You will be given a definition of a task first, then some input of the task.
In this task, we ask you to elaborate the sentence without changing its general meaning. You can do so by explaining further the input sentence, using more precise wording, adding qualifiers and auxiliary information etc.

Many human genetic disorders come from splicing variants .
Output:
Abnormal variations in splicing are also implicated in disease ; a large proportion of human genetic disorders result from splicing variants .