Given a passage and a query based on the passage, generate an unambiguous, concise and simple answer to the query from information in the passage. Note that the answer may not be present in exact form.

Almond Milk/Coconut Milk Creamer - What does it mean that this is an “all natural” creamer? natural bliss® is an all-natural coffee creamer proudly made with no GMO ingredients. Our almond milk and coconut milk creamer products are made only with all natural ingredients. Our natural flavors come real food ingredients like vanilla flavor from Madagascar or coconuts sourced from Sumatra. Learn more about our different flavors and types of creamers. Transform your everyday coffee into something extraordinary. Learn more about our different flavors and types of creamers. • Coffee-mate® liquid should be used within 14 days after opening or before the use-by date, whichever comes first. • Coffee-mate® powder should be used by the use-by dates found on the packaging. Unopened, Coffee-mate® powder has a shelf-life of up to 24 months. It will not. natural bliss® is a dairy coffee creamer and Coffee-mate® is a non-dairy creamer. We will continue to make both for you to enjoy. Dairy - How can I find natural bliss® at a store near me? Depending on if they are non-dairy or liquid. Non-dairy up to two years. The liquid creamer only lasts a few months. The package should have an expiration date. Cold Brew Coffee - How long does natural bliss® brew/steep their Cold Brew Coffee? Our Cold Brew Coffee is steeped in cool water for 12hrs resulting in a smooth, bold flavor. Cold Brew Coffee - What is the caffeine content of natural bliss® Cold Brew? • Coffee-mate® liquid products found in the refrigerated case must be refrigerated at all times, before and after opening. • Only Coffee-mate® liquid products that are clearly marked “Refrigerate After Opening” may be stored in a dry, cool place before opening, but must be refrigerated after opening. Pour a little dessert into your cup and enjoy new Coffee-mate The Cheesecake Factory at Home™ flavors. Stir Up Sweetness Depends. If they're the non-dairy creamer, it can last for up to two years. The little pots of half and half are only good for a few months. Coffee-mate ® Turn the coffee you like into coffee you love. Find your Flavor natural bliss ® A new world of flavors made with natural ingredients. Discover Bliss ® Query: how long does powder creamer last
A Coffee-mate powder creamer has a shelf-life of up to 24 months.

Two known chemotherapy agents effectively target breast cancer stem cells Date: May 2, 2016 Source: Medical College of Georgia at Augusta University Summary: Two existing chemotherapy drugs appear to be a powerful pair in targeting errant stem cells that are making breast cancer and enabling its spread and recurrence, scientists report. Share: Chemotherapy targets cancer cells through similar biological processes. For instance, early chemotherapy drugs attacked folate, which is a key component of cellular division. Since cancer cells divide more than normal cells, they are more greatly harmed by this drug. Newer chemotherapy agents target specific mutations in certain cancer cells, making their effects very specific to only the tumor. To your last point, radiation and chemo both can induce future cancers. Radiation therapy targets cancer cells in two ways. First, we shape the beam of radiation such that it conforms as closely as possible to the shape of the tumor. We also treat from multiple different angles, with all beams converging on the tumor. Best Answer: The short answer is that they don't differentiate between cell types. This is why there are side effects. There are a variety of different mechanisms that the chemo meds employ, down-regulating certain proteins from being made, binding certain receptors to trigger cell death, etc. You hit it when you said the chemo meds mostly target rapidly dividing cells (or highly metabolically active cells.) And we're able to be relatively tissue specific too, so different drugs have affinities for different tissues. (That's why chemo for lung cancer and chemo for prostate cancer, for example, are very different protocols.) And the more we learn about how cancer cells work in the body, the more we're able to develop new tools to address them. How Cancer Stem Cells Thrive When Oxygen Is Scarce. 1  Mar. 28, 2016 — Working with human breast cancer cells and mice, scientists say new experiments explain how certain cancer stem cells thrive in low oxygen conditions. Proliferation of such cells, which tend to ... Two known chemotherapy agents effectively target breast cancer stem cells. https://www.sciencedaily.com/releases/2016/05/160502131417.htm. Two existing chemotherapy drugs appear to be a powerful pair in targeting errant stem cells that are making breast cancer and enabling its spread and recurrence, scientists report. Your source for the latest research news Most current chemotherapy does not kill the stem cells, which are the cells of origin, only the tumor mass, said Dr. Muthusamy Thangaraju, biochemist in the Department of Biochemistry and Molecular Biology at the Medical College of Georgia and Georgia Cancer Center at Augusta University. Features. 1  Book List. 2  Mods' Choice: Outstanding posts recognized by the mod team. 3  Weekly Features: Archives of AskAnything Wednesday, FAQ Fridays, and more! 4  FAQ: In-depth answers to many popular questions. 5  New and gilded posts. / 6 r/AskScienceDiscussion: For open-ended and hypothetical questions. Their work was done in mouse models of breast cancer, and findings held up in a human breast cancer cell line. The studies also provided more evidence -- at least in their animal models -- of why the stem cells are an important target. Normally, stem cells make progenitor cells, which make specific cells that comprise the breast. In this sense, the tumor is targeted geometrically - the radiation is aimed at the tumor, and not normal tissue. Secondly, cancer cells are more sensitive to radiation damage. Since they move through the cell cycle so rapidly, they are more likely to be in a specific, radiosensitive phase of cellular activity. Query: how does chemotherapy target cancer cells
Chemotherapy targets cancer cells through similar biological processes. For instance, early chemotherapy drugs attacked folate, which is a key component of cellular division. Since cancer cells divide more than normal cells, they are more greatly harmed by this drug.

