The disposition of polychloro-[1-14C]hexadecane (PCHD, 34% chlorine w/w) was studied in carp (Cyprinus carpio) and bleak (Alburnus alburnus). After intra-arterial (i.a.) injection in carp about 6% of dose was excreted as 14CO2 in 96 h. The autoradiographic distribution pattern after administration of PCHD to carp (i.a.) and bleak (up to 14 days of exposure in PCHD-contaminated water) was characterized by a strong labelling in the bile/intestinal contents. High radioactivity also appeared in the kidney, liver, gills and, particularly in bleak, in the nasal cavity, lens and skin.
Animals Autoradiography