Detailed Instructions: In this task, you are given a list of integers you need to calculate and return the range of the integers which is the difference between maximum and minimum element in the list.
Q: [294, 478, 112, 431, 387, 456, 125, 95, 341, 452, 103, 278, 28, 42, 172, 309, 235, 221, 381, 434]
A:
450