BACKGROUND: Rupture premature of membranes occurs in 8% of all births constituting one of main causes of prematurity.OBJECTIVE: Determine qualitatively the presence of human chorionic gonadotropin hormone in vagina and used as diagnostic test to rupture of membranes.PATIENTS AND METHOD: We performed a study of diagnostic test observational, transverse, comparative, prospective, not blind type; in 175 healthy pregnant woman with 20 to 42 weeks of gestation, with suspicion of vaginal liquid outlet, at the Obstetrics Department Academic Hospital "Dr Jose Eleuterio Gonzalez" during the period of April 2009 to June 2011, crystallography and vaginal human chorionic gonadotropin hormone test were performed.RESULTS: We analyzed 175 patients, average age was 22.35 years old, was obtained sensibility and specificity of 98.90% y 77.38% to crystallography and 93.41% y 73.81% to vaginal human chorionic gonadotropin hormone test, with value positive predictive of 79.44% and value negative predictive of 91.18% for this last.CONCLUSIONS: Determine qualitatively the presence of human chorionic gonadotropin hormone in vagina is a diagnostic test useful for detecting premature rupture of membranes has been shown to be as effective as crystallography.
Adolescent Adult