The Blues expect both Curnow and Marchbank to return in round eight.

"While unavoidable, these injuries are disappointing for Charlie, Caleb and the club as we prepare for our clash against Adelaide on Saturday night," Carlton's head of football Andrew McKay said.

"Clearly it’s less than ideal to have a number of our players out injured at the moment, however we’re very hopeful both players will be available for our game next weekend against Essendon."

Ruckman Matthew Kreuzer has come up for this week's game, while the Blues remain hopeful captain Marc Murphy could be fit to return in one to two weeks.

The Blues have had a poor run with injuries this season. Skipper Murphy was struck down by a plantar fascia injury just minutes before the Blues were set to take on North Melbourne in Tasmania. Kreuzer has missed the past two matches with a groin injury, while he and recruit Matthew Kennedy also missed games earlier in the year.