Instructions: In this task, you are given a question and answer options for that question. Using this information, you have to classify each text into different topics: medicine, nursery, psychology, chemistry, pharmacology, biology.
Input: Question: What factors depends on the apparent volume of distribution of a drug ?: 
 Options:  <0> Its degree of binding to plasma and tissue proteins and its elimination half-life. <1> Of its distribution coefficient and its elimination half-life. <2> Of its elimination half-life and its elimination constant. <3> Its degree of binding to plasma and tissue proteins and their distribution coefficient. <4> Of its constant elimination and its clearing.
Output:
medicine