desmoplastic trichoepithelioma desmoplastic trichoepithelioma a desmoplastic trichoepithelioma is a cutaneous condition characterized by a solitary, firm skin lesion on the face.: 672 desmoplastic trichoepitheliomadesmoplastic trichoepithelioma or sclerosing epithelial hamartoma treatment desmoplastic trichoepithelioma is a benign tumour and can be managed safely with surgical removal, electrodesiccation and curettage.