Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Example Input: Imatinib mesylate therapy in patients with gastrointestinal stromal tumors and impaired liver function.
Example Output: non-adverse drug event

Example Input: Induction of systemic lupus erythematosus by interferon-gamma in a patient with rheumatoid arthritis.
Example Output: adverse drug event

Example Input: Of the four patients who responded to HU with an increase in total Hb, all reported symptomatic improvement and three have not required further transfusions.
Example Output:
adverse drug event

