edoxudine edoxudine edoxudine (or edoxudin) is an antiviral drug. it is an analog of thymidine, a nucleoside. edoxudineclinical dataatc coded06bb09 (who) legal statuslegal status in general: ℞ (prescription only) identifiers iupac name 5-ethyl-1-pyrimidine-2,4-dione cas number15176-29-1 ypubchem cid66377chemspider59752 nunii15zqm81y3rchemblchembl318153 ncomptox dashboard (epa)dtxsid4045890 echa infocard100.035.645 chemical and physical dataformulac11h16n2o5molar mass256.25514 g·mol−13d model (jsmol)interactive image smiles o=c/1nc(=o)n(\c=c\1cc)2o((o)c2)co inchi inchi=1s/c11h16n2o5/c1-2-6-4-13(11(17)12-10(6)16)9-3-7(15)8(5-14)18-9/h4,7-9,14-15h,2-3,5h2,1h3,(h,12,16,17)/t7-,8+,9+/m0/s1 nkey:xacknlszyyiaco-djldldebsa-n n ny (what is this?) (verify) it has shown effectiveness against herpes simplex virus. synthesis edoxudine synthesis: synthesis via organopalladium intermediates: mercuration of the 2'-deoxyuridine 1 leads to the organometallic derivative 2; reaction of that with ethylene in the presence dilithiopalladium tetrachloride gives the alkylation product 3; this is reduced catalytically in situ. there is thus obtained the antiviral agent edoxudine 4.