In this task, you're given a passage, further information available on a particular linked term from the statement, and an answer term. Your job is to generate a question that can use the information provided to obtain the given answer. You should use the information on both passage and link information to create the question. Note that the answer to the question should be exactly the given answer, and if the answer is none, the answer to the question shouldn't be obtainable from the passage or linked information.

Passage: Duchenne muscular dystrophy (DMD) is caused when a mutation in the dystrophin gene changes the RNA so that it no longer codes for functional dystrophin protein. This usually happens due to a mutation that alters the reading frame of the RNA downstream of the mutation, so-called frameshift mutation. If an exon with an appropriate number of bases lies near the mutation, removing that exon can correct the downstream reading frame, restoring the production of partially functional dystrophin. This is the general strategy used in the design of exon-skipping oligonucleotides for DMD. As there are 79 exons in the longest splice form of the dystrophin transcript, many different oligonucleotides are needed to address the range of mutations present in the population of people with DMD.
 Link Information: none Answer: none
What does the acronym RNA stand for that is changed due to a mutation in the dystrophin gene?