What is the percentage change in the accounts payable and accrued expenses between 2018 and 2019?
{"Accounting": {"December 31, 2019": 36161, "December 31, 2018": 52365}, "Research and development": {"December 31, 2019": 650584, "December 31, 2018": 137114}, "Legal": {"December 31, 2019": 15273, "December 31, 2018": 32161}, "Other": {"December 31, 2019": 163029, "December 31, 2018": 10048}, "Total": {"December 31, 2019": 865047, "December 31, 2018": 231688}}
total_2019 = df["Total"]["December 31, 2019"]
total_2018 = df["Total"]["December 31, 2018"]
answer = (total_2019 - total_2018) / total_2018 * 100.0