hydia hydia hydia is a drug that is used in neuroscience research, which acts as a potent and selective antagonist for the group ii metabotropic glutamate receptors (mglur2/3). it has been useful in the mapping of the group ii mglur receptor proteins and their molecular modeling. hydia is similar in structure to group ii mglur agonists such as eglumetad and pomaglumetad, but the addition of the 3-hydroxy group reverses the activity to a competitive antagonist. other derivatives such as the 3-benzyloxy ether are more potent antagonists than hydia itself. hydiaidentifiers iupac name (1s,2r,3r,5r,6s)-2-amino-3-hydroxybicyclohexane-2,6-dicarboxylic acid pubchem cid9794223chemspider7969990 nchemical and physical dataformulac8h11no5molar mass201.178 g·mol−13d model (jsmol)interactive image smiles c12(2(1o)(c(=o)o)n)c(=o)o inchi inchi=1s/c8h11no5/c9-8(7(13)14)3(10)1-2-4(5(2)8)6(11)12/h2-5,10h,1,9h2,(h,11,12)(h,13,14)/t2-,3+,4-,5-,8-/m0/s1 nkey:ntpxneqcdpwjqa-azdhxylbsa-n n ny (what is this?) (verify)