jzl184 jzl184 jzl184 is an irreversible inhibitor for monoacylglycerol lipase (magl), the primary enzyme responsible for degrading the endocannabinoid 2-arachidonoylglycerol (2-ag). it displays high selectivity for magl over other brain serine hydrolases, including the anandamide-degrading enzyme fatty acid amide hydrolase (faah), thereby making it a useful tool for studying the effects of endogenous 2-ag signaling, in vivo. administration of jzl184 to mice was reported to cause dramatic elevation of brain 2-ag leading to several cannabinoid-related behavioral effects. jzl184 names preferred iupac name 4-nitrophenyl 4-piperidine-1-carboxylate identifiers cas number 1101854-58-3 y 3d model (jsmol) interactive image chebi chebi:95015 n chembl chembl576786 n chemspider 21467840 n pubchem cid 25021165 unii 7mz1i2j68a inchi inchi=1s/c27h24n2o9/c30-26(38-21-5-3-20(4-6-21)29(32)33)28-11-9-17(10-12-28)27(31,18-1-7-22-24(13-18)36-15-34-22)19-2-8-23-25(14-19)37-16-35-23/h1-8,13-14,17,31h,9-12,15-16h2 nkey: segyokhggfkmcx-uhfffaoysa-n n smiles c1cc(ccc1(=o))oc(=o)n2ccc(cc2)c(c3ccc4c(c3)oco4)(c5ccc6c(c5)oco6)o properties chemical formula c27h24n2o9 molar mass 520.15 g/mol appearance pale yellow solid except where otherwise noted, data are given for materials in their standard state (at 25 °c , 100 kpa). n verify (what is yn ?) infobox references