Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Example Input: Semiquantitative measurements of cytokine mRNA in his bronchoalveolar lavage cells prior to therapy with IFN-alpha revealed high levels of IL-4 and IL-10 mRNA, which decreased significantly with treatment.
Example Output: non-adverse drug event

Example Input: Ibuprofen-induced meningitis: detection of intrathecal IgG synthesis and immune complexes.
Example Output: adverse drug event

Example Input: Pilocarpine toxicity and the treatment of xerostomia.
Example Output:
adverse drug event

