Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Q: Abi Curtis received a PhD in Creative and Critical Writing from the University of Sussex, and went on to teach there until 2010.

A: Where did Abi Curtis study or work?
****
Q: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers worldwide. Despite significant progresses in the last decades, the origin of this cancer remains unclear and no efficient therapy exists. PDAC does not arise de novo: three remarkable different types of pancreatic lesions can evolve towards pancreatic cancer. These precursor lesions include: Pancreatic intraepithelial neoplasia (PanIN) that are microscopic lesions of the pancreas, Intraductal Papillary Mucinous Neoplasms (IPMN) and Mucinous Cystic Neoplasms (MCN) that are both macroscopic lesions. However, the cellular origin of these lesions is still a matter of debate. Classically, neoplasm initiation or progression is driven by several genetic and epigenetic alterations. The aim of this review is to assemble the current information on genetic mutations and epigenetic disorders that affect genes during pancreatic carcinogenesis. We will further discuss the interest of the genetic and epigenetic alterations for the diagnosis and prognosis of PDAC. Large genetic alterations (chromosomal deletion/amplification) and single point mutations are well described for carcinogenesis inducers. Mutations classically occur within key regions of the genome. Consequences are various and include activation of mitogenic pathways or silencing of apoptotic processes. Alterations of K-RAS, P16 and DPC4 genes are frequently observed in PDAC samples and have been described to arise gradually during carcinogenesis. DNA methylation is an epigenetic process involved in imprinting and X chromosome inactivation. Alteration of DNA methylation patterns leads to deregulation of gene expression, in the absence of mutation. Both genetic and epigenetic events influence genes and non-coding RNA expression, with dramatic effects on proliferation, survival and invasion. Besides improvement in our fundamental understanding of PDAC development, highlighting the molecular alterations that occur in pancreatic carcinogenesis could provide new clinical tools for early diagnosis of PDAC and the molecular basis for the development of new effective therapies.

A: Which is the molecular mechanism underlying K-ras alterations in carcinomas?
****
Q: The Packers' offense struggled for the first half against the Seahawks. On the Packers' first drive, Aaron Rodgers threw an interception that was returned for a touchdown, but an illegal block in the back penalty negated the score. Before that play Rodgers had gone his previous 251 regular season pass attempts without an interception, a career high. The Packers' defense held Seattle in check but trailed 3-0 at halftime. In the third quarter, Mike Daniels forced a fumble that Green Bay recovered at the Seattle 6-yard line, and Ty Montgomery ran in for a touchdown on the following play, giving the Packers a lead they wouldn't relinquish after that. Later Rodgers caught the Seahawks with 12 men on the field and capitalized on the free play by throwing a 32-yard touchdown to Jordy Nelson. The Packers only surrendered two field goals to Seattle for the rest of the game, giving a strong defensive showing in the season opener.

A:
Who scored the last touchdown of the game?
****
