Addition from acquisitions

  
11. Property, plant and equipmentProperty, plant and equipment consisted of the following (dollar amounts in millions):

|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  | December 31, |
|  | Useful life (in years) |  | 2021 |  | 2020 |
| Land | — |  | $ | 279  |  |  | $ | 259  |  |
| Buildings and improvements | 10-40 |  | 4,028  |  |  | 3,857  |  |
| Manufacturing equipment | 8-12 |  | 3,080  |  |  | 2,865  |  |
| Laboratory equipment | 8-12 |  | 1,193  |  |  | 1,257  |  |
| Fixed equipment | 12 |  | 2,402  |  |  | 2,406  |  |
| Capitalized software | 3-5 |  | 1,151  |  |  | 1,216  |  |
| Other | 5-10 |  | 862  |  |  | 1,091  |  |
| Construction in progress | — |  | 987  |  |  | 915  |  |
| Property, plant and equipment, gross |  |  | 13,982  |  |  | 13,866  |  |
| Less accumulated depreciation and amortization |  |  | (8,798) |  |  | (8,977) |  |
| Property, plant and equipment, net |  |  | $ | 5,184  |  |  | $ | 4,889  |  |

During the years ended December 31, 2021, 2020 and 2019, we recognized depreciation and amortization expense associated with our property, plant and equipment of $644 million, $640 million and $635 million, respectively.Geographic informationCertain geographic information with respect to property, plant and equipment, net (long-lived assets), was as follows (in millions):

|  |  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
|  |  |  |  |  |  |  |  |  |  |  |  |
|   | December 31, |
|   | 2021 |  | 2020 |
| United States | $ | 2,801  |  |  | $ | 2,473  |  |
| Puerto Rico | 1,311  |  |  | 1,331  |  |
| ROW | 1,072  |  |  | 1,085  |  |
| Total property, plant and equipment, net | $ | 5,184  |  |  | $ | 4,889  |  |

12. Goodwill and other intangible assetsGoodwillThe changes in the carrying amounts of goodwill were as follows (in millions):

|  |  |  |  |  |  |  |  |  |  |  |  |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
|  |  |  |  |  |  |  |  |  |  |  |  |
|  | December 31, |
|  | 2021 |  | 2020 |
| Beginning balance | $ | 14,689  |  |  | $ | 14,703  |  |
| Addition from acquisitions | 251  |  |  | —  |  |
| Currency translation adjustments | (50) |  |  | (14) |  |
| Ending balance | $ | 14,890  |  |  | $ | 14,689  |  |

F-29
