Coming back to Toronto with a 3–3 record over their road trip, the Blue Jays battled the last-place Los Angeles Angels of Anaheim for the first time in 2016. R.A. Dickey held the Angels to a single run over 6 innings, leading Toronto to a 7–2 win.
The preceding conversation:
2-way dialog:
 P1) What happened in the 2016 season with the Toronto Blue Jays?.
 P2) In the second game, the Blue Jays again took a one run lead into the ninth inning, however this time Osuna would close the game without issue, leading the Jays to a 6–5 win..
 P1) What happened with Aaron Loup?.
 P2) Prior to the series finale, the Blue Jays optioned Aaron Sanchez to the Advanced-A Dunedin Blue Jays to skip his next start, limit his innings, and allow his roster space to be used by Aaron Loup..
 P1) What happened with Brett Cecil?.
 P2) Brett Cecil would be called upon to pitch the eighth inning of the finale, and protect a 2–1 lead..
 P1) Are there any other interesting aspects about this article?.
 P2) Cecil would allow a two-run home run to José Ramírez that gave the Indians a 3–2 lead they would not relinquish..
 P1) What happened with the Angels?.
 P2) 