no
Question and rationale: The question is: Did the first Duke of Valentinois play a key role in the Hundred Years' War?
The Hundred Years' War was a conflict between England and France from 1337-1453. Cesare Borgia, the son of Pope Alexander VI, was the first Duke of Valentinois. Cesare Borgia was born in 1475.

yes
Question and rationale: The question is: Does autopilot rely on fossil fuels?
Autopilot is used in vehicles. Vehicles are powered by engines. Engines rely on fossil fuels to operate.

no
Question and rationale:
The question is: Did Bruiser Brody wrestle on WWE Raw?
WWE Raw debuted on TV January 11, 1993. Bruiser Brody was a wrestler that was stabbed to death in 1988.