instruction:
Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.
question:
Context: Ca2+ is a ubiquitous intracellular messenger responsible for controlling numerous cellular processes including fertilization, mitosis, neuronal transmission, contraction and relaxation of muscles, gene transcription, and cell death. At rest, the cytoplasmic Ca2+ concentration [Ca2+]i is approximately 100 nM, but this level rises to 500-1,000 nM upon activation. In osteoblasts, the elevation of [Ca2+]i is a result of an increase in the release of Ca2+ from endoplasmic reticulum and/or extracellular Ca2+ influx through voltage gated Ca2+ channels. Many of the cellular effects of Ca2+ are mediated by the Ca2+ binding protein, calmodulin (CaM). Upon binding up to four calcium ions, CaM undergoes a conformational change, which enables it to bind to specific proteins eliciting a specific response. Calmodulin kinase II (CaMKII) is a major target of the Ca(2+)/CaM second messenger system. Once bound to Ca(2+)/CaM, the multimeric CaMKII is released from its autoinhibitory status and maximally activated, which then leads to an intraholoenzyme autophosphorylation reaction. Calcineurin (Cn) is another major target protein that is activated by Ca(2+)/CaM. Cn is a serine-threonine phosphatase that consists of a heterodimeric protein complex composed of a catalytic subunit (CnA) and a regulatory subunit (CnB). Upon activation, Cn directly binds to, and dephosphorylates nuclear factor of activated T cells (NFAT) transcription factors within the cytoplasm allowing them to translocate to the nucleus and participate in the regulation of gene expression. This review will examine the potential mechanisms by which calcium, CaM, CaMKII, and Cn/NFAT control osteoblast proliferation and differentiation. 
 Question: Which calcium/calmodulin dependent protein phosphatase is involved in the activation of the family of NFAT transcription factors (Nuclear Factors of Activated T cells)?
answer:
can


question:
Context: Even while in a deep sleep, people can still learn brand new information. Sleepers soak in new associations between smells and sounds, knowledge that lingers into the next waking day, researchers report online August 26 in Nature Neuroscience. The new study is the first to show that entirely new information can get into the sleeping mind, says Anat Arzi of the Weizmann Institute of Science in Israel. "The brain is not passive while you sleep. It's quite active. You can do quite a lot of things while you are asleep." But the results don't mean that Spanish vocabulary tapes now have a place on the nightstand. L, Researchers have tried but largely failed to find evidence that complicated information, such as new pairs of words, can make its way into the brain during sleep. Instead of trying to teach people something complicated like a new language, Arzi and her colleagues relied on the sense of smell and hearing. As anyone who has walked by a dumpster in July knows, smells can cause a nose-jerk reaction. Catching a bad smell automatically makes people inhale less, reducing the size of the inhale. But scent of fresh bread causes a long, deep inhale., rzi and her team took advantage of this reaction for their experiment. As people slept in the laboratory, the researchers delivered pleasant scent, such as shampoo. As this nice smell got into the sleepers' noses, the researchers played a particular music. Later, a disgusting smell, such as rotten fish or meat, was paired with a different music. Neither the smell nor the sound woke people up. After just four exposures to the smell-music pair during a single night, the sleepers started to automatically respond to the tones without the accompanying smells, taking in bigger breaths when the shampoo-associated tone played and smaller breaths when played the sound linked to the rotten fish smell. This new learned association lingered into the next waking day, too. Even though the sleepers had no idea they had been exposed to smells or sounds, their behavior proved that their brain had actually learned something during sleep. As before, the shampoo sound stimulated a long, deep inhale, while the rotten fish tone caused more shallow breaths. 
 Question: In which part of a website may this passage most likely appear?
answer:
science.


question:
Context: Majda Mehmedovic (born 25 May 1990) is a Montenegrin handball player. 
 Question: What is Majda Mehmedovic's sport of choice?
answer:

handball


