In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.

 Stimulation of T lymphocytes results in a rapid increase in intracellular calcium concentration ( [ Ca2 + ] i ) that parallels the activation of Ca2 + - calmodulin - dependent protein kinase IV ( CaMKIV ) , a nuclear enzyme that can phosphorylate and activate the cyclic adenosine monophosphate ( cAMP ) response element - binding protein ( CREB ) .
nuclear enzyme

 Intense interest is focused on PPAR - gamma and its ligands owing to its putative role in adipocyte differentiation .
PPAR - gamma

 The mechanism of reducing NO production resulting from inhaled NO may involve , in part , the activities of reactive oxygen species and / or nuclear factor - kappaB .

nuclear factor

