We describe the synthesis and the antiulcer activity of new 11-deoxy-8-aza-PGE1 analogues (III a) and its C15-epimer (III b), (IV a) and its C15-epimer (IV b), featured by a triple bond in place of the C13-C14 trans double bond and a 16,16-dimethyl-17-oxabutyl omega-chain, respectively.
Animals Anti-Ulcer Agents