carglumic acid carglumic acid carglumic acid, sold under the brand name carbaglu among others, is used for the treatment of hyperammonaemia. carglumic acidclinical datatrade namescarbaglu, ucedaneother names(s)-2-ureidopentanedioic acidahfs/drugs.commonographlicense data eu ema: by inn us dailymed: carglumic_acid pregnancycategory au: b1 routes ofadministrationby mouthatc codea16aa05 (who) legal statuslegal status au: s4 (prescription only) us: ℞-only eu: rx-only pharmacokinetic databioavailability30%protein bindingundeterminedmetabolismpartialelimination half-life4.3 to 9.5 hoursexcretionfecal (60%) and kidney (9%, unchanged)identifiers iupac name (2s)-2-(carbamoylamino)pentanedioic acid cas number1188-38-1 npubchem cid121396iuphar/bps7458drugbankdb06775 ychemspider1265942 n108351 nunii5l0hb4v1ewkeggd07130 ychebichebi:71028 nchemblchembl1201780 ncomptox dashboard (epa)dtxsid7046706 echa infocard100.116.323 chemical and physical dataformulac6h10n2o5molar mass190.155 g·mol−13d model (jsmol)interactive image smiles c(cc(=o)o)(c(=o)o)nc(=o)n inchi inchi=1s/c6h10n2o5/c7-6(13)8-3(5(11)12)1-2-4(9)10/h3h,1-2h2,(h,9,10)(h,11,12)(h3,7,8,13)/t3-/m0/s1 ykey:lcqlhjzyvoqkhu-vkhmyheasa-n y ny (what is this?) (verify) carglumic acid is a carbamoyl phosphate synthetase 1 (cps 1) activator. the most common adverse effects include vomiting, abdominal pain, pyrexia (fever), and tonsillitis, anemia, diarrhea, ear infection, other infections, nasopharyngitis, decreased hemoglobin levels, and headache. it was approved for medical use in the united states in march 2010. carglumic acid is an orphan drug. it is available as a generic medication. medical uses carglumic acid is indicated for the treatment of acute hyperammonemia and chronic hyperammonemia.