tolvaptan phosphate tolvaptan phosphate tolvaptan phosphate is a drug used for the treatment of cardiac edema. it is a prodrug of tolvaptan, formulated as the salt tolvaptan sodium phosphate, for intravenous administration. tolvaptan phosphate is converted into the active drug tolvaptan in the human body following administration. tolvaptan phosphateclinical datatrade namessamtasuother namestolvaptan sodium phosphate; opc-61815identifiers iupac name benzoyl]-2,3,4,5-tetrahydro-1-benzazepin-5-yl] dihydrogen phosphate cas number942619-74-1pubchem cid146035877chemspider17342600uniiy4p6ws9qvfkeggd11659chemical and physical dataformulac26h26cln2o6pmolar mass528.93 g·mol−13d model (jsmol)interactive image smiles cc1=cc=cc=c1c(=o)nc2=cc(=c(c=c2)c(=o)n3cccc(c4=c3c=cc(=c4)cl)op(=o)(o)o)c inchi inchi=inchi=1s/c26h26cln2o6p/c1-16-6-3-4-7-20(16)25(30)28-19-10-11-21(17(2)14-19)26(31)29-13-5-8-24(35-36(32,33)34)22-15-18(27)9-12-23(22)29/h3-4,6-7,9-12,14-15,24h,5,8,13h2,1-2h3,(h,28,30)(h2,32,33,34)/t24-/m1/s1key:xtcfgvrvasprtk-xmmpixpasa-n it was developed by otsuka pharmaceutical co. and was approved for use in japan in 2022.