The distribution of NADPH-diaphorase was studied cytochemically in the rabbit cerebellar cortex. In the granular layer the Golgi cells with positive reaction were found. The highest activity of enzyme was observed in the cytoplasm of intermediate cells of Lugaro, synaptic neurons of Landau, large and middle sized Golgi cells and intercalate cells of Pensa. It is concluded that the Lugaro and Golgi cells may metabolize nitric oxide to be NO-ergic in their mediator specialization.
Animals Cerebral Cortex