chromosome 10 chromosome 10 chromosome 10 is one of the 23 pairs of chromosomes in humans. people normally have two copies of this chromosome. chromosome 10 spans about 134 million base pairs (the building material of dna) and represents between 4 and 4.5 percent of the total dna in cells. chromosome 10human chromosome 10 pair after g-banding.one is from mother, one is from father.chromosome 10 pair in human male karyogram.featureslength (bp)134,758,134 bp(chm13)no. of genes706 (ccds)typeautosomecentromere positionsubmetacentric(39.8 mbp)complete gene listsccdsgene listhgncgene listuniprotgene listncbigene listexternal map viewersensemblchromosome 10entrezchromosome 10ncbichromosome 10ucscchromosome 10full dna sequencesrefseqnc_000010 (fasta) genbankcm000672 (fasta) genes number of genes the following are some of the gene count estimates of human chromosome 10. because researchers use different approaches to genome annotation their predictions of the number of genes on each chromosome varies (for technical details, see gene prediction). among various projects, the collaborative consensus coding sequence project (ccds) takes an extremely conservative strategy. so ccds's gene number prediction represents a lower bound on the total number of human protein-coding genes. estimated by protein-coding genes non-coding rna genes pseudogenes source release date ccds706—— 2016-09-08 hgnc708244614 2017-05-12 ensembl728881568 2017-03-29 uniprot750—— 2018-02-28 ncbi754842654 2017-05-19 gene list the following is a partial list of genes on human chromosome 10. for complete list, see the link in the infobox on the right. afap1l2: actin filament associated protein 1 like 2 all1 encoding protein leukemia, acute lymphocytic, susceptibility to, 1 alox5: arachidonate 5-lipoxygenase (processes essential fatty acids to leukotrienes, which are important agents in the inflammatory response; also facilitates development and maintenance of cancer stem cells, slow-dividing cells thought to give rise to a variety of cancers, including leukemia) ankrd22: encoding protein ankyrin repeat domain 22 arhgap21: rho gtpase activating protein 21 arid5b: encoding protein at-rich interactive domain-containing protein 5b armh3: armadillo like helical domain containing 3 as3mt: encoding enzyme arsenite methyltransferase avpi1: encoding protein arginine vasopressin-induced protein 1 c10orf67: chromosome 10 open reading frame 67 c10orf99: encoding protein chromosome 10 open reading frame 99 camk1d: calcium/calmodulin-dependent protein kinase id ccar1: cell division cycle and apoptosis regulator 1 ccdc3: coiled-coil domain-containing protein 3 ccdc186: encoding protein ccdc186 ccny: cyclin-y cdc123: cell division cycle protein 123 homolog cdh23: cadherin-like 23 cdnf: cerebral dopamine neurotrophic factor cefip: encoding protein cardiac-enriched fhl2-interacting protein commd3-bmi1: commd3-bmi1 readthrough cpxm2: encoding protein carboxypeptidase x, m14 family member 2 cutc: copper homeostasis protein cutc homolog cxcl12: chemokine (c-x-c motif) ligand 12, sdf-1, scyb12 ddx50: dexd-box helicase 50 depp: decidual protein induced by progesterone dhx32: deah-box helicase 32 dip2c: encoding protein disco interacting protein 2 homolog c dkk1: dickkopf-related protein 1 dnajc12: dnaj (hsp40) homolog, subfamily c, member 12 dnajc9: dnaj (hsp40) homolog, subfamily c, member 9 dpysl4: dihydropyrimidinase-related protein 4 ebln1: encoding protein endogenous bornavirus-like nucleoprotein 1 ecd: ecdysoneless cell cycle regulator egr2: early growth response 2 (krox-20 homolog, drosophila) eif5ap1: