arylalkylamine arylalkylamine substituted arylalkylamines are a group of chemical compounds. two major classes of arylalkylamines include indolylalkylamines (e.g., tryptamines ) and phenylalkylamines (e.g., phenethylamines and amphetamines ), which consist of the monoamine neurotransmitters as well as clinically-used and recreationally-abused monoaminergic drugs, including psychostimulants, anorectics, wakefulness-promoting agents, bronchodilators, decongestants, antidepressants, entactogens, and psychedelics, among others.