Given an abstract, indicate which of the provided candidate titles (Option1 and Option2) best describes it (respond with the text of the title, not option1/2).

[EX Q]: Abstract: Review of the literature reveals much disparity regarding the incidence, natural history, and survival rate in patients harboring esthesioneuroblastoma (olfactory neuroblastoma). The metastatic tendencies of this tumor have been highly variable in the literature, and reported intracranial involvement has been via local extension from the tumor's origin near the cribriform plate. Our present case describes a metastasis of esthesioneuroblastoma to the right parietal cortex and meninges in a patient without evidence of local recurrence after combined surgical and radiation therapy 5 years previously. The broad spectrum of biological behavior of this tumor, and its response to various therapies are discussed. The immunohistochemical and ultrastructural features of this unusual tumor are also presented. Recommendations are made for the management of these patients, including regular serial neurological examinations, serial computed axial tomography or magnetic resonance imaging of the head and neck, and, in the initial management, chemotherapy. 
 Which is the apt title for the abstract? option1: Late intracranial metastasis from esthesioneuroblastoma: case report and review of the literature. option2: Liver metastasis detection: comparative sensitivities of MR imaging and CT scanning.
[EX A]: Late intracranial metastasis from esthesioneuroblastoma: case report and review of the literature.

[EX Q]: Abstract: From February 1984 to March 1986, 28 patients underwent a new technique of coarctation repair. This technique consists of a complete mobilization of the left subclavian artery extended to the origin of its first branches. The aorta need not be extensively mobilized and the intercostal arteries are individually controlled with snares. After all the proper clamping, the left subclavian artery is detached from the aorta at its origin and is opened longitudinally on its posterior aspect. The anterior wall of the aorta is then incised, beginning with the opening at the origin of the left subclavian artery and extending distally to the descending aorta 12 to 15 mm past the coarctation. The coarctation membrane is excised and the ductus is ligated and divided. The opened left subclavian artery, now forming a flap, is pulled down and sutured to the edges of the aorta, widening the coarctation site and also preserving the blood flow to the left arm. The ages of the patients ranged from 2 months to 25 years (mean 4.24 +/- 4.9 years) and their weights ranged from 2.8 to 52 kg (mean: 14.8 +/- 10.0 kg). There were no hospital deaths and the mean follow-up was 9.6 months (+/- 4.9 months). Recatheterization of four patients from 4 to 12 months postoperatively showed adequate correction and strongly suggested normal growth of the aorta at the site of coarctation, as well as preservation of the blood flow through the left subclavian artery. Doppler measurements showed normal flow to the left arm and no gradients through the isthmic area. Our experience indicates that this technique is not only feasible but is the procedure of choice in most cases of discrete isthmic coarctation and in some cases of long narrowing of the isthmus in patients with a wide range of ages and weights. 
 Which is the apt title for the abstract? option1: A new technique for repair of aortic coarctation. Subclavian flap aortoplasty with preservation of arterial blood flow to the left arm. option2: Target-specific nerve regeneration through a nerve guide in the rat.
[EX A]: A new technique for repair of aortic coarctation. Subclavian flap aortoplasty with preservation of arterial blood flow to the left arm.

[EX Q]: Abstract: Thrombospondin with fibrinogen, fibronectin, and von Willebrand factor binds to platelets stimulated with agonists and support platelet adhesive functions. The receptors for the latter three proteins are associated with membrane glycoprotein GPIIb-IIIa. Thrombasthenic platelets deficient in GPIIb-IIIa have been utilized to examine the role of this membrane protein in the interactions of thrombospondin with platelets. Radioiodinated thrombospondin bound to thrombin-stimulated platelets from normal and thrombasthenic donors with a similar affinity and capacity. As monitored with a monoclonal antibody to thrombospondin, the divalent ion-dependent and -independent pathways for the expression of the endogenous pool of thrombospondin on the surface of thrombin-stimulated platelets from normal and thrombasthenic donors were also qualitatively and quantitatively similar. GPIIb-IIIa or ligands associated with GPIIb-IIIa thus are not essential for the binding of thrombospondin to platelets. Therefore, thrombospondin interacts with unique receptors on platelets. 
 Which is the apt title for the abstract? option1: Identification of a new class of inducible receptors on platelets. Thrombospondin interacts with platelets via a GPIIb-IIIa-independent mechanism. option2: Vacuolar encephalopathy of AIDS [letter]
[EX A]:
Identification of a new class of inducible receptors on platelets. Thrombospondin interacts with platelets via a GPIIb-IIIa-independent mechanism.

