Answer the question from the given passage. Your answer should be directly extracted from the passage, and it should be a single entity, name, or number, not a sentence.

Passage: Anti-inflammatory drugs are often used to control the effects of inflammation. Glucocorticoids are the most powerful of these drugs; however, these drugs can have many undesirable side effects, such as central obesity, hyperglycemia, osteoporosis, and their use must be tightly controlled. Lower doses of anti-inflammatory drugs are often used in conjunction with cytotoxic or immunosuppressive drugs such as methotrexate or azathioprine. Cytotoxic drugs inhibit the immune response by killing dividing cells such as activated T cells. However, the killing is indiscriminate and other constantly dividing cells and their organs are affected, which causes toxic side effects. Immunosuppressive drugs such as cyclosporin prevent T cells from responding to signals correctly by inhibiting signal transduction pathways. Question: What are the most powerful class of anti-inflammatory drugs?
Glucocorticoids

Passage: 'The Islamic State', formerly known as the 'Islamic State of Iraq and the Levant' and before that as the 'Islamic State of Iraq', (and called the acronym Daesh by its many detractors), is a Wahhabi/Salafi jihadist extremist militant group which is led by and mainly composed of Sunni Arabs from Iraq and Syria. In 2014, the group proclaimed itself a caliphate, with religious, political and military authority over all Muslims worldwide. As of March 2015[update], it had control over territory occupied by ten million people in Iraq and Syria, and has nominal control over small areas of Libya, Nigeria and Afghanistan. (While a self-described state, it lacks international recognition.) The group also operates or has affiliates in other parts of the world, including North Africa and South Asia. Question: How many people did the Islamic State control the territory of as of March 2015?
ten million

Passage: Southern California consists of a heavily developed urban environment, home to some of the largest urban areas in the state, along with vast areas that have been left undeveloped. It is the third most populated megalopolis in the United States, after the Great Lakes Megalopolis and the Northeastern megalopolis. Much of southern California is famous for its large, spread-out, suburban communities and use of automobiles and highways. The dominant areas are Los Angeles, Orange County, San Diego, and Riverside-San Bernardino, each of which is the center of its respective metropolitan area, composed of numerous smaller cities and communities. The urban area is also host to an international metropolitan region in the form of San Diego–Tijuana, created by the urban area spilling over into Baja California. Question: Where does southern California's megalopolis standard in terms of population nationwide?

third

