INTRODUCTION: Candida arthritis in premature infants is a rare condition mainly treated with parenteral amphotericin B.CLINICAL PICTURE: Arthritis 9 weeks after birth. The infection resulted out of colonisation at birth and fungaemia at day 6 and day 13 of life.TREATMENT: Oral fluconazole for 6 months (5 mg/kg/day after loading with 7 mg/kg/day).OUTCOME: Full remission.CONCLUSIONS: Oral fluconazole is an alternative to parenteral amphotericin B in the treatment of premature infants, but proof of absorption and an extended treatment period according to prematurity might be warranted.
Administration, Oral Antifungal Agents