Instructions: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
Input: Question: In a patient with Renal Insufficiency, oral drugs must be administered: 
 Options:  <1> With natural fruit juices. <2> With the lowest volume of liquid possible. <3> With the same volume as any other patient. <4> With the largest volume of liquid possible. <5> Always during hemodialysis.
Output:
2