OBJECTIVE: To observe the effect of Banxia Xiexin Decoction (BD) and its components in the rats with electrogastric dysrhythmia, explore the mechanism of BD' s "relieving distension and fullness, and dissolving lumps" and study BD' s compatibility regularity.METHODS: Rat model of electrogastric dysrhythmia was established, the effects of BD and its components on the coefficient of variability of the model' s slow wave electrogastric rhythm were determined.RESULTS: Compared with the model group, BD and all the components groups had better effects on all the aspects (P <0. 05 ), Among which the group containing herbs with pungent and bitter flavour (Rhizoma Pinelliae, Rhizoma Zingiberis, Radix Scutellariae, Radix Berberidis julianae) was the best.CONCLUSION: BD and all the components have the effects of rectifying electrogastric dysrhythmias in various degrees, and the herbs with pungent and bitter flavour are best. This study provides the experimental foundations for further understanding the mechanism of BD' s treating principle-using bitter drugs for purgation and pungent drugs for dispersion, normalizing the functional activities of qi.
Animals Digestive System