aa560 aa560 aa560 is an orally active nonsteroidal antiandrogen (nsaa) that was developed in japan and was first described in the literature in 1977 but was never marketed. it is an anilide derivative and analogue of the nsaa flutamide, and shows greater in vivo antiandrogenic potency than does flutamide. similarly to flutamide, aa560 is a selective antagonist of the androgen receptor (ar) and consequently shows progonadotropic effects by increasing levels of gonadotropins and testosterone via disinhibition of the hypothalamic-pituitary-gonadal axis. aa560clinical dataother namesaa-560; n-(2-chloromethyl-2-hydroxypropionyl)-3,4,5-trichloroanilineroutes ofadministrationby mouthdrug classnonsteroidal antiandrogenidentifiers iupac name 2-hydroxy-2-methyl-n-(3,4,5-trichlorophenyl)propanamide cas number65372-80-7 ypubchem cid125204chemspider111441unii3hs29b4w75comptox dashboard (epa)dtxsid80983988 chemical and physical dataformulac10h10cl3no2molar mass282.55 g·mol−13d model (jsmol)interactive image smiles cc(c)(c(=o)nc1=cc(=c(c(=c1)cl)cl)cl)o inchi inchi=1s/c10h10cl3no2/c1-10(2,16)9(15)14-5-3-6(11)8(13)7(12)4-5/h3-4,16h,1-2h3,(h,14,15)key:fvepmrzjquylra-uhfffaoysa-n