was responsible for some of the paranoia, mostly that one is being watched or followed. however, the disease was still mostly psychological. holovirus red dwarf: quarantine discovered, contracted and possibly created by viral researcher hildeguard lanstrom, this nasty condition can only be passed between holograms. it can be transmitted across radio-waves and drains the victim's life-force while endowing them with powers such as telepathy, telekinesis and hex-vision. the affected tends to go insane long before their demise. suggested treatment: a remote link to the hologram disk projection system, a detachable power transfer adapter capable of holding spikes of up to five million volts, and a b47/7rf resistor. plus confiscation of equally deranged penguin glove-puppet hopper virus doctor who: orphan 55 a macroscopic virus able to be transmitted both biologically and through computers. in humans, symptoms include wiggling of the fingers, temporary paralysis of the lower half and hallucinations of bats. in computers, the virus wrecks the hard- and soft-ware. it can be cured in humans by pinching the ear of the infected, causing them to sneeze the virus out, and in computers using a debug script. hopping cough the smurfs a plague created by the smurfs' enemy gargamel to use as a biological weapon against them; a victim of this contagious disease coughs violently and leaps very high into the air with each cough. irumodic syndrome star trek the next generation a neurological disease caused by a defect in the brain's parietal lobe. it can take years for the illness to actually develop. in one potential alternate reality, jean-luc picard had this defect and developed the syndrome over a 25-year period. imminent death syndrome mr. show a terminal disease in which the affected individual may experience death at any given time, usually within 80–100 years. jelly measles jelly jamm (musical aurora) a jammbonian illness. symptoms include a pitched-up voice, itchy spots, increased body weight (?), and a fever so high it causes one to walk on the walls. the only cure is a spoonful of terrible-tasting medicine. johnny-itis the johnny test episode of the same name a condition caused by drinking an unnamed fictional substance only described as "an unstable isotope." symptoms may include red spots on the skin and a purple tongue, followed by violent bloating and then an explosion. joy virus the amazing world of gumball (the joy) a virus that is caused by a "wonder hug". its early to later symptoms include heavily dilated pupils, the victim hallucinating the world around them as happy and cute, a huge open-mouthed smile, and vibrant rainbow-colored drool, and its final stage causes the victim to die of happiness and be reanimated as a happy zombie-like creature. the virus spread throughout the school via hugging or by touching . those infected were dubbed "huggers" by the character miss simian. the cure was hearing anything depressing like the song "moonlight sonata". jungle worms icarly a disease that causes fever, sweating, and vomiting. the disease itself only appears a few times in the show. carly contracts the disease several times in her life, however, she is declared a healthy carrier, causing a doctor to advise her to avoid contact with other infected persons and cute boys. she later inadvertently infects someone via an infected glass of water. kalavirus 12 monkeys kalavirus, also referred to as m5-10, is a plague that kills ninety-eight percent of the world population. although not released directly by the army of the 12 monkeys, their guiding hand and influence in its creation and release is undeniable. krabby patty withdrawal spongebob squarepants (pat no pay) a simple hunger-related disorder characterised by someone's stomach shrinking, then going flabby. patrick was suffering from this, and therefore required eating several krabby patties to cure him of this. lackadaisy-cathro disease ed, edd n eddy (a case of ed) main symptoms include "rationalising of mundane circumstances, habitual cleanliness and an abnormal fixation to head-wear. other symptoms include mumbled words and "weakness in the lower extremities". the character edd was falsely diagnosed with it by his friends as part of a prank. lazar's disease doctor who: terminus a leprosy-like disease, the only cure is a dose of radiation. luck virus red dwarf a positive viral strain that makes the infected person lucky for a temporary time. lurgy (the dreaded lurgi) goon showthe goon show a disease that causes anyone who catches it to say nothing but 'eeee-yakkaboo!'. "lurgy" has become a british slang for "fictional disease du jour." macrovirus star trek: voyager an airborne pathogen-by-proxy that infects endothermic humanoids with a virus, causing the host to become lethargic and produce more macroviruses until the host wastes away and dies. when some of the bugs invaded voyager, the emh was able to synthesize a cure. mad snail disease spongebob squarepants (once bitten) a psychosomatic disease that is supposedly spread by an infected snail's bite. the imagined symptoms are as follows. in the first stage of the disease, toxins enter the body through the bloodstream, moving through the host until the host's body is taken over. symptoms include: bloodshot eyes, messy pants, untrimmed toenails, ticklish ribcage, and loss of balance. after final stage, the host becomes a "zombie". in the episode "once bitten", gary bites squidward and most of the citizens of bikini bottom. due to misinformation over the disease, they believe they are zombies and chase spongebob until dr. gil gilliams, sde, se (snail disease expert and snail expert) informs them that "mad snail disease" is nothing more than an urban legend. its name is a reference to prion diseases like bovine spongiform encephalopathy and creutzfeldt–jakob disease. infected snails show rabies like symptoms, including irritability, foaming at the mouth and aggression, which in reality was caused by a splinter gary had after squidward tried to make the area around his house snail-proof. mad cow disease/mad zombie disease the simpsons boston legal similar to the virus shown on zombieland this plague is non-canonical in the simpsons universe but nonetheless appears in treehouse of horror xx. similar to zombieland, it is transmitted through cows. in this segment, krusty develops