eukaryotic translation initiation factor 5a-like 1 epc1: enhancer of polycomb homolog 1 ercc6: excision repair cross-complementing rodent repair deficiency, complementation group 6 fam107b: family with sequence similarity 107, member b fam13c: family with sequence similarity 13, member c fam170b: encoding protein family with sequence similarity 170 member b fam188a: family with sequence similarity 188, member a fam208b: encoding protein fam208b fam213a: family with sequence similarity 213, member a fam25bp encoding protein protein fam25 fas-as1, long non-coding rna fbxl15: encoding protein f-box and leucine rich repeat protein 15 fgfr2: fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, crouzon syndrome, pfeiffer syndrome, jackson–weiss syndrome) fra10ac1: fragile site, folic acid type frat1: wnt signaling pathway regulator frat2: wnt signaling pathway regulator frmpd2 encoding protein ferm and pdz domain containing 2 gata3: encoding the gata3 transcription factor. gata3 is critical for the embryonic development of the parathyroid gland, neural component of hearing, and kidney. haploinsufficiency of the gene underlies a rare disorder, the hypoparathyrodism, deafness, and renal dysplasia syndrome ghitm: growth hormone-inducible transmembrane protein gprin2: g protein-regulated inducer of neurite outgrowth 2 gtpbp4: nucleolar gtp-binding protein 4 hells: lymphoid-specific helicase hkdc1: hexokinase domain containing 1 kin: dna/rna-binding protein kin17 lhpp: encoding protein phospholysine phosphohistidine inorganic pyrophosphate phosphatase mtg1: mitochondrial gtpase 1 npm3: nucleoplasmin-3 nrbf2: nuclear receptor-binding factor 2 nsmce4a: non-smc element 4 homolog a otud1: encoding protein otu deubiquitinase 1 papss2: encoding enzyme bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 pcbd1: 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (tcf1) pcdh15: protocadherin 15 pi4k2a: phosphatidylinositol 4-kinase 2-alpha pip4k2a: phosphatidylinositol 5 phosphate 4-kinase type-2 alpha pitrm1: pitrilysin metallopeptidase 1 plekhs1 encoding protein pleckstrin homology domain containing s1 plxdc2: plexin domain-containing protein 2 prap1: encoding protein proline rich acidic protein 1 proser2: proline and serine rich 2 or c10orf47 pten gene: phosphatase and tensin homolog (mutated in multiple advanced cancers 1) ret: ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, hirschsprung disease) rpp30: ribonuclease p protein subunit p30 rrp12: ribosomal rna processing 12 homolog rsu1: ras suppressor protein 1 rtkn2: encoding protein rhotekin 2 sczd11: encoding protein schizophrenia susceptibility locus, chromosome 10q-related sgpl1: sphingosine-1-phosphate lyase 1 shtn1: encoding protein shootin 1 slc16a12: encoding protein solute carrier family 16 member 12 smndc1: survival motor neuron domain containing 1 spg9 encoding protein spastic paraplegia 9 (autosomal dominant) srgn: serglycin stambpl1: stam binding protein like 1 stox1: encoding protein storkhead box 1 supv3l1: suv3 like rna helicase syce1: encoding protein synaptonemal complex central element protein 1 tacc2 encoding protein transforming acidic coiled-coil-containing protein 2 tbc1d12: tbc1 domain family, member 12 tctn3: tectonic family member 3 tmem10: opalin tmem254: encoding protein transmembrane protein 254 tmem26: encoding protein transmembrane protein 26 tmem72: encoding protein transmembrane protein 72 tysnd1: encoding protein trypsin domain containing 1 ucn3: urocortin-3 uros: uroporphyrinogen iii synthase (congenital erythropoietic porphyria) usmg5: up-regulated