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How to prevent botulism in horses 
Get your horse vaccinated against a botulism infection. 
Ask your vet to administer a type-b toxoid vaccine to protect your horse. Although it doesn't protect against all forms of botulism, it limits your horse's risk of contracting the illness.
The vaccine can be administered at any time after the horse is at least 2 weeks old. Vaccination involves 3 initial dose vaccinations, followed by a single annual booster vaccination.