Write the response.  * What is the mechanism of action of Epoetin alfa?. * The authors provide several hypotheses for potential etiologies of this reduced mortality, but, given the known increase in thrombosis and increased benefit in trauma patients as well as marginal nonsignificant benefit (adjusted hazard ratio of 0.9) in surgery patients, it could be speculated that some of the benefit might be secondary to the procoagulant effect of erythropoetin.. * Are there any other interesting aspects about this article?. * 
Regardless, this study suggests further research may be necessary to see which critical care patients, if any, might benefit from administration of erythropoeitin.