Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.

Q: Context: Alpha-synuclein(-syn) is the main protein component of Lewy bodies (LBs), that together with nigrostriatal dopamine neuron loss constitute typical pathological hallmarks of Parkinson's disease (PD). Glutamate N-methyl-d-aspartate receptor (NMDAR) abnormalities, peculiarly involving NR2B-containing NMDAR, have been observed in the brain of PD patients and in several experimental models of the disease. Recent findings, indicating that -syn can modulate NMDAR trafficking and function, suggest that this protein may be a pivotal regulator of NMDAR activity. Prompted by these evidences, we used fluorescence immunocytochemistry, western blotting and ratiometric Ca(2+) measurements to investigate whether wild type (wt) or C-terminally truncated -syn can specifically modulate NR2B-containing NMDAR levels, subcellular trafficking and function. In addition, we evaluated whether the exposure of primary cortical neurons to increasing concentrations of rotenone could differentially regulate NR2B levels and cell viability in the presence or in the absence of -syn. Our results indicate that both wt and C-terminally truncated -syn negatively modulate NR2B-containing NMDAR levels, membrane translocation and function. Moreover, we found that absence of -syn abolishes the rotenone-dependent decrease of NR2B levels and reduces neuronal vulnerability in primary cortical neurons. These findings suggest that -syn can modulate neuronal resilience by regulating NR2B-containing NMDAR, whose specific alterations could connect -syn pathology to neuronal degeneration in PD. 
 Question: Which is the primary protein component of Lewy bodies?

A: αsyn
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Q: Context: Energy, or the ability to do work, can exist in many different forms. The photo in Figure 17.8 represents six of the eight different forms of energy that are described in this lesson. The guitarist gets the energy he needs to perform from chemical energy in food. He uses mechanical energy to pluck the strings of the guitar. The stage lights use electrical energy and give off both light energy and thermal energy, commonly called heat. The guitar also uses electrical energy, and it produces sound energy when the guitarist plucks the strings. For an introduction to all these forms of energy, go to this URL: . For an interactive animation about the different forms of energy, visit this URL: After you read below about different forms of energy, you can check your knowledge by doing the drag and drop quiz at this URL: . Mechanical energy is the energy of an object that is moving or has the potential to move. It is the sum of an objects kinetic and potential energy. In Figure 17.9, the basketball has mechanical energy because it is moving. The arrow in the same figure has mechanical energy because it has the potential to move due to the elasticity of the bow. What are some other examples of mechanical energy? Energy is stored in the bonds between atoms that make up compounds. This energy is called chemical energy, and it is a form of potential energy. If the bonds between atoms are broken, the energy is released and can do work. The wood in the fireplace in Figure 17.10 has chemical energy. The energy is released as thermal energy when the wood burns. People and many other living things meet their energy needs with chemical energy stored in food. When food molecules are broken down, the energy is released and may be used to do work. Electrons are negatively charged particles in atoms. Moving electrons have a form of kinetic energy called electrical energy. If youve ever experienced an electric outage, then you know how hard it is to get by without electrical energy. Most of the electrical energy we use is produced by power plants and arrives in our homes through wires. Two other sources of electrical energy are pictured in Figure 17.11. The nuclei of atoms are held together by powerful forces. This gives them a tremendous amount of stored energy, called nuclear energy. The energy can be released and used to do work. This happens in nuclear power plants when nuclei fission, or split apart. It also happens in the sun and other stars when nuclei fuse, or join together. Some of the suns energy travels to Earth, where it warms the planet and provides the energy for photosynthesis (see Figure The atoms that make up matter are in constant motion, so they have kinetic energy. All that motion gives matter thermal energy. Thermal energy is defined as the total kinetic energy of all the atoms that make up an object. It depends on how fast the atoms are moving and how many atoms the object has. Therefore, an object with more mass has greater thermal energy than an object with less mass, even if their individual atoms are moving at the same speed. You can see an example of this in Figure 17.13. Energy that the sun and other stars release into space is called electromagnetic energy. This form of energy travels through space as electrical and magnetic waves. Electromagnetic energy is commonly called light. It includes visible light, as well as radio waves, microwaves, and X rays (Figure 17.14). The drummer in Figure 17.15 is hitting the drumheads with drumsticks. This causes the drumheads to vibrate. The vibrations pass to surrounding air particles and then from one air particle to another in a wave of energy called sound energy. We hear sound when the sound waves reach our ears. Sound energy can travel through air, water, and other substances, but not through empty space. Thats because the energy needs particles of matter to pass it on. Energy often changes from one form to another. For example, the mechanical energy of a moving drumstick changes to sound energy when it strikes the drumhead and causes it to vibrate. Any 
 Question: energy of an object that is moving or has the potential to move

A: mechanical energy
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Q: Context: In 1740, the Mon of Lower Burma revolted against the Toungoo Dynasty and founded the Restored Hanthawaddy Kingdom based in Pegu . Throughout the 1740s, the Hanthawaddy forces were winning against Upper Burma-based Toungoo armies. The Siamese were concerned by another rising power in Burma since a strong Burma historically meant future invasions to Siam. Concerned, the Siamese court readily gave protection to the Burmese governors of Martaban and Tavoy who had fled to Siam. In 1745, they sent a diplomatic mission to Ava to evaluate the political situation there, and were received by the Burmese king Mahadhammaraza Dipadi. They saw an Ava court that was on its last legs. By 1751, Restored Hanthawaddy forces were closing in on Ava. The Siamese concerns about the emergence of another strong dynasty based in Pegu appeared imminent. Perhaps as a precautionary measure, the Siamese decided to move their forward base into the upper coast in 1751. While it remains unclear as to whether the Siamese ever intended to go beyond the coast into mainland Lower Burma, the Siamese action nonetheless rang alarm bells in Pegu. Deeply concerned, the Hanthawaddy leadership withdrew two-thirds of their army back down to Lower Burma immediately after they had toppled the last Toungoo king in April 1752. This redeployment of Hanthawaddy troops proved a critical turning point in Burmese history as it gave nascent Upper Burmese resistance groups much needed breathing room. The Hanthawaddy command left less than 10,000 men to pacify all of Upper Burma. Taking advantage of light Hanthawaddy troops, one resistance group, the Konbaung Dynasty led by Alaungpaya, drove out Hanthawaddy troops from Upper Burma by May 1754. Konbaung armies invaded Lower Burma in 1755, and captured Pegu in 1757, ending the 17-year-old Mon kingdom. 
 Question: When were Hanthawaddy troops redeployed to lower Burma?

A:
april 1752
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