Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Input: Consider Input: We believe that this is the first description of acute hepatitis caused by an idiosyncratic adverse reaction to gliclazide or to one of its metabolites.

Output: adverse drug event


Input: Consider Input: A case of acute cardiomyopathy and pericarditis associated with methylphenidate.

Output: adverse drug event


Input: Consider Input: This is particularly the case for children, who often exhibit resistance to intramuscular or rectal administration of drugs.


Output: non-adverse drug event


