.