The incidence of pleomorphic carcinoma of the pancreas is low. In 34 cases of non-endocrinic cancer of the pancreas detected pathologically by operation and autopsy in our hospital from 1961 to 1984, 3 were pleomorphic carcinoma, comprising 8.8%. In histology, the tumor was clearly characterized by the bizarre uninuclear and multinuclear giant cells with abundant eosinophilic cytoplasm and malignant spindle cells. In these 3 cases, the tumor was originated from the acinic epithelium in 2 and from the ductal epithelium in 1. This tumor should be differentiated from pleomorphic rhabdomyosarcoma, liposarcoma, fibrosarcoma and lymphosarcoma, etc.
Adult Carcinoma