Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
--------
Question: At explant, all four systems had clots adherent to the surface of the tubing and connectors on the pump outflow side of the circuit.

Answer: non-adverse drug event


Question: INTRODUCTION: Despite high success rates with free-tissue transfer, flap loss continues to be a devastating event.

Answer: non-adverse drug event


Question: After positioning of a 0.035 inch guidewire proximal to the biliary stricture, the preloaded catheter was advanced over the guidewire by using the monorail technique.

Answer:
non-adverse drug event


