madam-6 madam-6 madam-6, or 2,n-dimethyl-4,5-methylenedioxyamphetamine, is a lesser-known recreational drug of the methamphetamine class, similar in structure to mdma (ecstasy). madam-6 was first synthesized by alexander shulgin. in shulgin's book pihkal, the minimum dosage is listed as greater than 280 mg, and the duration is unknown. madam-6 produces few to no effects and shulgin describes it as "not active". very little data exists about the pharmacological properties, metabolism, and toxicity of madam-6. madam-6 names preferred iupac name n-methyl-1-(6-methyl-2h-1,3-benzodioxol-5-yl)propan-2-amine other names 6-methyl-mdma identifiers cas number 207740-46-3 3d model (jsmol) interactive image chemspider 21106340 pubchem cid 44719578 unii w3h6ghj73c comptox dashboard (epa) dtxsid80660368 inchi inchi=1s/c12h17no2/c1-8-4-11-12(15-7-14-11)6-10(8)5-9(2)13-3/h4,6,9,13h,5,7h2,1-3h3key: crqpdniupwxpnk-uhfffaoysa-n smiles c1(=cc2=c(c=c1cc(c)nc)oco2)c properties chemical formula c12h17no2 molar mass 207.273 g·mol−1 except where otherwise noted, data are given for materials in their standard state (at 25 °c , 100 kpa). infobox references madam-6 has been studied for its potential antiparkinsonian effects. however, there are no clinical trials suggesting the drug is effective against parkinson's disease.