The function of microphages has been studied in vitro in a 5 year-old girl with Papillon-Lef?vre syndrome. The results showed a weakness in chemotatic activity, a defect of intracellular killing of Staphylococcus aureus, and an almost normal phagocytosis but decreased intracellular killing of Candida albicans by the microphages.
Chemotaxis, Leukocyte Child, Preschool