Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Ex Input:
Heavily in debt, Clinton lobbied the Duke of Newcastle for profitable employment as an American governor: he was appointed Governor of the Province of New York in July 1741 and arrived in New York in September 1743 to take up his position. Promoted to rear-admiral on 10 December 1743 and vice-admiral on 23 June 1744, he sought to protect New York's Northern border from attack by the French: however liberal members of the New York assembly resisted his proposals as they wanted to maintain trade links with the French and with the Native Americans who were under French influence. James De Lancey, who had initially been his main adviser, turned against him and sought to block the governor's salary. Clinton therefore invited Sir William Johnson to take over responsibility for Native American affairs in 1746 and appointed Cadwallader Colden to be his advisor. Clinton was promoted to full admiral on 15 July 1747. Working with the Mohawk chief Hendrick Theyanoguin, Johnson was able to recruit Mohawk warriors to fight on the side of the British in 1747 during King George's War. After continuing disputes with the assembly over military expenditure and payment of the governor's salary, Clinton resigned as governor in October 1753.

Ex Output:
What happened second: Clinton was appointed Governor or promoted to rear-admiral?


Ex Input:
The Gruffalo is a children's book by writer and playwright Julia Donaldson, illustrated by Axel Scheffler, that tells the story of a mouse, the protagonist of the book, taking a walk in a European forest.

Ex Output:
What person illustrated The Gruffalo?


Ex Input:
Protective protein/cathepsin A (PPCA) has a serine carboxypeptidase activity of unknown physiological function. We now demonstrate that this protease activity triggers the degradation of the lysosome-associated membrane protein type 2a (lamp2a), a receptor for chaperone-mediated autophagy (CMA). Degradation of lamp2a is important because its level in the lysosomal membrane is a rate-limiting step of CMA. Cells defective in PPCA show reduced rates of lamp2a degradation, higher levels of lamp2a and higher rates of CMA. Restoration of PPCA protease activity increases rates of lamp2a degradation, reduces levels of lysosomal lamp2a and reduces rates of CMA. PPCA associates with lamp2a on the lysosomal membrane and cleaves lamp2a near the boundary between the luminal and transmembrane domains. In addition to the well-studied role of PPCA in targeting and protecting two lysosomal glycosidases, we have defined a role for the proteolytic activity of this multifunctional protein.

Ex Output:

Which is the receptor for substrates of Chaperone Mediated Autophagy?