for children 10 years and older, and adults (including seniors) is 60 - 100 beats per minute; for well-trained athletes is 40 - 60 beats per minute. Hittin’ the Target. Now you’re ready to determine your target training heart rate. As you exercise, periodically: Take your pulse on the inside of your wrist, on the thumb side. For most of us, between 60 and 100 beats per minute (bpm) is normal. 1 The rate can be affected by factors like stress, anxiety, hormones, medication, and how physically active you are. An athlete or more active person may have a resting heart rate as low as 40 beats per minute. Now that’s chill! When it comes to resting heart rate, lower is better. 150 beats per minute Important Note: A few high blood pressure medications lower the maximum heart rate and thus the target zone rate. If you're taking such medicine, call your physician to find out if you need to use a lower target heart rate. Use the tips of your first two fingers (not your thumb) to press lightly over the blood vessels on your wrist. Count your pulse for 10 seconds and multiply by 6 to find your beats per minute. You want to stay between 50 percent to 85 percent of your maximum heart rate. This range is your target heart rate. Know Your Numbers. This table shows estimated target heart rates for different ages. Your maximum heart rate is about 220 minus your age. Count your pulse for 30 seconds and multiply by 2 to find your beats per minute. Important Note: Some drugs and medications affect heart rate, meaning you may have a lower maximum heart rate and target zone. Before you learn how to calculate and monitor your target training heart rate, you have to know your resting heart rate. Your resting heart rate is the number of times your heart beats per minute while it’s at rest. You can check it in the morning after you’ve had a good night’s sleep and before you get out of bed. According to the National Institute of Health, the average resting heart rate: 1  for children 10 years and older, and adults (including seniors) is 60 - 100 beats per minute. 2  for well-trained athletes is 40 - 60 beats per minute. Your resting heart rate is the number of times your heart beats per minute when you’re at rest. A good time to check it is in the morning after you’ve had a good night’s sleep, before you get out of bed or grab that first cup of java! The easiest way to do this is to use a generic formula meant for the average person. For men, your maximum heart rate can be estimated by subtracting your age in years from 220. For example, a 20-year-old man would have a maximum heart rate of 200 beats per minute. For women, a newer standard is to take 88 percent of your age and subtract it from 206. Beats Per Minute in Exercise. The speed of your heart rate depends on the intensity of exercise that you wish to work at. The American Heart Association recommends exercising somewhere between 50 to 85 percent of your maximum. Beginners should start at the low end of this range and work up as fitness levels improve. There are three general ways to classify heart rate, 1) normal, 2) fast and 3) slow. A resting heart rate is normal between 60-100 beats per minute. A resting heart rate is fast (i.e. tachycardic) at greater than 100 beats per minute. A resting heart rate is slow (i.e. bradycardic) at less than 60 beats per minute. Beats Per Minute in Exercise The speed of your heart rate depends on the intensity of exercise that you wish to work at. The American Heart Association recommends exercising somewhere between 50 to 85 percent of your maximum. Query: average beats per minute/while exercising

For men, your maximum heart beats are 220 per minute and for women 206 while exercising.

