bisulepin bisulepin bisulepin is strong and relatively selective antihistamine (h1 antagonist) with hypnotic, antiadrenergic and very weak anticholinergic and antiserotonergic effects. bisulepin is marketed in the czech republic and slovakia under the trademark dithiaden as tablets and injections. bisulepinclinical dataatc coder06ax (who) identifiers iupac name (3e)-n,n-dimethyl-3-(thienobenzothiepin-4(9h)-ylidene)propan-1-amine cas number42504-83-6pubchem cid6537425chemspider5020597unii595726r32uchebichebi:135277comptox dashboard (epa)dtxsid40973608 echa infocard100.024.867 chemical and physical dataformulac17h19ns2molar mass301.47 g·mol−13d model (jsmol)interactive image smiles cn(c)cc\c=c1\c2ccsc2scc2ccccc12 the registered active form is the trans- (i.e. e-) isomer.