Lidocaine levels in plasma for therapeutic monitoring purposes were compared by using fluorescence polarization immunoassay (Abbott TDx), enzyme immunoassay (EMIT-Cad), and a high-resolution gas chromatography (HRGC). The two immunoassay methods on 29 clinical samples gave excellent correlation (r = 0.998 and 0.999 for TDx and EMIT, respectively), when compared to the HRGC method.
Chromatography, Gas Fluorescence Polarization