OBJECTIVE: To compare the efficacy of oral dydrogesterone with that of micronized vaginal P gel and micronized P capsule for luteal supplementation.DESIGN: Prospective, randomized clinical study.SETTING: Institute of Reproductive Medicine, Kolkata, India.PATIENT(S): A total of 1,373 infertile women undergoing IVF participated.INTERVENTION(S): Micronized P gel, P capsule, and oral dydrogesterone were administered for luteal support and compared.MAIN OUTCOME MEASURE(S): Demographic profile and pregnancy and miscarriage rates.RESULT(S): The overall pregnancy rate and miscarriage rate were comparable among the three groups.CONCLUSION(S): Oral dydrogesterone seems to be a promising drug for luteal support in woman undergoing IVF.
Abortion, Spontaneous Administration, Intravaginal