Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Input: Consider Input: CASE DESCRIPTION: A 24-year-old 732-kg (1,610-lb) pregnant Belgian draft horse mare developed neuropathy and signs of intractable pain following colic surgery.

Output: non-adverse drug event


Input: Consider Input: Hypersensitivity reactions involving the kidneys can occur with any of the penicillin groups.

Output: non-adverse drug event


Input: Consider Input: Salicylate hepato toxicity in rheumatic fever.


Output: adverse drug event


