Twenty-one patients with acute leukaemias were studied carrying out cytological investigations of the cerebrospinal fluid and then postmortem neuropathological examinations. The aim of the study was a comparison of these results. No correlation was demonstrated between CSF changes and the extent and location of leukaemic infiltrates in the meninges and the brain. In cases of subarachnoid haemorrhage the intensity of CSF changes was proportional to the extent of subarachnoid haemorrhage but was independent of its location.
Adolescent Adult