methylatropine methylatropine methylatropine (trade name eumydrin) is a belladonna derivative. methylatropineclinical dataatc codea03bb02 (who) identifiers iupac name (1r,5r)-3--8,8-dimethyl-8-azoniabicyclooctane cas number31610-87-4pubchem cid1550101drugbankdb13833chemspider5652unii80719i460hchemblchembl1179176chemical and physical dataformulac18h26no3molar mass304.410 g·mol−13d model (jsmol)interactive image smiles c1(c2ccc1cc(c2)oc(=o)c(co)c3=cc=cc=c3)c inchi inchi=1s/c18h26no3/c1-19(2)14-8-9-15(19)11-16(10-14)22-18(21)17(12-20)13-6-4-3-5-7-13/h3-7,14-17,20h,8-12h2,1-2h3/q+1/t14-,15+,16?,17-/m0/s1key:pipajlpnwzmyqa-wfvvyapdsa-n ny (what is this?) (verify) in 1902, the bayer company introduced methylatropine, a quaternary ammonium salt of atropine, as a mydriatic for dilation of the pupil during ophthalmic examination under the brand name of eumydrin. because of its highly polar nature it penetrated less readily into the central nervous system than did atropine; hence it was introduced for relieving pyloric spasm in infants. the blocking potency of methylatropine is approximately 10-20 times higher than that of atropine at neuromuscular and ganglionic synapses.