prion (disambiguation) prion (disambiguation) prion is a misfolded proteins which characterize several fatal neurodegenerative diseases in humans and many other animals. it may also refer to: names eran prion (born 1974), israeli musician and music producer based in tel aviv places prion island, located at 2.4 km (1.5 mi) north-northeast of luck point, lying in the bay of isles, south georgia science fungal prion, prion that infects fungal hosts prion protein, human gene encoding for the major prion protein prp (for prion protein) prion diseases, group of progressive and invariably fatal symptoms affecting the brain (encephalopathies) and nervous system of many animals prion pruritus, intense itching during the prodromal period of the creutzfeldt–jakob disease prion pseudoknot, predicted rna pseudoknot structure found in prion protein mrna other uses prion humour classics, series of small-format hardback novels published by prion books in the uk national prion clinic (uk), a british specialist prion disease clinic