OBJECTIVE: To discuss the possible mechanism of drug resistance transmission between Staphylococcus and Escherichia coli.METHODS: The chloramphenicol resistance plasmid of Staphylococcus aureus was extracted to transform the sensitive Escherichia coli, and the drug-resistant Escherichia coli were screened by drug sensitivity test.RESULTS: The drug-resistant Escherichia coli were successfully obtained.CONCLUSION: Staphylococcus may have a natural shuttle plasmid of drug resistance, which can transform Escherichia coli under specific conditions.
Drug Resistance, Bacterial Escherichia coli