input question: What is the question to: "Vascular ischemia of the toes with characteristic cyanosis ."? The topic is Ischemia.???
output answer: "What is Ischemia or infarction??"


What is the question to: "A point guard from St. John's University , he played for the New York Knicks , Indiana Pacers , Los Angeles Clippers , Denver Nuggets , Toronto Raptors , Utah Jazz and Houston Rockets in the NBA in a career spanning from 1987 to 2004."? The topic is Mark Jackson (basketball).
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Answer: "where did mark jackson play pro basketball??"


Q: What is the question to: "Over one million Jewish children were killed in the Holocaust, as were approximately two million Jewish women and three million Jewish men."? The topic is The Holocaust.
A: "how many people were killed in the holocaust?"


Question: What is the question to: "The Northern Cardinal (Cardinalis cardinalis) is a North American bird in the genus Cardinalis ; it is also known colloquially as the redbird or common cardinal."? The topic is Northern Cardinal.
Answer: "what is the scientific name of a cardinal bird?"


[Q]: What is the question to: "Black pepper (Piper nigrum) is a flowering vine in the family Piperaceae , cultivated for its fruit , which is usually dried and used as a spice and seasoning ."? The topic is Black pepper.
****
[A]: "how does black pepper grow?"


Problem: Given the question: What is the question to: "Due to Madden's insistence that the game be as realistic as possible, the first version of John Madden Football was not released until 1988."? The topic is Madden NFL.
++++++++++++++++++++++++++++++++
The answer is:

"when was the first nfl madden game released?"