lymecycline lymecycline lymecycline is a tetracycline broad-spectrum antibiotic. it is approximately 5,000 times more soluble than tetracycline base and is unique amongst tetracyclines in that it is absorbed by an active transport process across the intestinal wall, making use of the same fast and efficient mechanism by which carbohydrates are absorbed. lymecyclineclinical datatrade namestetralysalahfs/drugs.cominternational drug namesroutes ofadministrationby mouthatc codej01aa04 (who) legal statuslegal status au: s4 (prescription only) pharmacokinetic databioavailability100% (oral)elimination half-life10 hoursexcretionkidneyidentifiers iupac name (2s)-6--hydroxymethyl]amino]methylamino]-2-aminohexanoic acid cas number992-21-2 ypubchem cid54707177drugbankdb00256 ychemspider20121315 nunii7d6em3s13pkeggd06884 ycomptox dashboard (epa)dtxsid9045344 echa infocard100.012.357 chemical and physical dataformulac29h38n4o10molar mass602.63 g·mol−13d model (jsmol)interactive image smiles c1(2c3(c(=c(c(=o)3(c(=c2c(=o)c4=c1c=cc=c4o)o)o)c(=o)ncncccc(c(=o)o)n)o)n(c)c)o inchi inchi=1s/c29h38n4o10/c1-28(42)13-7-6-9-17(34)18(13)22(35)19-14(28)11-15-21(33(2)3)23(36)20(25(38)29(15,43)24(19)37)26(39)32-12-31-10-5-4-8-16(30)27(40)41/h6-7,9,14-16,21,31,34,36-37,42-43h,4-5,8,10-12,30h2,1-3h3,(h,32,39)(h,40,41)/t14-,15-,16-,21-,28+,29-/m0/s1 nkey:ahevkyygxvewno-uepzruibsa-n n ny (what is this?) (verify) the greater absorption of lymecycline allows for lower dosages to be used; the standard dose of 408 mg is equivalent to 300 mg tetracycline base and, in its action, to 500 mg tetracycline hydrochloride. lymecycline, unlike tetracycline hydrochloride, is soluble at all physiological ph values. history lymecycline was introduced by farmitalia in 1963. indications lymecycline, like other tetracyclines, is used to treat a range of infections. its better absorption profile makes it preferable to tetracycline for moderately severe acne and typically prescribed for 8 weeks at a time, but alternatives should be sought if no improvement occurs by 3 months. lymecycline capsules side effects lymecycline's side effects can include rash, headache, diarrhoea, nausea, vomiting, dermatitis, inflammation of the liver, hypersensitive reactions, and visual disturbances. when taken for a long period of time, it can cause reflux oesophagitis. recently, the family of tetracycline antibiotics has been associated with thyroid dysfunction in youth.