a new burger from cannibalistic cows and the effects of this mutate into a virus which turns the victim into a zombie in a matter of seconds. symptoms include drooling saliva at the mouth, blackened bags under the eyes, pale skin, and psychotic behavior like paranoia. the virus can be transmitted through biting. the only known cure is bart simpson, as he ate one of the infected burgers but was immune. on the david e. kelley series boston legal, william shatner as denny crane blames his outré behavior on mad cow disease. magnus oblivio falicitus upright citizens brigade also known as "little donny disease". eponymously named for the character donny, from the sketch comedy tv series upright citizens brigade. donny was oblivious to the fact that he had an "enormous penis". monkeynucleosis hey arnold! a disease that is caused if a person is touched by a monkey. helga thinks she had this disease when a monkey trainer's monkey kissed her on the arm. it seems that the disease leads to death (or, as said in the show, "expiration") there are four symptoms: puffy rash where infected, sweaty palms, loss of appetite, and irritability. on the show, monkeynucleosis is said to have been long debunked by modern science. mono orangosis wizards of waverly place a disease max made up to get sympathy from a girl. it makes the infected person unable to hear, see, taste, smell anything orange. motaba the pretender the "a virus among us" episode borrows its center plot disease from the film outbreak. narrow urethra king of the hill a medical condition that prevents a male from having a normal sperm count, due to their urethra being smaller than an ordinary man. it can pass genetically, yet it is known to skip a generation. there are several techniques to assist in temporarily relieving this problem; however, they are not proven to work. narvik helix the illaria corporation were responsible for the development of the narvik virus which came in two forms: narvik-a, a fatal virus with no current cure and narvik-b, turning those infected with the virus into violent, zombie-like vectors who spread the infection to others. narvik-b is treatable to some degree if treated. pararibulitis dirk gently's holistic detective agency (tv series) todd's sister amanda has pararibulitis, a hereditary disease invented for the show that causes her to experience vivid and painful hallucinations pentapox avatar: the last airbender a fictional disease. "symptoms" include purple spots on the skin (actually sucker marks left by a purple pentapus). the inhabitants of omashu pretended to be infected with pentapox to escape the fire nation-occupied city. petrifold regression doctor who: new earth a condition that causes the affected to turn to stone (similar to petrification). unknown origins. phagethe phage star trek: voyager a necrotizing plague that affects members of the vidiian species. organ transplants are required for survival. klingon dna seems to be highly resistant to the phage. it was cured by the think tank. pigeon influenza sløborn this disease causes flu-like symptoms, as well as symptoms of hemorrhagic fever, with its victims hemorrhaging from their eyes, nose, and coughing up blood.it has caused a large-scale epidemic in india and latin america, later also causing a crisis in germany, prompting the country's armed forces to step in. "pinkeye" pinkeye (south park) an infection caused by the accidental combination of embalming chemicals and worcestershire sauce (originally dr. pepper according to trey and matt, the creators from show). it results in a zombie apocalypse within south park. its initial host is kenny. to be cured, the initial host must be killed, in a similar fashion to vampire-based folklore. its symptoms are greenish pale skin, a craving for human flesh, and several other zombie-like behaviors and characteristics. polaris extremis hogans heroes episode: up in klink's room a rare disease found only among eskimoes. symptoms are pains in nerve endings in the ends of the fingers, craving for greens in the diet, and articular motory vascular spasms. hogan faked contracting the disease to gain entry into a nazi hospital operated by doctor ernst klaus, a specialist in eskimo diseases, so that he could obtain information on kriegsmarine battle plans from a deep-cover agent. progressive aging syndrome 2030 ce a widespread disease which limits the human lifespan to thirty years. one character is known to have survived it, albeit in a coma. protomolecule the expanse a highly-infectious extraterrestrial agent created about two billion years ago that infects life forms upon contact and causes unpredictable changes over a period of time. proxyglossariasis duckman a condition which causes someone, while speaking, to occasionally use the next word in the dictionary instead of the one they wanted. appeared in the episode "research and destroy". purity x-files an alien virus that thrived underground on earth, in petroleum deposits. the virus is capable of entering humanoids and assuming control of their bodies. it has sentience and is capable of communicating. it was revealed to be the "life force" of the alien colonists, which they seemingly used to reproduce their kind, as well as infect other alien races in order to conquer the universe. polywater intoxication star trek: "the naked time", star trek: the next generation: "the naked now" a mutated form of water from the planet psi 2000 that spreads by perspiration (or small cuts in the skin) and causes its victims to act in a way similar to intoxication. however, the effects do not wear off and eventually cause victims to make foolish and dangerous decisions. dr. leonard mccoy isolated an antidote, and once it was administered, patients had to be forced to use willpower to combat the symptoms. several decades later, the crew of new enterprise is infected by what seems to be the same disease. in this instance, it is spread by mere touch and is able to infect data, an android. while commander riker learns about the previous incident from the ship's records, mccoy's cure proves ineffective this time, dr. crusher believing it may be mutated. she modifies the old antidote into a new one that cures the affliction and administers it to the crew. random pavarotti disease rex the runt a condition that causes the victim to randomly sing operatic tunes, à la luciano