fibrate fibrate in pharmacology, the fibrates are a class of amphipathic carboxylic acids and esters. they are derivatives of fibric acid (phenoxyisobutyric acid). they are used for a range of metabolic disorders, mainly hypercholesterolemia (high cholesterol), and are therefore hypolipidemic agents. fibratesdrug classfenofibrate, one of the most popular fibratesclass identifiersusehypertriglyceridemia and hypercholesterolaemiaatc codec10abbiological targetpparclinical datawebmdmedicinenet