during skeletal muscle growth protein 5 usp54: encoding protein ubiquitin specific peptidase 54 usp6nl: usp6 n-terminal like protein utf1: undifferentiated embryonic cell transcription factor 1 vim-as1: vim antisense rna 1 washc2c: wash complex subunit 2c wbp1l: ww domain binding protein 1-like znf37a: zinc finger protein 37a znf438: zinc finger protein 438 zranb1: zinc finger ranbp2-type containing 1 diseases and disorders the following diseases are related to genes on chromosome 10: apert syndrome barakat syndrome beare–stevenson cutis gyrata syndrome charcot–marie–tooth disease cockayne syndrome congenital erythropoietic porphyria cowden syndrome crouzon syndrome genitopatellar syndrome glioblastoma multiforme hadds syndrome hermansky–pudlak syndrome hirschprung disease jackson–weiss syndrome multiple endocrine neoplasia type 2 nonsyndromic deafness pfeiffer syndrome porphyria spondyloepimetaphyseal dysplasia, pakistani type tetrahydrobiopterin deficiency thiel–behnke corneal dystrophy usher syndrome wolman syndrome young-simpson syndrome cytogenetic band g-banding ideograms of human chromosome 10g-banding ideogram of human chromosome 10 in resolution 850 bphs. band length in this diagram is proportional to base-pair length. this type of ideogram is generally used in genome browsers (e.g. ensembl, ucsc genome browser).g-banding patterns of human chromosome 10 in three different resolutions (400, 550 and 850). band length in this diagram is based on the ideograms from iscn (2013). this type of ideogram represents actual relative band length observed under a microscope at the different moments during the mitotic process. g-bands of human chromosome 10 in resolution 850 bphs chr. arm band iscnstart iscnstop basepairstart basepairstop stain density 10p 15.3022913,000,000 gneg 10p 15.22293293,000,0013,800,000 gpos25 10p 15.13296303,800,0016,600,000 gneg 10p 146309176,600,00112,200,000 gpos75 10p 13917117512,200,00117,300,000 gneg 10p 12.331175136117,300,00118,300,000 gpos75 10p 12.321361143218,300,00118,400,000 gneg 10p 12.311432160418,400,00122,300,000 gpos75 10p 12.21604166222,300,00124,300,000 gneg 10p 12.11662189124,300,00129,300,000 gpos50 10p 11.231891206329,300,00131,100,000 gneg 10p 11.222063223531,100,00134,200,000 gpos25 10p 11.212235240634,200,00138,000,000 gneg 10p 11.12406262138,000,00139,800,000 acen 10q 11.12621285039,800,00141,600,000 acen 10q 11.212850305141,600,00145,500,000 gneg 10q 11.223051325245,500,00148,600,000 gpos25 10q 11.233252340948,600,00151,100,000 gneg 10q 21.13409375351,100,00159,400,000 gpos100 10q 21.23753383959,400,00162,800,000 gneg 10q 21.33839409762,800,00168,800,000 gpos100 10q 22.14097446968,800,00173,100,000 gneg 10q 22.24469465573,100,00175,900,000 gpos50 10q 22.34655497075,900,00180,300,000 gneg 10q 23.14970520080,300,00186,100,000 gpos100 10q 23.25200533186,100,00187,700,000 gneg 10q 23.315331555887,700,00191,100,000 gpos75 10q 23.325558567291,100,00192,300,000 gneg 10q 23.335672588792,300,00195,300,000 gpos50 10q 24.15887597395,300,00197,500,000 gneg 10q 24.25973613197,500,001100,100,000 gpos50 10q 24.3161316202100,100,001101,200,000 gneg 10q 24.3262026317101,200,001103,100,000 gpos25 10q 24.3363176374103,100,001104,000,000 gneg 10q 25.163746646104,000,001110,100,000 gpos100 10q 25.266466761110,100,001113,100,000 gneg 10q 25.367616890113,100,001117,300,000 gpos75 10q 26.1168907090117,300,001119,900,000 gneg 10q 26.1270907219119,900,001121,400,000 gpos50 10q 26.1372197506121,400,001125,700,000 gneg 10q 26.275067721125,700,001128,800,000 gpos50 10q 26.377218050128,800,001133,797,422 gneg