Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Example Input: Three patients receiving gold salt treatment for rheumatoid arthritis developed severe aplastic anemia.
Example Output: adverse drug event

Example Input: Primary CNS lymphoma regressed on withdrawal of MM.
Example Output: adverse drug event

Example Input: Treatment with infliximab is known to produce an increase of autoantibodies (antinuclear antibodies, anti-double-stranded DNA), but not clinical disease.
Example Output:
adverse drug event

