gadobenic acid gadobenic acid gadobenic acid (inn, brand name multihance) is a complex of gadolinium with the ligand bopta. in the form of the methylglucamine salt meglumine gadobenate (innm) or gadobenate dimeglumine (usan), it is used as a gadolinium-based mri contrast medium. gadobenic acidclinical datatrade namesmultihanceother namesgadobenate dimeglumine (usan us)ahfs/drugs.comprofessional drug factsatc codev08ca08 (who) legal statuslegal status uk: pom (prescription only) us: ℞-only identifiers iupac name dihydrogen gadolinate(2−). cas number113662-23-0 npubchem cid105124drugbankdb00743 nchemspider94843 nunii15g12l5x8kkeggd08018 ychemblchembl1200571 ncomptox dashboard (epa)dtxsid00921145 chemical and physical dataformulac22h28gdn3o11molar mass667.73 g·mol−13d model (jsmol)interactive image smiles ...c(=o)cn(cc()=o)ccn(cc()=o)ccn(cc()=o)c(c()=o)cocc1ccccc1 inchi inchi=1s/c22h31n3o11.gd/c26-18(27)10-23(6-7-24(11-19(28)29)12-20(30)31)8-9-25(13-21(32)33)17(22(34)35)15-36-14-16-4-2-1-3-5-16;/h1-5,17h,6-15h2,(h,26,27)(h,28,29)(h,30,31)(h,32,33)(h,34,35);/q;+3/p-3 nkey:mxzrotbgjuuxid-uhfffaoysa-k n ny (what is this?) (verify) bopta is a derivative of dtpa in which one terminal carboxyl group, –c(o)oh is replaced by -c–o–ch2c6h5. thus gadobenic acid is closely related to gadopentetic acid. bopta itself was first synthesized in 1995. in the "gadobenate" ion gadolinium ion is 9-coordinate with bopta acting as an 8-coordinating ligand. the ninth position is occupied by a water molecule, which exchanges rapidly with water molecules in the immediate vicinity of the strongly paramagnetic complex, providing a mechanism for mri contrast enhancement. 139la nmr studies on the diamagnetic la-bopta2− complex suggest that the gd complex maintains in solution the same kind of coordination as found, by x-ray crystallography, in the solid state for gd-bopta disodium salt.