In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Question: Regarding COPD, which one is FALSE? 
 Options:  <1> Smoking is the most important factor in the development of COPD. <2> Contrary to asthma, there is no inflammatory component. <3> The genetic factor to develop better documented COPD is the deficit of alpha1 antitrypsin. <4> Acropachies are not characteristic of COPD and their presence should suggest associated bronchiectasis or bronchopulmonary carcinoma. <5> Spirometrically, obstruction is detected by a FEV1 / FVC ratio of less than 0.70.
2