indantadol indantadol indantadol (chf-3381, v-3381) is a drug which was formerly being investigated as an anticonvulsant and neuroprotective and is now under development for the treatment of neuropathic pain and chronic cough in europe by vernalis and chiesi. it acts as a competitive, reversible, and non-selective monoamine oxidase inhibitor, and as a low affinity, non-competitive nmda receptor antagonist. a pilot study of indantadol for chronic cough was initiated in october 2009 and in april 2010 it failed to achieve significant efficacy in neuropathic pain in phase iib clinical trials. indantadolclinical dataroutes ofadministrationoralatc codenonelegal statuslegal status in general: uncontrolled identifiers iupac name n-(2,3-dihydro-1h-inden-2-yl)glycinamide cas number202844-10-8chemspider16017060uniiz3867b9sqpcomptox dashboard (epa)dtxsid00942416 chemical and physical dataformulac11h14n2omolar mass190.246 g·mol−13d model (jsmol)interactive image smiles ncc(=o)nc1cc2ccccc2c1