In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.

 These studies reveal that CREM , a tissue - specific factor , is expressed and regulated by gonadotropins in the ovary , that the predominant CREM transcripts encode the repressor protein ICER , and that ICER is capable of inhibiting cAMP - induced expression of the inhibin alpha - subunit gene .
repressor protein ICER