Detailed Instructions: This task involves creating questions from a given passage that involve some kind of complex reasoning (including numerical reasoning). 
The generated questions must require looking at more than one part of the passage to answer. Try to use a variety of reasoning types in your questions (some of the sample reasoning types are illustrated in the 'positive examples' field) and also have a variety of answer types (spans, numbers, dates). A span is a continuous phrase taken directly from the passage or question. In such questions, the answer spans are recommended to be five words. Questions with answer type "number", are expected to start with "How many". For instance, "How long did an event last?" can be phrased as "How many years did an event last?". To increase diversity, try to create more questions for which the answer will be multiple spans. Please create questions that require AT LEAST 2 arithmetic operations as illustrated in the 'positive examples' field. You are encouraged to try DIFFERENT COMBINATIONS of operations and not just limit to the combinations shown in those examples. The more challenging questions you create, the better it is.
Problem:Passage: Gabapentin at a low dose of 100 mg has a Tmax (pharmacology) (time to Cmax (pharmacology)) of approximately 1.7 hours, while the Tmax increases to 3 to 4 hours at higher doses. Food does not significantly affect the Tmax of gabapentin and increases the Cmax of gabapentin by approximately 10%. The Tmax of the modified-release dosage (medicine) (IR) formulation of gabapentin enacarbil (as active gabapentin) is about 2.1 to 2.6 hours across all doses (350-2,800 mg) with single administration and 1.6 to 1.9 hours across all doses (350-2,100 mg) with repeated administration. Conversely, the Tmax of the modified-release dosage (medicine) (XR) formulation of gabapentin enacarbil is about 5.1 hours at a single dose of 1,200 mg in a fasted state and 8.4 hours at a single dose of 1,200 mg in a fed state.
Solution:
How many hour can pass while taking 350-2800 mg of Gabapentin for all doses?