Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

[Q]: CASE REPORT: A 64-year-old man was evaluated for chronic low-back pain after multiple spine surgeries.
[A]: non-adverse drug event


[Q]: Two patients are described who developed sensory neuropathy after the ingestion of 30.6 and 114 g metronidazole respectively.
[A]: adverse drug event


[Q]: In this case, it was suspected that a combination of cigarette smoking, pulmonary fibrosis, and low-dose methotrexate therapy might have promoted the development of lung cancer.
[A]:
adverse drug event


