Q: It is not easy to space buttonholes exactly the same distance apart, and it is very difficult to cut them precisely the right size . The tiniest slip of the scissors will make the hole too large, and even one thread uncut will leave *it* too small.
Are "the hole" and "it" the same?
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A: yes


Q: James asked Robert for a favor but *he* refused.
Are "Robert" and "he" the same?
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A: yes


Q: Dr. Adams informed Kate that *she* had cancer and presented several options for future treatment.
Are "Dr. Adams" and "she" the same?
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A:
no