f-11,461 f-11,461 f-11,461 is a drug that acts as an agonist of the 5-ht1a receptor (ki = 1.36 nm) that has been used as a radioligand in pet studies. it possesses modest affinity for the 5-ht7 (ki = 9.1 nm) and d4 (ki = 8.5 nm) receptors, although the interaction of f-11,461 with these receptors is not detectable with pet due to their relative scarcity in the brain. f-11,461identifiers iupac name 2--1-piperazinyl]butyl]-4-methyl-1,2,4-triazine-3,5(2h,4h)-dione cas number874471-25-7 ypubchem cid10324985chemspider9850903 nuniirkg24j8kjrchemblchembl199824chemical and physical dataformulac23h29n5o3molar mass423.517 g·mol−13d model (jsmol)interactive image smiles o=c1c=nn(c(=o)n1c)ccccn2ccn(c3=cc=cc4=cc=c(o)c=c43)cc2 inchi inchi=inchi=1s/c23h29n5o3/c1-25-22(29)17-24-28(23(25)30)11-4-3-10-26-12-14-27(15-13-26)21-7-5-6-18-8-9-19(31-2)16-20(18)21/h5-9,16-17h,3-4,10-15h2,1-2h3/i2-1key:gktqbpymigxpkg-jvvvgqrlsa-n