See this dialog response. It has been demonstrated that a loss of INI1 expression can result in the “unmasking” of a nuclear export signal, resulting in the transport of tumor suppressor proteins out of the nucleus of the cell, thus favoring tumorigenesis. What came before?
Read the following conversation:
[a]. What is the treatment for Epithelioid sarcoma?.
[b]. SINE compounds prevent the transport of these tumor suppressor proteins out of the nucleus, allowing them to function normally and encourage apoptosis..
[a]. Do you know of any other treatments?.
[b]. Recently, researchers have observed a synergistic effect when using SINE compounds in combination with traditional chemotherapies (such as doxorubicin)..
[a]. Are there any other interesting aspects about this article?.
[b]. 