instruction:
Given a paragraph, generate a claim that is supported by the given paragraph. 1) The claim must contain information from within the paragraph. 2) A sentence within the paragraph can be used as a claim. 3) The claim should not have contradictions within the paragraph. 4) The claim should be at most one sentence long.
question:
Although this therapy is not yet available for patient use, the story makes a point of noting that the cost may well be “stratospheric,” should it make it to market. If approved, such treatments are expected to command stratospheric prices. For example, a separate Spark gene therapy for a rare type of childhood blindness, which is on track for Food and Drug Administration clearance soon, could cost $1 million per patient for infusions in both eyes, according to some Wall Street analysts. Still, the therapies can produce at least some offsetting savings. Porteus noted in his editorial that the hemophilia therapy resulted in savings of about $200,000 a year per patient because of the elimination of clotting-factor infusions. The story summarizes the outcome of the small, 10-person trial that dominates this narrative: Lindsey George, the lead investigator and a hematologist at Children’s Hospital of Philadelphia, said that nine of the 10 men in the trial didn’t experience any bleeding episodes after the gene therapy treatment. The one patient who needed clotting factor because of bleeding used 91 percent less than before, she said. Although the story does not address harms directly–and should have–it does note that one of the worrying side effects of gene therapy—spurring the body to attack itself—was not present in this study. It is clear from the story that the study is small and an “early-stage trial.” One source also notes that the researchers tracked individuals in the study for no more than a year and a half, making longer term assessments unavailable. The story could have done more, though, to signal to the reader that, despite the encouraging outcomes of the study, the treatment is still very much under development. The next stage—Phase 3 trials—requires more participants, more careful study design, and takes, on average, three years to complete. The treatment described here, if ultimately proved worthy, could have a profound impact on a serious genetic condition. Independent sources are identified in the story, as are the funders. But missing from the text is information describing linkages between the two funders—Spark Therapeutics and Pfizer—and the lead researchers. It’s not clear from the story that there is a financial relationship. Individuals coping with hemophilia B have few options, and the story describes the main one: injections of blood-clotting factor to stem runaway bleeding. Since the story notes that the research is at an early stage with only 10 participants, a reader can easily infer that the treatment is not yet available. However, additional information about remaining evaluation stages for this treatment would have been a useful reinforcing addition. Hemophilia B sufferers who see this story will likely be contacting their doctors. The story establishes novelty with this: The researchers presented earlier findings on the gene therapy a year ago at the American Society of Hematology’s annual meeting, but the latest data covers a larger patient group and a longer time period. A news release issued by Children’s Hospital of Philadelphia did a good job of describing this study; the Post story could have picked up more of the salient details from that text but reveals independent reporting nevertheless by including sources not connected to the study.
answer:
Gene therapy makes a big advance treating hemophilia B blood disorder


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Dr. Denis Mukwege spoke Sunday at a news conference with Nadia Murad of Iraq, with whom he shared the 9-million Swedish kronor ($1 million) prize. Mukwege was honored for his work helping sexually abused women at the hospital he founded in the Democratic Republic of Congo. Murad, a Yazidi, won for her advocacy for sex abuse victims after being kidnapped by Islamic State militants. “What we see during armed conflicts is that women’s bodies become battlefields and this cannot be acceptable during our time,” Mukwege said, speaking through a translator. “We cannot only denounce it, we now need to act.” Murad, 25, was one of an estimated 3,000 girls and women from Iraq’s Yazidi minority group who were kidnapped in 2014 by IS militants and sold into sexual slavery. She was raped, beaten and tortured before managing to escape three months later. After getting treatment in Germany, she chose to speak to the world about the horrors faced by Yazidi women, despite regardless of the heavy stigma in her culture surrounding rape. She said Sunday it was difficult “for a girl, a woman, to rise up to say that these atrocities have happened.” Mukwege, a 63-year-old surgeon, founded a hospital in the city of Bukavu and over the past 20 years has treated countless women who were raped amid fighting between armed groups seeking to control of some the central African nation’s vast mineral wealth. He expressed concern Sunday that new violence could be coming as Congo holds a general election this month. “We think the conflict might blow up around this electoral period and women and children are always the first victims of such conflicts,” he said. Along with preventing sexual violence, more effort is needed to attend to victims, Mukwege said. “We need to realize that any woman who is a victim of sexual violence within her own country — such women should be allowed treatment and it’s not only medical treatment, also psychological treatment, judicial treatment,” he said. Murad said the psychological burden of her ordeal and her subsequent work is heavy. “I don’t want to live in fear. For the last four years I have been in Germany, in a safe place, but yet I’m living frightfully,” she said. “I’m scared that these people will not just attack me or have an impact on me, but with anybody else.” Murad and Mukwege will receive their prize Monday at a ceremony in the Norwegian capital. The winners of Nobel prizes for medicine, physics, chemistry and economics will get their prizes Monday in Stockholm. No Nobel literature winner was named this year due to turmoil in the Swedish Academy, which chooses the literature winners. ___ Jim Heintz in Moscow contributed to this story
answer:
Nobel peace winners demand action against sex abuse.


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Tedros Adhanom Ghebreyesus was speaking Monday at the start of the World Health Organization’s annual assembly, where issues like anti-microbial resistance, universal health care and WHO reform are among the topics up for discussion. Ghebreyesus noted that the current Ebola outbreak, which is the second deadliest on record and has been confirmed to have taken nearly 1,100 lives, is so far contained to two provinces of eastern Congo that are wracked by violence by armed groups. He said the outbreak was “one of the most complex health emergencies any of us have ever faced.”
answer:

UN health chief warns of ‘very high’ risk of Ebola spread.


