instruction:
In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
question:
 Furthermore , suppression of Akt - 1 by inhibition of PI3K or a dominant negative ( DN ) Akt - 1 resulted in loss of mitochondrial transmembrane potential , activation of caspases - 9 and - 3 , and DNA fragmentation .
answer:
Akt - 1


question:
 Corresponding enzymatic activity was detectable only for 17 - hydroxysteroid dehydrogenase and 5alpha - reductase , respectively producing testosterone and 5alpha - dihydrotestosterone .
answer:
5alpha - reductase


question:
 A similar response was induced by endothelial stimulation with IL - 1beta , here used as positive control ( 195 + / - 20 cells / mm2 ) .
answer:

IL - 1beta


