Part 1. Definition
Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Part 2. Example
A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Answer: adverse drug event
Explanation: Here, the child is facing some trouble after undergoing a particular therapy, thereby causing an adverse effect of the therapy.
Part 3. Exercise
Many clinicians appear to be concerned about the potential hepatotoxicity of the opiate antagonist naltrexone (NTX) and this may be one reason why it is not used more widely in treating both heroin and alcohol abusers.
Answer:
adverse drug event