Detailed Instructions: In this task, given a sentence in the English language, your task is to convert it into the Japanese language.
See one example below:
Problem: Test subjects will be administered either a placebo or PA-457 that will be taken in combination with the medication they already take.
Solution: 被験者は、彼らがすでに服用している薬剤と一緒に偽薬またはPA-457を与えられる。
Explanation: The above sentence is correctly translated from English to Japanese.

Problem: Mr Howard said the plan addresses issues which fall into its area of responsibility.
Solution:
ハワード氏は計画が責任の範囲に入る問題に対処すると言った。