Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

[Q]: Several case reports of aplastic anemia with use of acetazolamide, and two cases with use of methazolamide, have appeared in the literature.
[A]: adverse drug event


[Q]: Two patients with extrinsic asthma and coexistent insulin-dependent diabetes mellitus sustained an anaphylactoid reaction after the intravenous administration of 50% solution of dextrose.
[A]: adverse drug event


[Q]: Power spectrum analysis of heart rate variability demonstrated marked abnormalities in autonomic nervous system activity.
[A]:
non-adverse drug event


