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How to help someone 
Listen to your friends. 
These are the people you know the best, and who know you the best. If you and your friends are close, you should be able to talk to one another about problems or concerns without fear of judgment.
Additionally, when your friend suggests something is wrong, or he need your help, be paying attention for indirect signs. Your friend may not always say something is wrong directly, so look for signs that something might be off, such as missing events he normally attends or expressing concerns about things that he previously never worried about, like money.