Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Ex Input:
All patients except two had new recurrences within the observation time.

Ex Output:
non-adverse drug event


Ex Input:
All patients improved rapidly after discontinuation of 5-ASA compounds.

Ex Output:
non-adverse drug event


Ex Input:
Generalized and partial complex seizures, other neurological signs and symptoms, and laboratory data were improved after modification of her anticonvulsant regimen.

Ex Output:

non-adverse drug event


