Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Let me give you an example: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
The answer to this example can be: adverse drug event
Here is why: Here, the child is facing some trouble after undergoing a particular therapy, thereby causing an adverse effect of the therapy.

OK. solve this:
CONCLUSION: The new quinolone derivatives (levofloxacin, sparfloxacin, grepafloxacin, trovafloxacin, gatifloxacin and moxifloxacin), also called gyrase inhibitors, are known for their potential to cause central nervous system-related adverse effects, including headache, dizziness and insomnia.
Answer:
adverse drug event