cyclopentamine cyclopentamine cyclopentamine (trade names clopane, cyclonarol, cyclosal, cyklosan, nazett, sinos, among others) is a sympathomimetic alkylamine, classified as a vasoconstrictor. cyclopentamine was indicated in the past as an over-the-counter (otc) medication for use as a nasal decongestant, notably in europe and australia, but has now been largely discontinued. cyclopentamineclinical dataother namesn,α-dimethyl-cyclopenaneethylamineroutes ofadministrationtopical (nasal spray)atc coder01aa02 (who) legal statuslegal status in general: uncontrolled identifiers iupac name (rs)-1-cyclopentyl-n-methylpropan-2-amine cas number102-45-4 ypubchem cid7608drugbankdb08999 nchemspider7326 yuniiwb9q6m8o60keggd07370 ychemblchembl329203 ychemical and physical dataformulac9h19nmolar mass141.258 g·mol−13d model (jsmol)interactive imagechiralityracemic mixtureboiling point171 °c (340 °f) smiles n(c)c(cc1cccc1)c inchi inchi=1s/c9h19n/c1-8(10-2)7-9-5-3-4-6-9/h8-10h,3-7h2,1-2h3 ykey:hfxkqszzzpglkq-uhfffaoysa-n y ny (what is this?) (verify) pharmacology cyclopentamine acts as a releasing agent of the catecholamine neurotransmitters norepinephrine (noradrenaline), epinephrine (adrenaline), and dopamine. its effects on norepinephrine and epinephrine mediate its decongestant effects, while its effects on all three neurotransmitters are responsible for its stimulant properties. when ingested orally in sufficient quantities, cyclopentamine produces similar effects to amphetamine, methamphetamine, and propylhexedrine. chemistry cyclopentamine is the cyclopentane homolog of propylhexedrine, differing only in terms of the contracted ring size of a cyclopentane, containing one —ch2— unit less than the cyclohexyl group. in terms of the acyclic part of the molecule, both cyclopentamine and propylhexedrine are the same as methamphetamine, all three molecules containing the 2-methylaminopropyl side-chain. the difference between them is that whereas methamphetamine is an aromatic molecule containing a phenyl group, cyclopentamine and propylhexedrine are entirely aliphatic and contain no delocalized electrons at all. the effect that this has on potency is that the reduced alicyclic-alkylamines are weaker than unsaturated (meth)amphetamine.