Diversity-oriented synthesis presents many formidable challenges to the practitioners of synthetic organic chemistry. Those challenges include the effective teaching of this new and evolving discipline to ensure that students are well positioned to begin exploring its full potential. Fortunately, the teaching of synthetic organic chemistry has a rich history in the context of target-oriented synthesis, and this precedent can serve as a strong foundation for meeting the challenges of teaching diversity-oriented synthesis.
Alkylation Chemistry, Organic