instruction:
Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
question:
OBJECTIVE: To report a case of marked elevation of serum creatine kinase (CK) associated with olanzapine therapy.
answer:
adverse drug event


question:
Imatinib mesylate therapy in patients with gastrointestinal stromal tumors and impaired liver function.
answer:
non-adverse drug event


question:
In a patient suffering from rheumatoid arthritis, we report the first simultaneous occurrence of two side effects of low-dose methotrexate: an acute megaloblastic anaemia and a pneumonitis.
answer:

adverse drug event


