Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
One example is below.
Q: In 1582 the united provinces invited francis, duke of anjou to lead them; but after a failed attempt to take antwerp in 1583, the duke left the netherlands again. after the assassination of william of orange (10 july 1584), both henry iii of france and elizabeth i of england declined the offer of sovereignty. however, the latter agreed to turn the united provinces into a protectorate of england (treaty of nonsuch, 1585), and sent the earl of leicester as governor-general. this was unsuccessful and in 1588 the provinces became a confederacy. the union of utrecht is regarded as the foundation of the republic of the seven united provinces, which was not recognized by the spanish empire until the peace of westphalia in 1648.
A: In what year did francis, duke of anjou leave the netherlands?
Rationale: The generated question is perfect. Because the question is based on second sentence of the input passage and its answer is 1583.
Q: Motherhood may make women smarter and may help prevent dementia in old age by bathing the brain in protective hormones , U.S.researchers reported on Thursday. Tests on rats show that those who raise two or more litters of pups do considerably better in tests of memory and skills than rats who have no babies, and their brains show changes that suggest they may be protected against diseases such as Alzheimer's .University of Richmond psychology professor Craig Kinsley believes his findings will translate into humans."Our research shows that the hormones of pregnancy are protecting the brain, including estrogen , which we know has many neuroprotective effects," Kinsley said. "It's rat data but humans are mammals just like these animals are mammals," he added in a telephone interview."They go through pregnancy and hormonal changes." Kinsley said he hoped public health officials and researchers will look to see if having had children protects a woman from Alzheimer's and other forms of age-related brain decline. "When people think about pregnancy, they think about what happens to babies and the mother from the neck down," said Kinsley, who presented his findings to the annual meeting of the Society of Neuroscience in Orlando, Florida. "They do not realize that hormones are washing on the brain.If you look at female animals that have never gone through pregnancy, they act differently toward young.But if she goes through pregnancy, she will sacrifice her life for her infant--that is a great change in her behavior that showed in genetic alterations to the brain."
A:
What can protect the brain of a woman according to the passage?