Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Input: Consider Input: Ibuprofen-induced meningitis: detection of intrathecal IgG synthesis and immune complexes.

Output: adverse drug event


Input: Consider Input: This is the first reported case of suspected DIAN due to cefuroxime.

Output: adverse drug event


Input: Consider Input: These findings, together with increased urinary copper excretion and the absence of clinical improvement, are compatible with a generalized defect in copper metabolism, transport or storage.


Output: non-adverse drug event


