In-vitro experiments were made to compare specific binding of 3H-diazepam with synaptic membranes obtained from the large hemispheres of rats trained the defense conditioned reflex to that in rats exposed to non-combined stimuli (active control). Within the concentration range of 0.37 nM-30 nM, specific binding of 3H-diazepam with the synaptic membranes obtained from the brain of active control animals was considerably higher than that with the synaptic membranes obtained from the trained animals brain.
Animals Avoidance Learning