dixyrazine dixyrazine dixyrazine, also known as dixypazin (oxalate), sold under the brand names ansiolene, esocalm, esucos, metronal, and roscal, is a typical antipsychotic of the phenothiazine group described as a neuroleptic and antihistamine. it was first introduced in germany in 1969. it is used as a neuroleptic, anxiolytic, and antihistamine in doses between 12.5 and 75 mg a day. dixyrazine names iupac name (rs)-2-ethoxy]ethanol other names ucb-3412 identifiers cas number 2470-73-7 y 3d model (jsmol) interactive image chemspider 16265 n echa infocard 100.017.811 ec number 219-591-3 kegg d07865 n pubchem cid 17182 unii 7h368w3ayc y comptox dashboard (epa) dtxsid10947639 inchi inchi=1s/c24h33n3o2s/c1-20(18-26-12-10-25(11-13-26)14-16-29-17-15-28)19-27-21-6-2-4-8-23(21)30-24-9-5-3-7-22(24)27/h2-9,20,28h,10-19h2,1h3 nkey: msyumpgngdntiq-uhfffaoysa-n ninchi=1/c24h33n3o2s/c1-20(18-26-12-10-25(11-13-26)14-16-29-17-15-28)19-27-21-6-2-4-8-23(21)30-24-9-5-3-7-22(24)27/h2-9,20,28h,10-19h2,1h3key: msyumpgngdntiq-uhfffaoyai smiles cc(cn1ccn(cc1)ccocco)cn2c3=cc=cc=c3sc4=cc=cc=c42 properties chemical formula c24h33n3o2s molar mass 427.60272 g/mol pharmacology atc code n05ab01 (who) except where otherwise noted, data are given for materials in their standard state (at 25 °c , 100 kpa). n verify (what is yn ?) infobox references synthesis thieme patent: sodamide alkylation of phenothiazine (1) with 1-bromo-3-chloro-2-methylpropane (2) gives 10-(3-chloro-2-methylpropyl)phenothiazine, cid:12299119 (3). completion of the sidechain by alkylation with 1-piperazine (4) and displacement of the halogen completes the synthesis of dixyrazine (5).