The findings of normal testosterone, high normal delta 4 androstenedione, normal 17 OH progesterone and raised DHAs in a young girl of 16 who had regular periods and hirsutism made us think of block in 3 HSD. The 17 OH pregnenolone was raised. Dexamethasone (0.5 mg/24 h) treatment was effective for the hirsutism.
3-Hydroxysteroid Dehydrogenases Adolescent