Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
--------
Question: Unusual pigmentary changes associated with 5-fluorouracil therapy.

Answer: adverse drug event


Question: Graves' hyperthyroidism following transient thyrotoxicosis during interferon therapy for chronic hepatitis type C.

Answer: adverse drug event


Question: A case of recurrent impetigo herpetiformis with a positive family history.

Answer:
non-adverse drug event


