In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.

[Q]:  Inhaled NO also blocked the activities of reactive oxygen species and nuclear factor - kappaB binding to DNA in lavage cells and in alveolar macrophages .
[A]: nuclear factor


[Q]:  Nevertheless , inhibitors of these pathways clearly reduced the TNF - alpha - induced cell growth , indicating that TNF - alpha - proliferative cells produced a growth factor that induced proliferation upon stimulation of the above pathways .
[A]: TNF - alpha


[Q]:  It induced NK cell - dependent rejection of tumors , but failed to stimulate systemic T cell - mediated anti - tumor immunity , and synergized with B7 - 1 - mediated immunotherapy to cause the NK cell and CD8 T cell - dependent rejection of larger EL - 4 tumors ( 0 . 4 cm in diameter ) that were refractory to monotherapies .
[A]:
B7 - 1


